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83 articles for “clinical isolates”
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How Scientists Look for New Pathogens Before They Spread
Abstract: Emerging infectious illnesses are a persistent danger to global health. They often come from unexpected places, such wildlife reservoirs, changes in the climate, or human activities. Finding new diseases before they create epidemics is one of the biggest problems in modern epidemiology. This article talks about how scientists use genetic monitoring, field sampling, and real-time data processing to find, track, and describe new infectious organisms in a way that works …
Published in International Journal of Pathogens · Vol. 3, Issue 1, 2026 · pp. 11–17 Read article
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Phytochemical Investigation, Safety and Efficacy Evaluation of Calpurnia aurea (ssps): Commonly Used Traditional Medicinal Plant in Ethiopia: A Compressive Review
Abstract: In Ethiopia, Calpurnia aurea (digita), a traditional medicinal plant is used for the treatment of syphilis, malaria, rabies, diabetes, hypertension, diarrhoea, leishmaniasis, trachoma, elephantiasis, fungal diseases and different other ailment of human and animals. It is important to find a scientific evidence for the traditional use and standardization of the medicinal plant to ensure safety, efficacy and quality through preliminary phytochemical screening, analysis, safety and efficacy studies. Based on this …
Published in Research & Reviews : Journal of Herbal Science · Vol. 9, Issue 3, 2020 · pp. 23–31 Read article
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Phyto-bioefficiency of Vijaya Extract for Normal Cell Protection and Its Anticancer Efficiency Against Breast Cancer Xenograft
Abstract: Cannabis is an annual, dioecious, flowering herb. Its leaves are palmately compound by serrate leaflets. Cannabis sativa maximum phytochemicals are soluble in organic solvent. The Cannabis plant has been historically used due to its medicinal properties since thousands of years through several beliefs. In India, the department of narcotics has sanction that Cannabis can be grown in a monitored way with proper approval and license. The present study concludes that …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 11, Issue 3, 2022 · pp. 15–21 Read article
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The Quiet Intruder: An Insidious Presentation of Primary Plasma Cell Leukemia and a Literature Review on Current Treatment Strategies
Abstract: Introduction: Primary plasma cell leukemia (pPCL) is a rare and aggressive plasma cell dyscrasia, defined by ≥5% circulating plasma cells, with poor prognosis and rapid progression. Case Presentation: A 66-year-old African–American female with no prior medical history presented with one week of fatigue, dehydration, and polydipsia. Laboratory evaluation revealed leukocytosis, severe thrombocytopenia, acute kidney injury (creatinine 4.03 mg/dL), and hypercalcemia (13.0 mg/dL) with suppressed PTH. Imaging showed intra-abdominal lymphadenopathy without …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 15, Issue 2, 2026 · pp. 1–5 Read article
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Anticancer Potential and Other Therapeutic Activities of Curcumin & Its Derivatives
Abstract: Curcumin, a compound isolated from turmeric, is used in the management of various diseases due to its extensive medicinal properties. Curcumin, the principal polyphenol isolated from Curcuma longa (turmeric), has garnered immense scientific interest for its extensive medicinal properties, including potent anti-inflammatory, antioxidant, and anticancer activities demonstrated in preclinical models. An expanding body of research indicates broad therapeutic promise in managing diverse pathologies, from various cancers to chronic inflammatory, metabolic, …
Published in Emerging Trends in Metabolites · Vol. 3, Issue 1, 2026 · pp. 19–28 Read article
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Documentation in Ayurvedic Clinical Practice: Present Scenario
Abstract: AbstractAyurveda is a science which is practiced since centuries. It is not only limited to Ayurvedic hospitals/clinics and pharmacies on a small/large scales. In spite of this long-term use, there are several issues in Ayurveda which cause some concerns globally as well as locally in India, regarding its usefulness and safety. One of the reasons for this in spite of its long-term use is lack of systematic documentation and scientific …
Published in Research & Reviews : Journal of Herbal Science · Vol. 3, Issue 2, 2014 · pp. 11–16 Read article
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SkinSight: Design and Implementation of an Intelligent Skin Type Detection System
Abstract: Identifying an individual’s skin type accurately is essential for creating personalized dermatological treatments and formulating skincare products that genuinely meet user needs. In this project, a real- time skin type classification system is developed using a combination of convolutional neural networks (CNNs) and modern computer vision techniques. The system processes live video streams, isolates the facial region through Haar cascade–based detection, and applies a series of preprocessing steps to enhance …
