Search
231 articles for “mechanical integrity”
-
Nutrition Induced Remodeling Dynamics of Cell Membranes: Implications for Performance, Health, and Welfare Issues in Food Animals
Abstract: Cell membranes represent dynamic structural and functional platforms that integrate nutritional signals with cellular metabolism, immune competence, and physiological adaptation in food animals. Beyond their classical role as selective barriers, membranes actively regulate nutrient transport, signal transduction, and bioenergetics through highly responsive lipid and protein networks. Dietary components, particularly fatty acids, vitamins, minerals, amino acids, and bioactive compounds, critically influence membrane composition, fluidity, and stability, thereby shaping cellular function and …
Published in International Journal of Membranes · Vol. 3, Issue 1, 2026 · pp. 25–37 Read article
-
Smart Air Filtration Systems for Cities: A Technological Approach to Reducing Urban Pollution
Abstract: Urban air pollution is considered one of the main ecologically critical issues of the 21st century since it threatens citizens' health through respiratory diseases, pathologies of the cardiovascular system, and even premature death. Regarding an extremely high level of pollution in large cities, it becomes necessary to realize technological solutions which could avoid the negative impact of this phenomenon. Smart air filtration systems have emerged as promising solutions for urban …
Published in International Journal of Environmental Noise and Pollution Control · Vol. 2, Issue 2, 2024 · pp. 27–42 Read article
-
The Intersection of Bioinformatics and Cellular Function in Disease Modeling
Abstract: The integration of bioinformatics and cellular biology has revolutionized our understanding of disease mechanisms, offering unprecedented opportunities to model complex biological systems. Bioinformatics is an interdisciplinary field that merges biology, computer science, and statistics, offering advanced tools to analyze vast biological datasets. Cellular functions, including gene expression, protein interactions, and metabolic pathways, form the foundation of physiological and pathological states. Disruptions in these processes can result in diseases like cancer, …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 2, Issue 2, 2024 · pp. 1–7 Read article
-
Nutrition Induced Gut Microbiota Modulation in Food Animals: Implications for Viral Susceptibility, Shedding and Transmission Dynamics for Sustainable Development
Abstract: The gut microbiota has emerged as a central mediator linking host nutrition, immune competence, and vulnerability to viral pathogens in food animals. Diet is a primary driver of microbial community structure and function, influencing metabolite production, intestinal barrier integrity, and systemic antiviral immunity. Accumulating evidence indicates that nutrition induced modulation of the gut microbiota can substantially alter viral susceptibility, replication, and shedding patterns, with downstream effects on transmission dynamics within …
Published in International Journal of Virus Studies · Vol. 3, Issue 1, 2026 · pp. 46–56 Read article
-
A Constraint-Driven Generative Design Methodology for Modular Actuated Robotic Components in Decentralized Manufacturing
Abstract: This work formalizes a constraint-driven generative design framework for actuator-integrated robotic components intended for decentralized additive manufacturing. Conventional topology optimization typically prioritizes structural efficiency while treating actuator integration, modular interfaces, and fabrication constraints as secondary considerations. In contrast, the proposed methodology encodes these requirements as first-order geometric and mechanical constraints prior to automated material redistribution. The framework defines preserved actuator geometry, bounded design envelopes, representative loading abstractions, and manufacturability-aware domains …
Published in International Journal of Robotics and Automation in Mechanics · Vol. 4, Issue 1, 2026 Read article
-
Integrating Digital Twins, Smart Materials, and Human Machine Collaboration for Sustainable Smart Manufacturing: Smart CNC & Industry 4.0 Applications
Abstract: The rapid evolution of Industry 4.0 and the emerging transition toward Industry 5.0 have been catalyzed by the convergence of intelligent digital technologies such as digital twins, cyber–physical systems (CPS), artificial intelligence (AI), the Internet of Things (IoT), and human-in-the-loop (HITL) frameworks. These technologies have transformed traditional manufacturing into adaptive, data-centric ecosystems capable of real-time optimization and predictive decision-making. In recent years, the fusion of computer numerical control (CNC) machines, …
Published in International Journal of Manufacturing and Production Engineering · Vol. 3, Issue 2, 2025 · pp. 1–8 Read article
-
Fracture Analysis of Laminated composite plates using Extended Finite Element Method: A Review
