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193 articles for “Three-dimensional”
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Controlled Release Drug Delivery Using 3D Printing Techniques: A Current Scenario In Personalized Medicine
Abstract: Three-dimensional (3D) printing is particularly influencing the pharmaceutical manufacturing sector in the creation of controlled release drug delivery systems. This technology enables the precise fabrication of personalized medicines with tailored drug release profiles, dosages, and geometries, marking a significant advancement over traditional mass production methods. An array of 3D printing techniques, including extrusion-based, powder-based, and others, can be used to build complex dosage forms that regulate drug release through processes …
Published in Trends in Drug Delivery · Vol. 12, Issue 3, 2025 · pp. 28–43 Read article
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A Review on Nanosponges Drug Delivery System
Abstract: The main issue that the researchers are dealing with is targeted medication delivery to locations. Crosslinking polymers produce nanosponges, which are three-dimensional drug delivery systems at the nanoscale. They have the benefit of having a large capacity to carry different-sized medications. There are numerous sizes and shapes for nanosponges. Compared to alternative delivery methods, nanosponges are preferable because they may offer a regulated medication release pattern with targeted Medication administration. …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 12, Issue 2, 2025 · pp. 68–76 Read article
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Polymer–Gel Composite Phase Change Materials: A Functional Polymer Composite Approach for Solar-Thermal Energy Storage in Building Facades
Abstract: This study investigates polymer–composite phase change materials (PCMs) in the form of polymer–gel hybrids as multifunctional systems for solar–thermal energy storage in building façades. Paraffin- and PEG-based PCMs were embedded into polyurethane and acrylic gel matrices to create shape-stabilized polymer–composites with high PCM loading (70–80 wt%). Differential Scanning Calorimetry (DSC) confirmed distinct melting/freezing transitions at ~56°C (paraffin) and ~42°C (PEG), with enthalpy values of 120–150 J/g, closely matching theoretical predictions, …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 36–51 Read article
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Gear-Related Stress Analysis and Comparison Between the Fem and Agma Standards
Abstract: In many different devices, gears enable the efficient transfer of motion and torque. They are an essential component of modern mechanical power transmission systems. It has been demonstrated that bending and surface contact stresses at the gear tooth are the primary causes of gear failure, despite their widespread use. Too much stress can lead to tooth wear, pitting, or breakage, which can ultimately reduce the operating life and reliability of …
Published in Trends in Mechanical Engineering & Technology · Vol. 15, Issue 3, 2025 · pp. 13–18 Read article
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Design and Analysis of G+4 Building with Ductile Detailing
Abstract: This study presents the structural design and analysis of a G+4 residential building, with a specific focus on ductile detailing to enhance seismic performance. Ductility plays a crucial role in enabling structures to absorb and dissipate energy during seismic events, thereby minimizing structural damage and improving safety. The project emphasizes key reinforcement strategies such as beam-column junction detailing and confining reinforcement, which are critical to preventing brittle failures and improving …
Published in Journal of Structural Engineering and Management · Vol. 12, Issue 2, 2025 · pp. 1–9 Read article
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Impact on Mobility and Mortality in Minimally Invasive Surgeries
Abstract: Minimally invasive surgery (MIS) presents numerous advantages such as fewer complications, shorter hospital admissions, and reduced patient discomfort. This surgical method has progressed significantly, with laparoscopy being one of its earliest applications. Laparoscopy involves the insertion of miniature cameras and instruments through small incisions. Robotic-assisted surgery, another form of MIS, enhances surgical precision and offers a three-dimensional view. With technological developments, MIS has gained widespread acceptance among both surgeons and …
Published in Research and Reviews : Journal of Surgery · Vol. 14, Issue 3, 2025 · pp. 8–21 Read article
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Aerodynamic Effects of Wind on Multi-Story Structures: A Height- and Terrain-Based Analysis
Abstract: Wind loads are a critical consideration in the structural design of buildings, with direct implications for safety and serviceability. This study investigates the aerodynamic behavior of reinforced cement concrete (RCC) buildings under varying heights and terrain conditions, in accordance with IS: 875 (Part 3): 2015. 12 structural models representing 20 m, 35 m, and 50 m tall buildings were analyzed using extended three-dimensional analysis of building system (ETABS) across four …
