Search
1068 articles for “Selected”
-
Formulation Challenges in Long-acting Injectable Small Molecules: Emerging Strategies and Perspectives
Abstract: Long-acting injectable (LAI) formulations represent a transformative approach in pharmacotherapy, particularly for conditions demanding sustained drug exposure over weeks to months. Although biologics have dominated this space historically, the adaptation of LAI technology to small molecules presents a distinct and complex set of challenges rooted in physicochemical properties, manufacturing scalability, and regulatory expectations. This review systematically addresses the principal formulation barriers encountered in developing LAI small-molecule products, including aqueous solubility …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 13, Issue 2, 2026 Read article
-
Molecular Dynamics and Therapeutic Architectures of Cannabinoid Receptors: A Comprehensive Review
Abstract: Expanding on these foundations, recent structural biology studies using cryo-electron microscopy have provided high-resolution insights into the conformational dynamics of CB₁ and CB₂ receptors. These findings have enabled a more precise understanding of ligand–receptor interactions, particularly how agonists, antagonists, and reverse agonists stabilize distinct receptor states. Such knowledge is critical for rational drug design, allowing researchers to selectively modulate downstream signaling pathways. For instance, CB₁ receptors primarily couple to Gi/o …
Published in International Journal of Cheminformatics · Vol. 4, Issue 1, 2026 · pp. 36–40 Read article
-
Polymeric Micelles for Medicinal Plant Solubilization and Delivery of Bioactive Compounds
Abstract: This study involved the design, fabrication, and characterization of polymeric micellar nanocomposites utilizing amphiphilic block copolymers to effectively encapsulate and transport hydrophobic phytoconstituents. The selected bioactive molecule is curcumin, a polyphenol with limited water solubility. A polymeric system known as PEG-PCL was utilized to fabricate core-shell nanostructures by a solvent evaporation-induced self-assembly method. The resulting nanocomposites exhibited homogeneity and colloidal stability, characterized by a zeta potential of −18.7 ± 1.4 …
Published in Journal of Polymer & Composites · Vol. 14, Issue 3, 2026 · pp. 208–219 Read article
-
Iron Ore Beneficiation through Reverse Flotation: Advances in Nanobubble-Assisted Flotation Technology for Lean Grade Ore Upgradation and Silica Removal: A Review
Abstract: The global demand for high-grade iron ore concentrates continues to surge as readily available rich ores become depleted. Iron ore beneficiation through froth flotation has emerged as a critical technology for upgrading lean-grade iron ores (typically 25–35% Fe) to produce high-quality concentrates (64–70% Fe) suitable for direct reduction and blast furnace operations. This comprehensive review examines the fundamental principles of flotation in iron ore beneficiation, with particular emphasis on the …
Published in International Journal of Minerals · Vol. 3, Issue 1, 2026 · pp. 1–30 Read article
-
Experimental and Process Optimization Study on Thermal Stress Reduction in TiC–Steel Brazed Joints Using Polymer-Derived Composite Interlayers
Abstract: In this, an experimental investigation aimed at reducing crack formation due to thermal stress in TiC-steel brazed joints through optimization of key process parameters is presented. The primary objective was to develop an integrated and reliable brazing strategy by examining the effects of filler material selection, brazing gap, cooling conditions and type of flux. In this study, polymer-derived composite interlayers were developed through controlled synthesis and nanocomposite engineering to mitigate …
Published in Journal of Polymer & Composites · Vol. 14, Issue 3, 2026 · pp. 524–540 Read article
-
Machine Learning Assisted Design and Analysis of Polymer Composite Materials for Sustainable Renewable Energy Systems
Abstract: Accurate prediction and optimization of polymer composite properties is of paramount importance in the design of these lightweight, durable, and sustainable materials within renewable energy technologies. This work will provide a holistic machine learning-assisted framework that unites materials informatics with domain-specific features and state-of-the-art ML methodologies in the prediction of the mechanical properties of polymer composites, such as tensile strength. This includes embedding several ensemble models, including Random Forest and …
Published in Journal of Polymer & Composites · Vol. 14, Issue 3, 2026 · pp. 391–402 Read article
-
Polymer-Based Acoustic Composite Materials for Urban Noise Mitigation: Design, Performance and Legal Integration
