Search
1908 articles for “beclin-1” (ranking capped at the first 2,000 matches — narrow the search to see the rest)
Nothing matched all of your words, so these match any of them.
-
Extrapolations of Periwinkle Secondary Metabolites as Multitarget Inhibitor of Breast Cancer Proteins
Abstract: Objective: Breast cancer is considered one of the most common and dangerous forms of cancer. It is a significant public health issue on a global scale. The study estimates that 10.0 million people will die from cancer this year, and 19.3 million people will develop the disease overall (BC). In this computation approach, nowadays emphasizes new drug discovery, the target protein epidermal growth factor receptor (EGFR) (5UGB), estrogen receptor (ER) …
Published in International Journal of Biochemistry and Biomolecule Research · Vol. 1, Issue 1, 2023 · pp. 36–49 Read article
-
Prototype Model Development and Design Analysis of A Solar Tricycle for Physically Challenged People in India
Abstract: Society is greatly concerned about the mobility of individuals with physical disabilities. The scarcity of energy resources and the issue of pollution are currently the primary concerns. These issues can be resolved by employing alternative energy sources such as solar power. This paper presents an overview of the existing solar tricycles designed for those with disabilities. It also improves a handicapped-friendly solar-powered tricycle. The goal is to reduce handicapped people's …
Published in International Journal of Mechanical Dynamics and Systems Analysis · Vol. 1, Issue 1, 2023 · pp. 43–56 Read article
-
In vivo Modulatory Effect of Clerodendrum Splendens (Glory Blossom) in Aluminum Induced Alzheimer Diseases and Lonchocarpus Sericeus in Rotenone Induced Parkinson’s Disease on Na+/K+ Atpase (Sodium Pump) in the Cerebral Tissues of Male Albino Wister Rats
Abstract: Elegant research has shown that plants are useful for both curative and preventive purpose on the humans populous. Prevalent among diseases associated with humans are neurological diseases which affect a large sector of the population especially the elderly. The most common neurological diseases are Parkinson and Alzheimer disease which affect a large sector of the brain and also cause an imbalance in brain electrolyte. Among such electrolytic mechanisms of the …
Published in International Journal of Biochemistry and Biomolecule Research · Vol. 1, Issue 2, 2023 · pp. 31–36 Read article
-
Assessing the Child–Parent Relationship Between Working and Non-working Mothers in a Selected Community of Bhubaneswar
Abstract: Introduction: Two categories of mothers exist: those who work outside the home, referred to as working mothers, and those who stay at home, often described as housewives. Working mothers may allocate quality time to their children, even if the amount of time is not necessarily large. On the other hand, non-working mothers not only manage household responsibilities but also provide care for their children and the entire family. Methods: A …
Published in International Journal of Evidence Based Nursing And Practices · Vol. 1, Issue 2, 2023 · pp. 27–33 Read article
-
Oral Self-examination: An Approach for Early Recognition of Oral Cancer Among Factory Workers: An Experimental Study
Abstract: Background: Cancer is a worldwide concern and ranks among the most dreaded illnesses across the globe. Oral cancers are one common cancer among all cancers. Objectives: To measure the existing knowledge concerning oral self-examination for timely recognition of oral cancer among factory workers and to develop and administer a planned health education programme of oral self-examination for early recognition of oral cancer among factory workers. 40 factory workers were selected …
Published in International Journal of Oncological Nursing and Practices · Vol. 1, Issue 2, 2023 · pp. 22–26 Read article
-
Pharmacophore mapping, 3D QSAR, docking, and ADME prediction studies of novel Benzothiazinone derivatives
Abstract: Background Tuberculosis is a major public health concern worldwide which is caused by Mycobacterium tuberculosis. DprE1 (Decaprenyl Phosphoryl Ribose 2’- Epimerase) is the most challenging target for development of novel anti- tubercular agents because it is a small protein and located into cytoplasmic membrane. So, novel anti-TB drugs did not bound effectively with it. DprE1 catalyzes the oxidation of the 2’ hydroxyl group of DPR (Decaprenyl Phosphoryl D- Ribose) …
Published in International Journal of Antibiotics · Vol. 1, Issue 1, 2024 · pp. 59–82 Read article
-
The Influence of Fresh Raffia Palm Trunk on the Bioremediation of Oil-Based Drill
