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227 articles for “Genetics of the Disease”
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Association Rule Mining for Predicting Heart Disease: Challenges and Opportunities
Abstract: The exponential growth of digital healthcare data has spurred innovative applications of data mining techniques in medical research and practice. Among these, association rule mining stands out for its ability to uncover meaningful correlations within diverse datasets, such as electronic health records, imaging data, and genetic information. This paper reviews the application of association rule mining in predicting heart diseases, emphasizing its potential to enhance early detection, risk stratification, and …
Published in Journal of Advanced Database Management & Systems · Vol. 11, Issue 3, 2024 · pp. 29–34 Read article
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Importance of Dental Genomics
Abstract: The Genetics and Genomics got matured in several ways and domains in order to improve accuracy of the disease identification, disease management, knowing possible risks, reducing the chances of relapse etc. The Genomics development in medical field is really very impactful as the outcome directly reflects in patients’ quality of life. As the dental genetics is been for while in order to know and understand genes which are responsible for …
Published in Research and Reviews: A Journal of Dentistry · Vol. 13, Issue 2, 2022 · pp. 16–21 Read article
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Molecular Docking of Arjuna Tree Phytocompounds for Ischemic Heart Disease
Abstract: Heart disease is a serious condition that can be caused by several lifestyle changes and sometimes genetic problems. The primary protein component of apolipoprotein is the LDL receptor, which indicates that a reduction in LDL levels can reduce the risk of ischemic heart disease. Apolipoprotein levels are associated with increased levels of ischemic heart disease. Using ADMET analysis, drug likelihood prediction, and molecular docking, this work attempted to find natural …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 3, Issue 1, 2025 · pp. 42–52 Read article
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Structure and Origin Insight of Recent Coronavirus with Ongoing Therapeutic Approach
Abstract: Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is highly transmissible zoonotic virus that was initially reported in late 2019 in Wuhan, China. Presently, it has infected approximately 1.5 million person and responsible for more than 0.1 million death across the world. It is likely evolved from bats and pangolin and genetically different from SARS-CoV-1, responsible for SARS disease. In present review, we have discussed the recent finding of its origin from …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 10, Issue 4, 2020 · pp. 34–47 Read article
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Cervical Cancer: Understanding Its Causes, Risk Factors, and Preventive Measures
Abstract: Cervical cancer is a form of cancer that begins in the cervix, the lower portion of the uterus, due to abnormal cell growth that can spread or invade other areas of the body. In its early stages, cervical cancer usually shows no obvious symptoms, which is why regular screenings are essential for detecting it early. As the cancer advances, symptoms such as pelvic pain, unusual vaginal bleeding, and pain during …
Published in International Journal of Oncological Nursing and Practices · Vol. 3, Issue 1, 2025 · pp. 26–30 Read article
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Nutritional Status among Adolescents: Contributing Factors
Abstract: Nutritional status of adolescents is of much concern. Faulty eating habits can make them overweight and ultimately obese and even malnourished also. Obesity is a complex disorder involving an excessive amount of body fat. Obesity is not just a cosmetic concern; it increases the risk of diseases and health problems. There are various factors like biological, genetic, behavioural and environmental which contribute to obesity. An exploratory design was used to …
Published in Research and Reviews: A Journal of Health Professions · Vol. 6, Issue 3, 2016 · pp. 5–10 Read article
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Transforming Rare Disease Diagnosis with AI
Abstract: Artificial intelligence is changing healthcare fast. It is making diagnoses accurate, helping doctors get better results, and streamlining how care works. This paper looks at how AI shows up in healthcare right now – where it is already making a difference, what is working, and what is still tricky. The focus is on machine learning, natural language processing, and computer vision. Particular attention is given to using AI in diagnosing …
