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282 articles for “Clinical Outcome”
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A Study to Assess the Risk Factors Associated with Sudden Death in Population on Hemodialysis
Abstract: Background: Patients with chronic kidney disease (CKD) receiving maintenance hemodialysis (HD) experience disproportionately high mortality, with sudden death remaining a leading cause. Multiple clinical, biochemical, and care-related factors influence outcomes, yet comprehensive risk stratification models and the role of dialysis timing and early nephrology care remain inadequately explored in resource-limited settings. Objectives: This study aimed to (i) identify clinical and biochemical risk factors associated with mortality in HD patients, (ii) …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 16, Issue 1, 2026 · pp. 14–19 Read article
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Horizons in Neuralgia Care: Addressing Unmet Needs and Future Prospects
Abstract: Neuralgia refers to intense, sharp, and often chronic pain resulting from damage or irritation to nerves. It is typically characterized by sudden, shooting pain along the course of a nerve, significantly impairing daily functioning and impacting both physical and emotional well-being. Given its intensity and chronic nature, neuralgia presents a complex challenge in clinical management, emphasizing the importance of timely diagnosis and effective intervention to improve patient outcomes. This comprehensive …
Published in International Journal of Brain Sciences · Vol. 2, Issue 2, 2025 · pp. 1–8 Read article
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Artificial Intelligence for Improved Healthcare: A Case Study and Applications
Abstract: Artificial intelligence (AI) in healthcare ushers in a revolutionary period of innovation, but it also brings with it significant ethical dilemmas. This paper explores the complex relationship between AI and healthcare, emphasizing both its useful applications and the moral conundrums that arise. Ethical issues span a wide range, including patient privacy, transparency, accountability, and the unintentional reinforcement of biases in AI algorithms. Privacy concerns take center stage as healthcare providers …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 12, Issue 1, 2025 · pp. 1–12 Read article
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Early Detection of Heart Disease using Machine Learning Techniques
Abstract: Coronary illness stays one of the main sources of death around the world. Exact expectations of coronary illness can altogether work on quiet results by empowering early intercession and customized treatment plans. Throughout the course of many recent years, AI (ML) methods have been extensively investigated for anticipating coronary illness, attribuFig to their remarkable capacity to analyze complex data patterns and generate precise predictions based on historical clinical records. With …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 12, Issue 3, 2025 · pp. 34–45 Read article
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Treatment of Acute RVMI Complicated by High-Grade Bradycardia-Induced Shock Using Pacing-PTCA-ICT Combination
Abstract: Acute RVMI (right ventricular myocardial infarction), which would be possibly followed by bradycardia-induced shock, may perpetuate a vicious circle very quickly and result in short-term adverse outcomes as cardiac arrest and long-term outcomes as angina pectoris or recurrent myocardial infarction. In order to block this circle, emergent combination of temporary pacing and PTCA (percutaneous transluminal coronary angioplasty) may be necessary, and especially, in unexpected case that the occlused lesion is …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 13, Issue 1, 2024 · pp. 19–23 Read article
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REVIEW OF PHARMACOEPIGENETICS: BRIDGING EPIGENETICS AND PERSONALIZED MEDICINE
Abstract: Pharmacoepigenetics is an emerging field that explores how alterations in gene expression, independent of DNA sequence changes, influence individual responses to drugs. Unlike pharmacogenetics, which focuses primarily on genetic variation, pharmacoepigenetics integrates genetic, environmental, and lifestyle factors to explain interindividual differences in drug efficacy, toxicity, and resistance. Key epigenetic mechanisms including DNA methylation, histone modifications, non-coding RNAs, and RNA methylation play critical roles in regulating drug metabolism and therapeutic outcomes. …
Published in International Journal of Molecular Biotechnological Research · Vol. 4, Issue 1, 2026 Read article
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Precision Medicine Approaches for Cancer Therapy Recent and Advance
Abstract: Recent advances in biotechnology have made it possible to identify intricate and distinctive biological characteristics linked to carcinogenesis. Proteomic and RNA studies, immunological markers, tumor and cell-free DNA profiling, and other methods are utilized to find these traits in order to optimize anticancer treatment for specific patients. In recent years, the focus of clinical trials has shifted considerably to enhance treatment outcomes in cancer therapy. Rather than being primarily centered …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 14, Issue 1, 2025 · pp. 1–11 Read article
