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100 articles for “chronic disease management”
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Integrating Counseling into ESRD Care: Addressing Mental Health to Enhance Patient Outcomes
Abstract: End-Stage Renal Disease (ESRD), also referred to as Chronic Kidney Disease Stage 5 (CKD-5), profoundly impacts patients' physical health as well as their emotional and psychological well-being. As individuals approach renal failure, they commonly encounter complex mental health challenges such as depression, anxiety, chronic stress, and a markedly diminished quality of life. This study underscores the critical importance of integrating emotional and mental health support into the care of ESRD …
Published in Research and Reviews: A Journal of Medicine · Vol. 15, Issue 3, 2025 Read article
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Concurrent Acute Fatty LIVER of Pregnancy, Acute Hepatitis, And Viral Meningitis in An Advanced Maternal Age Pregnancy a Rare Triple Presentation
Abstract: Background: Acute fatty liver of pregnancy (AFLP) is a sometimes lethal, but very seldom, chronic hepatic disease during late pregnancy. The presence of AFLP with other severe diseases raises the level of diagnostic and therapeutic complexity to a higher level. Case Presentation: We present the case of a 45 years old multigravita and 26 weeks of gestation with a distinct triad of AFLP, acute viral hepatitis (cytomegalovirus [CMV] and herpes …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 15, Issue 1, 2026 · pp. 7–11 Read article
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Environmental and Health Impacts of Rice Milling: A Case Study of Dinajpur Sadar Upazila, Bangladesh
Abstract: Rice milling plays a crucial role in Bangladesh's agricultural economy but contributes significantly to environmental pollution, affecting air, water, and soil quality, which in turn impacts public health and agricultural productivity. While prior studies have focused on immediate health effects like respiratory problems and reduced crop yields, they often overlook long-term consequences such as chronic diseases, soil degradation, and socio-economic impacts. Additionally, there is limited comparison between traditional and automated …
Published in International Journal of Climate Conditions · Vol. 2, Issue 1, 2025 · pp. 18–28 Read article
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Physicochemical Parameters for Water-Environment Quality Testing: A Review
Abstract: The increasing threat posed by contaminants in air, water, and soil is a pressing issue globally, exacerbated by population growth, industrialization, and agricultural practices. These factors contribute to significant water pollution, introducing harmful substances that compromise human health. Natural processes, such as weathering and soil leaching, alongside mining activities, further degrade water quality. Regular monitoring of drinking water is essential, as contaminated sources can lead to a variety of waterborne …
Published in International Journal of Pollution: Prevention & Control · Vol. 3, Issue 1, 2025 · pp. 08–12 Read article
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In Silico Screening and Molecular Docking of Cynodon dactylon phytochemicals against COPD-Associated Proteins
Abstract: Chronic Obstructive Pulmonary Disease or COPD is a pulmonary disease that obstructs airways and alveoli accompanied by respiratory issues like emphysema and bronchitis. This disease is caused mainly by inflammatory responses of the body to foreign particles that enter the respiratory path including tobacco smoke, air pollutants and irritants. The hallmark of COPD is excessive inflammation caused by imbalance in protease anti-protease activity. Proteases like elastase breakdown the ECM of …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 16, Issue 2, 2026 Read article
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A Prospective Observational Study of Prescription and Quality of Life: Gastroesophageal Reflux Disease in Territory Care Hospital
Abstract: Aims and objective: The main aim of the study is to know the quality of life in GERD patients and the management of GERD with the help of prescription patterns and patient counseling. Methodology: After receiving approval from Departmental Research Committee AIPBS with the reference no AIPBS/2021/4586/11 on dated 30 September 2021 and also approved from the Ethics Committee of Biomedical and Health Research, Adesh University with the reference no …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 14, Issue 3, 2024 · pp. 14–21 Read article
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In-Silico Docking of Rubia cordifolia Phytocompounds as Potential MMP-2 Inhibitors for Varicose Vein Management
Abstract: Varicose veins are one of the most common disorders, affecting the vein structure and function of lower limbs, yet there has been no absolute cure found yet. One of the underlying causes for worsening of the condition is the proteolytic activity of MMPs which are a group of enzymes that affect the extracellular matrix (ECM) surrounding the affected veins. Phytocompounds of Rubia cordifolia (Manjishta) were docked against the MMP-2 protein …
Published in International Journal of Biochemistry and Biomolecule Research · Vol. 3, Issue 2, 2025 · pp. 31–42 Read article
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Gut Microbiome Dysbiosis During Metabolic Disorders: Diabetes