Abstract: This study explores the development and use of polymer-based acoustic composite materials for effective urban noise mitigation, wherein the performance of the materials is linked to legal compliance frameworks. Rapid urbanization has intensified noise pollution from transportation, industrial activity, and construction, posing a serious threat to public health and environmental quality. Although regulatory standards exist, their implementation is often limited due to inadequate technical interventions. This research focuses on advanced …
Published in Journal of Polymer & Composites · Vol. 14, Issue 3, 2026 · pp. 403–412 Read article
-
Innovations in Mineral Science and Engineering for Sustainable Resource Development
Abstract: The growing global demand for mineral resources, coupled with increasing environmental and social concerns, has intensified the need for sustainable approaches in mineral science and engineering. Traditional mining and mineral processing practices, while essential for industrial development, are often associated with high energy consumption, resource depletion, and environmental degradation. In response, recent innovations in mineral science and engineering have focused on improving resource efficiency, minimizing environmental impact, and ensuring long-term …
Published in International Journal of Minerals · Vol. 3, Issue 1, 2026 · pp. 31–36 Read article
-
Design and Performance Evaluation of PLA-based Umbrella Wheels for Stair-Climbing Robotic Applications
Abstract: Staircase climbing robots require a complex design capable of navigating various stair configurations. A crucial component of such robots is the wheel mechanism. This paper focuses on the umbrella wheel mechanism and its application in staircase climbing robots. In this study, a PLA–based umbrella wheel structure is developed and fabricated using fused deposition modeling (FDM) for application in stair-climbing robots. The umbrella wheel geometry enables transformation from a circular rolling …
Published in Journal of Polymer & Composites · Vol. 14, Issue 3, 2026 · pp. 808–824 Read article
-
Design of Evaporator and Condenser for Solar Adsorption Refrigeration System
Abstract: Solar adsorption refrigeration systems provide a promising alternative for sustainable cooling in regions with limited grid access and high solar availability because they can convert low-grade thermal energy into refrigeration without mechanical compression. The performance of such systems depends strongly on the thermal behavior of the evaporator and condenser, since these components govern the refrigerant evaporation rate, condensation effectiveness, and overall cycle stability. This paper presents focus on the design …
Published in Journal of Refrigeration, Air conditioning, Heating and ventilation · Vol. 13, Issue 2, 2026 · pp. 1–10 Read article
-
Eco-Efficient Skies: Life Cycle Assessment and Carbon Footprint Minimization of Fiber-Reinforced Polymer Composites in Aerospace Application
Abstract: The increasing integration of fiber-reinforced polymer (FRP) composites in aerospace structures necessitates a rigorous evaluation of their environmental sustainability throughout their entire life cycle. This study presents a comprehensive life cycle assessment (LCA) and carbon footprint analysis of carbon fiber-reinforced polymer (CFRP) and glass fiber-reinforced polymer (GFRP) composites applied to structural and semi-structural components in commercial aerospace applications. Following ISO 14040/14044 standards and employing the ReCiPe 2016 Midpoint (H) impact …
Published in Journal of Polymer & Composites · Vol. 14, Issue 3, 2026 · pp. 147–160 Read article
-
Assessing Taila Bindu Pariksha as a Diagnostic and Prognostic test for Diabetes Mellitus
Abstract: Ayurveda has consistently emphasised on not just treatment of a disease but also how to diagnose it and further assess the prognosis. Ayurveda is blessed with different diagnostic tests which is broadly classified into Roga and Rogi Pariksha such as Ashtavidha Pariksha, Dashavidha Pariksha and Dwadashavidha Pariksha. These tests are used very rarely by just few Ayurvedic practioners as an important diagnostic and prognostic methods in different diseases. Taila Bindu …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 15, Issue 2, 2026 Read article
-
Post Covid-Sequela: Novel-Inception of DM: A Review
Abstract: As patients recovers from COVID 19 pandemic, a subset of the covid patients experienced a post covid condition with long term symptoms, few weeks after their discharge or recovery from the (SARS-CoV-2) infection. Hence, we tried to prove the hypothesis whether diabetes mellites is an afresh possible sequala of covid infection by systematically evaluating the consistently changing glucose level of the post covid patients. The databases PubMed and Google Scholar …
Published in Research and Reviews : A Journal of Immunology · Vol. 16, Issue 2, 2026 Read article
-
Influence of Antibiotic Promotion Practices on Pharmacovigilance and Resistance Reporting Patterns
