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92 articles for “toxicological effects”
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Computational Exploration of Bhrijraj-derived Phytochemicals as Potential Anti-inflammatory Agents: A Molecular Docking Study with Cyclooxygenase-II Complex
Abstract: The molecular docking analysis was meticulously conducted using state-of-the-art computational tools, notably Chimera and Python. These tools were employed to unravel the complex interactions between the identified phytochemicals from Bhrijraj and the target protein, COX-II. The 3D structures of the phytochemicals were prepared with precision using ChemSketch, ensuring accuracy in the subsequent molecular docking simulations. This rigorous approach enhances the reliability and validity of the findings. This research aims to …
Published in Research and Reviews : Journal of Computational Biology · Vol. 13, Issue 1, 2024 · pp. 31–37 Read article
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Synthesis and Characterization of TiO2 1% SiO2 of Crystal and its Bacterial Applications
Abstract: Three-dimensional (3D) TiO2 Anatase and Rutile structures have attracted much attention due to their optical properties. However, the large band gap of (3.2 eV) results in the fact that anatase TiO2 can act as photo catalyst and be excited by UV light, which only accounts for 3–5% of the solar energy. On considering that nobel metallatic nanomaterials can harvest visible light, in this paper, TiO2 and SiO2 nanocrystals with rod …
Published in Research and Reviews: A Journal of Toxicology · Vol. 10, Issue 1, 2020 · pp. 47–58 Read article
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Thymoquinone Induces Epigenetic Modulation in ROS Dependent Manner
Abstract: Traditional drugs have the ability to treat broad range of diseases by modulating the signaling pathwaysof inflammatory diseases and cancer. Epigenetic modulation is also one of the mechanisms already established as a process of action. Histone deacetylase (HDAC) inhibition leads to changes in gene expression promoting cell death. Thymoquinone (TQ), a bioactive compound from Nigella sativa seeds has shown to have an antineoplastic effect in many cancers. Here we have …
Published in Research and Reviews: A Journal of Toxicology · Vol. 7, Issue 1, 2017 · pp. 32–39 Read article
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Toxicokinetics of Herbicide Residues in Green Forages: Implications for Fertility, Health, and Welfare of Dairy Cows
Abstract: Herbicide residues in green roughages have emerged as a significant concern in dairy production due to their potential toxicokinetic interactions and detrimental effects on reproductive health. While herbicides are widely used to control weeds and enhance fodder yield, their persistence in forage poses a latent risk to dairy cattle fertility. This review explores the absorption, distribution, metabolism, and excretion of herbicide residues in dairy cows, emphasizing their bioaccumulation and systemic …
Published in Research and Reviews : Journal of Dairy Science and Technology · Vol. 14, Issue 3, 2025 · pp. 48–64 Read article
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Toxicity Evaluation of a Few PAHs on a Local Freshwater Fish—Rasbora daniconius
Abstract: Polycyclic Aromatic Hydrocarbons (PAHs) have become ubiquitous pollutants of water resulting mainly from petroleum products. These are absorbed into the living systems and converted into secondary metabolites which show bioaccumulation in the living systems and have several deleterious effects on them. The present study attempts to evaluate toxicity of two such PAHs— Naphthalene and Anthracene—on the freshwater fish, Rasbora daniconius, using pure PAHs dissolved in dichloromethane. LC50 values were seen …
Published in Research and Reviews: A Journal of Toxicology · Vol. 10, Issue 1, 2020 · pp. 42–46 Read article
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A Brief Review of the Noxious Weed: Parthenium hysterophorus Linn.
