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208 articles for “significance in biology”
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Glitches in the Implementation of Bioinformatics in Medical Settings: A Comprehensive Review
Abstract: Bioinformatics is a dynamic field at the intersection of biology, computer science, and information technology, offering new possibilities in medicine by enabling a deeper understanding of genomics, molecular biology, and personalized treatment approaches. Its integration into healthcare could greatly enhance diagnostics, enable tailored treatments for individuals, and facilitate the analysis of large biological datasets. However, despite its potential, several barriers impede its successful implementation in clinical settings. These include technical …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 11, Issue 3, 2024 · pp. 1–6 Read article
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Exploring the Thyroid Gland Physiology in Relation to Thyroid Hormones: An Overview through the Lens of 3D Computational Biology
Abstract: The endocrine system plays a pivotal role in orchestrating and sustaining diverse physiological functions by manufacturing and releasing hormones, which function as vital chemical messengers within the body. Among the prominent endocrine glands, the thyroid gland holds a central position. Situated in the lower part of the neck, this gland adopts a butterfly-shaped structure. Its significance lies in the synthesis of three key hormones: thyroxine (T4), tri-iodothyronine (T3), and calcitonin.The …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 11, Issue 1, 2024 · pp. 46–54 Read article
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Monoclonal Antibodies in Next Generation Animal Nutrition: Mapping Nutrient Immune Interaction Networks in Livestock Systems
Abstract: Sustainable livestock production is increasingly constrained by disease pressure, antimicrobial resistance, and declining feed efficiency under intensifying environmental stressors. Conventional nutritional strategies, while essential, remain insufficient to precisely regulate immune function and metabolic resilience. This review explores the emerging role of Monoclonal antibodies as advanced biologics in next generation animal nutrition, with a focus on mapping nutrient immune interaction networks in livestock systems. It synthesizes current knowledge on how nutrients …
Published in International Journal of Molecular Biotechnological Research · Vol. 4, Issue 1, 2026 Read article
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Entomo-Analytics: Insect Behavioral Intelligence for Climate-Smart Environmental Monitoring Systems
Abstract: Rapid environmental change driven by climate variability, urbanization, and ecological degradation has intensified the need for innovative monitoring systems capable of providing real-time ecological intelligence. Traditional environmental monitoring methods often rely on satellite imaging and stationary sensors, which may lack fine-scale biological sensitivity. In contrast, insects—due to their abundance, ecological diversity, and rapid responsiveness to environmental shifts—offer a powerful yet underutilized source of bio-sensing data. This paper introduces the concept …
Published in Research and Reviews : Journal of Crop science and Technology · Vol. 15, Issue 2, 2026 · pp. 17–26 Read article
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Insilico Structural Analysis and Homology Modeling of Crustin Protein from Fiddler Crab Species
Abstract: In terms of biomass and ecological or economic importance, the crustacea are the largest, most noticeable, and possibly, the most significance group of marine or aquatic arthropods. Because of their enormous commercial value and the necessity to prevent disease outbreaks in the shellfish aquaculture industry, decapods are the experimental animals of choice for practically all biological studies involving immune responses. Antimicrobial host-defense peptides (AMPs) are major components of metazoan immunity, …
Published in International Journal of Cheminformatics · Vol. 1, Issue 1, 2023 · pp. 1–7 Read article
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Agro- residue Pretreatment Tools and Techniques: A Detailed review
Abstract: This review examines the significance of biomass pre-treatment in facilitating efficient biofuel production from lignocellulosic materials. Different methods of pre-treatment, such as acid, alkaline, liquid hot water, ionic liquids, organosolv, ozonolysis, wet oxidation, steam explosion, ammonia fiber explosion (AFEX), carbon dioxide explosion, and biological pretreatment, are examined in terms of their underlying principles, benefits, and drawbacks. Acid pretreatment effectively hydrolyzes hemicellulose but suffers from equipment corrosion and high operational costs, …
Published in Research & Reviews : Journal of Botany · Vol. 13, Issue 1, 2024 · pp. 22–31 Read article
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Light-Dark Cycle Disruption in Hypothalamus Tissue of Mus Musculus Causes Change in the Expression of Gm45928 Gene
