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87 articles for “pH-responsive polymers”
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Nanoparticle and Lipid-Based Vaccine Delivery Systems: A Systematic Review of Platforms, Stability, Pharmacokinetics, and Immune Modulation
Abstract: The rapid evolution of vaccine technologies over the past decade has highlighted the transformative role of nanoparticle (NP) and lipid-based delivery systems in modern immunization practices. These platforms – including polymeric nanoparticles, lipid nanoparticles (LNPs), liposomes, nanoemulsions, and solid lipid nanoparticles (SLNs) – enable enhanced antigen stability, improved cellular uptake, targeted antigen delivery, and potent immune activation. This systematic review critically examines the physicochemical foundations, manufacturing approaches, stability challenges, pharmacokinetic …
Published in Research and Reviews: A Journal of Toxicology · Vol. 16, Issue 1, 2026 · pp. 18–36 Read article
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Microsphere-Based Drug Delivery: A Critical Review of Innovations and Applications
Abstract: Microspheres have emerged as a revolutionary approach in pharmaceutical sciences, offering controlled and targeted drug delivery with improved bioavailability, stability, and patient compliance. These spherical carriers, ranging from nanometers to micrometers in size, can encapsulate both hydrophilic and hydrophobic drugs, enabling sustained and site-specific release. The development of microspheres has been significantly driven by the need to enhance drug efficacy while minimizing systemic side effects. This review provides a comprehensive …
Published in Trends in Drug Delivery · Vol. 12, Issue 2, 2025 · pp. 52–59 Read article
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A Comprehensive Review on Nanostructured Polymer Composites for CT Imaging Contrast Enhancement in Brain Tumor Diagnosis
Abstract: The detection and characterization of brain tumors require high-resolution and non-invasive imaging modalities that have the ability of differentiating tumorous tissues and healthy brain tissues. Computed tomography (CT) can be included in this number because, in addition to providing speedy scans and penetration to deep tissue, the diagnostic capability in soft tissue organ such as the brain is poor despite low natural contrast. The review is dedicated to the emerging …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 148–162 Read article
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Comprehensive Review on Pulsatile Drug Delivery System: Hybrid Approaches
Abstract: Pulsatile drug delivery systems (PDDS) represent a groundbreaking approach in pharmaceutical technology, allowing for controlled, targeted, and programmable drug release that aligns with circadian rhythms or caters to time-sensitive therapeutic requirements. Although traditional pulsatile systems have shown considerable clinical promise, their effectiveness is frequently compromised by physiological variations such as gastrointestinal transit times, changes in pH, and enzymatic activity. To tackle these obstacles, hybrid PDDS have been developed by combining …
Published in Trends in Drug Delivery · Vol. 13, Issue 1, 2026 · pp. 18–31 Read article
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Fabrication and Testing of Physical Behavior of Coconut Shell Micro Particulate and Walnut Shell Micro Particulate Reinforced Epoxy Composites
Abstract: Enhancing the physical characteristics of high-performance materials is largely dependent on the reinforcement of polymers by microparticles. The physical behavior of polyester composites containing coconut and walnut shell microparticles was thus investigated in order to create an engineering material for industrial use. Most researchers investigated the flammability test of fiber bio-composites only. There is a possibility that two particular polymers embedded in a thermoset polymer matrix could provide the lowest …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 592–603 Read article
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Nano‑Enabled CT for Cancer Imaging: From Molecular Targeting to Image‑Guided Therapy
Abstract: Nano‑enabled computed tomography (CT) exploits high‑atomic‑number (high‑Z) nanomaterials engineered with targeting ligands and therapeutic payloads to enhance contrast, enable molecular imaging, and support image‑guided interventions in oncology. Tumor‑specific nanoprobes such as RGD‑modified gold nanorods, polymer‑coated bismuth nanoparticles, and peptide, antibody, or aptamer‑functionalized platforms can intensify tumor conspicuity, allow early lesion detection and staging, and provide real‑time treatment monitoring. Integration of CT visibility with photothermal, photodynamic, chemo‑, radio‑, and immunotherapeutic functions …
Published in Nano Trends – A Journal of Nano Technology & Its Applications · Vol. 28, Issue 1, 2025 · pp. 40–49 Read article
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Artificial Intelligence Techniques for Smart Polymer Nanocomposite Materials and Industrial Applications
Abstract: Protecting sensitive material data, manufacturing processes, and intelligent monitoring platforms is essential for the fast development of innovative polymer nanocomposite systems in fields such as aerospace, medicine, electronics, automobiles, and energy. In order to safeguard, consistently enhance, and optimize distributed industrial systems that consist of polymer nanocomposite materials, this study presents an AI-driven cybersecurity and cloud computing architecture. The suggested solution employs artificial intelligence (AI), machine learning (ML), cloud computing, …
