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465 articles for “Toxic effects”
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A New Extractive Spectrophotometric Method for the Determination of Oxydemeton methyl in Relation to its Environmental and Toxicological Analysis
Abstract: In view of the wide agricultural use of oxydemeton methyl insecticide and its associated toxic effects, it has been determined in the soil, water and foodstuffs to assess its environmental relevance. A new, simple and sensitive extractive spectrophotometric method has been developed for the purpose. It is based on microwave-assisted alkaline hydrolysis of insecticide to form 2-ethylsulfinyl-ethyl mercaptan and transformation of the latter through reaction with carbon disulphide and nickel(II) …
Published in Research and Reviews: A Journal of Toxicology · Vol. 2, Issue 2, 2012 · pp. 1–11 Read article
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In Vivo and In Vitro Antioxidative Efficacy of Naringenin on Cadmium -Induced Toxicity in Rats
Abstract: The aim of the study was to investigate the in vivo circulating antioxidants level such as vitamin C, vitamin E and GSH in Cadmium (Cd) induced toxic rats and the protective efficacy of naringenin via in vitro free radical scavenging assays. In this investigation cadmium chloride (5 mg/kg body weight (b.w) was administered orally (p.o) for 28 days to induce toxicity. Naringenin was pre-administered orally (50 mg/kg body weight) for …
Published in Research and Reviews: A Journal of Toxicology · Vol. 3, Issue 3, 2013 · pp. 9–16 Read article
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Development of Antioxidant Based Therapeutics in Unani System of Medicine
Abstract: During the last decades, several studies have examined the potential role of oxidative stress in the development of various diseases like cancer, Parkinson's disease, Alzheimer's disease, atherosclerosis, myocardial infarction, chronic fatigue syndrome etc. Oxidative stress can cause toxic effects through the production of peroxides and free radicals that damage all components of the cell, including proteins, lipids, and DNA. Unani system of medicine has a wealth of antioxidants that can …
Published in Research & Reviews : A Journal of Unani, Siddha and Homeopathy · Vol. 5, Issue 3, 2018 · pp. 1–4 Read article
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Antibacterial Property of Crocus Sativus L.
Abstract: ABSTRACTCrocus sativus commonly called saffron has been used widely in Middle East and South East Asia as a drug to promote health and to fight diseases. Saffron though cultivated in different parts of the world, is mainly cultivated in Iran. It has wide range of medical uses such as antitumor, antifungal and antiinflammatory activities. Characteristic components of saffron are crocetin, picrocrocin and safranal that are responsible for color, bitter taste, …
Published in Research & Reviews : Journal of Herbal Science · Vol. 1, Issue 1, 2012 · pp. 17–23 Read article
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Current Insight to the Uses of Rauwolfia: A Review
Abstract: Rauwolfia serpentina is an Indian medicinal plant and is a safe and effective treatment for poisonous reptiles. The plant was used by many physicians throughout India in the 1940s and then was used throughout the world in the 1950, including in the United States and Canada. It fell out of popularity when adverse side effects, including depression and cancer, become associated with it. In this review we focus on the …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 3, Issue 3, 2016 · pp. 1–4 Read article
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Study on safety of Unani pharmacopeial formulation Qurs Kusta Khabas- al- Hadeed and Habb- e-Marwareed in cases of Sailanur Reham (Leucorrhoea)
Abstract: Leucorrhoea is nothing but excessive vaginal discharge, it is common gynaecological complaint . Main objective of the present study was to study safety parameter of Unani formulation Qurs-e- Kusta Khubs al Hadeed and Habb-e-Marwarweed in cases of Sayalan-al-Rahim (Leucorrhoea).Study was jointly conducted in the laboratory at Regional Research Institute of Unani Medicine, New Delhi. For this 56 females patientsin the age group of 18-60 years presenting sign and symptom with …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 8, Issue 1, 2023 · pp. 1–7 Read article
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A Study and Report on Due (Drug Utilization Evaluation) of Cardiovascular and Endocrine Disorders/Diseases in Inpatient Units of Hospitals
Abstract: In recent years drug utilization studies have become a potential tool to be used in the evaluation of health systems. On the process of drug utilization studies focus on factors related to prescribing, dispensing, administering, and taking of medication, and its associated events. Drug utilization data are available from databases- computerized or otherwise. From these databases different types of information, qualitative or quantitative or referring to a particular population are …