Published in Journal of Offshore Structure and Technology · Vol. 12, Issue 3, 2025 · pp. 1–14 Read article
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STRUCTURAL–EPIGENOMIC ATLAS: CNV/SV- DRIVEN PROGNOSTIC REFINEMENT ACROSS CANCERS
Abstract: Structural genomic alterations, including copy number variations (CNVs) and structural variants (SVs), play a central role in cancer initiation and progression. These alterations extend beyond gene dosage effects and interact dynamically with epigenomic mechanisms such as DNA methylation, histone modifications, and three-dimensional chromatin organization. Recent pan-cancer studies have demonstrated that CNV burden and SV signatures reflect key oncogenic processes including chromothripsis, homologous recombination deficiency, enhancer hijacking, and extrachromosomal DNA (ecDNA) …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 4, Issue 1, 2026 · pp. 35–43 Read article
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AI-Driven Topology Optimization of Woven Fiber-Reinforced Composite Chassis Structures for Electric Vehicles Under Crash Loading
Abstract: The structural design of an electric vehicle (EV) chassis represents a unique engineering challenge to achieve minimal weight while meeting occupants' safety requirements during high-energy crash conditions without compromise to the battery housing's integrity or the geometrical constraints of the electric powertrain package. In this paper, a single framework is proposed to integrate physics-based artificial intelligence (AI) surrogate models using PINNs, CNN-accelerated topology optimization, and FEA to design woven fiber-reinforced …
Published in Journal of Polymer & Composites · Vol. 14, Issue 2, 2026 · pp. 72–89 Read article
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In Silico Identification of Therapeutic Agents for Dengue Virus by Molecular Docking
Abstract: The dengue virus causes serious health issues and a loss of quality of life. Dengue poses a yearly threat to half of the world’s population. The drugs that are based on allopathy are expensive and also exhibit toxic effects on tissues and biological activities. It is also generally accepted that most pharmacologically active drugs, including those derived from medicinal plants, are isolated from natural sources. The present study is directed …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 13, Issue 2, 2026 · pp. 01–14 Read article
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Corrugated Tube Shell-and-Tube Heat Exchanger Using Epoxy-Based Polymer Composite Coatings for Lightweight and Efficient Thermal Systems
Abstract: Corrugated tube geometries are widely recognized for their ability to enhance heat transfer through boundary layer disruption and secondary flow generation. In this study, a combined experimental and computational investigation is carried out to evaluate the thermo-hydraulic performance of a shell-and-tube heat exchanger incorporating corrugated stainless steel tubes integrated with an epoxy-based polymer composite coating and housed within a mild steel shell. Unlike conventional metallic systems, the present work introduces …
Published in Journal of Polymer & Composites · Vol. 14, Issue 2, 2026 · pp. 603–617 Read article
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Influence of Epoxy-Based Thermally Conductive Polymer Composites on the Thermo-Hydraulic Performance of Finned Helical Coil Heat Exchangers Across Flow Regimes
Abstract: The use of polymer composites in heat exchanger applications has gained increasing attention due to their advantages in weight reduction, corrosion resistance, and design flexibility. However, their relatively low thermal conductivity compared to conventional metallic materials remains a key limitation for efficient heat transfer. In this study, the thermo-hydraulic performance of a finned helical coil heat exchanger is investigated with particular focus on epoxy-based polymer composites reinforced with thermally conductive …
Published in Journal of Polymer & Composites · Vol. 14, Issue 2, 2026 · pp. 586–602 Read article
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Enhancement of Flexural Strength in FDM-Printed Components through Taguchi-Based Process Parameter Optimization
Abstract: Additive manufacturing (AM), especially Fused Deposition Modeling (FDM), has emerged as a widely adopted and versatile method for producing three-dimensional components. The process involves the deposition of a thermoplastic filament in a semi-molten state, which solidifies in successive layers to form the final structure. While this method enables the production of complex geometries at relatively low cost, the printed parts often exhibit inferior surface quality and reduced mechanical performance compared …
Published in Journal of Polymer & Composites · Vol. 14, Issue 2, 2026 · pp. 272–280 Read article
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Thermo-Hydraulic Enhancement of Annular Finned Shell-and-Tube Heat Exchangers Using Epoxy-Based Polymer Composites: A Material–Geometry Coupled CFD Investigation
