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465 articles for “Toxic effects”
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Research Insight: Toxicology
Abstract: Toxicology is an apprehensive study of the antagonistic effects of chemicals on living entities. It also studies the detrimental special effects of chemical, biological and physical proxies in biological systems that inaugurate the extent of loss in living organisms. The association between dose and its effects on the wide-open entity is of prodigious implication in toxicology. The factors that sway chemical toxicity include dosage, the route of exposure, the species, …
Published in Research and Reviews: A Journal of Toxicology · Vol. 5, Issue 2, 2015 · pp. 23–26 Read article
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Drug-Induced Liver Injury: Hepatotoxicity and Treatment - A Literature Review
Abstract: Drug-induced liver injury (DILI) is a major clinical and regulatory challenge, posing risks to patient safety and drug development worldwide. As the primary organ responsible for xenobiotic metabolism, the liver is particularly susceptible to toxic injury from prescription drugs, over-the-counter medications, herbal products, and dietary supplements. Drug-induced liver injury (DILI) accounts for a substantial proportion of acute liver failure cases and remains a leading cause of post-marketing drug withdrawal. Its …
Published in Research and Reviews: A Journal of Toxicology · Vol. 16, Issue 1, 2026 · pp. 1–17 Read article
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Agricultural Waste Management System by using Waste Product
Abstract: - Agricultural wastes are non-product outputs of production and process of agricultural goods which will contain material that may profit man however whose economic values are less than the cost of collection, transportation, and processing for beneficial use. Estimates of agricultural waste arising are rare, however they're typically thought of as contributory a big proportion of the whole waste material within the developed world. Agricultural development is typically in the …
Published in Research and Reviews : Journal of Crop science and Technology · Vol. 8, Issue 2, 2019 · pp. 1–8 Read article
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Biochemical Assays of Crude and Purified Oxycarotenoid Extracts Isolated from Coriander Leaves and their Effect on Oxidative Stability of Oils by Rancimat Assay
Abstract: Antioxidants are important substances in the fight against the damage done by free radicals that are produced by oxidative stress. Antioxidants are available in various forms as dietary supplements/synthetic forms. Because of their toxicity and side effects, the extensive use of many of these synthetic antioxidants is ruled out. Most nutritionist agrees that, the natural food is the best source of antioxidants. Dietary antioxidants have the ability to scavenge free …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 8, Issue 1, 2018 · pp. 1–10 Read article
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Role of Models in Predicting Toxicity Criteria against Arsenic Toxicity Test Exposed to Therapon Jarbua (Forsskal, 1775)
Abstract: Prediction of safe concentration, no-effect concentration for reduced animal usage in chronic toxicity test was attempted as well as to create a toxicity criteria limit for arsenic using Therapon jarbua in static renewal acute toxicity test. The LC50 value derived was 3.95 (3.43–4.58) mg/L arsenic. The derived LC50 was applied for prediction of safe concentration leading to a value of 39.5 µg/L. The raw survival and mortality data was fed …
Published in Journal of Energy, Environment & Carbon Credits · Vol. 3, Issue 3, 2013 · pp. 22–28 Read article
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Phytochemical Screening, Proximate Analysis and Acute Toxicity Study of Ethanolic Extract of Launaea taraxacifolia on Visceral Organs of Albino Rats
Abstract: Despite increase in the acceptance of herbs for the treatment of certain diseases, there are limited information on the effectiveness, safety and toxicity of herbs. In this study, proximate analysis, phytochemical screening and acute toxicity studies on the herbal recipe, Launaea taraxacifolia were carried out. Constituents of Launaea taraxacifolia were extracted using ethanol. Phytochemical screening and proximate analysis were carried out on the extract. Fifteen (15) albino rats, divided into …
Published in Research and Reviews: A Journal of Toxicology · Vol. 4, Issue 3, 2014 · pp. 1–8 Read article
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Comparison of the Effects of Voriconazole and its Nanogel form on Aspergillus Flavus Isolates in Vitro
