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169 articles for “Validation”
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Molecular Docking and Interaction of Anthocyanin Derivatives in Regulating Hippo-taz Pathway for Renal Injuries
Abstract: Introduction: The Hippo pathway plays a pivotal role in renal disease, with Yes-associated protein (YAP) exhibiting promise for combined treatments. The crucial evaluation of YAP-targeted drug safety and efficacy through preclinical studies is imperative. Additionally, α-SMA and SMAD3 emerge as potential therapeutic targets in renal fibrosis, driving ongoing research toward innovative interventions. Materials and Methods: In the systematic identification of therapeutic secondary metabolites, Anthocyanin derivatives were methodically retrieved from the …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 2, Issue 1, 2024 · pp. 23–38 Read article
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Study and Thermal Analysis of a Rectangular Duct with Z-shaped Baffle Using Ansys
Abstract: This project aims to enhance heat transfer in a rectangular duct by utilizing Z-shaped baffles. It involves creating a 3D CAD model using SolidWorks and validating it in ANSYS Fluent 2019 R2. The study focuses on analyzing the effect of baffle arrangement, height, and angle on heat transfer rate. Comparative analysis is conducted between rectangular ducts with a 60° angle and heights of 4 mm, 6 mm, and 8 mm. …
Published in International Journal of Energy and Thermal Applications · Vol. 1, Issue 2, 2023 · pp. 14–30 Read article
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Multi-phase Flow Simulation Using Computational Fluid Dynamics
Abstract: Computational fluid dynamics (CFD)-based multi-phase flow simulation is a fast developing topic with broad applications in many scientific fields and industry. An extensive account of current developments, difficulties, and uses in multi-phase flow simulations is given in this review paper. Important modeling strategies, numerical methods, validation procedures, and new developments in CFD-based multi-phase flow analysis are covered. This paper is to contribute to the ongoing development and use of CFD …
Published in International Journal of Machine Systems and Manufacturing Technology · Vol. 1, Issue 2, 2023 · pp. 28–34 Read article
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Design and Optimization of Radial Turbines for Waste Heat Recovery Applications
Abstract: Waste heat recovery (WHR) offers a compelling way to improve sustainability and energy efficiency in several different industrial sectors. In waste heat recovery (WHR) systems, radial turbines are essential because they capture waste heat and transform it into useful mechanical or electrical energy. A thorough summary of the design and optimization concepts guiding radial turbines for WHR applications is given in this review article. After outlining the basic concepts of …
Published in International Journal of Mechanical Dynamics and Systems Analysis · Vol. 1, Issue 2, 2023 · pp. 52–58 Read article
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Assessing the impact of E-business Technology on Supply Chain Management-in Context of Indian Industries
Abstract: E-business processes and internet technologies offer powerful competitive tools for higher revenues and profits in the industry. Creating an efficient supply chain network is crucial for providing affordable products with high quality, which is essential for gaining a competitive edge. Implementing e-business processes in the supply chain aims to improve overall performance by leveraging information technology advancements for easier coordination and reduced information costs. The research focuses on assessing the …
Published in International Journal of Manufacturing and Production Engineering · Vol. 2, Issue 1, 2024 · pp. 9–16 Read article
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Gene prioritization of colorectal cancer using computational approach
Abstract: Colorectal cancer (CRC) continues to be a major worldwide health issue, underscoring the need to pinpoint crucial genetic elements influencing its initiation and advancement. In this investigation, we utilize sophisticated computational methods to prioritize potential genes linked to CRC development. Through the utilization of various bioinformatics tools and comprehensive methodologies, we systematically examine extensive microarray datasets to identify potential genetic contributors. Initially, a vast amount of CRC microarray data (approximately …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 2, Issue 1, 2024 · pp. 39–52 Read article
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A Pre-experimental Evaluation of a Structured Educational Program on Awareness of Mosquito-borne Diseases in Senior Secondary School Students in Punjab
