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1969 articles for “quantum mechanics/molecular mechanics (QM/MM)” (ranking capped at the first 2,000 matches — narrow the search to see the rest)
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Assessment of Decellularization Techniques for Fabrication of Tubular Submucosal Scaffolds from Small Intestine for Application in Oesophageal Tissue Engineering
Abstract: In this ground-breaking study, we sought to create superior tubular scaffolds for tissue engineering by utilizing small intestine submucosa (SIS), a remarkable biomaterial with outstanding therapeutic potential. We investigated two standard detergent-perfusion procedures, peracetic acid under perfusion and classic peracetic acid-agitation, to decellularize tubular SIS, with the goal of generating scaffolds with consistent and reliable properties for oesophageal tissue engineering. To assess biocompatibility, we employed metabolic research, microscopy, mechanical tests, …
Published in Journal of Polymer & Composites · Vol. 11, Issue 3, 2023 · pp. 30–38 Read article
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Application of Grey Wolf Optimizer (GWO) strategy for Malware Analysis
Abstract: The ever-evolving landscape of cybersecurity necessitates continuous advancements in malware analysis techniques. This study explores the deployment of the Grey Wolf Optimizer (GWO) algorithm as a novel bio-inspired optimization mechanism to address the challenges posed by modern malware threats. The primary objective is to enhance various facets of malware analysis, including feature selection, parameter optimization, and the overall efficacy of malware detection models. The study begins by introducing the GWO …
Published in International Journal of Wireless Security and Networks · Vol. 1, Issue 2, 2023 · pp. 43–53 Read article
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Minimum Energy Criteria for Machining to Determine Energy-Productivity Relationship
Abstract: In this research segment, cutting rates were changed while depth of cut and feed rate remained fixed. The results of cutting using a standard uncoated carbide insert were compared. Cutting speeds were maintained at a constant. After determining the optimal cutting condition for the equipment and material. To determine optimal tool life and cutting speed, turning operations were performed. In industrial cutting operations, flank wear reduces tool life. For single-point, …
Published in Journal of Polymer & Composites · Vol. 11, Issue 4, 2023 · pp. 81–94 Read article
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Inhibition of PI3K/Akt/mTOR Signaling Pathway by Vitis Vinifera Phytocompounds: A Promising Strategy for Supressing Colorectal Cancer Growth and Metastasis
Abstract: Objectives: Colorectal cancer was not typically identified a few decades ago. Today, with almost 900 000 fatalities each year, it is the fourth most dangerous cancer in the world. Colorectal cancer is responsible for about 10% of all cancer diagnoses annually and cancer-related deaths worldwide. It is the second most common type of cancer in women and the third most common type in men. Incidence and death are roughly 25% …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 1, Issue 2, 2023 · pp. 64–75 Read article
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Revolutionizing Geopolymer Composites: Unveiling Intelligent Wall Facades and Precision PZT Sensors for Vibration Analysis
Abstract: Evaluating the mechanical performance and environmental benefits of geopolymer composites is imperative for sustainable alternatives in construction. This study presents an innovative circular PZT-based sensor that effectively captures transient vibrations within concrete structures, demonstrating its validity in comparison to standard surface-mounted accelerometers. The research also elucidates the influence of sensor orientation on capturing various vibrational modes of concrete. Furthermore, the embedded PZT sensors provide valuable insights into the evolving mechanical …
Published in Journal of Polymer & Composites · Vol. 11, Issue 13, 2023 · pp. 59–73 Read article
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REPEATED MOPs VS DUAL APPROACH IN ACCELERATED ORTHODONTICS
Abstract: In contemporary orthodontics, there is a pressing need to minimize treatment duration, which is often a concern for both orthodontic specialists and patients. Prolonged treatment periods not only pose logistical challenges but also increase the risks of various dental issues such as cavities, periodontal problems, chronic discomfort, and root resorption. Accelerated orthodontics has emerged as a promising solution to address these challenges. Numerous efforts have been undertaken to expedite orthodontic …
Published in Research and Reviews: A Journal of Dentistry · Vol. 15, Issue 1, 2024 · pp. 16–21 Read article
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Zolmitriptan Mouth Dissolving Tablets: Development of Formulas and Invitro Evaluation
Abstract: Pharma Burst ODT super disintegrants were used in different concentrations to manufacture Zolmitriptan fast dissolving tablets by a direct compression method. With a 28° angle of repose, there is good flow. The densities for bulk and tapped materials are 0.410 (g/ml) and 0.500 (g/ml), respectively. The compressibility index and Hausner ratio have values of 19.05 and 1.24, correspondingly. According to IP standard, weight variation test results range from 121.4 mg …
