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118 articles for “gene regulation”
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STRUCTURAL–EPIGENOMIC ATLAS: CNV/SV- DRIVEN PROGNOSTIC REFINEMENT ACROSS CANCERS
Abstract: Structural genomic alterations, including copy number variations (CNVs) and structural variants (SVs), play a central role in cancer initiation and progression. These alterations extend beyond gene dosage effects and interact dynamically with epigenomic mechanisms such as DNA methylation, histone modifications, and three-dimensional chromatin organization. Recent pan-cancer studies have demonstrated that CNV burden and SV signatures reflect key oncogenic processes including chromothripsis, homologous recombination deficiency, enhancer hijacking, and extrachromosomal DNA (ecDNA) …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 4, Issue 1, 2026 Read article
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Digital Literacy: A Faculty-Based Comparative Study of Research Scholars at the University of Rajasthan
Abstract: This study explored how much “research scholars in the department of Social Science and Arts of the University of Rajasthan, Jaipur”, understand and use digital technologies. The findings based on 84 questionnaires show that scholars of the Social Science faculty have a relatively high digital literacy compared to those in the Arts faculty. Most of the respondents indicated that they were skilled in using open-access sources. However, about a quarter …
Published in International Journal of Behavioral Sciences · Vol. 3, Issue 2, 2026 · pp. 34–43 Read article
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An Overview on Energy Harvesting Using Piezoelectric Material for Wi-Fi Systems
Abstract: The rapid proliferation of wireless-networked devices has intensified the demand for sustainable, maintenance-free power sources that can keep small-scale Wi-Fi modules operational in hard-to-reach or infrastructure-limited environments. This study investigates the feasibility of harvesting ambient mechanical energy using piezoelectric transduction technology and directly feeding the harvested power to a low-power Wi-Fi communication subsystem. A compact energy-harvesting module was engineered from lead-zirconate-titanate (PZT) cantilevers with resonant frequencies tuned to the dominant …
Published in International Journal of Electro-Mechanics and Material Behaviour · Vol. 4, Issue 1, 2026 · pp. 56–63 Read article
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Nutraceutics: Opening the Debate for a Framework for the Safety and Efficacy of Nutraceuticals Formulations
Abstract: As of right now, there is no precise definition for nutraceuticals that distinguishes them from other food-based categories such herbal products, dietary supplements, pre- and probiotics, functional foods, and fortified foods. Several studies have shed light on the possible mechanisms of action of pharmaceutically active ingredients in food, emphasizing their ability to improve health, lower the risk of disease, and promote general wellbeing. However, Nutraceuticals confront difficulties in substantiating safety …
Published in Recent Trends in Infectious Diseases · Vol. 1, Issue 1, 2024 · pp. 27–33 Read article
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The Next Era of Solid-State Innovation: Beyond Silicon
Abstract: The semiconductor industry is getting close to the physical and economic boundaries of silicon-based technology. A new era of solid-state innovation is beginning. Beyond Silicon: The Next Era of Solid-State Innovation looks at the materials, device layouts, and manufacturing methods that are about to change the way electronics and energy work. The article talks about improvements in wide- and ultra-wide-bandgap semiconductors, two- dimensional materials, and quantum and neuromorphic systems that …
Published in International Journal of Solid State Innovations & Research · Vol. 3, Issue 2, 2025 · pp. 19–23 Read article
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Antimicrobial Resistance and AI-Based Strategies for Rapid Pathogen Detection
Abstract: Antimicrobial resistance (AMR) has become a major global health threat, significantly reducing the effectiveness of antimicrobial therapies and increasing the burden of infectious diseases worldwide. The rapid emergence of multidrug-resistant pathogens has created an urgent need for faster, more accurate, and scalable diagnostic approaches to support timely treatment and effective infection control. Artificial intelligence (AI) has emerged as a promising technology capable of transforming pathogen detection and AMR surveillance through …
Published in Recent Trends in Infectious Diseases · Vol. 3, Issue 2, 2026 · pp. 26–36 Read article
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Prediction of Molecular Targets for Anthraquinone and Its Analogs for Treatment of Good Pasteur Syndrome