Published in Journal of Image Processing & Pattern Recognition Progress · Vol. 13, Issue 1, 2026 · pp. 35–45 Read article
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Anticipated Root Coverage Utilizing the Minimally Invasive VISTA Technique with and without Autologous L-PRF: Documentation of Two Case Studies
Abstract: Gingival recession refers to the downward movement of the marginal gingiva from its typical location on the tooth crown to levels along the root surface beyond the cemento-enamel junction. Miller Class I and Class II recession are those for which the prognosis and chances of clinical success is greatest, and numerous evidences in the existing literature reports that the Coronally Advanced Flap (CAF) based procedure along with autologous subepithelial connective …
Published in Research and Reviews: A Journal of Dentistry · Vol. 14, Issue 3, 2023 · pp. 24–30 Read article
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Stem Cells in Dentistry A Review
Abstract: While the regeneration of a lost tissue is known to mankind for several years, it is only in the recent past that research on regenerative medicine/dentistry has gained momentum and eluded the dramatic yet scientific advancements in the field of molecular biology. The growing understanding of biological concepts in the regeneration of oral/dental tissues coupled with experiments on stem cells is likely to result in a paradigm shift in the …
Published in Research and Reviews: A Journal of Dentistry · Vol. 2, Issue 1-3, 2011 · pp. 50–59 Read article
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Effect of Zaroor-e-Aelwa in Non-healing Ulcer: A Case Report
Abstract: Non-healing ulcer is one of the major health issues in and around the globe. It affects the quality of life, decreases work efficiency, causes loss in confidence, restricts mobility, causes anxiety, depression and isolation from society. Non-healing ulcers (Qurooh-e-Aseeerat-ul-Indamaal) are those ulcers which fail to heal by conservative treatment within 6 weeks. Its reported prevalence in India in the year 2004 was 4.8 per 1000 population. About 1% of total …
Published in Research and Reviews : Journal of Surgery · Vol. 9, Issue 1, 2020 · pp. 25–28 Read article
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Factors Affecting Mammalian Embryo Culture: A Detailed Review
Abstract: Human IVF has made remarkable progress, but optimizing the in vitro environment remains essential and crucial for supporting embryo development and improving overall clinical outcomes in assisted reproductive technologies (ART). Even with advances in complex culture media, incubator design, and laboratory workflows, embryos grown outside the body are still exposed to chemical and physical stressors that can significantly affect their developmental potential. In this review, we discuss key chemical stressors, …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 4, Issue 1, 2026 · pp. 1–11 Read article
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Synthesis, Characterization of New Imidazolidin-4-One Containing Azo Compound Derived from Acetylacetone as Antibacterial and Antioxidant Agents
Abstract: In the present study, new derivatives of imidazolidine-4-one was prepared. Which involved reactions to diazonium salt of o-methoxy aniline with acetylacetone in the presence of sodium hydroxide, and isolating the azo compound as a brown precipitate. The azo diketone reacts efficiently with aromatic amine derivatives to produce Schiff bases as a light yellow and dark brown precipitates, and from this Schiff bases three derivatives of imidazolidine-4-one was prepared by reacting …
Published in Journal of Modern Chemistry & Chemical Technology · Vol. 17, Issue 1, 2026 · pp. 94–114 Read article
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Live Epidemiological Tracking of COVID-19 in Senegalese Participants of the Hajj
Abstract: Background: Since the COVID-19 outbreak, global efforts have focused on controlling the disease. However, intense cross border movements pose a risk for the emergence of new SARS-CoV-2 strains. A recent example is the detection of cases among the 2024 Senegalese pilgrims returning from Mecca, Saudi Arabia. Investigations of these cases have revealed genomic evolution of the virus. The lack of surveillance may lead to the emergence of high-threat strains. This …
Published in Recent Trends in Infectious Diseases · Vol. 2, Issue 2, 2025 · pp. 8–16 Read article
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Orthodontics during the COVID-19 Times: Fight or Flight-A Literature Review
Abstract: The corona virus (SARS-CoV-2) a Nano-sized entity has led to a halt in our existence, confining and isolating the mankind. In spite of the regional and national lockdown being prevailed in most of the countries there still is a surge and swell in the number of cases and the graph is being increased continuously. New normality can be covered under three phases, starting with the preparatory phase which covers the …