Abstract: Every day we consume leafy vegetables in our meals, many of them are domesticated and few are wild ones. The weeds which are wild are nonedible and give an adverse effect on our health. Parthenium hysterophorus—a very common weed in India—is considered noxious and produce allergic respiratory problems, contact dermatitis, mutagenicity in human and livestock. Many of times it was mistakenly collected with the domesticated vegetables. It contains phenolic compounds …
Published in Research and Reviews: A Journal of Health Professions · Vol. 8, Issue 2, 2018 · pp. 1–7 Read article
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Effects of the Embryonic Bisphenol an Exposure on The Postnatal Development, Learning and Memory of Rat Offspring: Fundamental Study
Abstract: We studied the morphologic changes in some organs and changes of learning and memory of the rat offspring after the embryonic bisphenol A exposure. Background: Bisphenol A, widely used as polycarbonate plastics material to manufacture food packaging, toys, glasses, computers, kitchen utensils and medical instruments, is one of the most common endocrine-disrupting chemicals. It is demonstrated that bisphenol A may be mingled with foodstuff and beverage from package and receptacle. …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 13, Issue 2, 2024 · pp. 58–63 Read article
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Exposure of Nanoparticle Leads to Health Hazards
Abstract: Nanotechnology is a technique used for the production of materials of the nanoscale level. This is a new development in technology which usually entails some hazards as well as advantage to society. Thus nanomaterials are well known for their various beneficial uses in the medicines, engineering, computer, etc., in spite of that it is associated with many hazards related to human health. The exposure of nanomaterials through dermal contact, inhalation, …
Published in Research and Reviews: A Journal of Toxicology · Vol. 9, Issue 3, 2019 · pp. 7–18 Read article
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Arsenic Induced Cytotoxicity Study Against Human Epithelial Carcinoma (HeLa) Cell
Abstract: The present investigation was undertaken to find out the cytotoxic effects of various amounts of arsenic exposure to human epithelial carcinoma (HeLa) cell. Cells were treated with a final concentration (0, 10, 20, 30, 40 and 50 µg/l) of arsenite in 5 ml MEM for 24 h where 0 concentration was considered as control. Cell viability was determined by the trypan blue (TB) exclusion test using hematocytometer and automated BIO-RAD …
Published in Research and Reviews: A Journal of Toxicology · Vol. 5, Issue 1, 2015 · pp. 1–8 Read article
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The Alarming Impact of Microplastics on the Reproductive System of Fish
Abstract: Environmental contaminants that are biologically active significantly affect ecosystems, animals, and human health. Plastic pollution has drawn international attention for its detrimental effect on the environment and biodiversity health. The aquatic ecology of our planet is full of microplastics. Regular, extensive use of nonbiodegradable polymers required several years for them to break down. Over the course of those years, it discharged tiny particles of 100 nm or less. Due to …
Published in Research and Reviews : Journal of Veterinary Science and Technology · Vol. 13, Issue 2, 2024 · pp. 8–13 Read article
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Effects of Sub Chronic Dermal Exposure of Gasoline Blended with Varying Concentration of Benzene on Hepatic Mixed Function Oxidases in Rats
Abstract: Interaction of chemicals in a mixture, their biotransformation and adverse impact, if any, on environment and workroom atmosphere needs to be evaluated to identify the nature of potential toxic effects elicited by constituent chemical(s) in a mixture. The nature of chemical interaction(s) through which an individual chemical in a mixture undergoes metabolism and/or biotransformation in the target tissue could be helpful in evaluation of its toxic potential. Gasoline is a …
Published in Research and Reviews: A Journal of Toxicology · Vol. 3, Issue 1, 2013 · pp. 1–5 Read article
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Pattern of Poisoning, Management and Antidote Availability in St. Paulo’s Specialized Hospital Addis Ababa, Ethiopia
Abstract: Poisoning is the contact with a substance that results in toxicity. It can be deliberate or accidental. Antidotes are substances opposing the harmful effect of poisons and are cornerstones in the management of poisoning. Availability of antidotes highly affects the effective poisoning management. To assess the poisoning management in relation to an antidote availability. A retrospective study was used to assess the practice of poisoning management and antidote availability in …
Published in Research and Reviews: A Journal of Toxicology · Vol. 5, Issue 3, 2015 · pp. 8–12 Read article