Published in Emerging Trends in Personalized Medicines · Vol. 1, Issue 2, 2024 · pp. 1–15 Read article
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Enhancing the Performance of Evacuated Tube Heat Pipe Solar Collector Using CuO Nanofluid
Abstract: Renewable energy is an important component of sustainable development technologies that meet current demands without risking future generations' ability to meet their own. Due to fast expanding energy consumption and environmental concerns, many international scholars are seeking an alternate approach to fulfill future energy demand. Due to its abundance and pure nature, solar energy appears to be the most enticing option in this case. Because of their ease of use, …
Published in Journal of Polymer & Composites · Vol. 11, Issue 8, 2023 · pp. 393–407 Read article
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Application of pET28a Vector for the Over Expression of Recombinant Human Tim23 Protein in E. coli and its Validation by Immunoblotting
Abstract: This study aimed to produce recombinant human Tim23 protein by molecular cloning, expression, and purification. Amplification of human TIM23 was carried out by polymerase chain reaction (PCR) and cloned into DH5α cells. The pET28a-human TIM23 was transformed into BL21DE3 and expressed the gene by IPTG induction. Recombinant pure human Tim23 antigen was prepared, and injected into rabbits and polyclonal antibodies were raised, which was confirmed by western blotting. The transformed …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 14, Issue 1, 2024 · pp. 32–44 Read article
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Performance Evaluation of Eco-friendly Cutting Fluid in Machining Process—An Approach towards Environmentally Friendly Production
Abstract: The machining industry's evolving environmental consciousness has prompted a growing demand for cutting fluids devoid of chlorine and sulphur, thus fostering sustainable machining practices. This surge in demand is driven by mounting apprehensions over environmental contamination and worker safety. As the industry transitions to modern cutting fluids, it becomes imperative to comprehend their effectiveness and the optimal machine parameters required for their deployment in the turning process. In our current …
Published in Journal of Polymer & Composites · Vol. 11, Issue 12, 2023 · pp. 149–160 Read article
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Study and Thermal Analysis of a Rectangular Duct with Z-shaped Baffle Using Ansys
Abstract: This project aims to enhance heat transfer in a rectangular duct by utilizing Z-shaped baffles. It involves creating a 3D CAD model using SolidWorks and validating it in ANSYS Fluent 2019 R2. The study focuses on analyzing the effect of baffle arrangement, height, and angle on heat transfer rate. Comparative analysis is conducted between rectangular ducts with a 60° angle and heights of 4 mm, 6 mm, and 8 mm. …
Published in International Journal of Energy and Thermal Applications · Vol. 1, Issue 2, 2023 · pp. 14–30 Read article
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Determining the Characteristics of Concrete Composed of Different types of Aggregates
Abstract: This study investigates the influence of recycled aggregates on the compressive strength of concrete designed for medium workability. Various replacement proportions of recycled aggregates (0%, 50%, 60%, and 100%) were examined using conventional mix design methods, specifically focusing on 10 mm recycled aggregates' impact. The specimens comprised 100% recycled aggregate, with a combination of 60% 20 mm and 40% 10 mm sizes. Compressive strength analyses were conducted at 7 and …
Published in Journal of Structural Engineering and Management · Vol. 11, Issue 1, 2024 · pp. 1–5 Read article
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Isolation, Purification and Characterization of Antimicrobial peptide produced by Saccharomyces boulardii №6569
Abstract: Object: To identify microorganisms that are newly isolated biologically and microbiologically and determine their characteristics by purifying AMP produced by yeast. Methods: We measured the antibacterial activity of AMP using microliquid dilution and turbidity methods and purified them using membrane filtration and gel filtration methods. The molecular weight of AMP produced by Saccharomyces boulardii was measured using Acquity UPLC SQD-2 and MS. Results: We confirmed that yeast-№18, identified biologically and …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 14, Issue 1, 2024 · pp. 7–18 Read article
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Dynamic Performance Enhancement of Polymer Composites through Metaheuristic machinining optimization
Abstract: This work aims to provide an optimization of meta-heuristic algorithms in order to improve the dynamic behavior of composite materials utilized in various practical engineering tasks. Based on the Comprehensive literature review it has been observed that composite sandwich panels with PVC foam cores accomplished mechanical characteristics superior than those ones that were produced on PU foam core mainly in flexural, compression, and impact tests Thus the study establishes the …
Published in Journal of Polymer & Composites · Vol. 12, Issue 2, 2024 · pp. 114–129 Read article
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Can Screw-only fixations of ACPHT acetabular fractures enhance stability as the standard buttress plate fixation provides?