Abstract: Objective: In order to find prospective molecular targets for the treatment of Good Pasteur Syndrome (GPS), a rare autoimmune disease that affects the kidneys and other organs, computational methods and network pharmacology were applied in this work. The goal of the study is to identify particular human proteins that might interact with anthraquinone and its analogues as well as to uncover potential mechanisms of action by which these drugs might …
Published in International Journal of Bioinformatics and Computational Biology Read article
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Anti-hyperglycemia Effects of Plant Secondary Metabolites Towards PKA/CREB Pathway Activation in Diabesity
Abstract: Objective: Diabesity, the amalgamation of diabetes and obesity, presents a significant global health challenge. This research carefully examines how plant secondary metabolites influence glucose regulation in diabetes using the PKA/CREB pathway, paying particular attention to diabesity—the combination of diabetes and obesity. Understanding the complex ways in which these metabolites affect metabolic health will help to identify new treatment approaches for managing diabetes and its associated problems. By conducting a thorough …
Published in International Journal of Biochemistry and Biomolecule Research · Vol. 2, Issue 1, 2024 · pp. 33–50 Read article
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Invisible Shield: How the Atmosphere Keeps Us Safe from Space
Abstract: Invisible Shield shows us how incredible Earth's atmosphere is at keeping us safe from space threats. The atmosphere is a moving, multi-layered shield that keeps us safe from harmful solar radiation and burns up meteoroids before they impact the ground. This page discusses about the science behind climate control, magnetic interactions, and atmospheric chemistry. It depicts how various systems work together to keep the ground stable. It also talks about …
Published in International Journal of Atmosphere · Vol. 2, Issue 2, 2025 · pp. 39–49 Read article
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Artificial Intelligence in Early Diagnosis and Personalized Treatment of Alzheimer’s Disease
Abstract: Artificial intelligence (AI) has become a disruptive technology in the medical care industry, with potential solutions to early diagnosis and customized treatment of Alzheimer’s disease (AD), a progressive neurodegenerative disease and the most prevalent cause of dementia globally. Conventional diagnostic techniques, such as cognitive, neuroimaging and biomarker techniques, are usually limited in the ability to detect disease at its most susceptible stage when treatment interventions are most effective. The recent …
Published in International Journal of Brain Sciences · Vol. 3, Issue 2, 2026 · pp. 15–27 Read article
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An analytical study on effectiveness of E-learning
Abstract: E-learning has increasingly established itself as a vital mode of education in the digital era, where information is widely accessible. This study provides an analytical perspective on the effectiveness of e-learning practices across diverse academic and professional settings. Drawing upon a broad body of literature, the paper examines how e-learning influences learner engagement, knowledge retention, skill development, and overall academic performance. Key factors shaping its effectiveness—such as instructional design, technological …
Published in International Journal of Education Sciences · Vol. 3, Issue 1, 2026 · pp. 108–115 Read article
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In Silico Molecular Docking of Indigofera tinctoria Phytocompounds to Target EGFR/ERK and FGFR/FGF Pathway Proteins Involved in Prostate Cancer
Abstract: Objective: Prostate cancer being the second major cause of cancer-related deaths in males, affects the small walnut-shaped gland below the bladder called the prostate gland. The epidermal growth factor protein (EGFR), cascade protein (ERK), and fibroblast growth factor proteins (FGFR and FGF) are involved in the different signaling pathways that lead to the formation of different products, that are responsible for the progression of cancer and thus can be considered …
Published in International Journal of Molecular Biotechnological Research · Vol. 1, Issue 1, 2023 · pp. 34–56 Read article
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Stem Cell Therapy: Advancements, Applications, and Future Prospects in Regenerative Medicine
Abstract: Stem cell therapy has come up as a revolutionary technique in regenerative medicine living up to the promise in treating numerous diseases and injuries. The latest discoveries made in the field of stem cell research such as the introduction of gene editing technology like CRISPR and the creation of the 3D bioprinting process have increased the accuracy and efficacy of stem cell-based therapies. Examples include cardiac regeneration and repair of …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 4, Issue 1, 2026 Read article
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Automatic Bluetooth Controlled Shutter System Using Microcontroller and Mobile Application