Abstract: Aspergillus species are one of the most critical environmental fungi and are considered as a severe factor in causing hospital infections of foreign origin. Objective: Aspergillus flavus is a saprophytic and pathogenic fungus and is found all over the world. In clinical isolates, the voriconazole drug effectively affects more than 95% of Aspergillus isolates. These common drugs have limitations for maximum effect in patients, so nanomedicines are designed and manufactured …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 12, Issue 3, 2024 · pp. 14–20 Read article
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Tadbeer-e-advia: A Unani Process of Detoxification of Poisonous Drugs: A Review
Abstract: The Unani System of Medicines (USM) is one of the oldest traditional systems of medicine, and deals with drugs of plants, animals and minerals origin where maximum are of plant origin. Most of the drugs used in USM are believed to be safe. But among the drugs of these origins are known for their toxic, undesirable and harmful effects. Unani Scholars divided all the drugs into four categories first, second, …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 9, Issue 2, 2020 · pp. 1–5 Read article
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Studies on acute toxicity and behavioral responses of Heteropneustes fossilis (Linn.) exposed to Diazinon
Abstract: In the present study, acute toxicity of the organophosphate pesticide, diazinon, was evaluated under experimental condition to adult Heteropneustes fossilis. The 96 h LC50 with 95% confidence limits of Heteropneustes fossilis is 16.56 (14.32- 18.04) mg/l. None of the unexposed control fish died during the experiment. Mortality rate between each dose and mortality rate between 24-96 h depending on time was correlated. In the fish, significant relationship (p<0.05) was recorded …
Published in Research and Reviews: A Journal of Toxicology · Vol. 8, Issue 1, 2018 · pp. 9–13 Read article
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Nanotechnology in Surgical Drains: Reducing Infections and Promoting Healing Post-Surgery
Abstract: Surgical drains are widely used in postoperative care to evacuate accumulated fluids, minimize dead space, and reduce complications such as hematoma and seroma formation. Despite their clinical importance, conventional drains are frequently associated with retrograde bacterial migration, biofilm formation, and increased risk of surgical site infections (SSIs), which contribute significantly to postoperative morbidity and prolonged hospital stay. Recent advancements in nanotechnology have enabled the development of nano-functionalized surgical drains with …
Published in Research and Reviews : Journal of Surgery · Vol. 15, Issue 2, 2026 · pp. 54–67 Read article
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Review on Darunaj-aqrabi (Doronicum hookeri C.B. Clarke): an Unexplored Medicinal Plant of Unani System of Medicine
Abstract: Introduction: The rhizomes of medicinal plant Darunaj-aqrabi (Doronicum hookeri C.B. Clarke ex Hook.f.) (Family Asteraceae) has long been used in Unani system of medicine (USM) as Cardiac tonic (invigorative and exhilarant), nervine tonic, carminative, protective of the foetus, antidotary etc. in different dosage forms. It is included in specific drugs for heart and is much valuable for palpitation. Because of having antidotal characteristics and protective (corrective) attributes, the rhizomes are …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 9, Issue 2, 2020 · pp. 41–52 Read article
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Unlocking Potential: Capecitabine’s Evolution as an Anticancer Wonder Drug
Abstract: Capecitabine, a precursor to 5-fluorouracil (5-FU), is Anticancer Drug in treating solid tumors like colorectal, breast, and gastric cancers. Its mechanism involves converting to 5-FU mainly within tumor cells, reducing toxicity while maximizing effectiveness. Besides being effective alone, it is also valuable in combination therapies, showcasing its versatility in cancer treatment. This review explores the transformative journey of capecitabine as a pivotal anticancer drug. Beginning with an introduction to its …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 11, Issue 2, 2024 · pp. 17–24 Read article
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Develop And Assess a Multifunctional Herbal Face Pack
Abstract: This study aims to develop and assess a multifunctional herbal face pack that reduces tan lines and brightens skin through the trituration of herbal ingredients. Following preparation, the formulation is assessed using a variety of criteria, including, extrudability, stability, irritant test, physicochemical, and organoleptic factors. Physically, the formulation was found to be good, devoid of skin irritation, and able to retain its consistency even after stability in storage. An herbal …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 11, Issue 2, 2024 · pp. 1–7 Read article
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A Review on Banana Fiber Reinforced Polymer Composites through Advanced Surface Treatments and Manufacturing Techniques
