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276 articles for “Express.js”
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The Evolution and Impact of Numbers: From Ancient Tallies to Quantum Computing: Review Article on Numbers
Abstract: Numbers are among the most fundamental constructs in human civilization, serving as the backbone of mathematics, science, technology, and virtually every aspect of daily life. They represent not only quantities and measures but also relationships, structures, and patterns that underpin the fabric of human understanding. From the earliest tallies etched on bones by prehistoric humans to the sophisticated numerical systems embedded in today’s artificial intelligence and quantum computing, the evolution …
Published in Research & Reviews: Discrete Mathematical Structures · Vol. 12, Issue 3, 2025 · pp. 15–19 Read article
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Epigenetic Modifications in Health, Disease, and Precision Therapeutics (From Genome to Epigenome)
Abstract: Introduction: Epigenetic alterations play a crucial role in regulating gene expression in both normal physiological and disease states. These reversible modifications—such as DNA methylation, histone acetylation, phosphorylation, ubiquitination, and chromatin remodelling—are increasingly implicated in complex diseases including cancer and neurodegenerative disorders. Despite advances in standard therapeutic approaches, patient responses remain variable, largely due to genetic heterogeneity and epigenetic dysregulation. This highlights the need for incorporating epigenetic understanding into personalized medicine. …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 15, Issue 1, 2026 Read article
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REVIEW OF PHARMACOEPIGENETICS: BRIDGING EPIGENETICS AND PERSONALIZED MEDICINE
Abstract: Pharmacoepigenetics is an emerging field that explores how alterations in gene expression, independent of DNA sequence changes, influence individual responses to drugs. Unlike pharmacogenetics, which focuses primarily on genetic variation, pharmacoepigenetics integrates genetic, environmental, and lifestyle factors to explain interindividual differences in drug efficacy, toxicity, and resistance. Key epigenetic mechanisms including DNA methylation, histone modifications, non-coding RNAs, and RNA methylation play critical roles in regulating drug metabolism and therapeutic outcomes. …
Published in International Journal of Molecular Biotechnological Research · Vol. 4, Issue 1, 2026 Read article
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Systolic-Predominant Hypertension and the Aging Heart: A Cross-Sectional Study on LVH and Cardiovascular Riskss
Abstract: Background: Systolic-predominant hypertension, defined as a systolic blood pressure ≥140 mm Hg with diastolic pressure <90 mm Hg, is the most prevalent form of hypertension in the elderly. It arises primarily due to age-related arterial stiffening and baroreceptor dysfunction. Once considered a benign outcome of aging, systolic-predominant hypertension is now recognized as a major risk factor for cardiovascular morbidity and mortality. Aim and Objective: To evaluate the cardiac status and …
Published in Research and Reviews: A Journal of Medicine · Vol. 16, Issue 1, 2026 · pp. 13–24 Read article
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Depression Detection Using AI with Chatbot Support
Abstract: Depression is a major global health concern and a significant contributor to suicide rates worldwide. India reports a high number of suicide cases, making the early detection of mental distress and depression essential for timely intervention. This research presents an AI-based system for depression detection that integrates deep learning, natural language processing (NLP), and a chatbot for user support. The system analyzes facial expressions using convolutional neural networks (CNNs) and …
Published in Research & Reviews: A Journal of Embedded System & Applications · Vol. 14, Issue 1, 2025 · pp. 01–08 Read article
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The Role of English Language in Communication: Multidisciplinary Perspectives
Abstract: The English language performs an essential role in communication, serving as the universal medium through which people exchange data, express feelings, and build relationships. This research explores the importance of language in communication, examining its role in human interactions, the dynamics of effective communication, and the socio-cultural impact of language. Communication is a skill that involves a systematic and continuous process of speaking, listening, and understanding. We are also taught …
Published in Emerging Trends in Languages · Vol. 3, Issue 1, 2026 · pp. 1–7 Read article
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Machine Learning Based Sentiment Analysis of Student Feedback in Higher Education
