Search
332 articles for “Gene medicine”
-
CRISPR-Based Enhancement of Secondary Metabolites in Artemisia annua: Focus on Artemisinin Biosynthesis
Abstract: Medicinal plants are natural biofactories producing secondary metabolites with significant therapeutic value, including terpenoids, alkaloids, and phenolics. Among these, artemisinin, a sesquiterpene lactone from Artemisia annua L. is the cornerstone of global antimalarial therapy along with additional anticancer, antiviral, and antimicrobial activities. However, artemisinin content in the native plants is inherently low (typically 0.01–0.8% dry weight), restricting affordable and consistent supply. Conventional approaches to increase production include classical breeding, singlegene …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 16, Issue 2, 2026 · pp. 23–35 Read article
-
Drug Utilization Study of Anti Rheumatoid Drugs in Patients with Rheumatoid Arthritis at a Tertiary Care Hospital
Abstract: Background: Rheumatoid arthritis (RA) is a chronic disease that is classified as an autoimmune illness. It is characterized by joint inflammation, which can subsequently cause joint destruction. This leads to disability and a decline in quality of life. An analysis of drug usage is an important way of assessing prescribing habits and evaluating the rationality of drug use in an effort to achieve optimal therapeutic results among RA patients. Objectives: …
Published in International Journal of Orthopedic Nursing and Practices · Vol. 4, Issue 1, 2026 · pp. 14–20 Read article
-
Shiqaq-e-Maqad (Fissure in Ano) As Per Unani System of Medicine
Abstract: Anal fissure is one of the most common anorectal condition encountered in clinical practice. It is a longitudinal split in the anoderm, with surrounding oedema and inflammatory induration which causes painful defecation, bleeding with streaks of blood on the surface of stool or on toilet paper and itching per rectum. As per Modern aspect, the aetiology of anal fissure is not known. They generally arise with local trauma caused by …
Published in Research & Reviews : A Journal of Unani, Siddha and Homeopathy · Vol. 7, Issue 2, 2020 · pp. 28–33 Read article
-
Personalized Medicines in Pharmaceutics: Drug Delivery System
Abstract: Pharmaceutics personalized medicine is a developing area that seeks to customize medical interventions for specific patients. Instead of a one-size-fits-all approach, personalized medicine focuses on developing treatments that consider a person’s unique characteristics, such as their genetic makeup, environment, and lifestyle. This allows for more effective treatment outcomes, as drugs are specifically designed to work best for each patient, reducing side effects and improving therapeutic results. In pharmaceutics, this involves …
Published in Emerging Trends in Personalized Medicines · Vol. 2, Issue 1, 2025 · pp. 11–22 Read article
-
Nanoparticles in Cutting-edge Healthcare: Current Use and Emerging Issues
Abstract: Nanoparticles are sub-micron-sized particles (less than 100 nm on average). Using these materials as contrast agents in imaging and as carriers for medication and gene transfer into malignancies has given them a prominent place in contemporary medicine. Nanoparticles allow for previously inconceivable levels of analysis and therapy. However, nanoparticles provide new societal and environmental challenges, especially regarding toxicity. In this overview, we discuss how nanoparticles have benefited contemporary medicine and …
Published in Journal of Polymer & Composites · Vol. 11, Issue 3, 2023 · pp. 105–118 Read article
-
General Notion of Temperament
Abstract: and retort by their energy, then previous potentials become reduced. The concept of temperament is the column of Unani Medicine. This concept was firstly introduced by Hippocrates when he specified that “It is more important to know what category of person a disease has then to know that sort of disease a person has”. Galen reflected that one pair of qualities out of four possibilities was main leading to the …
Published in Research and Reviews : A Journal of Ayurvedic Science, Yoga and Naturopathy Read article
-
Expression Profiling of Immunomodulatory Genes in Canine Adipose Tissue–Derived Mesenchymal Stem Cells
Abstract: Adipose tissue–derived mesenchymal stem cells (AT-MSC) represent a heterogeneous population of self-renewing, multipotent progenitor cells residing in the stromal compartment of adipose tissue. Canine adipose tissue-derived mesenchymal stem cells have attracted significant interest in regenerative medicine due to their therapeutic potential in naturally occurring canine diseases and their translational relevance to human medicine. In the present study, canine adipose tissue–derived MSCs (cAT-MSCs) were isolated and differentiated into osteogenic, chondrogenic and …