Abstract: Understanding the intricate interplay between gut microbiome dysbiosis and diabetes is crucial due to the escalating prevalence and impact of diabetes mellitus globally. This comprehensive review examines the current understanding of this relationship, elucidating how alterations in the gut microbiome composition contribute to diabetes pathogenesis by influencing metabolic homeostasis, immune regulation, and insulin resistance. Dysregulation of gut microbial communities leads to shifts in diversity and abundance, exacerbating chronic low-grade inflammation …
Published in Emerging Trends in Metabolites · Vol. 1, Issue 2, 2024 · pp. 56–75 Read article
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Metabolic Syndrome in Psoriatic Patients: A Cross-Sectional Study
Abstract: Background: Psoriasis is a chronic immuno-inflammatory disease affecting the skin and joints. Studies have demonstrated an increased prevalence of conventional cardiovascular risk factors such as diabetes mellitus, hypertension, and metabolic syndrome in these patients. The aim of this study was to determine the association between psoriasis and metabolic syndrome. Material and Method: An observational cross-sectional study was carried out between November 2023 and October 2024, including participants with and without …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 15, Issue 1, 2026 · pp. 17–23 Read article
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Unraveling Ulcerogenesis: A Comprehensive Delve of Enteric & Nonenteric Ulcers
Abstract: Enteric ulcers present a multifaceted landscape encompassing both peptic and non-peptic varieties, demanding a thorough exploration of their manifestations, causes, and pathophysiology. At the forefront of understanding lie pivotal factors such as Helicobacter pylori infection, nonsteroidal anti-inflammatory drugs usage, lifestyle choices, and stress, each wielding significant influence over ulcer development and progression. The intricate interplay of these factors underscores the complexity of enteric ulcer etiology. Helicobacter pylori infection—a prevalent culprit—inflicts …
Published in Research and Reviews: A Journal of Medicine · Vol. 14, Issue 1, 2024 · pp. 25–40 Read article
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HPV and Cardiovascular Risk: Unpacking a Novel Link Between Viral Infection and Heart Disease
Abstract: Human papillomavirus (HPV) is best known for its oncogenic potential, yet a growing body of evidence suggests that persistent HPV infection may also contribute to cardiovascular disease (CVD). In 2025, pooled analyses and conference reports galvanized attention by estimating that HPV‐positive individuals have ~40% higher risk of CVD and approximately double the risk of coronary artery disease (CAD) compared with HPV‐negative peers, even after adjustment for traditional risk factors. These …
Published in International Journal of Virus Studies · Vol. 2, Issue 2, 2025 · pp. 1–5 Read article
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Elderly Healthcare Using Federated Learning Approach
Abstract: The healthcare system for elderly people faces several challenges, which can be addressed using advanced machine learning models. These models can help monitor chronic diseases, detect falls, and provide personalized health recommendations. The study uses comprehensive datasets like MIMIC-III/IV, WESAD, and UCIHAR to explore human movements, device limitations, and the differences in fall occurrences. A detailed review of existing literature discusses current technologies for activity monitoring and fall detection, focusing …
Published in Current Trends in Information Technology · Vol. 16, Issue 1, 2025 · pp. 13–23 Read article
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In Silico Investigation of 2,3-Dihydrobenzofuran from Centella asiatica: A Possible Pioneer in the Management of Tetanus
Abstract: Objective: Tetanus toxin (TeNT) is a neuroprotein toxin, the most toxic known. They have three functional domains and are structurally similar. They possess an N-terminal catalytic section (light chain), an internal domain for heavy-chain translocation (HN domain), and a C-terminal receptor binding domain for the heavy chain (Hc domain or RBD). Tetanus, an acute nerve-affecting disease, is provoked by a toxin-producing bacterium called Clostridium tetani. This bacterium is environmental, Gram-positive, …
Published in Research and Reviews : Journal of Computational Biology · Vol. 13, Issue 1, 2024 · pp. 19–30 Read article
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A Study on Clinical Characteristics and The Impact Of Covid-19 In Hemodialysis Patients
Abstract: Background: The Corona Viruses Disease-19 pandemic has severely impacted Hemodialysis patients, who are vulnerable due to compromised immune systems and underlying comorbidities. Frequent Dialysis center visits increase their exposure risk to severe acute respiratory syndrome- Coronavirus Disease, and chronic inflammation, uremia, and immunosenescence may impair their immune response. Methods: This retrospective study included 60 Hemodialysis patients diagnosed with COVID-19 between January -July 2024. Data on demographics, clinical characteristics, laboratory results …
Published in International Journal of Biomedical Innovations and Engineering · Vol. 3, Issue 2, 2025 Read article
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Plant Bioactive Metabolites and Their Role in the Prevention and Control of Dental Diseases and Infections.
