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109 articles for “combination therapy”
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The Rising Burden of Heart Attacks: Causes, Trends, and Prevention Strategies
Abstract: Heart attacks, or myocardial infarctions, remain a leading cause of morbidity and mortality worldwide, with their incidence rising steadily across diverse populations. This review explores the increasing prevalence of heart attacks, emphasizing traditional risk factors, such as poor diet, physical inactivity, smoking, and medical conditions like hypertension, diabetes, and hyperlipidemia. It also highlights emerging risk factors, such as chronic infections, pollutants, substance abuse, and the lasting cardiovascular effects of COVID-19. …
Published in Research and Reviews : Journal of Surgery · Vol. 14, Issue 2, 2025 · pp. 1–11 Read article
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Ovarian Cancer: Understanding Risk Factors, Diagnosis, and Advances in Treatment
Abstract: Ovarian cancer is a leading cause of cancer-related mortality among women worldwide, often diagnosed at advanced stages due to its subtle early symptoms. Ovarian cancer develops due to a combination of factors, including genetics, environmental influences, and hormonal changes. This article explores the pathophysiology of ovarian cancer, highlighting the genetic mutations, such as BRCA1 and BRCA2, that contribute to its development. It also discusses current diagnostic methods, including imaging techniques …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 14, Issue 2, 2025 Read article
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Management of Thermal Burns over Breast – Our Experience
Abstract: The intricate challenge of restoring normal anatomy with minimal deformity in burns over the breast region has prompted the development of innovative tissue regeneration approaches. Addressing the complex nature of challenging wound patterns necessitates a multidisciplinary team with diverse expertise. In our concerted effort, we have successfully integrated advanced reconstructive techniques with regenerative medicine modalities to enhance outcomes in the intricate realm of complex breast reconstruction post-thermal burns. Our approach …
Published in International Journal of Biomedical Innovations and Engineering · Vol. 1, Issue 2, 2023 · pp. 1–8 Read article
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Biomarkers in Cancer Research: Discovery and Future Directions
Abstract: Biomarkers have transformed the study of cancer, providing critical information regarding prognosis and therapy response and promoting earlier diagnosis. This paper discusses the different parts of cancer biomarkers, starting with their description, classification, and major types, which are the groundwork for understanding their clinical role. The discussion on the development and validation process of biomarkers is then undertaken, focusing on state-of-the-art techniques and the importance of ensuring accuracy and reproducibility. …
Published in Trends in Drug Delivery · Vol. 12, Issue 1, 2025 · pp. 22–26 Read article
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Polymer Chemistry in Shoulder Orthotics
Abstract: The design of effective shoulder orthotic devices has increasingly made use of polymeric materials because of their versatility, durability, and biocompatibility. This review illustrates polymer chemistry role in constructing an orthotic device for shoulder subluxation, which is a commonly occurring post stroke or injury condition. Proprietary design elements such as polypropylene are rigid yet moldable which help in anatomical formulating for joint stabilization. On the other hand, rubber elastomers, medicinal …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 21–28 Read article
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Polymeric Actions to Make Recycled Aggregate of Concrete Improved
Abstract: Recycling construction materials of concrete, steel, and steel scraps is an essential technique to promote sustainable material flow. The restricted reuse of recycled concrete aggregate (RCA) can be justified, even in part, by the impact on strength and durability of new RCA-based concrete, instead of natural aggregates. Various research has been conducted on improving RCA effectiveness, in particular resistance and water absorption to disintegration. Application of polymer-dependent therapy was used …
Published in Journal of Polymer & Composites Read article
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Impact of Music on Reducing Stress: A Case Study on Reducing Stress on Female Students of Universities
Abstract: This case study explores the effects of music as a stress reduction tool for college students. Stress is a prevalent issue affecting the physical and mental well-being of students, with potential long-term consequences for their academic performance and overall health. This study employs a mixed-methods approach, combining surveys, and interviews to gather comprehensive data. A total of 100 students participated in our survey. The research focuses on assessing the relationship …