Published in Research and Reviews : Journal of Veterinary Science and Technology · Vol. 15, Issue 1, 2026 Read article
-
Crispr Cas – Revolutionizing Modern Therapies and Beyond
Abstract: CRISPR-Cas technology has emerged as a transformative tool in modern molecular biology, revolutionizing both fundamental research and clinical applications. This RNA-guided gene-editing system enables precise and efficient genomic modifications, offering unprecedented potential for addressing genetic disorders, infectious diseases, and oncological conditions through innovative therapeutic interventions. The inherent specificity and programmability of CRISPR-Cas systems have facilitated breakthroughs in diverse fields, including precision medicine, regenerative therapies, and immuno-oncology. Beyond its therapeutic applications, …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 3, Issue 1, 2025 · pp. 25–38 Read article
-
Concept of Low Back Pain (Waja-uz-Zahr) in Unani System of Medicine
Abstract: Waja-uz-Zahr (low back pain) is marked as most costly ailment in the productive years. Low back pain (LBP) has been cited as the 2nd most common reason for which patients visit a physician. It is the major cause of activity restriction and work absence all over the world. It causes an enormous financial load on individuals, families, communities, industry and governments. The prevalence of back pain in the adult population …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 9, Issue 3, 2020 · pp. 13–17 Read article
-
Use of Gold in Crown and Bridge Procedures: The Most Versatile Restorative Material in Dentistry: A Review and Commentary
Abstract: Use of gold restorations has been almost forgotten in dentistry. They are no longer a part of most dental training curricula or often employed in private practice. Gold restorations are usually overlooked on most patient treatment plans in modern dentistry largely due to the following misconceptions: Gold is too expensive for use as a dental material. Nonetheless, the price of an ounce of gold in recent months has been at …
Published in Research and Reviews: A Journal of Dentistry · Vol. 7, Issue 1, 2016 · pp. 36–40 Read article
-
A Systematic Review of the Herbal Medicinal Plants With Anti-Obesity Potential
Abstract: Obesity is a chronic, multifactorial metabolic condition characterized by abnormal fat accumulation. It is mainly driven by the intricate influence of genetic, environmental, hormonal, metabolic and lifestyle determinants. The burden of obesity has risen considerably over the past few years, making it one of the major health concerns in both developed and developing countries alike. The rapid increase globally in obesity prevalence is linked with numerous health complications such as …
Published in Research & Reviews : Journal of Herbal Science · Vol. 15, Issue 2, 2026 · pp. 31–38 Read article
-
The Role of Bioinformatics in Nursing: Transforming Healthcare through Data-Driven Insights
Abstract: Bioinformatics, an interdisciplinary field combining biology, computer science, and information technology, is increasingly shaping the nursing profession. It offers powerful tools for improving patient care, advancing clinical research, and enabling personalized healthcare through data-driven decision-making. This article examines the integration of bioinformatics into nursing practice, tracing its historical roots from the Human Genome Project to its current applications in genomic medicine, precision healthcare, and population health. Nurses now play a …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 11, Issue 3, 2024 · pp. 18–21 Read article
-
Potential, Principles, and Applications of Microwave Energy
Abstract: Microwave energy 300 MHz to 300 GHz electromagnetic radiation is essential to modern science and technology. Its applications include telecommunications, medicine, industrial processing, and renewable energy, despite its association with kitchen appliances. Microwave energy generation, transmission, and material interaction are covered in this article. It emphasises wireless communication, radar, medical therapies, and microwave- assisted chemical processes. The study also examines new developments in microwave engineering, such as the creation of …
Published in Journal of Microwave Engineering and Technologies · Vol. 13, Issue 1, 2026 · pp. 34–39 Read article
-
Emerging Therapies in Respiratory Tract Infections: Current Advances and Future Perspectives
