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117 articles for “Molecular biology”
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Gold Nanoparticle Size, Biodistribution, and Toxicity: Insights from DualEnergy CT
Abstract: Dual-energy and spectral computed tomography (CT) have emerged as powerful platforms for noninvasive, quantitative mapping of nanoparticle biodistribution in vivo. By exploiting the energy-dependent attenuation profiles of high-atomic-number (high-Z) materials, these systems enable material decomposition and element-specific imaging, thereby distinguishing nanoparticle signals from those of soft tissues and conventional iodinated contrast agents. Photon-counting spectral CT further enhances this capability by binning individual photons into multiple energy channels, improving spatial resolution, …
Published in Nano Trends – A Journal of Nano Technology & Its Applications · Vol. 28, Issue 2, 2025 Read article
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Synthesis and antibacterial studies of some bivalent transition metal ions Zn (II), Cu (II) and Ni (II) complexes of Schiff’s base derived from some substituted aromatic aldehydes.
Abstract: In this study, Schiff bases were synthesised through the condensation of aromatic aldehydes with primary amines and subsequently complexed with Ni(II),Zn(II) and Cu(II) ions. The formation of the metal complexes was confirmed by FTIR spectroscopy, which identified the key functional groups involved in coordination. The biological activity of the prepared compounds were studied with the help of selected bacteria like E. coli , Pseudomonas. and B. sereus.. The results obtained …
Published in Journal of Modern Chemistry & Chemical Technology · Vol. 16, Issue 2, 2025 · pp. 96–104 Read article
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A Review on the Interconnection Between Drug Design and Controlled Drug Delivery Systems
Abstract: Drug discovery and delivery are two branches of science that have historically developed as independent areas of discovery – one focused on optimizing the properties of molecules for biological activity, and the other on controlling the rate, site, and duration for drug release. However, in contemporary pharmacy, these two areas have merged into a single integrated approach – where drug discovery and delivery strategies co-influence each other at each point …
Published in Emerging Trends in Personalized Medicines · Vol. 3, Issue 1, 2026 · pp. 47–52 Read article
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Exploring Phytochemicals from Ricinus Communis for Potential Therapeutic Applications in Rheumatoid Arthritis: An in-Silico Approach
Abstract: Aim: Rheumatoid arthritis (RA) is a long-term autoimmune condition characterized by the immune system mistakenly attacking the joints, leading to swelling, discomfort, and joint deformities. Current management strategies include anti-rheumatic drugs and biologics, which have limitations. This study aims to explore the therapeutic potential of Ricinus communis (castor bean plant) phytochemicals as plant-based therapies for autoimmune conditions, like RA. Methods: Phytochemicals from Ricinus communis were retrieved using the IMPPAT database, …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 3, Issue 1, 2025 · pp. 32–41 Read article
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Magnetic ZnxFe2–xO3 Nanoparticles Enhanced Nanobiosensor Integrated with MOSFETs for Efficient Detections of Biomolecules and Cancerous Cells
Abstract: The human brain is mostly responsible for intelligence and consciousness. An artificial equivalence of this action is nanobiosensor, which is used in artificial intelligence. The need for nanodiagnostics platforms for detecting diseases at the genetic, molecular, and cellular level has triggered the development of nanobiosensors integrated with MOSFETs. This device enables simple, inexpensive rapid tests, accurate imaging methods, and accurate molecular diagnosis at point-of-care (POC). This device is seen as …
Published in Journal of Nanoscience, NanoEngineering & Applications · Vol. 14, Issue 3, 2024 · pp. 33–44 Read article
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Precision Medicine Approaches for Cancer Therapy Recent and Advance
