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559 articles for “Structured” (ranking capped at the first 2,000 matches — narrow the search to see the rest)
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An Extensive Analysis of Computer-Aided Drug Design for Novel Psychotropic and Neurological Substances
Abstract: A comprehensive review of the use of computer-aided drug design (CADD) in the creation of innovative neurologic and neuropsychiatric medications is given in this article. It discusses the challenges in traditional drug discovery approaches and highlights the role of computational methods in accelerating the identification and optimization of drug candidates targeting psychiatric and neurological disorders. The method of finding new drugs has been completely transformed by Computer-Aided Drug Design (CADD), …
Published in International Journal of Brain Sciences · Vol. 1, Issue 2, 2024 · pp. 19–27 Read article
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A Review on Anesthetic Drug Discovery with Computer Aided Drug Design
Abstract: In contemporary medicine, anaesthesia is essential for enabling surgical procedures, pain control, and patient comfort. Finding and creating safe and efficient anaesthetics is crucial to enhancing patient outcomes and developing the medical field. In this review, we provide a comprehensive overview of anesthetic drug discovery with a focus on the integration of computer-aided drug design (CADD) methodologies. Beginning with an exploration of anesthesia mechanisms and targets, we delve into the …
Published in International Journal of Antibiotics Read article
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Fluorescence Emission Enhancement in Crystalline Photonic Structures
Abstract: One of the two ways that a material that has absorbed light or other electromagnetic radiation can emit light is through fluorescence. Fluorspar is a substance that can be added to welding compounds to facilitate easier flow; the word fluorescent is derived from the Latin fluere, which means "to flow." LED lights, clothing that glows in "black light," or light sources that contain UV or blue light, and butterflies like …
Published in International Journal of Crystalline Materials · Vol. 1, Issue 2, 2024 · pp. 35–48 Read article
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Composition and Structure of Oil Finishing Agent †
Abstract: Use of oil finishing agent is widely used in the process of production of carbon fibers to impart unusual and exceptional strength to the carbon fibers, the key load-bearing component, of the advanced materials, namely, carbon fiber reinforced composites (CFRPs). CFRPs are being widely used in the realm of aeronautics, astronautics, aeronautics, geonautics, sports equipment, and many more. However, quite often, much of the knowledge on the composition of oil …
Published in International Journal of Crystalline Materials · Vol. 2, Issue 1, 2025 · pp. 01–10 Read article
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Effectiveness of A structured teaching program on Leucorrhoea and it's management for women of Reproductive age group at selected college in Honavar
Abstract: Leucorrhea, also known as leucorrhea, is a white, yellow, or green discharge from a woman's vagina, which may be normal or asign of an infection. Leucorrhea is common during pregnancy and is typically normal if the discharge is thin, white, and odorless.Physiological leucorrhea is a condition that occurs in young women several months to a year after the onset of menstruation. It sometimes occurs in newborn girls and usually lasts …
Published in International Journal of Women's Health Nursing And Practices · Vol. 2, Issue 2, 2024 · pp. 40–44 Read article
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Molecular Pharmacokinetics and Structural Docking of Phenolic Acids for Targeting NF-κB Pathway Components in Inflammation and Fibrosis: A Computational Approach Toward Therapeutic Discovery
Abstract: Inflammation and Fibrosis are critical pathological processes associated with various chronic diseases, often mediated by the nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) signaling pathway. This study investigates the therapeutic potential of phenolic acids as modulators of the NF-κB pathway, aiming to identify novel ligands that can effectively interact with key components of this signaling cascade. A comprehensive computational approach was employed, utilizing molecular docking, pharmacological screening, and post-docking …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 3, Issue 1, 2025 · pp. 14–31 Read article
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A Study to Assess the Effectiveness of Self-Instructional Module on Knowledge of Electrocardiogram Among Staff Nurse in a Selected Hospital in Mahagaon
Abstract: Objectives: This study aimed to evaluate the staff nurses' knowledge of electrocardiograms (ECG) and to determine the impact of a structured teaching program in improving their understanding of the subject. Methodology: An evaluative research design was employed for this study. The study involved 22 staff nurses chosen through simple random sampling and was carried out at Sant Gajanan Maharaj Rural Hospital, Mahagaon. A structured knowledge questionnaire was used to gather …