Abstract: Educational institutions routinely collect feedback from students to understand their perceptions of academic programs, infrastructure, and campus facilities, to improve the overall quality of the college environment. In current practice, feedback is often gathered using numerical or grade-based rating systems, which tend to oversimplify student opinions and may overlook important details related to their level of satisfaction. In contrast, open-ended textual feedback allows students to clearly express their views, concerns, …
Published in International Journal of Data Structure Studies · Vol. 4, Issue 1, 2026 · pp. 01–10 Read article
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Effects of Reels and short videos on human mind and Academic Life
Abstract: The rapid rise of short-form video platforms such as Instagram Reels, TikTok, and YouTube Shorts has fundamentally reshaped the way people consume information and entertainment. While these applications offer quick engagement and social connection, their excessive use has raised serious concerns about their psychological and academic impacts. This research investigates the relationship between short-form video addiction, mindfulness, academic anxiety, and academic engagement among university students. Drawing upon the theoretical framework …
Published in International Journal of Behavioral Sciences · Vol. 3, Issue 2, 2026 Read article
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Television Media and Children: A Sociological Insight on Rural Society in Punjab
Abstract: The present paper deals with to understand the media forms of television and digital media as an influential agent of socialisation in contemporary society, especially among the children. The increasing accessibility of television and digital media, especially in the rural society of Punjab, have greatly impacted the patterns of childhood socialisation, cultural norms, religious practices, attitudes, and routine behaviour. During the study it is found that television continues to occupy …
Published in International Journal of Children · Vol. 3, Issue 2, 2026 · pp. 21–34 Read article
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Explainable Sentiment Mining Model in Mental Health Forums for Emotion Classification and Justification
Abstract: Understanding and interpreting emotions expressed in online mental health discussions plays a crucial role in enabling early detection of psychological distress and facilitating timely interventions. As individuals increasingly turn to digital platforms to share personal experiences and seek support, automated systems capable of accurately identifying emotional states can significantly assist clinicians, moderators, and support communities. This paper presents a deep learning–based sentiment mining and emotion classification framework specifically designed to …
Published in International Journal of Algorithms Design and Analysis Review · Vol. 4, Issue 1, 2026 · pp. 22–32 Read article
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Perspectives on ‘Kamsaharitaki’: an Ayurvedic Formulation for COVID-19 related Multisystem Inflammatory Syndrome (MIS)
Abstract: Background and Aim: Angiotensin-converting enzyme 2 receptor (ACE2), together with Transmembrane protease serine 2 (TMPRSS2), is a protein receptor for SARS-CoV-2 virus in the host subject; expression of ACE2 and TMPRSS2 reveals the multidimensional character of COVID-19 infection. SARS-CoV-2 Prominently induces pulmonary and systemic injury with other synergistic mechanisms. Preexisting chronic inflammatory conditions markedly sustain and aggravate the severity and cytokine storm. Inflammatory responses are closely linked with COVID-19 severity …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy Read article
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Eco-friendly Azadirachta Indica Ash and Miscanthus Fiber Brick for Carbon Neutrality Environment
Abstract: Naturally grown fiber are not utilized properly they are neglected as wastes. These resources are thrown away due to insufficient research being conducted to discover viable uses for naturally existing fibres. These byproducts have a wide variety of applications in the manufacturing sector, notably in the construction sector. The prospective applications of miscanthus fibre, which may be found growing wild in uncultivated places, are investigated in this research. The production …
Published in Journal of Polymer & Composites Read article
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Synthesis of Brassinosteroid with Signaling and Response to Abiotic Stress: Review
Abstract: Brassinosteroids (BRs) are a group of plant steroid hormones with multiple roles in plant growth, development, and responses to stresses and signaling functions to promote cell expansion and cell division and plays a role in etiolation and reproduction. The entire synthetic pathway of sterol biosynthesis is brassinolide (BL) from the general campesterol synthesis pathway in Arabidopsis. Campesterol converts to BL in two different ways campesterol dependent or campesterol independent pathway. …
Published in Research & Reviews : Journal of Botany Read article