Abstract: Recent advances in biotechnology have made it possible to identify intricate and distinctive biological characteristics linked to carcinogenesis. Proteomic and RNA studies, immunological markers, tumor and cell-free DNA profiling, and other methods are utilized to find these traits in order to optimize anticancer treatment for specific patients. In recent years, the focus of clinical trials has shifted considerably to enhance treatment outcomes in cancer therapy. Rather than being primarily centered …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 14, Issue 1, 2025 · pp. 1–11 Read article
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Extracellular Vesicle-Based Liquid Biopsies: Decoding the Tumor Microenvironment for Precision Oncology
Abstract: The tumor microenvironment (TME) plays a pivotal role in cancer initiation, progression, and therapeutic response. Decoding the TME is, therefore, essential for advancing precision oncology. Extracellular vesicles (EVs), including exosomes and microvesicles, are nanoscale lipid bilayer particles secreted by tumor and stromal cells. They transport a wide range of bioactive molecules, such as DNA, RNA, proteins, lipids, and metabolites, which reflect the dynamic state of the TME. Recent advances in …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 15, Issue 1, 2026 · pp. 43–62 Read article
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A Comprehensive Study of ZnxFe2-xO3 Nanoparticles: Assessing Magnetic Properties for Medical Imaging (MI)
Abstract: Diluted magnetic ZnxFe2-xO3 nanoparticles are special semiconducting nanoparticles which are recognized for their magnetic properties. A theoretical examination of Zn-doped αFe2O3 nanostructures reveals a range of structural and property variations, offering insights into their potential applications and behavior at the nanoscale. In this regard, Heisenberg’s model and Weiss molecular filed theory is used to describe the magnetic properties of ZnxFe2-xO3 nanoparticles. These theorems inevitably enable to investigate the relationship between …
Published in Nano Trends – A Journal of Nano Technology & Its Applications · Vol. 26, Issue 2, 2024 · pp. 18–25 Read article
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Quorum Sensing and Biofilm Dynamics in Pathogens: An Evolving Frontier in Infectious Disease
Abstract: Bacterial and fungal pathogens rarely act as solitary invaders. Instead, they engage in sophisticated chemical communication known as quorum sensing (QS) to coordinate population-wide behaviours and construct structured, multicellular biofilm communities. These biofilms, composed of extracellular polymeric substances, not only facilitate microbial persistence on biotic and abiotic surfaces but also confer remarkable protection against host immune defenses and antimicrobial therapies. QS systems act as central regulators of biofilm dynamics, orchestrating …
Published in International Journal of Pathogens · Vol. 3, Issue 1, 2026 · pp. 18–23 Read article
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Synthesis of Silver Nanoparticles of Cissus Quandrangularis and It’s Virtual Screening Against Gastric Cancer
Abstract: Gastric cancer, also known as stomach cancer, is the third leading cause of cancer-related deaths globally and remains a major health challenge due to its poor prognosis and high mortality, largely attributed to late-stage diagnosis. In this context, plant-based nanomaterials are gaining momentum for targeted therapeutic applications. Cissus quadrangularis, a medicinal plant native to India from the Vitaceae family, is traditionally used for its diverse healing properties. Its stem, in …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 1551–1569 Read article
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Nano‑Enabled CT for Cancer Imaging: From Molecular Targeting to Image‑Guided Therapy
Abstract: Nano‑enabled computed tomography (CT) exploits high‑atomic‑number (high‑Z) nanomaterials engineered with targeting ligands and therapeutic payloads to enhance contrast, enable molecular imaging, and support image‑guided interventions in oncology. Tumor‑specific nanoprobes such as RGD‑modified gold nanorods, polymer‑coated bismuth nanoparticles, and peptide, antibody, or aptamer‑functionalized platforms can intensify tumor conspicuity, allow early lesion detection and staging, and provide real‑time treatment monitoring. Integration of CT visibility with photothermal, photodynamic, chemo‑, radio‑, and immunotherapeutic functions …
Published in Nano Trends – A Journal of Nano Technology & Its Applications · Vol. 28, Issue 1, 2025 · pp. 40–49 Read article
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Study of Electrically Conductive Polymer for Antistatic and Sensor Application