Published in Research and Reviews : Journal of Computational Biology · Vol. 15, Issue 1, 2026 · pp. 31–40 Read article
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Reproductive Challenges in Tropical Dairy Cows: Exploring Stressors and Mitigation Strategies for Sustainable Development
Abstract: Reproductive efficiency in tropical dairy cows is often compromised by a range of environmental, nutritional, and management-related stressors. These stressors, including heat, humidity, poor-quality feed, disease, and parasitic infestations, significantly affect fertility, leading to prolonged calving intervals, reduced conception rates, and increased reproductive disorders. Heat stress, in particular, has been identified as a primary factor influencing reproductive performance by disrupting hormonal balance, reducing feed intake, and impairing overall cow health. …
Published in Research and Reviews : Journal of Veterinary Science and Technology · Vol. 15, Issue 2, 2026 · pp. 7–26 Read article
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Screening of Mustard Varieties and Lines against Clubroot and Alternaria Leaf Spot Diseases
Abstract: The experiment was conducted to find out the resistant varieties/lines against clubroot and Alternaria leaf spot diseases of mustard at the Plant Pathology Division, RARS Jamalpur, Bangladesh during the Rabi season of 2024-2025 with sixty-two (62) varieties and lines of Mustard collected from Oilseed Research Centre (ORC) and Plant Genetic Resources Centre (PGRC), Joydebpur, Gazipur-1701, Bangladesh. To screen for clubroot and Alternaria leaf spot diseases and to evaluate yield and …
Published in Research & Reviews : Journal of Agricultural Science and Technology · Vol. 14, Issue 3, 2025 · pp. 97–106 Read article
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Cognitive Impairment in Alzheimer’s Disease
Abstract: Alzheimer's disease (AD) is a condition that leads to the deterioration of brain cells and is the primary cause of dementia, characterized by a decline in autonomy and cognitive function in day-to-day activities. The cholinergic hypothesis and the amyloid hypothesis are the two main theories proposed to explain AD's multifaceted nature. Characterized by a decline in autonomy and cognitive function in day-to-day activities. The cholinergic hypothesis and the amyloid hypothesis …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 16, Issue 3, 2026 Read article
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Epigenetic Regulation and Plasticity in Human Diseases
Abstract: In normal human development as well as in the case of diseased development, epigenetic changes are involved. The role of plasticity is important and directed on the understanding feature of epithelial cell biology, and maybe a significant pathway for disease pathobiology and pathogenesis. During embryonic development, an epigenetic mechanism is important for the growth and development of genetically identical cells that are obtained from different outcomes. In this review study, …
Published in Research and Reviews : A Journal of Immunology · Vol. 11, Issue 1, 2021 · pp. 12–20 Read article
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GenChrome-ML: A Machine Learning Framework for Early Detection of Chromosomal Disorders Using Genomic Data
Abstract: The increasing burden of chronic disease and cancer demands innovative, more rapid and effective diagnostic tools in the field of healthcare. The majority of current diagnostic tools are dependent upon clinical symptomology and manual evaluation, leading to delays in early detection and treatment. The development of artificial intelligence (AI) and machine learning (ML), in recent years, has offered opportunities for the enhancement of disease prediction, diagnosis and personalization of treatment …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 4, Issue 2, 2026 Read article
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Understanding Metabolic Syndrome and its Nutritional Management
Abstract: Metabolic syndrome (MetS) is a collection of risk factors, especially when at least three occur together, including abdominal obesity, dyslipidemia, low high-density lipoprotein cholesterol (HDL-c) levels, hypertension, and insulin resistance. MetS is linked to an increased risk of diabetes and cardiovascular diseases (CVDs) if treatment is not received.The causes of MetS include both genetic and acquired factors that contribute to issues such as insulin resistance, chronic low-grade inflammation, and obesity. …
Published in International Journal of Sustainability · Vol. 2, Issue 1, 2025 · pp. 26–37 Read article
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Epigenetic Modifications in Health, Disease, and Precision Therapeutics (From Genome to Epigenome)