Abstract: This study determines the effect of fresh raffia palm for biodegradation of oil-based drill cuttings bioremediation. The experiment was conducted at the rivers institute of Agricultural research and training (RIART) located at the Rivers State University, Port Harcourt. Samples of oil-based drill cuttings were bulked in eleven reactors with four replications (T1, T2, T3-T11). The physiochemical properties of the initial drill cuttings were analyzed. Also, the physiochemical properties of the …
Published in International Journal of Pollution: Prevention & Control · Vol. 1, Issue 2, 2023 · pp. 41–48 Read article
-
An effort for maximizing the material removal rate during the wire cutting of difficult to machine Inconel X750 using electric discharge machining process
Abstract: The growing demand for harder materials with exceptional hardness poses a significant challenge for industries as achieving precise machining becomes increasingly tricky. The Inconel family of materials, renowned for their hardness, has been extensively studied. However, with the continuous introduction of new materials, the scope of research remains vast. In this context, Inconel X750, a corrosion and oxidation resistance, nickel-chromium-based alloy with excellent hardness, has gained attention. Despite its significance, …
Published in Journal of Polymer & Composites · Vol. 11, Issue 12, 2023 · pp. 1–17 Read article
-
Experimental investigation of thermally grown Indium film’s structural and tribological properties
Abstract: Indium thin film growth found numerous applications, such as cold welding of infrared detectors and readout-integrated circuits (ROIC) to form sensor chips. In film is grown on the Si substrate by thermal evaporation. The XRD results indicated the tetragonal bcc phase in the (101) preferential plane. Scanning electron microscopy (SEM) indicated an uniform, continuous film covering the whole surface. The EDS examination confirmed the pure In film. The atomic force …
Published in Journal of Polymer & Composites · Vol. 11, Issue 12, 2023 · pp. 58–66 Read article
-
Multi-Response Optimization of Turning Parameters with Vikor-Entropy Method on Machining of AA6061-TiB2 In-Situ Composites
Abstract: In the manufacturing and metal cutting industries, the quality of the surface and strength is essential in defining the surface finish; an excellent surface finish indicates excellent quality in the product. The influence of machining parameters speed, feed and depth of cut on responses like material removal rate, surface roughness and Power consumption on turning of AA6061-TiB2 composites is investigated using the VIKOR-ENTROPY method. The effects of changing parameters on …
Published in Journal of Polymer & Composites · Vol. 11, Issue 8, 2023 · pp. 256–268 Read article
-
Enhancing Strength and Durability: A Study of Mortar Blocks with Steel Slag Incorporation and the Development of Steel Slag Lime and Cement Blocks
Abstract: This study is focused on investigating the strength and durability properties of mortar cubes made with slag cement and incorporating Ultra Fine Steel Slag (SS) as a potential replacement for natural fine aggregates (FNA). In some instances, the cement was entirely replaced with hydrated lime to develop the blocks. A battery of tests, including assessments of compressive strength, acid resistance, sulfate resistance, water absorption, and void analysis, were carried out …
Published in Journal of Polymer & Composites · Vol. 11, Issue 8, 2023 · pp. 233–246 Read article
-
Effect of Graphite and Titanium Dioxide on Mechanical Properties and Wear Behavior of Al based HMMCs
Abstract: Aluminium Metal Matrix Composites (MMC) is beneficial in a diversity of applications of engineering, particularly due to their strength while being lightweight. The intention of this paper is to develop a Hybrid Metal Matrix Composite (HMMC) using base metal aluminium alloy which is reinforced with different wt% of Graphite and Titanium Dioxide and then study the different mechanical properties like microstructure analysis, tensile strength, hardness, and wear behavior of HMMC …
Published in Journal of Polymer & Composites · Vol. 11, Issue 13, 2023 · pp. 20–30 Read article
-
Measurement of Urbanization in India: An Empirical Study Through Degree and Rate of Urbanization
Abstract: Urbanization is a progressive concentration of people in urban areas. Quantifying urbanization is a very challenging task. There are numerous demographic dimensions that can be used to quantify the urbanization process, among which the degree of urbanization and rate of urbanization are applied. Goal: Using Indian Census data from 1901 to 2011, this paper attempts to quantify the extent and pace of urbanization in India. The study is descriptive in …
Published in OmniScience: A Multi-disciplinary Journal · Vol. 14, Issue 1, 2024 · pp. 80–85 Read article
-
Pregnancy Outcomes on Chronically Hemodialyzed Women in Arab World: A Systematic Review
