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90 articles for “CAN FD”
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In-Silico Repurposing of Antipsychotic Drugs Against Novel Protein Targets in Multidrug-Resistant Mycobacterium tuberculosis
Abstract: Multidrug-resistant TB is a growing worldwide health concern, particularly in high-burden areas. Resistance to frontline drugs like isoniazid and rifampicin is caused by mutations in key Mycobacterium tuberculosis proteins. Given the difficulty of developing new antibiotics, medication repurposing offers a good alternative. The potential use of molecular docking to target resistance-associated TB proteins with FDA-approved antipsychotic drugs is investigated in this work. Three proteins were selected: InhA (PDB ID: 5W07), …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 13, Issue 1, 2026 · pp. 49–63 Read article
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AI-Enabled Optimization of Additively Manufactured Composite Materials for Enhanced Mechanical and Thermal Performance
Abstract: This paper discusses the optimization of multi-objective optimization of enhanced coupling of heat and mechanical properties of 3D printed polymer composite materials by artificial intelligence (AI), as a component of a multi-objective optimization framework. It aims at development of nonlinear printing parameters and material properties relationships to achieve maximum tensile strength and thermal conductivity in polymer composites produced through fused deposition modeling (FDM). Short carbon fiber reinforcement was used to …
Published in Journal of Polymer & Composites · Vol. 14, Issue 2, 2026 · pp. 867–891 Read article
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Revolutionizing Form and Function: Exploring 4D Printing as a Novel Manufacturing Approach for Complex Generative Structures and Customized Formworks
Abstract: This research delves into the transformative potential of 4D printing manufacturing technology, focusing on its innovative application in fabricating intricate generative and computational structures for adaptable formwork in both individualized and mass-customized scenarios. Spanning the interdisciplinary realms of digital design, digital fabrication, and material science, the study comprehensively explores the integration of these diverse fields. Utilizing generative algorithms and parametric design tools, the research employs simulations to realize complex patterns …
Published in International Journal of Manufacturing and Production Engineering · Vol. 1, Issue 2, 2023 · pp. 41–50 Read article
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Pharmacological Review On Enzalutamide
Abstract: A key therapeutic option in the treatment of prostate cancer, especially metastatic castration-resistant prostate cancer (mCRPC), is Enzalutamide, a second-generation anti androgen drug. Enzalutamide, discovered by Charles Sawyer and Michael Jung at the University of California, Los Angeles, was developed and Food and Drug Administration (FDA)-approved in 2012. Its therapeutic significance was further solidified with subsequent extensions in indications to encompass metastatic castration-sensitive prostate cancer and non-metastatic castration-resistant prostate cancer. …
Published in Trends in Drug Delivery · Vol. 11, Issue 2, 2024 · pp. 7–15 Read article
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An in-silico toxicity study of the phytocompounds found in Pongamia pinnata leaves using the ProTox-II web server
Abstract: The aim of the current study was to determine the Insilco toxicity of the phytocompound present in the leaves of Pongamia pinnata. The leaves of Pongamia pinnata have long been used in traditional medicine for their therapeutic properties. Nowadays, herbal toxicity is a common problem caused by incorrect dosage. The FDA reviews the safety and effectiveness of herbal products only in response to patient or health care provider complaints—problems with …
Published in Research and Reviews : Journal of Crop science and Technology · Vol. 13, Issue 1, 2024 Read article
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Comprehensive Approaches to Understanding and Managing Alzheimer’s Disease
Abstract: Alzheimer’s disease is an advanced neurodegenerative disorder described by intense memory loss. It strictly affects the patient’s quality life. The popularity of AD has been increasing in recent years. It is the most common form of mental disorder affecting more than 20 million people in the world. The Alzheimer’s disease is treated with cholinesterase inhibitors or NMDA-receptor (N-methyl D-aspartate) antagonists but here the question is about the therapeutic effect of …
Published in International Journal of Tropical Medicines · Vol. 2, Issue 1, 2025 · pp. 1–9 Read article
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Advanced Design and Prototyping with Fabrication, Architecture, And Material Design Techniques For 3D Printing Hybrid Polymer Composites