Published in International Journal of Evidence Based Nursing And Practices · Vol. 3, Issue 1, 2025 · pp. 7–27 Read article
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Exploring Antimalarial Activity of Chalcone Derivatives through QSAR
Abstract: Background: The core structure of chalcones contains a reactive α,β-unsaturated system within the aromatic rings, which plays a key role in mediating various biological effects. These effects include enzyme inhibition, anticancer activity, anti-inflammatory properties, as well as antibacterial, antifungal, antimalarial, antiprotozoal, and anti-filarial actions.Modifying the structure by introducing substituent groups to the aromatic ring can enhance potency, reduce toxicity, and expand their range of pharmacological actions. Methods: A total of …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 3, Issue 2, 2025 · pp. 1–6 Read article
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Pharmacokinetic Profiling and Molecular Docking of Carvacrol and Structural Analogs: Targeting Quorum Sensing Proteins to Disrupt Biofilm-Mediated Antimicrobial Resistance in Multidrug-Resistant Bacterial Pathogen
Abstract: Antibiotic resistance, particularly in Pseudomonas aeruginosa, has become a major global health threat, exacerbated by the organism's ability to form biofilms and regulate virulence through quorum sensing (QS). The LuxR and LasR receptors are key regulators in this process, influencing both pathogenicity and antibiotic resistance. This study investigates potential QS inhibitors targeting these receptors as a strategy to mitigate antibiotic resistance. The primary objective was to identify novel ligands that …
Published in International Journal of Biochemistry and Biomolecule Research · Vol. 3, Issue 2, 2025 · pp. 43–61 Read article
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Crystallinity of commercial carbon fibers from X-ray diffraction (XRD) studies
Abstract: Sized carbon fibers have commercial significance. Such carbon fibers serves has excellent reinforcing material with the polymer resin filler matrix leading to the formation of carbon fiber reinforced composites (CFRCs). Polarized carbon fibers find applications in the realms of health, energy, environment, defence, catalysis and smart materials. For brevities sake, the focus of the current research paper is only on the structural characterization of carbon fibers using XRD. The structure …
Published in International Journal of Photochemistry and Photochemical Research · Vol. 1, Issue 1, 2023 · pp. 17–27 Read article
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Study the Impact of Corrosive Pollutants on Building Materials Corrosion
Abstract: Reinforced concrete structures (RCS) may be made more resistant to corrosion by using fiber reinforced polymers (FRP). One of the primary concerns with reinforced concrete constructions is corrosion. It causes disintegration in building material components by interactions with salts, acids, and alkalis. Both within and outside of reinforced properties, pollutants and effluents accelerate disbanding. When bio-waste and building materials come into contact, microorganisms and macro organisms, grow and emit acid …
Published in International Journal of Fracture Mechanics and Damage Science · Vol. 2, Issue 2, 2024 · pp. 20–29 Read article
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Time Series Forecasting Based on PyAF and fbProphet
Abstract: Time series forecasting is the technique of predicting future events using previous data. Time series data includes information that is collected and recorded at regular intervals, such as daily stock prices, monthly sales figures, or hourly temperature readings. The purpose of time series forecasting is to use previous data to create accurate forecasts about the future values of a given variable. This can be beneficial for a range of applications, …
Published in International Journal of Information Security Engineering · Vol. 1, Issue 1, 2023 · pp. 32–36 Read article
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Examining Research Patterns and Concepts in Relation to Frameworks for Sustainable Supply Chain Management (SSCM)
Abstract: Structures abound in writing about Sustainable Supply Chain Management (SSCM). Nevertheless, no effort has been made to date to identify the anomalies in the systems that are in place now and the associated research trends. This research is motivated primarily by a survey of SSCM structures and feature abnormalities. The analysis also promotes new applications and aids in the analysis of SSCM structure constructions and exploration patterns. Using the Scopus …
Published in International Journal of Industrial and Product Design Engineering · Vol. 1, Issue 2, 2023 · pp. 26–41 Read article
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Exploring Glucagon-like peptide-1 as a Target Protein for Diabetes Mellitus Treatment: Molecular Docking and Pharmacokinetic Analysis of Phytocompounds from Momordica charantia