Abstract: Introduction: Mosquitoes constitute the most important single family of insects from the standpoint of human health. They are found all over the world. The four important groups of mosquitoes in India that are related to disease transmission are the Anopheles, Culex, Aedes, and Mansonia. Aims: The aims of the study are to assess the effectiveness of structured teaching program on knowledge regarding mosquito-borne diseases among students of senior secondary schools …
Published in International Journal of Evidence Based Nursing And Practices · Vol. 2, Issue 1, 2024 · pp. 7–14 Read article
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Time Series Sales Forecasting Using ARIMA Model
Abstract: Sales forecasting is a critical application in various industries and presents one of the most challenging problems worldwide. One method of prediction involves identifying patterns in historical data, where the outcome is known in advance and can be validated using more recent data. If a pattern consistently leads to the same outcome, it can be considered a genuine relationship. This method is highly flexible and can be utilized with diverse …
Published in International Journal of Algorithms Design and Analysis Review · Vol. 2, Issue 1, 2024 · pp. 17–27 Read article
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The Electromagnetic Transients in Compensated High Voltage Power Lines
Abstract: This paper addresses the simulation of the transients developed in high voltage lines, which are initiated by lightning discharges. The analysis allows for compensated and uncompensated lines. Both the individual and simultaneous series inductive and shunt capacitive compensation types can be dealt with. The sizes and locations of the compensating elements are included in the analysis. Numerous studies on the transient concentrated stresses across these elements and the related protection …
Published in International Journal of Electrical Power and Machine Systems · Vol. 1, Issue 2, 2023 · pp. 1–8 Read article
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Optimizing Power Generation from Building Ventilation Systems: A Study on Exhaust Fan Efficiency
Abstract: Due to population growth, the world's energy consumption has increased dramatically in both wealthy and developing nations in recent years, and by 2042, it is predicted to have doubled or more. Since a few years ago, the use of innovative sustainable power sources to meet energy demands has been gradually increasing. We've chipped away at a different idea because of this. As an alternative energy source, renewable energy (RE) resources …
Published in International Journal of Electrical Power and Machine Systems · Vol. 1, Issue 2, 2023 · pp. 22–27 Read article
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Quantitative Research on Gen Z Slang Terms for a Diverse Group of People
Abstract: This study objective is to determine the various individuals who employed vocabulary connected with Generation Z and to discover who those persons were. Through the use of Google forms, twenty Gen Z slang terms associated were posed to the various participants for testing. The data are collected from the participants by the researcher through the use of Google Forms, and the researcher is the one who is responsible for developing …
Published in Emerging Trends in Languages · Vol. 1, Issue 1, 2024 · pp. 24–31 Read article
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Minimisation of Fire Outbreaks in Nigeria via Fire Safety Education in Architecture in the Universities
Abstract: Frequent fire outbreak in buildings is a problem in Nigeria which has led to the loss of many human lives and the destruction of substantial properties. To minimize this menace in Nigeria, it therefore became extremely important to carry a research work to recap the architecture curriculum of study with respect to fire safety education in the universities in Nigeria, to provide guidelines for its improvement. Desktop study was considered …
Published in International Journal of Environmental Planning and Development Architecture · Vol. 2, Issue 1, 2024 · pp. 53–63 Read article
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Electromagnetic Transients in Compensated Power Lines- Revisited: New Approach and Case Studies
Abstract: This paper addresses the simulation of the electromagnetic transients developed in high voltage power lines, which are initiated by lightning discharges. The analysis can handle both individual and simultaneous series inductive and shunt capacitive compensation types. The sizes and locations of the compensating elements are included in the analysis. The derived Laplace s-domain mathematical model applies the concept of the ABCD transmission constants representing equivalent two-port networks. The resulting currents …
Published in International Journal of Electrical and Communication Engineering Technology · Vol. 2, Issue 1, 2024 · pp. 19–26 Read article
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Spirituality-Based Psychotherapies in Relation to Social Media Addiction: A Review