Abstract: In today's rapidly evolving world, heightened environmental concerns and stringent government regulations have spurred scientists and researchers to seek biodegradable and renewable alternatives to synthetic materials. Natural fibers, derived from resources like banana, jute, bagasse, and sisal, offer distinct advantages such as low density, comparable strength, non-toxicity, cost-effectiveness, and minimal waste disposal issues over synthetic counterparts. Extensive research has explored the potential applications of these natural fibers, with banana fibers …
Published in Trends in Mechanical Engineering & Technology · Vol. 14, Issue 3, 2024 Read article
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Review on Unveiling the Shadow of Hyperpigmentation
Abstract: Natural products offer promising solutions for treating skin pigmentation disorders due to their non-toxic properties and effective mechanisms of action. Studies highlight their safety and efficacy through methods such as cytotoxicity tests, tyrosinase activity assays, and melanogenesis inhibition evaluations. Advanced delivery systems like liposomes and nanoparticles further enhance their performance by improving solubility and skin penetration. Skin pigmentation disorders, influenced by factors such as UV radiation, hormonal changes, and inflammation, …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 15, Issue 2, 2025 · pp. 59–66 Read article
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Reinventing Drug Delivery Through Cutting-Edge Nanotechnology
Abstract: Nanotechnology has emerged as a revolutionary platform in the field of drug delivery, offering novel strategies for the precise, efficient, and controlled delivery of therapeutic agents. The integration of nanocarriers, such as liposomes, polymeric nanoparticles, dendrimers, micelles, and inorganic nanoparticles, has significantly enhanced drug solubility, stability, bioavailability, and targeted delivery to specific tissues or cells. Targeted drug delivery systems based on nanotechnology minimize off-target effects, reduce systemic toxicity, and improve …
Published in Trends in Drug Delivery · Vol. 12, Issue 3, 2025 · pp. 44–61 Read article
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Bacteriocin Production and Characterization Obtained from Lactobacillus sakei
Abstract: Natural preservatives such as bacteriocins become an attractive alternative in the substitution of chemical preservatives, which have eventual potential for toxicity and carcinogenic effect. In this study, a bacteriocin was produced from a strain of Lactobacillus sakei, isolated from Italian salami. The data obtained in this paper revealed that the antimicrobial activity of bacteriocin was higher than 85% in the assays using the Gram-positive (Staphylococcus aureus) and Gram-negative (Escherichia coli) …
Published in Research & Reviews : Journal of Food Science & Technology · Vol. 10, Issue 1, 2021 · pp. 27–36 Read article
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Ayurvedic Herbs in the Management of Geriatric Problems: A Review
Abstract: AbstractGeriatric problems are of much concern for medical professionals in the present day scenario. More toxic and adverse effect of allopathic medicines is reported in common problems of old age due to altered metabolic activities in old age. Ayurvedic herbs are better in the management of geriatric problems. These herbs are classified in classical Ayurvedic texts as Rasayana. The Rasayana is a specialized type of treatment that leads to an …
Published in Research & Reviews : Journal of Herbal Science · Vol. 3, Issue 2, 2014 · pp. 17–24 Read article
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The Bhut Jolokia Chilly and the Capsaicin Factor
Abstract: AbstractThe Bhut Jolokia was accepted by Guinness World Records in 2007 as the world’s spiciest chilly. It has a hotness of 1,041,427 SHU (Scoville Heat Units). The chilly is grown and eaten in India’s northeastern states such as Arunachal Pradesh, Assam, Nagaland, Manipur, Meghalaya, Sikkim and Tripura, referred as the hot spots for chilly diversity due to their unique ecological conditions and also, in countries like Bangladesh and Sri Lanka. …
Published in Research & Reviews : Journal of Herbal Science · Vol. 8, Issue 3, 2019 · pp. 9–12 Read article
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Research and Industrial Insight: Toxicology
Abstract: Toxicology is a division of biology, chemistry, and medicine related with the study of the special effects of chemicals on breathing organisms. It also studies the injurious effects of chemical, biological and physical mediators in biological system that founds the degree of destruction in living organisms. The correlation between dose and its belongings on the exposed organism is of great importance in toxicology. A factor that inspires the chemical toxicity …
Published in Research and Reviews: A Journal of Toxicology · Vol. 5, Issue 1, 2015 · pp. 36–40 Read article