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1696 articles for “fins” (ranking capped at the first 2,000 matches — narrow the search to see the rest)
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Prediction of Molecular Targets for Anthraquinone and Its Analogs for Treatment of Good Pasteur Syndrome
Abstract: Objective: In order to find prospective molecular targets for the treatment of Good Pasteur Syndrome (GPS), a rare autoimmune disease that affects the kidneys and other organs, computational methods and network pharmacology were applied in this work. The goal of the study is to identify particular human proteins that might interact with anthraquinone and its analogues as well as to uncover potential mechanisms of action by which these drugs might …
Published in International Journal of Bioinformatics and Computational Biology · pp. 10–27 Read article
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Network Pharmacology and Molecular Docking Approach to Reveal the Underlying Mechanisms of Isorhamnetin in the Treatment of Lymphangitis Carcinomatosis
Abstract: Objective: Lymphangitic carcinomatosis (LC) is a tumor that spreads through lung lymphatics and is most commonly seen secondary to adenocarcinoma. In the majority of cases, LC is a result of tumor cells spreading through the lymphatic system. However, approximately 20% of LC cases can be attributed to lymphangitis caused by tumors obstructing lymphatic drainage. This blockage commonly occurs near the lung hilum, where a centrally located mass can cause inflammation …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 1, Issue 1, 2023 · pp. 28–45 Read article
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Pharmacoinformatic Based Screening Of Phytocompound Epigallocatechin Gallate To Identify As A Potential Bcl-2 Inhibitor
Abstract: Objectives: The B-cell lymphoma-2 (Bcl-2) is a protein that is particularly though to be involved in preventing apoptosis. Bcl-2 family members also essential for cancer survival, and its over expression has been linked to tumor genesis, development and resistance to anticancer treatments. The Bcl-2 family of members that inhibit apoptosis is a promising target for the creation of anticancer drugs. Methods: The study was based on computational approach using different …
Published in International Journal of Bioinformatics and Computational Biology · pp. 1–13 Read article
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To evaluate the effectiveness of a structured educational program on knowledge about hypoglycemia and its management among diabetes patients living in selected urban slums of Durgapur, West Bengal
Abstract: INTRODUCTION: Diabetes Mellitus (DM) is a significant global health issue characterized by chronic hypoglycemia and an imbalance in the metabolism of carbohydrates, fats, and proteins. It has multiple underlying causes. Hyperglycemia refers to high blood glucose levels, while low blood glucose levels are known as hypoglycemia. Raising awareness about the signs and symptoms of diabetes among individuals with the condition can potentially minimize complications. OBJECTIVES: 1. To evaluate the initial …
Published in International Journal of Community Health Nursing And Practices · Vol. 1, Issue 1, 2023 Read article
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Optimization of Window Sizes based on Different Climatic Conditions
Abstract: Different climatic conditions have an impact on a building's performance. Climate-related factors will also affect how energy-efficient a structure is. As a result, making comparisons between buildings in various climate zones will produce inappropriate results. It is crucial to understand how much a building's energy performance can vary depending on the climate. By running energy simulation on the typical building, the climatic condition ratio is established for various climate zones …
Published in International Journal of Environmental Planning and Development Architecture · Vol. 1, Issue 1, 2023 · pp. 33–43 Read article
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A Study to Assess the Existing Hand Washing Practices with Soap and Water Among Women at Critical Times in Selected Families of (Kitte 1-7) Field Practice Area of Community Medicine, SGRD, Vallah, Amritsar
Abstract: Handwashing is the most important thing to prevent and control the illness and avoid the spread of disease. There is greater need regarding awareness of handwashing at critical times to reduce the prevalence of infections and from communicable diseases. However, there is a proper method to ensure all bacteria are removed. It is a technique of rubbing the hands together for a given period of time with soap and water. …
Published in International Journal of Emergency and Trauma Nursing and Practices · Vol. 1, Issue 1, 2023 · pp. 1–6 Read article
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To Assess the Effectiveness of Structured Teaching Program on Nosocomial Infection and Its Prevention Among Staff Nurses Working in Shri J.G. Co-Operative Hospital Society, Ghataprabha, Karnataka