Published in Journal of Polymer & Composites · Vol. 14, Issue 3, 2026 Read article
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Electroactive Graphene–Polymer Nanocomposites for Self-Sustaining and Multifunctional Flexible Devices
Abstract: Graphene–reinforced polymer–composites were developed and systematically investigated to explore their multifunctionality in flexible electronic applications. The study specifically aims to correlate graphene-induced structure–property–function relationships with electroactive performance and self-sustaining behaviour in flexible devices. The hybridization of electroactive polymers—polyaniline (PANI), poly(3,4-ethylenedioxythiophene): polystyrene sulphonate (PEDOT:PSS), and polyvinylidene fluoride (PVDF)—with graphene nanoplatelets enabled simultaneous enhancement of electroactivity, energy-harvesting, and sensing functionalities. Morphological studies confirmed uniform graphene dispersion at 5 wt.% loading, forming continuous …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 260–271 Read article
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Effect of Surface Modification on Properties of Kevlar/Epoxy Polymer Composites
Abstract: In this study, a high-performance Kevlar/epoxy polymer composite was prepared using a hand lay-up technique. The Kevlar fiber was treated with calcium chloride/ethanol solution (CaCl2/EtOH) to enhance the interfacial interaction between the fiber and the epoxy matrix. The optimization of fiber surface treatment and fiber content for the best tensile strength (TS) of Kevlar/epoxy polymer composite was achieved using Box-Behnken design (BBD) through response surface methodology (RSM). Three parameters: CaCl2 …
Published in Journal of Polymer & Composites · Vol. 13, Issue 2, 2025 · pp. 35–46 Read article
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Interfacial Engineering of Carbon Fiber/Epoxy Laminates Using Functionalized Graphene Nanoplatelets: Experimental and Numerical Study
Abstract: Current research work studies the influence of amines(–NH₂) and carboxyl(–COOH) functionalized graphene nanoplatelets on the mechanical and thermomechanical behavior of unidirectional hybrid composite. Composites having different graphene concentration from 0 to 0.7 wt% were fabricated, characterized and analyzed for multiple testing - tensile testing, dynamic mechanical analysis (DMA) and Fourier transform infrared spectroscopy (FTIR). Tensile testing indicates better elastic modulus and tensile strength due to efficient load transfer between nanoparticles …
Published in Journal of Polymer & Composites · Vol. 14, Issue 3, 2026 · pp. 61–77 Read article
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Biomedical Coatings: Surface Engineering for Enhanced Biocompatibility and Performance
Abstract: Biomedical coatings have become essential in modern healthcare, significantly improving the performance, durability, and biocompatibility of medical implants and devices. These coatings serve multiple functions, including reducing infection risks, enhancing osseointegration, promoting tissue integration, and enabling localized drug delivery. Advances in surface engineering have led to the development of innovative coatings with superior properties such as antimicrobial resistance, bioactivity, and controlled biodegradation. Various materials are employed in biomedical coatings, including …
Published in Journal of Thin Films, Coating Science Technology & Application · Vol. 12, Issue 1, 2025 · pp. 8–15 Read article
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Comprehensive Review of Nanomaterials Synthesis Methods, Characterization and Multifaceted Applications in Medical Field
Abstract: Nanomaterials associated by special qualities derived from their nanoscale size nanomaterials have tremendous potential in a variety of industries like, medicine & healthcare. Due to today busy life & unhealthy life schedule many abnormal cell growth take place in our body & affect the other organ. Sometimes it may leads to cancer & others dangerous diseases, nanomaterials such as nanotubes, liposomes & polymeric micelles are help for designing the drugs …
Published in Journal of Polymer & Composites · Vol. 13, Issue 5, 2025 · pp. 657–669 Read article
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Copper Sulfide Semiconducting Nanoparticles for Antibacterial Applications: Synthesis Strategies, Mechanisms and Performance – A Review
Abstract: Copper sulfide nanoparticles (CuS NPs) have drawn growing attention as a next-generation antibacterial platform, owing to their tunable structural, optical, and catalytic properties. This review consolidates current evidence on CuS NP synthesis, mechanisms, and antibacterial performance, comparing chemical and green synthesis routes alongside the effects of morphology, doping, and surface modification. Mechanistically, CuS NPs act through several overlapping pathways, including reactive oxygen species generation, bacterial membrane disruption, ion release, and …
Published in Journal of Polymer & Composites · Vol. 14, Issue 4, 2026 Read article
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Greener 3D Printing: The Role of Artificial Intelligence in Sustainable Polymer and Composite Manufacturing