Abstract: Laminated composite plates are used in aerospace, automotive, and marine industries. They feature great durability against fatigue, a high strength-to-weight ratio, and mechanical attributes that may be altered. However, they are prone to fracture and delamination under complex loading, requiring accurate fracture analysis for structural integrity. Traditional finite element methods (FEM) need extensive mesh refinement for modelling crack propagation which increases the computational costs. The Extended Finite Element Method (XFEM) …
Published in International Journal of Fracture Mechanics and Damage Science · Vol. 4, Issue 1, 2026 · pp. 16–25 Read article
-
Differential Privacy-Aware Data Sanitization for Multi-Level Security
Abstract: Multi-level security (MLS) models are fundamental for enforcing mandatory access control in high-security environments such as government, military, healthcare, and finance. However, traditional MLS frameworks, including the Bell-LaPadula and Biba models, often create rigid data silos, preventing efficient data utilization. Differential privacy (DP) presents a novel solution by enabling controlled information leakage while preserving confidentiality. By injecting statistical noise into query results, DP allows lower-clearance users to access sanitized versions …
Published in International Journal of Computer Science Languages · Vol. 3, Issue 1, 2025 · pp. 42–52 Read article
-
A Review Natural Ventilation by Using Solar Chimney
Abstract: A solar chimney is an effective and sustainable ventilation technology designed to enhance airflow within residential and commercial buildings by utilizing natural convection. Operating on principles like a traditional fireplace, a solar chimney harnesses solar energy to generate an upward air movement, creating a pressure difference that drives passive ventilation. The system comprises a vertical shaft, usually constructed with heat-absorbing materials, which captures solar radiation and heats the enclosed air. …
Published in International Journal of Electrical Power and Machine Systems · Vol. 3, Issue 1, 2025 · pp. 22–28 Read article
-
LoRa and LoRaWAN in the IoT: Performance, Challenges, and Future Opportunities
Abstract: This paper provides a broad overview of both LoRa and LoRaWAN technologies in the context of Internet of Things (IoT). The market need for communication technology to be low-power and long-range continues to grow, and LoRa and LoRaWAN are emerging as viable options for enabling widespread IoT applications in a variety of applications. This review offers structured and comparative assessment of their functionality in different environments, such as urban, rural, …
Published in International Journal of Wireless Security and Networks · Vol. 4, Issue 2, 2026 Read article
-
Non-Enzymatic Glycation in Alzheimer’s and Parkinson’s Disease: A Molecular Approach to Pathology and Recent Advances
Abstract: Non-enzymatic glycation, a biochemical process by which reducing sugars spontaneously bind to proteins, leads to the formation of advanced glycation end-products (AGEs), which have emerged as critical contributors to the pathogenesis of several neurodegenerative diseases, particularly Alzheimer’s disease (AD) and Parkinson’s disease (PD). The accumulation of AGEs can significantly alter protein structure, stability, and function, triggering a cascade of detrimental effects, including increased oxidative stress, heightened neuroinflammation, and the promotion …
Published in International Journal of Molecular Biotechnological Research · Vol. 2, Issue 2, 2024 · pp. 36–41 Read article
-
A Study on Automatic Feedback Control by Image Processing for Mixing Solutions in a Microfluidic Device
Abstract: Precise and rapid mixing of chemical and biological reagents is a critical yet challenging aspect of microfluidic systems, often limited by laminar flow conditions and the need for manual or pre- programmed interventions. Existing mixing strategies frequently lack real-time adaptability and closed-loop control, hindering reproducibility and the execution of complex reaction protocols. This work presents an innovative automatic feedback control system utilizing the study on real- time image processing to …
Published in International Journal of Advanced Control and System Engineering · Vol. 3, Issue 2, 2025 · pp. 32–41 Read article
-
Biological Membranes: Structure, Function, and Their Roles in Disease Pathophysiology
Abstract: Biological membranes are important structures that control cellular work, signal transmission, transport, and communication. Dysfunction of membranes has been considered in the development of many diseases, such as cancer, neurodegenerative diseases, and infections, with the distortion of lipid composition, protein activity, and cellular connections involved in the pathogenesis of the disease. The damage on membrane can be caused by oxidative stress, genetic mutation, and environmental influence to disrupt cellular homeostasis. …
Published in International Journal of Membranes · Vol. 3, Issue 1, 2026 · pp. 38–46 Read article
-
Integrating Network Pharmacology and Molecular Docking to Investigate Boerhavia diffusa for Pancreatic Cancer Treatment