Published in Trends in Drug Delivery · Vol. 8, Issue 3, 2023 · pp. 11–32 Read article
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Ascorbic Acid Indicates Positive Role in Detoxification Studied on the Fresh Water Fish, Channa Orientalis (Schneider)
Abstract: Aquatic animals provide useful data for toxicological evaluations. Ascorbic acid acts as a detoxifier reduces which toxicity of pesticides. In this present work Ascorbic acid indicates positive role in detoxification. The study was carried out on the fresh water fish, Channa orientalis (Schneider) These aquatic organisms are adaptive and convenient for laboratory experimentation for toxicity testing. The role of ascorbic acid on experimental fish, Channa orientalis is discussed in this …
Published in Research and Reviews: A Journal of Toxicology · Vol. 11, Issue 2, 2024 · pp. 6–9 Read article
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Toxic Epidermal Necrolysis Induced by Diclofenac Sodium in a Dental Patient: A Case Report
Abstract: Diclofenac sodium is a widely prescribed non-steroidal anti-inflammatory drug in dental practice. Propionic acid derivatives and oxicams have been reported to be associated with erythema multiforme and Steven-Johnson syndrome. Here the authors present a rare case report of toxic epidermal necrolysis (TEN) induced by diclofenac sodium. The patient presented in dental clinic with toothache for which planned tooth extraction was done under antibiotic cover. Post extraction, patient was prescribed diclofenac …
Published in Research and Reviews: A Journal of Dentistry · Vol. 4, Issue 1, 2013 · pp. 27–29 Read article
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Assess the Level of Knowledge in Clinical Toxicology Among the Delegates Attended the State Level Conference in Clinical Toxicology
Abstract: This abstract highlights the essential role of healthcare professionals, including doctors, nurses, and physician assistants, in continually learning and enhancing their skills in clinical toxicology. Clinical toxicology is a crucial field for managing patients who have been poisoned or are experiencing drug overdoses. In a hospital setting, the professionals, such as those working in the poison control center, play a vital role as first responders in cases of toxicological emergencies. …
Published in Journal of Nursing Science & Practice · Vol. 13, Issue 3, 2023 · pp. 14–18 Read article
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Modulation of Receptor Proteins: A Recent Paradigm in Drug Discovery and Target
Abstract: The main aim in drug discovery is to design different ligands those work on specific drug targets. However, various effective drugs work through the modulation of many proteins than single target. Advancement in system biology are establishing a phenotypic strength and a network structure, which suggests that, the excellent selective compounds may be performed less than desired clinical efficacy in comparison to multi-target drugs. In this new appreciation of the …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 5, Issue 1, 2018 · pp. 14–24 Read article
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Nephrotoxic Effect of Herbal Medicine and Supplements: A Review
Abstract: Nowadays, alternative medicines have become a multibillion-dollar industry and continue growing. Herbal medicine is one of the primeval forms of medicine which is prepared exclusively from herbal plants. The Ayurvedic medicinal cure method is also been used as a prescription for chronic diseases such as cancer, asthma, diabetes, and end-stage renal diseases and increasing interest in European countries respectively. According to the report of world health organization (WHO), 4 billion …
Published in Research and Reviews: A Journal of Toxicology · Vol. 9, Issue 2, 2019 · pp. 28–35 Read article
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Paraphenylenediamine Poisoning: A Review of Literature
Abstract: Any substance dangerous to living organisms when either applied internally or externally, destroy the action of vital functions or prevent the continuance of life is known as poison. Cosmetics, medicines, and other household items could lead to a serious poisoning if accidently consumed by children. The home environment is the primary location of most poisonings, with over 90% of reported poisonings occurring at home. Most non-fatal poisonings occur in children …
Published in Research and Reviews: A Journal of Toxicology · Vol. 3, Issue 3, 2013 · pp. 17–24 Read article
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Photochemical Detoxification of Arsenic- and Mercury-Contaminated Soils: Geochemical Mechanisms and Pathways