Abstract: Social media addiction has become a pressing concern, characterized by compulsive usage that significantly impacts mental health. In the digital age, where the boundaries between the virtual and the real have blurred, social networking sites (SNS) have emerged as pivotal platforms that shape the lives of young people. Most people's life now revolve around social networking sites, particularly those of teens. Excessive engagement with social media can have adverse effects …
Published in International Journal of Behavioral Sciences · Vol. 1, Issue 2, 2024 · pp. 39–47 Read article
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Investigating the Relationship Between Environmental Concern and Waste Management in Tourism
Abstract: Tourism can bring both positive and negative effects in terms of the environment, which is the prevention of negative effects, including the necessity to preserve the environmental and even cultural, social resources of touristic areas. The purpose of this research is to investigate the relationship between environmental concerns and waste management in Damavand mountain tourism areas in 2017. This study was carried out as a survey and is of the …
Published in International Journal of Climate Conditions · Vol. 1, Issue 2, 2024 · pp. 47–53 Read article
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Automatic Laser Welding Machine Using PLCs
Abstract: This paper presents the design and implementation of an automatic laser welding machine controlled by a Programmable Logic Controller (PLC) technology. Laser welding has gained significant attention in various industries due to its precision, speed, and efficiency. However, manual operation of laser welding systems can be labor-intensive and prone to errors. The proposed system aims to address these challenges by automating the welding process using PLC-based control. The system architecture …
Published in International Journal of VLSI Circuit Design & Technology · Vol. 2, Issue 1, 2024 · pp. 9–15 Read article
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Comparative Analysis of Bioactive Phytochemical Profiles of Moringa Oleifera and Aegle Marmelos Grown in Bundelkhand
Abstract: A comparative analysis of the bioactive phytochemical profiles of Moringa oleifera and Aegle marmelos grown in the Bundelkhand region was conducted to explore their potential health benefits. These properties make healing plants valuable in herbal medicine, supporting various aspects of health and well-being. The study aimed to determine the differences in the concentrations of bioactive compounds such as phenolic, flavonoids, alkaloids, and vitamins C and E in the leaves and …
Published in Emerging Trends in Metabolites · Vol. 1, Issue 2, 2024 · pp. 14–24 Read article
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Molecular Docking of Nigella Sativa Phytocompound as Inhibitors of Transcription Factors NF-KB Implicated in Rheumatoid Arthritis
Abstract: Objectives: Nigella sativa, a plant considered around the world as the most treasured nutrient-rich herb for centuries together in different civilizations, is exceptionally known for its high levels of antioxidant properties. Free radical intensification due to oxidative stress plays a key role in the pathogenesis of rheumatoid arthritis by activating the NF-KB protein that regulates the expression of the genes involved in inflammation. Methods: This study involves in-silico approach to …
Published in International Journal of Molecular Biotechnological Research · Vol. 2, Issue 2, 2024 · pp. 42–55 Read article
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Exploring the Therapeutic Potential of Grapeseed Phytoconstituent Through Molecular Docking Analysis for Multiple System Atrophy Treatment
Abstract: Objective: Alpha-synuclein (α-Syn) aggregates are a common neurodegenerative disorder associated with Parkinson’s disease and multiple system atrophy (MSA). As a fruit that is extensively grown, grapes have several pharmacological advantages when it comes to reducing oxidative stress. Research has indicated that grape seed phytoconstituents have a major effect on α-Syn. The objective of this study is to inquire into the pharmacological characteristics and potential therapeutic applications of grape seed derivatives …
Published in International Journal of Molecular Biotechnological Research · Vol. 2, Issue 2, 2024 · pp. 14–26 Read article
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Time and Frequency Response of Non-uniform Overhead Lines Under Corona
Abstract: This study presents an efficient and direct technique for determining both the time and frequency responses of non-uniform overhead power transmission lines operating under corona conditions. The assumed-line's non-uniformity is due to the conductors’ sag. Expressions will be presented for the location-dependent line surge impedance and the unevenly distributed lines’ electrical parameters. The analysis starts with solving the relevant system of differential and algebraic equations, subject to the boundary conditions. …
Published in International Journal of Electrical Machine Analysis and Design · Vol. 2, Issue 2, 2024 · pp. 25–33 Read article