Abstract: Electrically conductive polymers (ECPs) are a unique category of smart materials that integrate the mechanical flexibility and ease of processing characteristic of conventional polymers with the electrical conductivity typically associated with metals or semiconductors. In recent years, they have attracted considerable interest due to their promising potential in advanced technological applications, especially in antistatic coatings and electronic sensing devices. The unique ability of these polymers to conduct electricity arises from …
Published in International Journal of Minerals · Vol. 3, Issue 1, 2026 · pp. 46–51 Read article
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Biopolymer Degradation and Structure–Property Relationships in Ageing: A Polymer Science Perspective
Abstract: Ageing, as viewed from the polymer sciences perspective, is perceived as the gradual modification of the structure-property-function interrelationship of biopolymers such as proteins, polysaccharides, nucleic acids and their molecular aggregates. Such changes include structural organization, mechanical behavior, physicochemical stability and functional effectiveness. Ageing is an inevitable multifactorial polymeric process. Due to the growing aging population globally, more age-associated complications emerge, which are correlated with the molecular degeneration of biopolymeric complexes. …
Published in Journal of Polymer & Composites · Vol. 14, Issue 3, 2026 · pp. 479–489 Read article
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Paternal Pre-Pubertal Smoking: Small RNAs, Lasting Marks, and the Hidden Legacy of Early Exposure
Abstract: While the negative effects of maternal smoking during pregnancy are well-established, the lasting and transgenerational impact of paternal pre-pubertal smoking remains a critical, underexplored area. Emerging evidence in sperm epigenetics suggests that cigarette exposure during early male development may create persistent molecular imprints that can affect the health of future offspring. This phenomenon is rooted in the fact that heredity extends beyond the DNA sequence. Sperm carry a complex epigenetic …
Published in Emerging Trends in Personalized Medicines · Vol. 3, Issue 1, 2026 · pp. 1–5 Read article
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Studies on the Self-Assembly of Steroids and DNA Mediated by Naphthalene based Amphiphilic Block Copolymer
Abstract: Amphiphilic block copolymers have attracted considerable interest in pharmaceutical and biomedical applications, including controlled drug release, gene delivery, and biomolecular sensing. In this study, fluorescent amphiphilic block copolymers were designed to facilitate interactions with biological molecules such as DNA and antiviral agents, enabling their behavior to be monitored through fluorescence spectroscopy. Two novel block copolymers, poly(methyl methacrylate) - b - poly(dimethylaminoethyl methacrylate - co - naphthyl methacrylate) [PMMA-b-P(DMAEMA-co-NMA)] and poly(styrene) …
Published in Journal of Polymer & Composites · Vol. 14, Issue 5, 2026 Read article
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Synthesis and Spectral Characterization of Complexes Tin(II) With 4-Nitrophenol
Abstract: Tin(II)4-nitrophenoxide complexes with the formulas SnCl(OC₆H₄NO₂-4) and Sn(OC₆H₄NO₂-4)₂ were prepared through the reaction of stannous chloride (SnCl₂) with 4-nitrophenol (HOC₆H₄NO₂-4) in 1:1 and 1:2 molar ratios, respectively. The reaction was performed in tetrahydrofuran (THF) with diethylamine serving as the base. The resulting compounds were characterized through elemental analysis, determination of molecular weight, molar conductance measurements, and spectroscopic methods including IR and ¹H NMR spectroscopy. Current investigations are directed toward assessing …
Published in International Journal of Advance in Molecular Engineering · Vol. 4, Issue 1, 2026 · pp. 22–26 Read article
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Medically Important Hemiptera: Bed Bugs and Kissing Bugs in Human Health.
Abstract: Bed bugs (family Cimicidae) and kissing bugs (subfamily Triatominae) are hematophagous Hemiptera of major medical importance, yet they differ markedly in their public health impact. Bed bugs have resurged globally over the past three decades, with infestations reported from homes, multi-unit housing, hotels, transportation, and healthcare facilities in both high and low-income settings. They are not established biological vectors of human pathogens, but their bites cause pruritic papules, urticarial, and …
Published in International Journal of Insects · Vol. 3, Issue 1, 2026 · pp. 41–49 Read article