Abstract: Objective: This study aimed to use molecular docking techniques to explore the potential of GLP-1 (glucagon-like peptide-1) as a target protein for the treatment of diabetes mellitus, a chronic metabolic disease marked by elevated blood glucose levels. Given its crucial role in maintaining insulin secretion and glucose homeostasis, GLP-1 may serve as a future target for diabetes therapy. Method: The study employed a multi-phase method. Initially, protein extraction was carried …
Published in International Journal of Biochemistry and Biomolecule Research · Vol. 2, Issue 1, 2024 · pp. 8–20 Read article
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Gene Annotation of Cancer Vaccine for Homo sapiens
Abstract: Objectives: Gene annotation helps us to deduce the structural and functional aspects of a gene that encodes for a functional protein in our body. Thus, by determining the coding sequence and gene location we can derive meaningful insights as to what these genes do in our body. In this study, an unknown gene, cancer vaccine for Homo sapiens has been studied and annotated. Methods: This study was based on a …
Published in International Journal of Molecular Biotechnological Research · Vol. 2, Issue 1, 2024 · pp. 1–14 Read article
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Youthful Students’ Perception of The Nursing Profession: A Preliminary Single-group Research
Abstract: Aim: This study had four objectives: (1) examine how adolescents perceive nursing before and after organized teaching programs; (2) examine how adolescents perceive nursing after structured teaching programs; (3) compare pre-test and post-test results to assess the efficacy of a structured teaching program; (4) relate the mean improvement in nursing image to particular demographic factors. Background: This study assists in identifying potential areas for improvement or any potential interventions to …
Published in International Journal of Community Health Nursing And Practices · Vol. 1, Issue 2, 2023 Read article
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Influence of Die Design Parameters and Mechanical Properties of AA5083 Through Equal Channel Angular Pressing Technique
Abstract: Refinement of the grain structure in bulk Materials is achieved using the Equal Channel Angular Pressing process. The material is pass through a die in this procedure that has two channels that meet at a particular angle. Finer grains are formed as a result of the material's deformation when it passes through die. The creation of ultra-fine grains is influenced by a number of die design characteristics. The effects of …
Published in International Journal of Manufacturing and Production Engineering · Vol. 2, Issue 2, 2024 · pp. 33–47 Read article
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Advancements in Drug Design Technology and Its Impact on COVID-19 Treatment
Abstract: The deadly coronavirus disease 19 (COVID-19) pandemic has recently spread, raising concerns about global health. The search for novel therapeutic compounds is made more necessary by the persistent problem of the absence of licensed medications or vaccinations. By saving money and time, computer-aided drug design has sped up the process of finding and developing new drugs. The structured-based and ligand-based drug discovery subcategories of computer-aided drug design (CADD) are the …
Published in International Journal of Virus Studies · Vol. 1, Issue 1, 2024 · pp. 1–15 Read article
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A Study on Determination of Seismic Susceptibility in Existing Buildings in Ward No-18 of Dhaka North Using Rapid Visual Screening (RVS) Method
Abstract: The research work presents a comprehensive analysis of the Rapid Visual Screening (RVS) method applied to 200 buildings in Ward No. 18 of Dhaka North City. The study focused on assessing the seismic vulnerability of these structures, categorizing them into damage grades based on the RVS evaluation. Strikingly, the findings revealed that 191 out of the 200 buildings were classified as damage grade 5, signifying severe structural deficiencies. In contrast, …
Published in International Journal of Climate Conditions · Vol. 1, Issue 1, 2024 · pp. 28–37 Read article
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A Descriptive Study to Assess the Effectiveness of Instructional Modules on Knowledge Regarding Challenges Faced by Rural Community People on Cancer Preventive Measures Among People Living in the Selected Community Area, Palakkad District
Abstract: This study employed a quantitative approach with a descriptive study design to assess the knowledge and challenges faced by rural communities regarding cancer preventive measures. A total of sixty participants were selected using purposive sampling, which is non-probability based. Data were gathered through a semi-structured questionnaire to capture demographic information, alongside a structured questionnaire specifically designed to evaluate knowledge on cancer prevention challenges within the rural population. The collected data …
Published in International Journal of Oncological Nursing and Practices · Vol. 2, Issue 2, 2024 · pp. 26–33 Read article