Abstract: Pregnancy carries a major risk of difficulties, as highlighted by the present systemic study on pregnancy outcomes in persistently hemodialyzed women in the Arab world. The objective of this systematic review was to describe the pregnancy outcomes among chronically hemodialyzed pregnant women in Arab countries in terms of the incidence of pregnancy among women on maintenance hemodialysis and the incidence of maternal and fetal complications of pregnant women on hemodialysis. …
Published in International Journal of Midwifery Nursing And Practices · Vol. 2, Issue 1, 2024 · pp. 25–36 Read article
-
Considerations on Fractured Edge Dislocations of Mechanical Tested Hand Laid Hemp Flax GFRP Hybrid Polymer Composites with SEM Verifications
Abstract: In this research study, three types of composite samples are made. Hemp-Glass Fiber (C1), Flax- Glass Fiber (C2), and Hemp-Flax-Glass Fiber Hybrid Composite (C3). For proper fibre-to-fiber adhesion and bonding, a 10:1 mixture of glue (LY556) and brace (HY951) was used. Tensile, flexural, impact, double shear, and hardness research is conducted among all the specimen samples. According to ASTM standards, the comparison is made among C1, C2 and C2 respectively; …
Published in Journal of Polymer & Composites · Vol. 11, Issue 13, 2023 · pp. 1–19 Read article
-
Experimental Investigation on Heat Transfer Characteristics of Thermal Barrier Coating on Aero Engine Components
Abstract: The gas turbine blades play a crucial role in harnessing energy from the high-temperature and highpressure gas generated by the combustor. To withstand this challenging environment, turbine blades often employ super-alloys and incorporate new manufacturing technologies such as Direct Solidification (DS) and Single Crystal (SC). Additionally, the development of advanced ceramic Thermal Barrier Coating (TBC) is imperative to achieve higher operating temperatures (>1200°C). Therefore, the primary focus of this study …
Published in Journal of Polymer & Composites · Vol. 11, Issue 13, 2023 · pp. 50–58 Read article
-
Coronary Vascular Disease: A General Review with Specific Reference to Etiology
Abstract: Cardiovascular disease (CVD), the foremost cause of mortality worldwide, has surged by 60% globally, reaching 20.5 million deaths in 2021 from 12.1 million in 1990, as per the latest report from the World Health Federation. While this increase is alarming on a global scale, it raises even greater concerns in countries like India where heart ailments are afflicting individuals at a younger age. The escalation of CVD among the younger …
Published in International Journal of Biomedical Innovations and Engineering · Vol. 2, Issue 1, 2024 · pp. 36–42 Read article
-
Formation, Characterization and Microscopic Study of Four- and Five-membered Ring
Abstract: Types of organic compounds are famous for many industrial and medical applications, including azo compounds, one of the largest groups involved in the manufacture of various organic compounds. For example, they are considered as initiators of free radicals in the polymerization reactions of alkenes used in the manufacture of plastics. Most of cyclic compounds have nano properties which make this type of compound important in organic field. It is also …
Published in OmniScience: A Multi-disciplinary Journal · Vol. 14, Issue 1, 2024 · pp. 1–15 Read article
-
Development and Assessment of Levetiracetam Microspheres Utilizing Synthetic and Natural Polymers: A Biomedical Engineering Perspective
Abstract: In the present study, comparative study of Levetiracetam loaded microspheres using Ethyl cellulose as synthetic and Sodium alginate as natural polymers was done. Solvent evaporation and ionic gelation technique has been successfully employed to produce Levetiracetam loaded ethyl cellulose and sodium alginate microspheres with optimal drug encapsulation that sustained the drug release over a period of time. Based on the pre-formulation studies E1 to E4 and S1 to S4 batches …
Published in International Journal of Biomedical Innovations and Engineering · Vol. 2, Issue 1, 2024 · pp. 1–18 Read article
-
Assessing Vitamin D Levels in Fortified Foods and Supplements for Infants and Its Impact: A Review
Abstract: In this study, the vitamin D levels in fortified foods (including follow-on formula, baby porridge, and curd cheese dessert) and dietary supplements designed for infants were examined. Analytical assessments uncovered variations in vitamin D concentrations compared to the labeled values, fortified foods contain anywhere from 50% to 153% for supplements 8% to 177%. Instant follow-on formula and oil-based supplements typically aligned with or surpassed the labeled values, whereas ready-to-eat baby …
Published in International Journal of Nutritions · Vol. 1, Issue 1, 2024 · pp. 19–24 Read article