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88 articles for “Clinical Implication”
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Dual-Stream Deep Learning Framework for Brain CT Image Classification and Implications for Polymer Composite Neuro Implant Evaluation
Abstract: Early and accurate classification of brain CT images is critical for diagnosing conditions such as aneurysms, tumors, and related lesions. We present a dual-stream image-classification framework that fuses convolutional neural network (CNN) features with handcrafted Histogram of Oriented Gradients (HOG) descriptors to jointly capture global semantics and local textural cues. The pipeline begins with modality unification via pixel-wise averaging to form a fused input, which is then processed in parallel …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 172–179 Read article
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Relation of p53 Codon 72 Polymorphism with Breast Cancer Risk in DPR Korea Women
Abstract: Background: The p53 codon 72 polymorphism (rs1042522) is a single-nucleotide polymorphism (SNP) in exon 4 of p53 gene, resulting in the expression of either arginine (Arg), which encodes CGC, or proline (Pro), which encodes CCC. The p53 codon 72 polymorphism have been implicated as a risk factor for various cancers including breast cancer. We have investigated the association of the Arg/Pro polymorphism at codon 72 of p53 gene with breast …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 7, Issue 1, 2020 · pp. 23–30 Read article
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Environmental implications of hospital laundry services
Abstract: The environmental implications of hospital laundry services differ markedly from those in the hospitality sector. This distinction stems from the need to handle hospital linens soiled with various bodily fluids, necessitating disinfection before washing. Hospital linens encompass a diverse range of fabrics used throughout medical facilities, including mattresses, pillowcases, blankets, bed sheets, towels, curtains, screens, and aprons. Maintaining the cleanliness of hospital linens is crucial for patient comfort, reducing discomfort, …
Published in Research and Reviews: A Journal of Toxicology · Vol. 13, Issue 2, 2023 · pp. 39–43 Read article
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Epigenetic Modifications in Health, Disease, and Precision Therapeutics (From Genome to Epigenome)
Abstract: Introduction: Epigenetic alterations play a crucial role in regulating gene expression in both normal physiological and disease states. These reversible modifications—such as DNA methylation, histone acetylation, phosphorylation, ubiquitination, and chromatin remodelling—are increasingly implicated in complex diseases including cancer and neurodegenerative disorders. Despite advances in standard therapeutic approaches, patient responses remain variable, largely due to genetic heterogeneity and epigenetic dysregulation. This highlights the need for incorporating epigenetic understanding into personalized medicine. …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 15, Issue 1, 2026 Read article
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Epidermolysis Bullosa and Its Role in Cervical Cancer: An Overview
Abstract: Epidermolysis Bullosa is a group of uncommon genetic disorders that primarily affect the skin and mucous membranes. It is marked by severe skin fragility and the formation of blisters even after minor trauma. Traditionally, the focus of Epidermolysis Bullosa research has been on its dermatological manifestations, which include recurrent blistering, scarring, and the potential for infections due to the compromised skin barrier. However, recent advancements in Epidermolysis Bullosa research have …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 2, Issue 2, 2024 · pp. 14–18 Read article
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Hiv/aids pandemic and national security
Abstract: The Acquired Immune Deficiency Syndrome (AIDS) is disease caused by the Human Immunodeficiency Virus (HIV), whose clinical manifestation results in the failure of the Immune system to function normally to protect the individual from being attacked or threatened by diseases. The world's attention was drawn to the first observed case in 1981 and a second in 1982 in two different socio-cultural and economic settings and the world then fails to …
Published in Research and Reviews : A Journal of Immunology · Vol. 15, Issue 2, 2025 · pp. 53–66 Read article
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Crispr Cas – Revolutionizing Modern Therapies and Beyond
Abstract: CRISPR-Cas technology has emerged as a transformative tool in modern molecular biology, revolutionizing both fundamental research and clinical applications. This RNA-guided gene-editing system enables precise and efficient genomic modifications, offering unprecedented potential for addressing genetic disorders, infectious diseases, and oncological conditions through innovative therapeutic interventions. The inherent specificity and programmability of CRISPR-Cas systems have facilitated breakthroughs in diverse fields, including precision medicine, regenerative therapies, and immuno-oncology. Beyond its therapeutic applications, …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 3, Issue 1, 2025 · pp. 25–38 Read article
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Exploring Challenges in Clinical Learning and the Impact of Structured Teaching on Infection Control Knowledge and Attitudes Among Nursing Students
Abstract: Living a healthy lifestyle is essential for preventing chronic diseases and maintaining physical, psychological, and social well-being. The present study, titled “Exploring Challenges in Clinical Learning and the Impact of Structured Teaching on Infection Control Knowledge and Attitudes among Nursing Students” aimed to address key challenges faced by nursing students and evaluate the impact of a structured teaching program. The study employed a quantitative research approach using a pre-experimental design …
Published in Research and Reviews : A Journal of Immunology · Vol. 15, Issue 1, 2025 · pp. 42–47 Read article