Abstract: The majority of organisms on earth display consistent 24-hour rhythms in their physiology and behavior due to circadian biology. Light and dark cycles play a key role in setting our internal body clock, which controls things like our sleep patterns, hormone levels, body temperature, and metabolism. The disruption of the light-dark cycle has significant effects on the molecular and behavioral rhythms of the circadian clock of hypothalamus. Gm45928 is a …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 3, Issue 1, 2025 · pp. 32–46 Read article
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A Study on Automatic Feedback Control by Image Processing for Mixing Solutions in a Microfluidic Device
Abstract: Precise and rapid mixing of chemical and biological reagents is a critical yet challenging aspect of microfluidic systems, often limited by laminar flow conditions and the need for manual or pre- programmed interventions. Existing mixing strategies frequently lack real-time adaptability and closed-loop control, hindering reproducibility and the execution of complex reaction protocols. This work presents an innovative automatic feedback control system utilizing the study on real- time image processing to …
Published in International Journal of Advanced Control and System Engineering · Vol. 3, Issue 2, 2025 · pp. 32–41 Read article
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Measurement of Urbanization in India: An Empirical Study Through Degree and Rate of Urbanization
Abstract: Urbanization is a progressive concentration of people in urban areas. Quantifying urbanization is a very challenging task. There are numerous demographic dimensions that can be used to quantify the urbanization process, among which the degree of urbanization and rate of urbanization are applied. Goal: Using Indian Census data from 1901 to 2011, this paper attempts to quantify the extent and pace of urbanization in India. The study is descriptive in …
Published in OmniScience: A Multi-disciplinary Journal · Vol. 14, Issue 1, 2024 · pp. 80–85 Read article
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A Study to Evaluate Mothers’ Perceptions and the Effectiveness of an Awareness Program Aimed at Enhancing Knowledge About Behavioral Issues in Primary School Children Within a Specific Community in Haldwani, Uttarakhand
Abstract: Background: Behavior is perceived in society as how an individual presents themselves in various situations. As a child grows, their development encompasses biological, psychological, and emotional changes that occur from birth. The parent-child relationship also evolves through daily, reciprocal interactions in different relational domains, such as attachment and authority, which lay the foundation for future interactions. These exchanges can significantly influence a child’s development across various areas, including emotional, physical, …
Published in International Journal of Community Health Nursing And Practices · Vol. 2, Issue 2, 2024 · pp. 9–13 Read article
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Thermally Adaptive Bio-Inspired VLSI Interconnect Model for Next-Generation Embedded Systems
Abstract: The increasing complexity of next-generation embedded systems has intensified the challenges associated with power dissipation, thermal instability, signal integrity, and interconnect reliability in Very Large- Scale Integration (VLSI) architectures. This research proposes a thermally adaptive bio-inspired VLSI interconnect model designed to enhance communication efficiency and thermal resilience in advanced embedded platforms. The proposed model integrates bio-inspired adaptive routing principles with dynamic thermal-aware interconnect management to optimize data transmission under varying …
Published in Journal of VLSI Design Tools and Technology · Vol. 16, Issue 2, 2026 Read article
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Clay–Polymer Nanocomposites: An Efficient Adsorbent for Waste Water Treatment
Abstract: Despite the abundance of water sources, the globe today lacks potable water because to pollution. Pollutants can be removed from water using a variety of technologies, but adsorption is considered the most simple, effective, economical, and ecologically beneficial method. The class of adsorbents known as clay–polymer nanocomposite (CPN) adsorbents is one that is now gaining popularity. By adsorbing and flocculating inorganic and organic micropollutants from water, CPNs efficiently cleanse water. …
Published in Journal of Polymer & Composites · Vol. 12, Issue 5, 2024 · pp. 111–118 Read article
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Natural and synthetic pesticide and their effect on life
Abstract: Natural and synthetic pesticides both play roles in pest control but differ significantly in their impact on life and the environment. Natural pesticides, often derived from plants and microorganisms, are biodegradable, eco-friendly, and generally exhibit lower toxicity to non-target organisms and humans. Synthetic pesticides, while highly effective in pest control and used extensively in conventional agriculture, tend to have greater toxicity, persist longer in the environment, and pose more significant …
Published in Journal of Modern Chemistry & Chemical Technology · Vol. 16, Issue 3, 2025 · pp. 8–13 Read article
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Electrochemical Biosensors for Disease Diagnostics