Abstract: The integration of sustainable materials with additive manufacturing (AM) technologies marks a significant step towards environmentally responsible production. Biodegradable polymers, recycled thermoplastics, and bio-based composites, when used in 3D printing, offer the potential to reduce the ecological footprint of manufacturing. However optimizing the interplay between material properties process parameters, and product performance remains a complex challenge. This review examines how artificial intelligence (AI) is being applied to address these challenges …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 288–300 Read article
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Biopolymer Degradation and Structure–Property Relationships in Ageing: A Polymer Science Perspective
Abstract: Ageing, as viewed from the polymer sciences perspective, is perceived as the gradual modification of the structure-property-function interrelationship of biopolymers such as proteins, polysaccharides, nucleic acids and their molecular aggregates. Such changes include structural organization, mechanical behavior, physicochemical stability and functional effectiveness. Ageing is an inevitable multifactorial polymeric process. Due to the growing aging population globally, more age-associated complications emerge, which are correlated with the molecular degeneration of biopolymeric complexes. …
Published in Journal of Polymer & Composites · Vol. 14, Issue 3, 2026 · pp. 479–489 Read article
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Sustainable Membrane Fabrication Using Green Chemistry Principles: A Comprehensive Review of Microwave Irradiation, Sonochemical, and Continuous Flow Methodologies
Abstract: Membrane-based separation technologies have emerged as indispensable tools in water purification, biomedical engineering, pharmaceutical processing, and environmental protection. However, conventional membrane fabrication processes often rely on hazardous organic solvents, energy– intensive steps, and environmentally taxing conditions. In response to increasing global emphasis on sustainability and regulatory pressures, green chemistry strategies have gained attention for enabling safer, energy-efficient, and eco-friendly membrane production. This review provides a comprehensive and structured analysis of …
Published in International Journal of Membranes · Vol. 3, Issue 1, 2026 · pp. 8–24 Read article
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Biodegradable Polymer Nanocarriers Composites for Biomedical Applications
Abstract: Smart polymeric nanocarriers, or SPNs, have evolved into a fascinating means of delivering medications especially to cancer cells. By improving the efficacy of chemotherapeutic treatments while lowering their negative effects, they have achieved a significant progress in exact medicine. Made to respond to certain elements in the tumours microenvironment, such as enzymes, temperature, pH, and redox conditions, these nanocarriers this reaction to triggers guarantees the release of the medicine at …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 293–305 Read article
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Green Synthesis and Functional Evaluation of Ag–Polypyrrole/TeO2 Nanocomposites for Advanced Electronic Applications
Abstract: Ag–PPy/TeO₂ nanocomposites with TeO₂ loadings ranging from 2% to 10% were synthesized using an in-situ chemical polymerization method. Green tea extract, rich in phytochemicals, acted as both a reducing and stabilizing agent to facilitate the formation of metal oxide nanoparticles. The structural and morphological characteristics of the nanocomposites were analyzed using FTIR, PXRD, and SEM techniques. FTIR confirmed the successful integration of Ag, TeO₂, and PPy functional groups. PXRD patterns …
Published in Journal of Polymer & Composites · Vol. 14, Issue 2, 2026 · pp. 64–76 Read article
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An Optimize Formulation to Synthesis of size Controlled Hydrophobic Starch Acetate Nanoparticles using Box- Behnken Design
Abstract: The best way to improve the overall performance of native starch is by chemical modification. In recent years, hydrophobically modified starch has attracted considerable attention for the design and manufacture of novel nanoparticulate drug delivery carriers. The purpose of this research was to synthesize hydrophobic starch nanoparticles (NPs) and to optimize process factors through the use of response surface methodology (RSM). The corn starch acetate (CSA) NPs was synthesized using …
Published in Journal of Polymer & Composites Read article
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Fluid Dynamics of a Stressed Freshwater Lens: Integrated Flow Modeling and Pathways for Material-Centric Interventions in Khadir Island, Gujarat
Abstract: This study applies principles of fluid dynamics and porous media mechanics to analyze the behavior and sustainability of the freshwater lens in Khadir Island, an arid sedimentary island in Gujarat, India. We develop an integrated fluid flow model that couples surface hydrology with aquifer dynamics to quantify recharge fluxes, extraction stresses, and hydraulic responses. Using 11-year hydro-meteorological data (2011–2021) and sectoral demand projections, we characterize the island’s water budget through …
Published in Journal of Polymer & Composites · Vol. 14, Issue 2, 2026 · pp. 12–29 Read article