Abstract: Aims: To evaluate staff nurses’ knowledge of nosocomial infections. To examine the impact of a systematic teaching curriculum on staff nurses’ ability to avoid nosocomial infections. Furthermore, to ascertain the relationship between staff nurse pre-test knowledge and specific demographic factors. Methods: In order to investigate and evaluate the staff nurses’ level of knowledge regarding nosocomial infection prevention, an evaluatory research approach was used for this study. Pre-experimental design was determined …
Published in International Journal of Evidence Based Nursing And Practices · Vol. 1, Issue 1, 2023 · pp. 8–11 Read article
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Knowledge and attitude of postnatal mothers towards Human Breast Milk Banking in a selected Hospital
Abstract: Background: Breast milk is universally endorsed as unique, innate and vital feed, gifted by nature for neonates. Human Breast milk banks function as stockpile for women who are incapable to provide their own breast milk to their unwell or confined infants. In Indian scenario, donation of breast milk is an emerging notion and has been introduced among few metropolises across the nation. Unavailability to breastmilk foster infants more susceptible to …
Published in International Journal of Midwifery Nursing And Practices · Vol. 1, Issue 2, 2023 · pp. 10–18 Read article
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Cross-layer Solutions in WSN Routing: A Review
Abstract: WSN is a less infrastructure wireless network which is embedded with large number of Sensor Nodes (SN). Its ad-hoc manner of device distribution allows it to monitor conditions under physical and environmental scenarios. Typically, SNs in WSN are installed in a specified geographical location to monitor required information. Due to SNs’ self-configuring ability, the exploitation of target is simpler. Though, its functioning is limited with factors such as energy efficiency, …
Published in International Journal of Wireless Security and Networks · Vol. 1, Issue 2, 2023 · pp. 26–36 Read article
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Drugs for Alzheimer’s Disease from Salix Alba Discovered Computationally Utilizing Virtual Screening and Docking against 1b41 Protein
Abstract: Objective : The of this research is to evaluate the feasibility of using molecular docking techniques to identify novel acetylcholinesterase, a key enzyme implicated in the pathogenesis of Alzheimer’s disease, a neurodegenerative disorder with a gradual but steady progression to death, due to the gradual accumulation of beta-plaques and neurofibrillary tangles, as well as a decline in acetylcholine levels. Due to its function in converting acetylcholine into acyl and choline …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 1, Issue 2, 2023 · pp. 07–19 Read article
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Effect of Mindfulness-Based Yoga Practices on Anxiety and Attention Level Among High School Children in a Selected High School, Bhubaneswar, Odisha
Abstract: Background: In a world filled with endless pressures and expectation, school-aged children often find themselves navigating through a labyrinth of stressors and anxiety. from the moment they wake up their tiny minds are bombarded with worries about exams, social interaction.it is in these moments of chose that the ancient practice of yoga emerges as a gentle beacon of hope, offering solace and tranquility to these young souls. The study main …
Published in International Journal of Evidence Based Nursing And Practices · Vol. 1, Issue 2, 2023 · pp. 1–8 Read article
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A Review of the Properties of Electro Less Duplex Coatings with Different Outer Layers and Bath Preparations
Abstract: Electroless coatings are widely used now because of their outstanding tribological as well as physical qualities. The need for a coating or finished product with any of these attributes has increased over the past few years. As a consequence, there has been a rise in the amount of study and associated publishing production on the creation of various surface types and coverings with various components. This study gave rise to …
Published in International Journal of Electro-Mechanics and Material Behaviour · Vol. 1, Issue 1, 2023 · pp. 6–11 Read article
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Effect of Energy, Lysine and Energy/Lysine Ratio on Growth Performance Nutrient Digestibility and Serum Profile of Growing Locally Adapted Turkey
Abstract: This study investigated the effects of different levels of energy, lysine and energy/lysine ratios on growth performance, nutrient digestibility, and serum biochemical indices of locally adapted turkeys. The experiment lasted for 28 days. A total of one hundred and forty-four, 4-weeks old locally adapted turkey poults were completely randomized to six dietary treatments in a 2×3 factorial arrangement, replicated twice at 12 poults per replicate. Six diets were formulated. Diets …
Published in International Journal of Biochemistry and Biomolecule Research · Vol. 1, Issue 1, 2023 · pp. 01–08 Read article
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Design and Simulation of Low-power, High-speed Effective Area Mux Based One-bit Full Adder Using CMOS Technology