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Network Pharmacology and Molecular Docking Approach to Reveal the Underlying Mechanisms of Isorhamnetin in the Treatment of Lymphangitis Carcinomatosis
Abstract: Objective: Lymphangitic carcinomatosis (LC) is a tumor that spreads through lung lymphatics and is most commonly seen secondary to adenocarcinoma. In the majority of cases, LC is a result of tumor cells spreading through the lymphatic system. However, approximately 20% of LC cases can be attributed to lymphangitis caused by tumors obstructing lymphatic drainage. This blockage commonly occurs near the lung hilum, where a centrally located mass can cause inflammation …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 1, Issue 1, 2023 · pp. 28–45 Read article
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Impact of Project Complexities on Cost Overruns
Abstract: As decision-making and goal setting become more challenging due to complexity, there is growing consensus that comprehending complexity is essential for project management. However, there have been concerns expressed regarding how complexity can be quantified in a reliable way that takes into account structural, dynamic, and interaction factors. Current operational definitions of complex projects based on size and budget, have been called into doubt. What can be done is to …
Published in International Journal of Architectural Design and Planning Read article
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Pharmacoinformatic Based Screening Of Phytocompound Epigallocatechin Gallate To Identify As A Potential Bcl-2 Inhibitor
Abstract: Objectives: The B-cell lymphoma-2 (Bcl-2) is a protein that is particularly though to be involved in preventing apoptosis. Bcl-2 family members also essential for cancer survival, and its over expression has been linked to tumor genesis, development and resistance to anticancer treatments. The Bcl-2 family of members that inhibit apoptosis is a promising target for the creation of anticancer drugs. Methods: The study was based on computational approach using different …
Published in International Journal of Bioinformatics and Computational Biology Read article
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Cultural Heritage of Punjab: A Shift in Outlook and Output—A Case Study of the Historical Town of Sirhind
Abstract: Cultural heritage is an expression of ways of living developed by a community and passed on from generation to generation. This could be the tangible assets, such as buildings, monuments, archaeological sites, artifacts, landscape, and intangible assets such as oral traditions, folklore, language, and knowledge. Though all these can be viewed, analyzed, studied separately, they cannot be experienced as standalone entities. The understanding of our cultural heritage is fragmented and …
Published in International Journal of Architectural Design and Planning Read article
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NLP Revolution in Education Feedback Analysis: Trends and Challenges
Abstract: Artificial Intelligence (AI) is a rapidly growing area of study in many domains like research and business. Various subsets of AI, such as Machine Learning, Deep Learning, and Natural Language Processing (NLP), are employed to address diverse aspects of data processing and modeling. This review is about the impact of AI on the education system and students feedback for the analysis is required for the enhancement of the technology used …
Published in International Journal of Wireless Security and Networks · Vol. 1, Issue 1, 2023 · pp. 21–25 Read article
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Identification of Secondary Metabolites from Zingiber officinale as Inhibitors for Keap 1-Nrf2 small Molecules through Molecular Docking Techniques
Abstract: Objective: Therapeutic plants aid in treating cancer-based cell signaling pathways and preventing certain risk factors. Zingiber officinale has a variety of anti-inflammatory characteristics also contributing to enhanced immunity, reducing cancer risk and used to target the KEAP NRF2. When overexpressed in response to oxidative stress and DNA damage, elevates the risk of developing multiple cancers. NRF2 cellular sensors, which also control and coordinate their expression aid in defending healthy cells …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 1, Issue 2, 2023 · pp. 35–48 Read article
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Study of Finite State Machines as Language Recognizer
Abstract: Finite State Machines (FSMs) play a fundamental role in computer science and linguistics as language recognizers. This study presents an exploration of the principles and applications of FSMs as efficient tools for recognizing formal languages. The study delves into the theoretical foundations of FSMs and their practical implementation in various language recognition tasks. The fundamental ideas of FSMs, including as states, transitions, and input symbols, are introduced in this study. …
Published in International Journal of Data Structure Studies · Vol. 1, Issue 1, 2023 · pp. 18–24 Read article