Abstract: The impact of respiratory tract infections (RTI) as a global public health problem continues to be high morbidity and mortality rates. The development of novel therapeutic approaches stemmed from the fact that conventional treatment strategies, antibiotics, antivirals, antifungals etc. have become increasingly ineffective because of rise of antimicrobial resistance (AMR). Next generation therapies, such as novel antimicrobial agents, host directed therapies and novel drug delivery systems have come on the …
Published in Recent Trends in Infectious Diseases · Vol. 2, Issue 2, 2025 · pp. 17–25 Read article
-
Personalized Nutrition and Exercise: Pioneering the Path to Precision Medicine
Abstract: Preventive healthcare is about to undergo a major shift thanks to the personalised exercise and nutrition paradigm, which is based on precision medicine concepts. In order to create tailored recommendations for improving health outcomes and preventing chronic diseases, this article explores the integration of genetic profiling, metabolic evaluation, and lifestyle factors. A person's response to food and exercise depends heavily on genetic and metabolic variances, which emphasises the need of …
Published in Emerging Trends in Personalized Medicines · Vol. 1, Issue 2, 2024 · pp. 42–46 Read article
-
Unani Medicine: Decoding the Principles of Administration and Analyzing the Concept of Insomnia (Sahr)
Abstract: Insomnia, known as Sehar in the Unani system of Medicine, refers to the condition of being unable to fall asleep or stay asleep, primarily caused by an imbalance in the brain's temperament due to excessive Hararat and Yaboosat. It is recognized as a risk factor for depression and is more prevalent in women. Insomnia, or sleeplessness, is a widespread issue worldwide and is characterized by difficulty in initiating or maintaining …
Published in Research & Reviews : A Journal of Unani, Siddha and Homeopathy · Vol. 10, Issue 3, 2023 · pp. 1–7 Read article
-
Digital Therapeutics for Management of Chronic Diseases
Abstract: Digital therapeutics (DTx) mark a major advancement in modern medicine, using advanced software technologies to deliver clinically validated treatments for various physical and mental health conditions. Unlike general wellness apps that focus on fitness or lifestyle tracking, DTx are evidence-based medical interventions developed through rigorous clinical research to ensure safety, efficacy, and measurable outcomes. Delivered via digital platforms such as smartphones, tablets, or specialized medical devices, DTx aim to prevent, …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 15, Issue 2, 2026 Read article
-
Factors Associated with Relapse in Schizophrenia Patients Who are on Follow Up at Ayder Comprehensive Specialized Hospital and Mekelle General Hospital, Tigray, Ethiopia, 2018/19
Abstract: Schizophrenia is a chronic and disabling illness; relapse is recognized as the reemergence or the worsening of positive and/or negative psychotic symptoms, hospital admission or readmission. Factors that associated with relapse; substance use disorders, noncompliance of medicine, side effect experience of antipsychotic, poor social support, co-morbidity of other mental illness and chronic medical condition. The aim of this study was to identify factors associated with relapse in schizophrenia patients who …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 10, Issue 1, 2020 · pp. 9–15 Read article
-
Comprehensive Healthcare, Key Achievements and Milestones at AYUSH Wellness Clinic, President’s Estate: A Report of Six Years of Functioning
Abstract: There has been a rapid transition in the health needs of our country from infectious diseases to chronic diseases and lifestyle disorders in the last few decades. Likewise, there has been a resurgence of interest in holistic systems of health care among the general public. The Government of India has emphasized establishment of specialty centers of Indian systems of medicine and Homeopathy. Taking this vision forward, Rashtrapati Bhavan with the …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 10, Issue 3, 2021 · pp. 7–12 Read article
-
Effect of Valuka Swedana with Dwipanchamuladi Basti in the Management of Hypothyroidism—A Case Study
Abstract: Due to sedentary life style and stress, the incidence of metabolic disorders is increasing day by day. Among these disorders, hypothyroidism is one of the commonest reasons in hospital visits. Hypothyroidism refers to any state that results in a deficiency of thyroid hormone, including hypothalamic or pituitary disease and generalized tissue resistance to thyroid hormone and disorders that affect the thyroid gland. The available allopathic medicine commonly prescribed by allopathic …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 6, Issue 2, 2017 · pp. 52–55 Read article