Published in International Journal of Mobile Computing Technology · Vol. 1, Issue 2, 2023 · pp. 26–30 Read article
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Understanding Leukemogenesis: Challenges and Advancements in Diagnostic Approaches
Abstract: Leukaemia development, or leukemogenesis, is a multifactorial process driven by a complex interplay of environmental, genetic, and epigenetic factors. Despite substantial advancements in technology and medicine, which have enhanced our understanding of the contributing factors, early and accurate diagnosis remains a major challenge due to the overlapping clinical features shared by the various leukaemia subtypes. This study explores the molecular and cellular mechanisms underlying leukemogenesis, while also addressing the difficulties …
Published in International Journal of Biomedical Innovations and Engineering · Vol. 3, Issue 1, 2025 · pp. 11–22 Read article
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Anti-hyperglycemia Effects of Plant Secondary Metabolites Towards PKA/CREB Pathway Activation in Diabesity
Abstract: Objective: Diabesity, the amalgamation of diabetes and obesity, presents a significant global health challenge. This research carefully examines how plant secondary metabolites influence glucose regulation in diabetes using the PKA/CREB pathway, paying particular attention to diabesity—the combination of diabetes and obesity. Understanding the complex ways in which these metabolites affect metabolic health will help to identify new treatment approaches for managing diabetes and its associated problems. By conducting a thorough …
Published in International Journal of Biochemistry and Biomolecule Research · Vol. 2, Issue 1, 2024 · pp. 33–50 Read article
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Wiskott-Aldrich Syndrome: A Comprehensive Guide
Abstract: Wiskott-Aldrich Syndrome (WAS) is an uncommon genetic disorder inherited through the X chromosome, marked by a combination of immune system deficiencies, eczema, and low platelet counts. This syndrome primarily affects males, leading to significant morbidity and mortality due to recurrent infections, bleeding complications, and autoimmune diseases. Mutations in the WAS gene disrupt the production of the Wiskott-Aldrich Syndrome protein (WASp), crucial for the functioning of immune cells and platelet formation. …
Published in Research and Reviews : A Journal of Immunology · Vol. 14, Issue 2, 2024 · pp. 39–46 Read article
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Nanotechnology In Herbal Medicine
Abstract: Herbal medicine has been widely used for centuries as a natural and holistic approach to health care. However, many herbal compounds face challenges such as low solubility, low bioavailability, instability, and the lack of targeted delivery, which affect their efficacy. The integration of nanotechnology into herbal medicine has emerged as a promising strategy to overcome these challenges and enhance the pharmacological potential of plant-derived compounds. Nanocarriers such as liposomes, solid …
Published in Nano Trends – A Journal of Nano Technology & Its Applications · Vol. 28, Issue 1, 2025 · pp. 50–69 Read article
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Development and Evaluation of a Novel Polyaniline/Polyvinyl Alcohol/Silver Nanocomposite for Antibacterial Applications: Synthesis and Characterization
Abstract: A novel nanocomposite made up of polyaniline, polyvinyl alcohol, and silver (PAL/PVA/Ag) was synthesized using the reduction of chemical technique in this study. Aniline was polymerized in situ with ammonium persulfate to create polyaniline (PAL), while Ag+ ions were employed to make an nanoparticle of Ag colloidal solution. The combination of Ag nanoparticles with the PAL/PVA composite resulted in the development of a new nanocomposite. Scanning electron microscopy (SEM) and …
Published in Journal of Polymer & Composites · Vol. 11, Issue 3, 2023 · pp. 39–47 Read article
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Review on Hair Cosmetics on Flaxseeds
Abstract: Worldwide cultivation of flaxseed (Linum usitatissimum), a significant medicinal oil seed crop, is practiced. Flaxseed belongs to the Linaceae family.Because of its biologically active components, which include lignans, dietary fiber, and alpha-linolenic acid, flaxseed has garnered interest as a functional food ingredient recently.Worldwide, Flaxseed is cultivated not only for its oil and fiber but also for its nutritional and potential therapeutic benefits. The dietary fiber present in flaxseed supports overall …
Published in Research and Reviews : A Journal of Ayurvedic Science, Yoga and Naturopathy · Vol. 12, Issue 2, 2025 · pp. 38–46 Read article
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Herbal Frontiers: The Role of Alternative Remedies in Combating Typhoid Fevers