Abstract: Hybrid polymer composites are big steps forward in the field of 3D printing. They combine different materials to improve their engineering qualities, usefulness, and use potential. This essay looks at the advanced design and testing methods needed to use 3D printing to make and create mixed polymer materials. First, we look at material design methods, with a focus on choosing plastics and support materials that help the composite have the …
Published in Journal of Polymer & Composites · Vol. 12, Issue 4, 2024 · pp. 22–36 Read article
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Regulations and Standards in the Dairy Industry
Abstract: The dairy industry is a vital component of the global food system, providing essential nutrients to millions of people worldwide. This article offers a comprehensive overview of the regulatory landscape governing dairy products, focusing on quality standards, labeling requirements, and international trade regulations. Quality standards, established by key organizations such as Codex Alimentarius and the International Dairy Federation, ensure that dairy products meet specific criteria for fat and protein content, …
Published in Research and Reviews : Journal of Dairy Science and Technology · Vol. 13, Issue 2, 2024 · pp. 13–17 Read article
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Numerical Solution of Ordinary Differential Equation and Solution of Partial Differential Equation
Abstract: This research paper explores the fundamental role of various mathematical concepts in engineering and scientific fields like aerospace engineering, materials science, software development, and the energy sector. We delve into the applications of solving algebraic and transcendental equations, finite difference interpolation, numerical methods, solutions to ordinary differential equations (ODEs), and numerical solutions to partial differential equations (PDEs). By examining their applications in these diverse fields, we illustrate the critical importance …
Published in Journal of Aerospace Engineering & Technology · Vol. 14, Issue 3, 2024 · pp. 12–20 Read article
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Influence of Nozzle Temperature, Nozzle Diameter, and Layer Height on Tensile and Hardness Characteristics of 3D Printed CF-PLA
Abstract: This research investigates the mechanical characterization of CF-PLA (Carbon Fiber-reinforced Polylactic Acid) composite material produced using Fused Deposition Modeling (FDM) technology. The study investigates the impact of different machine parameters, like nozzle temperature, nozzle diameter, and layer height, on the tensile property and hardness of CF-PLA specimens. A total of 27 samples were produced, each with different combinations of nozzle temperature (190°C, 200°C, and 210°C), nozzle diameter (0.4mm, 0.5mm, and …
Published in Journal of Polymer & Composites · Vol. 13, Issue 1, 2025 · pp. 674–681 Read article
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Comprehensive Study of Least Squares Estimation in Fast Fading MIMO-OFDM Systems
Abstract: MIMO-OFDM technology is now the foundation for modern wireless communication systems, allowing dramatic improvements in spectral efficiency, power efficiency, and transmission rate. On the other hand, the least accurate channel estimation is still a critical task, especially when they are in fast-fading environments. This study gives a comprehensive survey of LSE-based approaches and their applications on different fast-fading channel models for MIMO-OFDM systems. Techniques like Pilot Assisted Channel Estimation (PACE), …
Published in Journal of Microwave Engineering and Technologies · Vol. 12, Issue 1, 2025 · pp. 13–21 Read article
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Synthesis of Novel Hybrid Biocomposites and Experimental Investigation of Mechanical Properties
Abstract: As industries increasingly adopt additive manufacturing, the demand for materials that offer better mechanical properties and functionality is on the rise. The purpose of present research work is to develop a novel hybrid biocomposites for 3D printing applications. The acacia bark, waste powder obtained from wet mahanarayan oil consisting of herbs and other bio filler was added in polylactic acid (PLA) for synthesis of hybrid biocomposites filament by twin screw …
Published in Journal of Polymer & Composites · Vol. 13, Issue 3, 2025 · pp. 1–12 Read article
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Formation and Fabrication of A 3D- Printed Polymer Propeller for Improved Propulsion and Minimal Acoustic Emission: A Comparative Study for Small Unmanned Vehicles
Abstract: The current research focuses on a comparative analysis of propeller designs to identify an option that enhances thrust efficiency while minimizing acoustic noise. The study evaluates three distinct types of propellers: the traditional three-blade propeller, the Sharrow propeller, and a novel aero propeller featuring an air foil-shaped cross-section. To facilitate a hands-on analysis, these propellers were produced using 3D printing technology, specifically employing ABS filament through a Fused Deposition Modelling …
Published in Journal of Polymer & Composites · Vol. 13, Issue 2, 2025 · pp. 252–261 Read article
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Comparative Analysis of 3D-Printed and Molded Shape-Stabilized Phase Change Composites