Abstract: Shell-and-tube heat exchangers remain a backbone of industrial thermal systems, yet their performance is often limited by relatively low shell-side heat transfer and the weight and cost associated with conventional metallic components. In this context, the integration of polymer composite materials offers a promising pathway toward lightweight, corrosion-resistant, and performance-tunable heat exchanger designs. The present study investigates the thermo-hydraulic performance of a straight-tube shell-and-tube heat exchanger equipped with annular fins, …
Published in Journal of Polymer & Composites · Vol. 14, Issue 2, 2026 · pp. 669–684 Read article
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Experimental and CFD Investigation of an Epoxy-Based Thermally Conductive Polymer Composite U-Tube Shell-and-Tube Heat Exchanger: A Lightweight Alternative to Conventional Metal Systems
Abstract: Shell-and-tube heat exchangers continue to play a critical role in industrial thermal systems; however, their conventional design based on fully metallic materials often leads to challenges related to weight, corrosion, and cost. In recent years, thermally conductive polymer composites have emerged as promising alternatives, offering improved corrosion resistance and design flexibility. In this study, the thermo-hydraulic performance of a U-tube shell-and-tube heat exchanger is investigated by partially replacing conventional metallic …
Published in Journal of Polymer & Composites · Vol. 14, Issue 2, 2026 · pp. 685–700 Read article
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IoT-Enabled Polymer–Gel PCM Composites for Intelligent Thermal Management in Solar Facade Applications
Abstract: The present study investigates the development of a multifunctional polymer–gel phase change composite designed for solar façade applications with integrated real-time thermal monitoring capability. A crosslinked polyvinyl alcohol–borax matrix was employed as a three-dimensional polymer scaffold to encapsulate paraffin-based phase change material, ensuring leakage-free operation and structural integrity under repeated thermal cycling. Graphite nanoplatelets were incorporated as thermally conductive nano-fillers to enhance heat transfer through the polymer composite via percolation-driven …
Published in Journal of Polymer & Composites · Vol. 14, Issue 3, 2026 · pp. 99–111 Read article
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Dynamic Response Analysis of Isotropic and Orthotropic Rectangular Plates under Clamped-Free Conditions
Abstract: This study explores Theoretical and numerical tools of determining the free vibration properties of isotropic and fiber-reinforced composite rectangular plates. The effect of anisotropy of materials on the dynamic response of the plates is compared between the Aluminium plates and the glass-epoxy laminates. The model used in the study is a three-dimensional finite element model that is designed using a combination of SolidWorks and ANSYS workflow. Clamped-free boundary conditions are …
Published in Journal of Polymer & Composites · Vol. 14, Issue 3, 2026 · pp. 258–274 Read article
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Dual Nozzle 3D Printing of Basalt Fiber–Reinforced Polymer Composites
Abstract: Additive manufacturing or 3Dprinting involves building a three-dimensional object by layering materials based on a computer-created design. Generally, 3D printing using single nozzle process where as strength, quality, wastage, and post reinforcement are drawback of this system. To eliminate and to enhance strength, precise control of fiber reinforcement, good bonding, no need of secondary reinforcement the dual nozzle 3D printing is an emerging additive manufacturing technique. In this process the …
Published in Journal of Polymer & Composites · Vol. 14, Issue 3, 2026 · pp. 620–630 Read article
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Impact of Fracture in Geometrical, Material, and Load Rate Characteristics on J-Integral
Abstract: The present study investigates the influence of load rate, geometrical parameters, and material properties on the J-integral behavior of AA2050-T84 aluminum-lithium alloy using three-dimensional elastic–plastic fracture mechanics (EPFM) analysis. Finite element simulations were carried out using the ABAQUS software to evaluate crack driving forces in compact tension (C(T)) specimens under various mechanical and thermal conditions. The study focuses on the combined effects of strain rate, temperature-dependent strain hardening, specimen thickness …
Published in International Journal of Fracture Mechanics and Damage Science · Vol. 4, Issue 1, 2026 · pp. 38–45 Read article
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Thermo-Fluid Characterization of Corrugated U-Tube Shell-and-Tube Heat Exchanger with Polymer Composite Tube Wall: A Combined CFD and Experimental Investigation
Abstract: Shell-and-tube heat exchangers built with metallic tubes work well thermally, but corrosion problems, extra weight, and the inability to adjust the wall’s thermal properties through material choice remain genuine engineering headaches, particularly for corrosive or weight-critical applications. Over the past few years there has been a fair amount of interest in replacing metal tubes with polymer composite alternatives, since blending thermally conductive fillers — graphite nanoplatelets, boron nitride platelets and …
Published in Journal of Polymer & Composites · Vol. 14, Issue 3, 2026 Read article