Abstract: Introduction: Epigenetic alterations play a crucial role in regulating gene expression in both normal physiological and disease states. These reversible modifications—such as DNA methylation, histone acetylation, phosphorylation, ubiquitination, and chromatin remodelling—are increasingly implicated in complex diseases including cancer and neurodegenerative disorders. Despite advances in standard therapeutic approaches, patient responses remain variable, largely due to genetic heterogeneity and epigenetic dysregulation. This highlights the need for incorporating epigenetic understanding into personalized medicine. …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 15, Issue 1, 2026 Read article
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The Rising Burden of Heart Attacks: Causes, Trends, and Prevention Strategies
Abstract: Heart attacks, or myocardial infarctions, remain a leading cause of morbidity and mortality worldwide, with their incidence rising steadily across diverse populations. This review explores the increasing prevalence of heart attacks, emphasizing traditional risk factors, such as poor diet, physical inactivity, smoking, and medical conditions like hypertension, diabetes, and hyperlipidemia. It also highlights emerging risk factors, such as chronic infections, pollutants, substance abuse, and the lasting cardiovascular effects of COVID-19. …
Published in Research and Reviews : Journal of Surgery · Vol. 14, Issue 2, 2025 · pp. 1–11 Read article
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Adverse Drug Reactions: A Global Health Challenge
Abstract: Adverse drug reaction (ADR) is an unfavorable event with a causal connection to the medication. It is an undesirable event occurred by a pharmacological substance. They are a major cause of Mortality all over, they are classified into augmented, chronic, bizarre, Delayed based on the severity of the damage they caused The primary causes of adverse drug reactions (ADRs) are drug overdose, drug– drug interactions, genetic variations, and individual characteristics …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 16, Issue 2, 2026 · pp. 01–06 Read article
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Stability Study of Fine Powder of Gandhaka Kalpa and Gandhakadi Yoga in the Management of Thalassemia Major-With Respect to Baseline Microbial Diagnostic Modalities
Abstract: Thalassemia is a genetic blood disorder. Thalassemia is the most transfused syndrome worldwide. People with Thalassemia disease are not able to make enough hemoglobin, which causes severe anemia. According to the World Health Organization (WHO), the alpha and beta Thalassemia are the most common inherited single-gene disorders in the world. Adhishthana of the disease Thalassemia is the Beejabhagavayava, which is responsible for the formation of Rakta-Dhatu. Hence the Vyadhi can …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 10, Issue 3, 2020 · pp. 29–37 Read article
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Understanding the Efficacy of Homoeopathic Remedies in the Treatment of Psoriasis
Abstract: Psoriasis is a common chronic inflammatory skin disease with a spectrum of clinical phenotypes and results from the interplay of genetic, environmental, and immunological factors. As the holistic individualized homeopathic approach deals with the interplay of all the factors external and internal, an evidence-based study would help us understand its effectiveness. This prospective case series of thirty cases of Psoriasis attempts to understand the efficacy of homoeopathy using psoriasis area …
Published in Research & Reviews : A Journal of Unani, Siddha and Homeopathy · Vol. 9, Issue 1, 2022 · pp. 6–10 Read article
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In Silico Tau Protein Kinase I Inhibitory Activity of Some Commercially Available Flavonoids
Abstract: Molecular docking is a frequently used tool in computer-aided structure-based rational drug design. Flavonoids are a group of natural products which exhibits various biological and pharmacological activities. The primary objective of this study was to investigate the tau protein kinase I inhibitory activity of flavonoids using in silico docking studies. Memantine, a known neuro-receptor antagonist is currently used in the treatment of Alzheimer’s disease (AD). In silico docking studies were …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 2, Issue 1, 2015 · pp. 6–12 Read article
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ECZEMA {Atopic Dermatitis}
Abstract: Many of the persons around the world suffer from eczema which is also called atopic dermatitis. It is a kind of skin disorder that makes the skin dry, itchy, and sometimes even painful. There is no specific age group who got affected by this particular disease, no matter what age you are. But particularly it is seen that the children were mostly affected by eczema, as there is no cure …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 1, Issue 1, 2023 · pp. 53–66 Read article