Abstract: Thermal energy storage (TES) has become essential for efficiently storing and utilizing thermal energy across applications like industrial heating, power plants, batteries, medical devices, food preservation, and aerospace technology. Because of their high energy density, affordability, and environmental friendliness, phase change materials, or PCMs, are employed extensively. However, challenges like poor thermal conductivity and leakage limit their performance. To address these issues, 3D printing has emerged as a powerful tool …
Published in Journal of Polymer & Composites · Vol. 13, Issue 3, 2025 · pp. 184–192 Read article
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Melanoma Skin Cancer Detection Using Deep Learning
Abstract: Cancer as one of the major diseases rank in the World is still very challenging to diagnose and treat hence need for the technological advancements. Chemotherapy, radiation, as well as surgery therapies have several drawbacks including non-selective action, damage to healthy tissues, and multi-drug resistance. Smart nano-theranostics, an advanced integration of nanotechnology with diagnostic and therapeutic modalities, offers a next-generation approach for precision oncology. Thus, the development of multifunctional nanoparticles …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 14, Issue 2, 2025 Read article
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ML-Based Predictive Modeling of Mechanical Properties in 3D-Printed Polymer Composites for IoT Applications
Abstract: This study aims to develop an interpretable and high-accuracy machine learning framework for predicting the mechanical properties of 3D-printed fiber-reinforced polymer composites, with a focus on structure–property correlations relevant to polymer processing and functional performance. Composite specimens based on PLA and ABS matrices were fabricated using FDM with varying weight fractions (5–20 wt%) of carbon and glass fibers. Standardized mechanical testing (ASTM D638, D256, D790) was performed to evaluate tensile …
Published in Journal of Polymer & Composites · Vol. 13, Issue 4, 2025 · pp. 61–78 Read article
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Perspectives of 3D-Printed Polylactic Acid-Based Composites Reinforced with Natural Fibers
Abstract: The growing demand for sustainable and biodegradable materials has led to the development of polylactic acid (PLA)-based composites reinforced with natural fibers. This study investigates the mechanical, thermal, printability, and environmental performance of 3D-printed PLA/Natural Fiber composites, addressing key challenges in fiber-matrix compatibility, structural integrity, and biodegradability. Natural fiber reinforcement enhanced Young’s modulus and flexural strength, but excessive fiber content led to agglomeration, reduced tensile strength, and increased brittleness. Thermal …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 649–664 Read article
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3D-Printed Polymeric Drug Delivery Systems for Personalized Medicine
Abstract: Personalized medicine has revolutionized healthcare by tailoring treatments to individual patient needs. Among the emerging technologies, 3D printing has demonstrated immense potential in fabricating polymeric drug delivery systems with precise control over drug release, dosage, and bioavailability. These systems offer customized therapeutic solutions, improving efficacy while reducing adverse effects. This paper provides an overview of 3D-printed polymeric drug delivery systems, discussing the types of polymers used, fabrication techniques, applications in …
Published in Journal of Polymer & Composites · Vol. 13, Issue 4, 2025 · pp. 313–325 Read article
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Review article on Quality Control in Clinical Trials
Abstract: Quality control (QC) is a critical component in the conduct of clinical trials, ensuring the accuracy, reliability, and credibility of data collected throughout the study. It encompasses a systematic set of procedures designed to monitor trial conduct and data integrity, thus safeguarding the rights, safety, and well-being of participants. This review explores the principles, implementation, and evolving practices of quality control in clinical trials, highlighting its importance across all phases …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 12, Issue 3, 2025 · pp. 01–07 Read article
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Gene Therapy 2.0: Harnessing Cutting-Edge Technologies for Precision Medicine
Abstract: Somatic gene therapy has become the standard form of gene therapy; this creates the Gene Therapy 2.0 era. This new and distinct time consists in the new-generation genome-editing tools and markers, more efficient systems for gene delivery, and personalized medicine approaches that raise the efficacy and safety of the treatment. Base and prime editing are two types of CRISPR-based gene editing tools have provided high precision and reduced off-target effects …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 3, Issue 2, 2025 Read article