Abstract: Objective: In this study, network pharmacology was applied to determine the therapeutic effects of the bioactive compounds of Boerhavia diffusa. Network pharmacology can unearth the underlying mechanisms between drugs and the disease targets and aids in the discovery of novel medications for complex conditions such as cancer. Methods: To predict the molecular mechanisms of action of Boerhavia diffusa in the treatment of was screened using the GeneCards database. The Venn …
Published in International Journal of Molecular Biotechnological Research · Vol. 2, Issue 1, 2024 · pp. 29–49 Read article
-
Integrating Network Pharmacology and Molecular Docking to Assess Rutin’s Pharmacological Properties
Abstract: Objectives: In the present research, the network pharmacology process was applied to determine the underlying mechanism of the pharmacological properties of Rutin. Network pharmacology was utilized to reveal the interactions between medications and the targets of illnesses, and it is capable of completely articulating the complexity between diseases and medications. The identification of diverse drug-target interactions using network pharmacology may be utilized to discover novel medications for difficult conditions like …
Published in International Journal of Molecular Biotechnological Research · Vol. 1, Issue 1, 2023 · pp. 20–33 Read article
-
Enhancing Road Safety: A System for Vehicular Accident Detection, Prevention, and Rescue Alerts
Abstract: The Vehicular Accident Detection, Prevention, and Rescue Alert System is a comprehensive solution aimed at bolstering road safety by integrating multiple advanced technologies. It merges drowsiness detection, alcohol level monitoring, and instant emergency alerts to mitigate accidents and expedite rescue efforts. Modern computer vision and machine learning techniques are used by the Drowsiness Detection Alarm to track driver conduct and spot drowsiness indicators. Upon detecting drowsiness, an immediate alarm is …
Published in International Journal of Solid State Innovations & Research · Vol. 2, Issue 2, 2024 · pp. 7–11 Read article
-
Design and Development of Multifunctional Stretcher
Abstract: Hospital stretchers and wheelchairs are integrated in this piece. Instead of using the chair and stretcher individually, the suggested stretcher can be utilized for multiple purposes. Patients' mobility issues can be greatly reduced by this arrangement. There is a challenge in the ICU moving seriously damaged or fractured patients from stretcher to wheelchair. This product is capable of addressing such situations. One more advantage of the proposed design to conduct …
Published in International Journal of Industrial and Product Design Engineering · Vol. 4, Issue 1, 2026 · pp. 29–34 Read article
-
Circadian Regulation of Lipid Peroxidation in the Brain: Linking Ferroptosis to Neurodegenerative Vulnerability
Abstract: The human brain operates through highly coordinated physiological and biochemical processes that regulate cognition, behavior, and neural adaptability. Central to these processes are mechanisms governing brain function, neurophysiology, and neuroplasticity, which are increasingly recognized to be influenced by circadian rhythms. Recent advances in cognitive neuroscience, neuroimaging, and behavioral neuroscience have revealed that disruptions in circadian regulation can significantly impact oxidative balance within the brain, particularly through enhanced lipid peroxidation. Lipid …
Published in International Journal of Brain Sciences · Vol. 3, Issue 2, 2026 · pp. 1–14 Read article
-
Complex Space-Time and the Structure of Relativistic Quantum Theory
Abstract: Relativistic quantum mechanics was developed to reconcile the principles of quantum mechanics with Einstein’s theory of relativity. Despite its success in describing high-energy particles, the theory continues to face unresolved conceptual and mathematical difficulties, particularly in relation to the nature of time, causality, and relativistic consistency. In recent years, the idea of extending space-time into the complex domain has emerged as a useful and potentially meaningful approach to these problems. …
Published in Recent Trends in Mathematics · Vol. 3, Issue 1, 2026 · pp. 22–27 Read article
-
Bridging the Gap Between Product Development and Entrepreneurship in Engineering Curriculum: A Framework-Based Approach Aligned with NEP 2020
Abstract: Despite advancements in technical education, Indian engineering graduates frequently enter the workforce lacking critical competencies in product development (PD) and entrepreneurship. This imbalance has drawn scrutiny from industry and policymakers alike, with national directives such as the National Education Policy (NEP 2020) emphasizing a shift toward “experiential, holistic, integrated and inquiry-driven” learning models. Similarly, the All-India Council for Technical Education (AICTE) has embedded innovation labs, internship mandates and entrepreneurship courses …
Published in International Journal of Education Sciences · Vol. 3, Issue 1, 2026 · pp. 87–100 Read article