Published in Research and Reviews: A Journal of Dentistry · Vol. 12, Issue 2, 2021 · pp. 1–9 Read article
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Marine Fungi – An Expandable Source for Production of Novel Bioactive Metabolites: A Comprehensive Review
Abstract: The marine environment, representing the largest and most extreme biome on Earth, serves as an unparalleled reservoir of biodiversity. Within this vast ecosystem, marine fungi have emerged as a prolific source of structurally diverse and pharmacologically active secondary metabolites. Dwelling in habitats characterized by extreme high salinity, high hydrostatic pressure, and low temperatures, these microorganisms have evolved unique biochemical and metabolic pathways to synthesize novel compounds, including pyrrole-imidazole alkaloids, cyclic …
Published in International Journal of Fungi · Vol. 3, Issue 1, 2026 · pp. 30–37 Read article
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A Review on Evolution of Medicine After and During Corona
Abstract: As of the beginning of 2023, 6.7 million people had perished from COVID-19, according to the World Health Organization. However, there have also been some positive developments, such as the notable decline in influenza-related deaths in the first year of the pandemic as a result of masking and social isolation, as well as the quick adoption of vaccines utilizing cutting-edge technologies like mRNA vaccines, which hold out great promise for …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 14, Issue 1, 2024 · pp. 1–9 Read article
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Plant-Derived Antimicrobials as Next-Generation Solutions to Multidrug Resistance
Abstract: The steady rise of multidrug-resistant (MDR) pathogens is reshaping how clinicians, researchers, and policymakers think about infection control. When bacteria acquire the ability to survive exposure to three or more antibiotic classes at once—whether through efflux pumps, enzyme-mediated drug destruction, target modifications, or reduced membrane permeability—treatment options narrow dramatically, hospital stays lengthen, and mortality climbs. Conventional pharmaceutical pipelines have struggled to keep pace with this biological arms race, pushing the …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 17, Issue 2, 2026 · pp. 27–40 Read article
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Frequency and Effect of CCR5 Alleles on HIV-1 Disease Progression among Untreated Seropositive Individuals Visiting Gondar University Teaching Hospital
Abstract: Abstract:The natural history of HIV-1 infection varies considerably from one individual to another, with some individuals progressing to AIDS rapidly after primary infection, while others remain clinically asymptomatic with no evidence of immune dysfunction. Recent studies have shown that reasons for progression and non-progression are multi-factorial and may involve genetic, virological and immunological factors that influence HIV disease progression in various ways. Chemokine receptors act as important co-receptors mediating the …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 5, Issue 1, 2015 · pp. 8–13 Read article
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Dental Pulp Stem Cells Derived from Wisdom Teeth as Multitarget Biological Modulators of Alzheimer’s and Parkinson’s Disease: Mechanistic Insight and Translational Perspective
Abstract: Alzheimer’s disease and Parkinson’s disease are chronic, progressive neurodegenerative disorders with complex pathogenic pathways such as neuroinflammation, oxidative stress, mitochondrial dysfunction, synaptic degeneration, and reduced neurotrophic signalling. Despite the large amount of research, the pharmacological treatments in use offer only symptomatic relief and cannot significantly prevent or slow down disease progression sufficiently; new pathogenetic treatment strategies are necessary. In recent years, stem cell-based approaches have gained interest as potential therapeutic …
Published in Research and Reviews: A Journal of Dentistry · Vol. 17, Issue 2, 2026 · pp. 7–28 Read article
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Harnessing the Bioactive Potential of Calotropis gigantea and Calotropis procera
Abstract: The medicinal plants of the Apocynaceae family Calotropis gigantea and Calotropis procera have gained more and more interest as source of bioactive molecules for biomedical applications like cancer therapy. They have various pharmacological activities, which are believed to be linked to various phytochemical constituents such as cardenolides, cardiac glycosides, flavonoids, triterpenoids, steroids, phenolic compounds, alkaloids, and proteins in their latex. The recent molecular and cellular studies show that extracts and …
Published in International Journal of Molecular Biotechnological Research · Vol. 4, Issue 2, 2026 Read article