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Role of W.A.R. Score in Predicting Wound Infection
Abstract: In clinical practice, chronic wounds are a major difficulty that are frequently made worse by the infection risk. However, the lack of precise standards for evaluating the risk of infection and establishing the need for and length of time for systemic antibiotics leads to the overuse and abuse of these drugs, which increases the risk of side effects and the development of antibiotic resistance. To close this gap, the development …
Published in Emerging Trends in Personalized Medicines · Vol. 1, Issue 1, 2024 · pp. 33–38 Read article
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A Compressive Review of Traditional Medicine System of Naturopathy (Nature): Evaluation, Standardization of Alternative Medicine
Abstract: Naturopathy is a therapeutic approach that combines scientific principles with the natural laws of the body. It focuses on using natural methods to promote healing and overall well-being. This traditional practice combines various techniques, such as herbal medicine, nutritional guidance, hydrotherapy, and physical therapy, to treat the underlying causes of illnesses rather than just managing symptoms. The growing interest in alternative medicine necessitates a comprehensive evaluation and standardization of naturopathic …
Published in Research and Reviews : A Journal of Ayurvedic Science, Yoga and Naturopathy · Vol. 12, Issue 1, 2025 · pp. 22–29 Read article
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Optimizing Anesthesia for Major Surgery: The Role of Sequential Combined Spinal-Epidural Technique
Abstract: The Combined Spinal Epidural (CSE) approach has been widely employed over the last decade because it achieves rapid onset and substantial blockage while also allowing for the modification or prolongation of the block. Background: Sequential spinal-epidural anesthesia (SSEA) combines the rapid onset and dense blockade of spinal anesthesia with the prolonged duration and adjustable analgesia of epidural anesthesia. This technique is particularly beneficial in major surgeries requiring prolonged operative time …
Published in Research and Reviews : Journal of Surgery · Vol. 14, Issue 2, 2025 · pp. 12–18 Read article
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Effect of Lifestyle Counseling for Women with Gestational Diabetes on Fetal and Maternal Outcomes at Assiut University
Abstract: Gestational diabetes mellitus is a serious and often ignored risk to the health of mothers and children. Aim of the Study: To assess the effect of lifestyle counseling among women with gestational diabetes on fetal and maternal outcomes at Assiut University. Materials and Method: Antenatal care clinics hosted a pre-test and post-test for a quasi-experimental study. Sample: A total of 365 women in total attended antenatal care clinics. Setting of …
Published in International Journal of Women's Health Nursing And Practices · Vol. 1, Issue 2, 2023 · pp. 21–35 Read article
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CNN-Based Diagnosis of Skin Cancer from Dermoscopic Images
Abstract: Skin cancer has become one of the diseases widely spread over the globe, with melanoma becoming a severe threat to one’s health. Detection of such diseases at the initial stage saves an individual from drastic damage. Using a Convolutional Neural Network (CNN) for detecting skin cancer through image classification as benign or malignant provides significant support to dermatological practice and reduces dependence solely on subjective visual examination. Dermatologists often face …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 15, Issue 1, 2026 · pp. 37–42 Read article
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Monoclonal antibodies in targeted cancer therapy advances, resistance mechanisms, and next-gen formats (Bispesifics, ADCs)
Abstract: Breast cancer is one of the leading causes of cancer-related morbidity and death worldwide, which emphasizes the need for more effective and focused treatment strategies. antibody-mediated drug delivery techniques. Specifically, antibody–drug conjugates (ADCs) have emerged as a potential approach that combines the specificity of monoclonal antibodies with the potent cytotoxicity of anticancer drugs. By selectively targeting tumor-associated antigens, ADCs enhance drug accumulation within cancer cells while minimizing systemic toxicity associated …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 17, Issue 2, 2026 Read article
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Neurodegeneration and Cognitive Decline: Causes, Consequences, and Treatment Approaches