Abstract: Background: Of acetabular fractures, anterior column posterior hemi-transverse(ACPHT) fractures commonly occur after a fall onto the hip in elderly population. When displaced in these fractures, open reduction and internal fixation using plate and screws is usually required to achieve good functional outcomes. The open procedures, however, involve high complication rates due to surgical invasion; therefore, percutaneous techniques by screw-only constructs have been advocated to minimize these complications. The purpose of …
Published in Research and Reviews : Journal of Surgery · Vol. 13, Issue 1, 2024 · pp. 64–73 Read article
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Exploring Composite Materials for Energy Harvesting in Electric Vehicles: A Comprehensive Review
Abstract: Energy harvesting, an increasingly dynamic field, holds promise for powering various devices by extracting energy from surrounding sources. Composite materials, blending mechanical and electrical properties, emerge as ideal candidates for energy harvesting applications. Despite their burgeoning utilization in electric vehicle (EV) energy capture, the full realization of their potential remains subject to ongoing evaluation. This editorial comprehensively examines composite materials' mechanical properties, electrical conduction, thermal stability, and affordability concerning EV …
Published in Journal of Polymer & Composites · Vol. 12, Issue 3, 2024 · pp. 1–15 Read article
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A Perspective Review on Role of Environmental Pollutants in Developing Neurodegenerative Diseases
Abstract: As human society progresses towards industrialization, an excess number of environmental pollutants are released to our ecosystem, which significantly contribute in causing various health issues primarily associated with neurodegenerative diseases such as cognitive disorder, dementia, anxiety, Alzheimer, Parkinson etc. Because of their high global occurrence, these diseases have attracted attention in recent decades, however, the etiology of these diseases remains unclear. Pollutants are discharged into the environment by natural events …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 14, Issue 2, 2024 · pp. 1–18 Read article
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Recombinant Human EGF in Wound Healing: 3D Computational Insights
Abstract: A Growth Factor represents a naturally-occurring compound with the remarkable ability to incite cellular growth, proliferation, and differentiation. Typically manifesting as either a protein or a steroid hormone, these factors wield significant influence over an array of cellular activities. Their pivotal role lies in the regulation of diverse cellular processes, often serving as catalysts for cell specialization and maturation, a characteristic that distinguishes them from one another. For instance, bone …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 11, Issue 2, 2024 · pp. 6–10 Read article
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Effect of Functionalization on glass transition temperature of Carbon Fiber reinforced Epoxy Nanocomposites using MD Simulation
Abstract: As we all know that the mechanical characterization of any material plays a vital role in performance of the material throughout its life cycle. One of the major parameters in calculating the mechanical properties of carbon fiber reinforced nanocomposite is glass temperature. Understanding glass transition behaviour of polymer nanocomposites are crucial for optimizing their mechanical properties and performance. We used “Molecular dynamics simulations” to calculate sequel functionalization effect on glass …
Published in Journal of Polymer & Composites · Vol. 12, Issue 5, 2024 · pp. 1–8 Read article
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E-World: Battery Management system in E-cycle
Abstract: As e-cycles gain popularity for their eco- friendly transportation and convenience, understanding the dynamics of these key systems is crucial. The report explores various braking mechanisms, such as mechanical and hydraulic disc brakes, and explains their operational principles and safety implications. Additionally, it examines the technologies used for acceleration in e-cycles, focusing on motor types, control systems, and throttle mechanisms. By utilizing the battery management system, we have the capability …
Published in Journal of Alternate Energy Sources & Technologies · Vol. 15, Issue 2, 2024 · pp. 6–11 Read article