Abstract: Our findings reveal a novel kind of circuit capable of performing both XOR and XNOR operations in parallel. Power dissipation and delay are both greatly reduced in the proposed circuits due to their low output capacitance as well as minimal short-circuit power dissipation. We show six new hybrid 1-bit full-adder (FA) circuits that take use of the XOR-XNOR or XOR/XNOR gates' special full-swing function. Each potential circuit layout has both …
Published in International Journal of VLSI Circuit Design & Technology · Vol. 1, Issue 1, 2023 · pp. 25–33 Read article
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Design and Development of Ankle Foot Orthosis for Foot Amputated Person by Using Carbon Fibre
Abstract: Ankle and foot orthotics play a pivotal role in the rehabilitation of individuals who have suffered a stroke, aiding in the restoration of their gait and overall mobility. However, optimizing the effectiveness of these orthoses requires a personalized approach that takes into account each patient's unique biomechanical characteristics. This study delves into the innovative use of carbon fiber combined with cost-effective 3-D printing technology to craft custom foot plate orthoses …
Published in Journal of Polymer & Composites · Vol. 11, Issue 8, 2023 · pp. 115–121 Read article
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Assessment of the Impact of a Structured Educational Program on PCOS Knowledge Among Adolescent Girls in a Chosen Area of Tarn Taran District, Punjab
Abstract: Polycystic ovary syndrome (PCOS) is a health condition characterized by elevated levels of androgen hormones, irregular menstrual patterns, and the existence of small cysts on one or both ovaries. The disorder can be morphological or biochemical. Prevention of PCOS includes lifestyle modifications that are to manage weight, exercise, and dietary changes. Aim and Objectives: The main goal of this study was to assess the efficacy of a structured educational program …
Published in International Journal of Women's Health Nursing And Practices · Vol. 1, Issue 2, 2023 · pp. 36–41 Read article
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Noise Pollution in Healthcare Settings: Impacts on Patient Recovery and Staff Well-Being
Abstract: Healthcare environments frequently experience noise pollution, which has serious effects on both patient recovery and the well-being of healthcare staff. This extensive research study includes patient rooms, waiting spaces, and corridors as part of its effort to measure and categorize noise levels. The study explores the complex effects of noise pollution on patients and healthcare personnel by integrating quantitative measures, surveys, and qualitative evaluations. According to preliminary research, loud surroundings …
Published in International Journal of Environmental Noise and Pollution Control · Vol. 1, Issue 1, 2023 · pp. 19–24 Read article
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Tinospora Sinensis Compounds for Zika Virus Targets 5JRZ and 5KVD In Silico Screening: A Potential Approach to Preventing Guillain-Barre Syndrome
Abstract: Objective: GBS is a very rare kind of disease but at the same time, it is very dangerous too. The study estimates that people who are suffering from zika virus infection are more prone to GBS. According to surveys, 1 out of 4000 people got affected by this disease, and the scariest part of this disease is that there is no cure available. In this computational era drug discovery is …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 1, Issue 2, 2023 · pp. 1–15 Read article
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Design and Development of Additive Manufacturing Machine
Abstract: Rapid prototyping, commonly referred to as 3D printing or additive manufacturing (AM), is the process of creating three-dimensional objects by layer-by-layer addition of material. It is very different from subtractive and conventional forming techniques. The goal of this special issue is to gather research and advancements in additive manufacturing (AM), with an emphasis on novel manufacturing techniques and substitute products and materials for feedstock. Although metal and polymer-based materials have …
Published in International Journal of Electrical Power and Machine Systems · Vol. 1, Issue 1, 2023 · pp. 1–7 Read article
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Effect of Energy/Protein Ratio and Strain on Performance, Nutrient Digestibility and Serum Biochemical Indices of Exotic and Locally Adapted Turkey
Abstract: This study investigated the response of locally adapted and exotic turkeys raised under the same environmental conditions to diets with varying energy/protein ratio. One hundred and fourty-four (144) four-week old poults of each strain of turkey were randomly selected and assigned to six different diets in a 2 x 2 x 3 factorial arrangement. Each treatment diet were replicated twice with twelve (12) birds per replicate. Diets formulated with 28 …
Published in International Journal of Biochemistry and Biomolecule Research · Vol. 1, Issue 2, 2023 · pp. 37–45 Read article