Abstract: Neurodegenerative diseases gradually destroy nerve cells, often leading to fatal outcomes. The phrase includes a wide range of clinical problems, such as a variety of Neurological conditions include movement disorders, like Parkinson’s disease (PD) and progressive cognitive impairments, with Alzheimer’s disease (AD) being the most common among them. A loss of neurones and synaptic connections, typically in later life, is a prevalent feature of Usually, the onset and development of …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 3, Issue 1, 2025 · pp. 47–59 Read article
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A prospective investigation into seroma monitoring and skin flap anchoring following Mastectomy
Abstract: Breast cancer remains a significant global health challenge, often necessitating life-saving mastectomy surgeries. However, post-mastectomy complications—such as seroma formation and skin flap necrosis—can still impact a patient’s recovery and overall quality of life. This prospective study examines the effectiveness of seroma monitoring and skin flap anchoring following mastectomy in reducing these problems. Few prospective studies addressing these particular concerns were found in a thorough literature assessment. To fill this void, …
Published in Research and Reviews : Journal of Surgery · Vol. 14, Issue 2, 2025 Read article
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Investigating the Impact of Viral Infections on Pharmacokinetics and Pharmacodynamics of Antiviral Drugs
Abstract: The emergence and re-emergence of viral infections pose significant challenges to public health, necessitating a comprehensive understanding of how these infections impact the pharmacokinetics and pharmacodynamics of antiviral drugs. This review explores the intricate interactions between viral pathophysiology and the pharmacological effects of antiviral agents. Factors such as viral replication dynamics, host immune responses, and the genetic variability of both viruses and hosts significantly influence drug absorption, distribution, metabolism, and …
Published in International Journal of Virus Studies · Vol. 1, Issue 2, 2024 · pp. 23–30 Read article
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Enhancing the User Experience of Asthma Inhalers: A Redesign Approach
Abstract: Asthma is a widespread chronic respiratory condition impacting millions globally, presenting significant challenges in its management and treatment. While conventional inhalers effectively administer medication, they often encounter usability issues, hindering patient adherence and treatment outcomes. This abstract delineates the development and potential impact of a redesigned asthma inhaler aimed at addressing these challenges. Incorporating human-centered design principles, the revamped inhaler prioritizes usability, portability, and effectiveness to enhance the overall management …
Published in International Journal of Solid State Innovations & Research · Vol. 1, Issue 2, 2023 · pp. 32–36 Read article
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Effect of Local Application of Phenytoin on Wound Healing in Surgical Wounds: A Scientific Review
Abstract: Surgical wound healing is a dynamic biological process influenced by local tissue response, vascularity, infection control, and systemic patient factors. Delayed wound healing contributes significantly to postoperative morbidity and healthcare costs. Phenytoin, a hydantoin derivative traditionally used as an antiepileptic agent, has demonstrated unexpected wound-healing properties when applied topically. This review critically evaluates experimental and clinical evidence regarding the role of locally applied phenytoin in enhancing wound healing in surgical …
Published in Research and Reviews : Journal of Surgery · Vol. 15, Issue 1, 2026 · pp. 15–19 Read article
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A Study on the Comparative Changes in Nutritional Status in Follow-Up of End Stage Renal Disease Patients
Abstract: Dialysis Disequilibrium Syndrome (DDS) is a rare but serious neurological complication associated with hemodialysis, particularly during the initiation phase or in patients with high metabolic derangements. It is characterized by a range of neurological symptoms resulting from rapid shifts in plasma osmolality, leading to cerebral edema. Despite advancements in dialysis techniques, DDS continues to pose a clinical challenge due to its unpredictable nature and potential for severe outcomes. The present …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 16, Issue 1, 2026 · pp. 9–13 Read article
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Uterine Leiomyosarcoma: A Diagnostic Dilemma
Abstract: Tumours that fall under the category of uterine malignancies include carcinosarcomas, leiomyosarcomas, endometrial stromal sarcomas, and undifferentiated sarcomas. Of them, leiomyosarcoma is the most common subtype, while still quite uncommon—it accounts for 1% to 2% of uterine cancers. Since postmenopausal bleeding is typically present in leiomyosarcomas, prompt detection is essential for successful treatment. This case study features a 50-year-old female patient who had postmenopausal bleeding, which is a common sign …
Published in International Journal of Pathogens · Vol. 1, Issue 1, 2024 · pp. 38–42 Read article