Abstract: The global escalation of antimicrobial resistance (AMR) has emerged as a critical public health crisis, undermining decades of therapeutic advancements. While inappropriate prescribing and misuse of antibiotics are widely acknowledged contributors, the role of pharmaceutical promotion practices remains underexplored in influencing prescribing behaviors and downstream pharmacovigilance systems. This review critically examines how antibiotic promotion strategies – ranging from direct physician engagement to digital marketing – affect adverse drug reaction (ADR) …
Published in International Journal of Antibiotics · Vol. 3, Issue 2, 2026 · pp. 1–11 Read article
-
Formulation and Evaluation of Herbal Skin Cream
Abstract: Herbal cosmetics have gained significant attention in recent years due to increasing consumer preference for natural and safe skincare products. Herbal skin creams are semisolid formulations enriched with plant-derived ingredients that provide therapeutic as well as cosmetic benefits. These formulations are designed to enhance skin health by utilizing bioactive phytoconstituents such as flavonoids, alkaloids, tannins, essential oils, and vitamins. Herbal creams are generally prepared using oil-in-water (O/W) or water-in-oil (W/O) …
Published in Recent Trends in Cosmetics · Vol. 3, Issue 2, 2026 · pp. 20–32 Read article
-
Biopolymer-Based 3D Composite Scaffolds for Bone Tissue Engineering: Photothermal-Responsive Systems with Controlled Pt (IV) Prodrug Release
Abstract: Biopolymer-based composite scaffolds have attracted significant attention as multifunctional platforms at the intersection of polymer science, regenerative medicine, and cancer nanotherapy. In this study, a dual-functional scaffold was developed for simultaneous osteosarcoma treatment and bone regeneration using poly (L-lactic acid) (PLLA) reinforced with bioactive glass (BG) and integrated with a glutathione-responsive platinum (IV) prodrug system (PDA@Pt). To improve interfacial adhesion, photothermal conversion efficiency, and tumor-specific activation, the Pt (IV) prodrug …
Published in Journal of Polymer & Composites · Vol. 14, Issue 3, 2026 · pp. 351–361 Read article
-
Polymers and Composites in the Design and Construction of Unmanned Aerial Vehicles: A Comprehensive Technical Review
Abstract: The emergence of Unmanned Aerial Vehicles (UAVs) over the last few years has mostly been made possible by breakthroughs in material science. This review is concerned with an overview of some of the polymers and composites that are being commonly used in drone manufacturing in recent times, especially in relation to the influence of material choice on drone performance and capability. It sheds light on the drastic change in the …
Published in Journal of Polymer & Composites · Vol. 14, Issue 3, 2026 · pp. 874–882 Read article
-
Dynamic Vibration and Damping Analysis of Sustainable Nano-Reinforced Polymer Composite Elements for Vehicle Suspension Applications
Abstract: This paper presents an analytical investigation into the dynamic vibration characteristics of nano-reinforced polymer composite elements intended for vehicle suspension applications. A single-degree-of-freedom (SDOF) quarter-car model is employed to derive fundamental expressions for natural frequency, damping ratio, logarithmic decrement, and displacement transmissibility. The primary contribution lies in establishing explicit analytical linkages between material-level viscoelastic properties specifically storage modulus and loss modulus and system-level suspension parameters including stiffness and damping coefficients. …
Published in Journal of Polymer & Composites · Vol. 14, Issue 3, 2026 · pp. 561–570 Read article
-
Everlasting Life Achieved Through Technology in AI
Abstract: The concept of immortality Life is a philosophical idea that states life is limitless and does not stop with death, it exists infinitely. In our Sanskrit scriptures and Santana dharma teach us that there is a life of beginning and an end, which are referred to as birth and death but our souls do not perish, instead, they switch bodies. In this scenario, our memories have evaporated to protect our …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 4, Issue 1, 2026 Read article
-
Thermo-hydraulic Performance of Annular-Finned Double-Pipe Heat Exchanger: Numerical and Experimental Investigation of Metallic and Polymer Composite Tube Wall Materials
Abstract: Double-pipe heat exchangers are central to the process industries — dependable, easily maintained, and straightforward to fabricate. Their conventional form relies on metallic tube materials, most often copper or stainless steel. Both metals conduct heat well, but they are dense, prone to corrosion in aggressive service environments, and increasingly at odds with the light-weighting goals that drive modern system design. Fibre-reinforced polymer composites, epoxy-based materials, and thermally enhanced thermoplastics such …
Published in Journal of Polymer & Composites · Vol. 14, Issue 3, 2026 · pp. 891–909 Read article