Abstract: The oral diseases, including dental caries and periodontitis, affect masses worldwide, and have historically been managed with synthetic antimicrobials that cause deleterious side effects, leading to mounting bacterial resistance. Consequently, contemporary dentistry is rapidly shifting toward phytomedicine using plant bioactive molecules, such as polyphenols, terpenes, anthraquinones (berberin, eugenol, curcumin, catechins, allicin, and azadirachtin. These compounds offer potent antimicrobial, anti-inflammatory, and tissue-regenerative properties that are crucial for preventing and curing dental …
Published in Emerging Trends in Metabolites · Vol. 3, Issue 1, 2026 · pp. 47–66 Read article
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Non-Invasive Glucose Monitoring Device Using Max30102 Sensor
Abstract: Diabetes mellitus is a chronic metabolic disorder affecting millions globally, requiring continuous blood glucose monitoring to prevent complications such as cardiovascular disease, kidney failure, neuropathy, and retinopathy. Conventional invasive finger- prick techniques result in pain, skin irritation, and an increased risk of infection, which lowers patient compliance, particularly in young patients and the elderly. This paper presents a non-invasive glucose monitoring prototype using the MAX30102 optical biosensor interfaced with the …
Published in Journal of Instrumentation Technology & Innovations · Vol. 16, Issue 1, 2026 · pp. 36–44 Read article
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Exploring Glucagon-like peptide-1 as a Target Protein for Diabetes Mellitus Treatment: Molecular Docking and Pharmacokinetic Analysis of Phytocompounds from Momordica charantia
Abstract: Objective: This study aimed to use molecular docking techniques to explore the potential of GLP-1 (glucagon-like peptide-1) as a target protein for the treatment of diabetes mellitus, a chronic metabolic disease marked by elevated blood glucose levels. Given its crucial role in maintaining insulin secretion and glucose homeostasis, GLP-1 may serve as a future target for diabetes therapy. Method: The study employed a multi-phase method. Initially, protein extraction was carried …
Published in International Journal of Biochemistry and Biomolecule Research · Vol. 2, Issue 1, 2024 · pp. 8–20 Read article
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Immunological and Genetic Markers of Rheumatoid Arthritis Among Women in North India: A Case-Control Study
Abstract: Background: Rheumatoid arthritis (RA) is an autoimmune disease systemically afflicting women marked by chronic inflammation around the involved joints leading to joints destruction. It has both endocrinological and immunological associations as well as genetic associations but data pertaining to women of North India is scanty. Objective: This case-control study was done to evaluate the presence and significance of major immunological and genetic markers of RA in North Indian women with …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 3, Issue 2, 2025 · pp. 1–10 Read article
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Personalized Nutrition and Exercise: Pioneering the Path to Precision Medicine
Abstract: Preventive healthcare is about to undergo a major shift thanks to the personalised exercise and nutrition paradigm, which is based on precision medicine concepts. In order to create tailored recommendations for improving health outcomes and preventing chronic diseases, this article explores the integration of genetic profiling, metabolic evaluation, and lifestyle factors. A person's response to food and exercise depends heavily on genetic and metabolic variances, which emphasises the need of …
Published in Emerging Trends in Personalized Medicines · Vol. 1, Issue 2, 2024 · pp. 42–46 Read article
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A Systematic Review on Peptic Ulcer Disease and its Pharmacological Treatment
Abstract: A chronic gastrointestinal condition known as Peptic Ulcer Disease (PUD) is typified by the formation of ulcers or mucosal erosions in the proximal duodenum and stomach. In the pathophysiology of PUD, the equilibrium between defensive processes like mucus and bicarbonate secretion, mucosal blood flow, and prostaglandin production, and aggressive factors such stomach acid secretion, pepsin activity, and Helicobacter pylori infection, is upset. Although stress and food have historically been blamed, …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 16, Issue 1, 2026 · pp. 76–84 Read article