Abstract: This study evaluates the geochemical aspects of soil detoxification in areas contaminated with arsenic (As) and mercury (Hg), emphasizing sustainable strategies for improving soil health and ensuring safe crop production. The research provides an ecological and toxicological assessment of regional soils and classifies them base on the concentration and mobility of toxic elements. Although the current levels of As and Hg do not yet present a critical risk to agricultural …
Published in International Journal of Photochemistry and Photochemical Research · Vol. 4, Issue 1, 2026 · pp. 06–10 Read article
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Nutraceuticals as Adjunctive Treatment in Cancer Exploring Efficacy and Mechanism of Action
Abstract: Dietary habits are a critical factor in cancer prevention, with plant-based diets rich in vegetables and fruits associated with reduced cancer risk. Nutraceuticals—bioactive compounds derived from food and supplements—have gained attention for their potential in cancer prevention and therapy. Phytochemicals such as flavonoids, polyphenols, and alkaloids exhibit anti-cancer properties through mechanisms including antioxidant activity, anti-inflammatory effects, inhibition of tumor growth, and induction of apoptosis. Key nutraceuticals include alkaloids (e.g., caffeine, …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 12, Issue 1, 2025 · pp. 35–45 Read article
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Acute Toxicity and Behavioral Alterations of Oligochaete Worm, Branchiura sowerbyi Exposed to Diazinon
Abstract: In the present study, acute toxicity of the organophosphate pesticide, diazinon, was evaluated under experimental condition to Oligochaete worm, Branchiura sowerbyi. The 96 h LC50 with 95% confidence limits of B. sowerbyi was 2.87 (2.50–3.17) mg/l. None of the unexposed control worm died during the experiment. Mortality rate between each dose and mortality rate between 24–96 h depending on time was correlated. The mortality rate also varied significantly (p<0.05) with …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 8, Issue 2, 2018 · pp. 1–5 Read article
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Drug-Resistant TB—Problem and Management: a Review
Abstract: Tuberculosis (TB) is one of the oldest diseases known to affect humans. TB is a major cause of death worldwide. The bacteria Mycobacterium tuberculosis is the causative agent of TB. It usually affects the lungs and causes pulmonary TB. The intestine, meninges, bones, joints, lymph glands, skin and other tissues of the body are also affected. TB caused by drug-susceptible strains is curable in virtually all the cases after proper …
Published in Research & Reviews : A Journal of Unani, Siddha and Homeopathy · Vol. 6, Issue 3, 2019 · pp. 30–34 Read article
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An in-silico toxicity study of the phytocompounds found in Pongamia pinnata leaves using the ProTox-II web server
Abstract: The aim of the current study was to determine the Insilco toxicity of the phytocompound present in the leaves of Pongamia pinnata. The leaves of Pongamia pinnata have long been used in traditional medicine for their therapeutic properties. Nowadays, herbal toxicity is a common problem caused by incorrect dosage. The FDA reviews the safety and effectiveness of herbal products only in response to patient or health care provider complaints—problems with …
Published in Research and Reviews : Journal of Crop science and Technology · Vol. 13, Issue 1, 2024 Read article
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In Silico Docking Analysis to Identify Therapeutic Benzoic Acid Derivatives for Acute Myeloid Leukaemia
Abstract: Background: The study is anchored to initiate subjugation against modern cancer therapy for Acute Myeloid Leukaemia (AML) which involves natural therapeutics as an alternative therapy that would degrade the prospect of adverse side effects along with anti-cancer properties. Objectives: Collate the various characteristics of Giltertinib with natural benzoic acid derivative phytochemicals for a disquisition regarding their similarities and differences in the context of providing adverse side effects. Methods: ADME toxicity …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 1, Issue 2, 2023 · pp. 50–63 Read article
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Review on Histological Effect of Lead on Liver and Kidney
Abstract: Our environment can be polluted by environmental toxins which are chemicals and other materials produced largely from industry and its products. There are large numbers of environmental toxicants which are potentially harmful to health. These large numbers of environmental toxicants can be divided into three major categories (heavy metals, air pollutants, and pesticides) and they are commonly studied environmental toxicants. Environmental toxins can be entered into the body by various …
Published in Research and Reviews: A Journal of Toxicology · Vol. 10, Issue 1, 2020 · pp. 8–29 Read article