Abstract: Electrochemical biosensors have emerged as one of the most promising tools for disease diagnosis because they combine high sensitivity, rapid response, portability, and low cost in a single analytical platform. In recent years, growing interest in early disease detection has pushed researchers to develop biosensors that can detect clinically important biomarkers in blood, saliva, urine, sweat, and other biological fluids. These sensors work through the interaction between a biological recognition …
Published in Nano Trends – A Journal of Nano Technology & Its Applications · Vol. 28, Issue 2, 2025 Read article
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In Vivo Biocompatibility and Interfacial Stability of Thermoplastic Polyurethanes and Nanofilled Resin Composites: A Bioanalytical Study of Polymer-Host Interactions Under Dynamic Loading
Abstract: The widespread application of thermoplastic polyurethanes (TPU) and nanofilled resin composites in biomedical devices requires rigorous assessment of their biocompatibility under mechanical stress. While nanofilled composites utilize filler particles (<100 nm) to enhance surface properties and wear resistance, the biological response to these materials in a hydrolytic, enzymatic environment remains a critical area of investigation. Objective: To analyze the in vivo bio-molecular response at the interface of TPU aligners and …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 1112–1119 Read article
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AI Application in the Creation of Medications for COPD
Abstract: The crippling lung condition known as chronic obstructive pulmonary disease (COPD) is typified by a continuous restriction of airflow, which results in increased respiratory dysfunction and a reduced quality of life. The rising incidence of COPD worldwide emphasizes the pressing need for innovative pharmaceutical approaches to address the illness. Even though COPD care has advanced significantly, most current medications concentrate on symptom relief rather than disease change. This gap in …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 12, Issue 2, 2025 · pp. 01–05 Read article
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Nutrient Sensing and Microbiota Crosstalk: Driving Determinants Shaping Metabolic Stability and Adaptive Physiology for Animal Health
Abstract: Nutrient sensing is a fundamental cellular process that enables animals to adapt to fluctuating dietary inputs while maintaining metabolic homeostasis and health. Recent advances reveal that the gut microbiota functions as an active metabolic partner, producing bioactive metabolites that directly influence host nutrient-sensing pathways and downstream cellular responses. This review synthesizes current knowledge on the integration of key signalling networks, including adenosine monophosphate activated protein kinase (AMPK), mechanistic target of …
Published in International Journal of Molecular Biotechnological Research · Vol. 4, Issue 2, 2026 Read article
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Advancing Asthma Management: The Synergy of Systems Biology, Artificial Intelligence, and Next-Generation Therapeutics
Abstract: Asthma is an inflammatory disorder of the respiratory tract that is chronic and heterogeneous in nature and has various effects on millions of people. Being a chronic inflammatory disease, asthma remains incurable and the major conventional treatments offer limited success due to the mask nature of its pathophysiology. Systems biology/(AI), and next-generation has greatly enhanced knowledge and the management of asthma. The approaches based on gene, transcript, protein, and metabolite …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 14, Issue 2, 2024 · pp. 1–12 Read article
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The Art of Drug Design and Process Chemistry
Abstract: The creation of safe and efficient medications depends heavily on the art of drug design and process chemistry. This multidisciplinary discipline designs and optimizes drug candidates for therapeutic uses by fusing the concepts of biology, chemistry, and engineering. Researchers can develop compounds with pharmacological activity by using logical drug design techniques if they have a thorough understanding of the molecular targets implicated in disease pathways. By making it easier to …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 3, Issue 1, 2025 · pp. 1–10 Read article
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Innovations in Targeted Drug Discovery for Personalized Medicine
Abstract: Personalized medicine is revolutionizing modern healthcare by custoizing treatment plans to match an individual’s genetic makeup, protein expression, and metabomlic characteristics. Also referred to as precision medicine, this approach seeks to improve therapeutic outcomes, reduce adverse effects, and make efficient use of healthcare resources. The incorporation of various omics technologies—including genomics, proteomics, transcriptomics, metabolomics, and epigenomics—has greatly advanced our ability to understand disease biology and molecular variations specific to each …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 12, Issue 3, 2025 · pp. 19–41 Read article