Abstract: Automation has become an essential part of modern engineering system. Manual shutter systems used in shops, garages, and industries require physical effort and time. To overcome these limitations, wireless control systems using Bluetooth technology have been developed. Bluetooth-based automation systems allow communication between smartphones and embedded systems. These systems are widely used due to their low cost, low power consumption, and ease of integration. This paper focuses on designing a …
Published in International Journal of Electronics Automation · Vol. 4, Issue 2, 2026 Read article
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Cosmeceuticals – The Reality Beyond Expectation
Abstract: Cosmeceuticals, a fusion of cosmetics & pharmaceuticals, have revolutionized the personal care industry. Beyond just being aesthetically pleasing, many products have therapeutic effects that address skin issues and enhance general wellbeing. This review explores the historical background, classification, types, and benefits of cosmeceuticals. The global market demand for cosmeceuticals is rising, driven by the desire for youthful and healthy appearances. However, the industry faces challenges, including variable efficacy, safety concerns, …
Published in Recent Trends in Cosmetics · Vol. 2, Issue 1, 2025 · pp. 44–54 Read article
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The Future of Robotics: A Review of AI-Enabled Robotics Research, Development, and Applications
Abstract: Robotics powered by artificial intelligence (AI) is transforming contemporary industries by empowering machines to learn, adapt, and operate on their own in intricate, changing contexts. The breadth and capabilities of automation have been greatly expanded by the convergence of AI technologies with robots, including machine learning, deep learning, computer vision, and natural language processing (NLP). With an emphasis on technological advancements, application areas, and research advances, this study examines current …
Published in International Journal of Robotics and Automation in Mechanics · Vol. 3, Issue 2, 2025 · pp. 33–38 Read article
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IoT-Based Real-Time Monitoring System for Temperature and Humidity Control in Pharmaceutical Manufacturing
Abstract: Environmental conditions, especially temperature and humidity, play a vital role in pharmaceutical manufacturing processes. Even minor fluctuations in these parameters can significantly influence the stability, potency, and overall effectiveness of drug formulations. In many cases, uncontrolled environmental variations may lead to chemical degradation, reduced shelf life, contamination risks, and substantial financial losses for manufacturers. Therefore, maintaining precise and consistent environmental conditions is essential to ensure product quality, regulatory compliance, and …
Published in International Journal of Mobile Computing Technology · Vol. 4, Issue 1, 2026 · pp. 32–37 Read article
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The Role of Artificial Intelligence and Machine Learning in Redefining Global Healthcare Systems and Advancing Medical Innovation
Abstract: Health Services are being revolutionized with AI and ML through improved accuracy, efficiency and accessibility in the delivery of health care. With AI and ML, it is now possible for health care professionals to assess varying amounts of complex clinical data in a relatively short amount of time, therefore, creating opportunities for early detection of disease, increasing the odds of accurate diagnosis, and improving the ability to make informed clinical …
Published in International Journal of Biomedical Innovations and Engineering · Vol. 4, Issue 1, 2026 · pp. 14–19 Read article
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Evaluating the Performance of Mobile Air Compressor Component of Radiator Unit using the Application of Reliability
Abstract: The application of reliability to monitor and predict the performance of mobile air compressor component of radiator unit was considered in this research. This study demonstrated some of the root causes of the radiator unit failure as effect of temperature and the nature of coolers used, because these two parameters cause corrosion, affect shortage on fluid level and in turn influence the internal heat generated by radiator unit of the …
Published in International Journal of Pollution: Prevention & Control · Vol. 1, Issue 1, 2023 · pp. 39–43 Read article
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Sliding Mode Controller-based Load Frequency Regulation for a Two-area Interrelated Power System
Abstract: This study presents the use of the sliding mode control approach for power systems load frequency regulation. A sliding mode load frequency controller is part of a two-area power system. Both reheat and non-reheat. These two regions each have a distribution of thermal turbines. Nonlinearities such as governor dead region and production rate limitations are included in the block diagram of a power plant model. Our control objective is to …
Published in International Journal of Advanced Control and System Engineering · Vol. 1, Issue 2, 2023 · pp. 8–13 Read article