Abstract: Typhoid fever, caused by Salmonella typhi, remains a major health challenge, particularly in developing regions where sanitation and healthcare resources are limited. With an estimated global incidence of 17 million cases annually, the disease poses a significant public health burden. The growing resistance to conventional antibiotics, such as fluoroquinolones and third-generation cephalosporins, exacerbates treatment challenges. This has spurred interest in alternative remedies, including herbal and homeopathic treatments.Herbal medicine offers a …
Published in Recent Trends in Infectious Diseases · Vol. 2, Issue 1, 2025 Read article
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The Therapeutic Potential of Nutraceutical in Diabetes Management: A Comprehensive Review
Abstract: Diabetes is a long-term and complex condition characterized by high blood sugar levels resulting from inadequate insulin production, ineffective insulin function, or a combination of both. Various nutraceuticals used in clinical settings have shown beneficial impacts on a range of biochemical and clinical markers related to diabetes. In many traditional medical systems, hypoglycemic agents derived from plants are used to treat, manage, and prevent diabetes mellitus. These plant extracts have …
Published in Emerging Trends in Metabolites · Vol. 2, Issue 1, 2025 · pp. 20–27 Read article
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Role of Polymeric Composites in Controlled Drug Release Systems
Abstract: In the realm of controlled drug release systems, polymeric composites have attracted a lot of interest as they possess several diverse characteristics that enable exact control of the drug delivery rate. This lowers adverse effects and increases the efficacy of treatment. Usually composed of biocompatible polymers combined with functional fillers like nanoparticles, ceramics, or hydrogels, these composites help to get the desired drug release patterns. Stable, biodegradable, and bioactive materials …
Published in Journal of Polymer & Composites · Vol. 13, Issue 4, 2025 · pp. 453–465 Read article
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Computational Simulations in Drug Discovery: Modeling Protein Folding and Drug Binding
Abstract: Computational simulations have become essential tools in drug discovery, offering unprecedented insights into molecular behavior at the atomic level. These simulations, particularly in the domains of protein folding and drug binding, allow for the exploration of complex biological systems that are often difficult to study experimentally. Protein folding, a critical aspect of drug discovery, involves the transition of a polypeptide chain from an unfolded to a biologically active structure. Understanding …
Published in Research and Reviews : Journal of Computational Biology · Vol. 14, Issue 1, 2025 · pp. 23–29 Read article
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Polymeric Emulsion Composite System Enriched with Eggshell-Derived Biominerals for Dermal Delivery
Abstract: This study describes the development and characterization of a sustainable polymeric water-in-oil (W/O) emulsion composite designed for dermal delivery and skin repair applications. The formulation was prepared using a lipid-rich biopolymeric matrix containing glyceryl stearate, beeswax, and plant-derived ingredients, which acted as the continuous phase for stabilizing and dispersing inorganic mineral fillers. Eggshell waste was utilized as a natural calcium source and combined with magnesium and zinc oxide to create …
Published in Journal of Polymer & Composites · Vol. 14, Issue 4, 2026 Read article
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Advances in Polymer Chemistry for Biomedical Applications: A Focus on Wearable Therapeutic Devices
Abstract: Polymer chemistry has significantly contributed to the evolution of biomedical materials, particularly in the development of wearable therapeutic devices. The combination of biocompatible polymers with advanced composite materials has led to the creation of flexible, durable, and patient-friendly medical support systems. These innovations have transformed healthcare by providing non-invasive and comfortable solutions for managing chronic pain and musculoskeletal disorders. Recent advancements in polymer chemistry have focused on three key areas: …
Published in Journal of Polymer & Composites · Vol. 13, Issue 5, 2025 · pp. 7–15 Read article
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Effective Homoeopathic Management of Allergic Rhinitis: A Case Series Utilizing Hepar Sulph 30 and Histamine 30 with Dietary Modifications
Abstract: Background: Allergic rhinitis (AR), means our immune system intruded by some allergens which is typically a harmless substance. These allergens are found in the air we breathe, in the food we eat, in the water and fluids we drink. These allergens are attacking on our immune system and the immune system responds to the allergens by releasing histamine and chemical mediators that cause symptoms in the nose, throat, eyes, ears, …
Published in Research & Reviews : A Journal of Unani, Siddha and Homeopathy · Vol. 11, Issue 2, 2024 · pp. 12–16 Read article