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189 articles for “ADME”
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Review on Local News’s Transition Towards Digital Media
Abstract: The development of a contemporary news web application is centered around delivering a captivating user experience replete with advanced functionalities for consuming news. Tailored for daily newspaper readers, the application offers a seamless blend of reading and auditory experiences, allowing users to listen to news articles. Its dynamic homepage algorithmically curates content based on users' historical searches, presenting them with articles that align with their interests. A real-time comment section …
Published in International Journal of Information Security Engineering · Vol. 2, Issue 1, 2024 · pp. 22–28 Read article
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Development of Formulation for Dry Powder Inhalation of Amino Acids Aimed at Smoking Cessation: A Biomedical Perspective
Abstract: This study aims to develop an effective and compliant therapy targeting the lungs through the strategic utilization of amino acids, which play a crucial role in modulating mood and behavior during activities like smoking. L-Tryptophan and L-Tyrosine were finely micronized within the 2–4 µm range, with lactose serving as a carrier, to create a dry powder inhalation formulation. The combination of these amino acids is anticipated to elicit a synergistic …
Published in International Journal of Biomedical Innovations and Engineering · Vol. 2, Issue 2, 2024 · pp. 18–36 Read article
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Pharmacoinformatic Based Screening Of Phytocompound Epigallocatechin Gallate To Identify As A Potential Bcl-2 Inhibitor
Abstract: Objectives: The B-cell lymphoma-2 (Bcl-2) is a protein that is particularly though to be involved in preventing apoptosis. Bcl-2 family members also essential for cancer survival, and its over expression has been linked to tumor genesis, development and resistance to anticancer treatments. The Bcl-2 family of members that inhibit apoptosis is a promising target for the creation of anticancer drugs. Methods: The study was based on computational approach using different …
Published in International Journal of Bioinformatics and Computational Biology Read article
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A Critical Study of Research Challenges for Self-adaptive Software
Abstract: Software systems dealing with distributed applications in changing environments normally require human supervision to proceed with activity in all conditions. These rearranging, investigating, and all in all upkeep errands prompt exorbitant and tedious strategies amid the working stage. These issues are principally because of the open-circle structure regularly followed in programming advancement. Hence, there is popularity for administration many-sided quality decrease, administration mechanization, vigor, and accomplishing the majority of the …
Published in International Journal of Computer Science Languages · Vol. 1, Issue 1, 2023 · pp. 1–6 Read article
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Descriptive Study to Assess the Knowledge Concerning Bio-medical Waste Handling Among B.Sc. Nursing Scholars of Selected Nursing Colleges of District Kangra (H.P)
Abstract: The waste generated from health actions can be dangerous, poisonous, toxic and even mortal because of their high probable for ailment transmission and injury that also outcome in environmental disturbances. The first step to safe disposal of dangerous hospital wastes. an acceptable and proper knowledge of Bio Medical Waste Management among the students of Nursing is important. Appropriate managing of health care waste is then a vital part of environmental …
Published in International Journal of Biomedical Innovations and Engineering · Vol. 1, Issue 1, 2023 · pp. 1–7 Read article
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A Quantitative Study to Assess The Mastery Regarding Breast Feeding among Primi Mothers
Abstract: Background: The study aim to assess the mastery of breastfeeding among primi parous mothers who were admitted to a medical college hospital in Wayanad. Material and methods: This study employed a non-experimental quantitative research methodology, and it involved the selection of 120 primiparous women through purposive sampling. The setting of the study was at DM WIMS the research design was an experimental research design (post-test only control design). The target …
Published in International Journal of Midwifery Nursing And Practices · Vol. 1, Issue 2, 2023 · pp. 24–29 Read article
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Clinical Profile of Dengue Patients who had a Prior Infection with the Covid 19 Virus in a Tertiary Care Centre
Abstract: This cross-sectional analytical study conducted in a tertiary care center aims to investigate the clinical profile of Dengue virus-infected patients with a prior history of COVID-19 within the last three years. Dengue, a prevalent tropical disease, ranges from mild fever to severe conditions like hemorrhagic fever and shock syndrome. The study utilizes the World Health Organization's 2009 classification for Dengue and delineates the febrile, critical, and recovery phases of infection. …
Published in Recent Trends in Infectious Diseases · Vol. 1, Issue 1, 2024 · pp. 34–38 Read article
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Impact of Palliative Care Intervention on Knowledge, Attitude and Practice Regarding Nursing Care Issues in Caregivers of Head and Neck Cancer Patients at Hospice
Abstract: Aim: The primary aim is to assess Knowledge, Attitude, and Practice (KAP) regarding nursing care issues in caregivers of Head and Neck Cancer (HNC) patients admitted at hospice. Secondary aim is to observe the impact of providing information and teaching skills on nursing care issues to caregivers. Materials and methods: A cross-sectional study was prospectively carried out involving 33 caregivers of hospice-admitted patients with head and neck cancer. A self-designed, …
Published in International Journal of Oncological Nursing and Practices · Vol. 1, Issue 2, 2023 · pp. 27–35 Read article
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Answer Checking System Using Artificial Intelligence and Machine Learning: A Review
Abstract: Automatic answer checker software that evaluates and scores written responses in a manner comparable to that of a human. This software programme is designed to evaluate subjective responses provided in an online test and to award points to the user after the answer has been validated. For the sake of the system, you must save the initial response. The administrator is given access to this resource. The system's admin can …
Published in International Journal of Electrical and Communication Engineering Technology · Vol. 1, Issue 1, 2023 · pp. 8–13 Read article
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Adr Caused Byanti-Snake Venom a Case Report Highlighting the Pathophysiology, Prevention, and It’s Management
Abstract: Even in situations where it wasn't necessary, antivenom research was applied to snake bite cases. In order to improve their level of understanding, primary practitioners should receive training on handling envenomation situations as well as current recommendations and references. In cases of snake bites, antivenom must be delivered according to applicable systemic and original indications.More than ten percent of cases with admitted ASV experience some sort of reaction, ranging from …
Published in International Journal of Toxins and Toxics · Vol. 1, Issue 2, 2024 · pp. 40–46 Read article
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Molecular Docking and Interaction of Anthocyanin Derivatives in Regulating Hippo-taz Pathway for Renal Injuries
Abstract: Introduction: The Hippo pathway plays a pivotal role in renal disease, with Yes-associated protein (YAP) exhibiting promise for combined treatments. The crucial evaluation of YAP-targeted drug safety and efficacy through preclinical studies is imperative. Additionally, α-SMA and SMAD3 emerge as potential therapeutic targets in renal fibrosis, driving ongoing research toward innovative interventions. Materials and Methods: In the systematic identification of therapeutic secondary metabolites, Anthocyanin derivatives were methodically retrieved from the …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 2, Issue 1, 2024 · pp. 23–38 Read article
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Assessing Efficacy and Safety: Oxytocin Monotherapy vs. Oxytocin + Carbetocin Combination Therapy
Abstract: Objective: Comparing the Effectiveness between Oxytocin monotherapy and Oxytocin + Carbetocin. Methods: A prospective, non-randomized, observational study focusing on 221 women with CS was conducted. The patients eligible based on inclusion and exclusion criteria were screened and final sample size was 139. Individual patient data including patient demographics, medical history, OT notes, pre and post CBC reports, and safety data were obtained from the patient records. The study compared between …
Published in International Journal of Tropical Medicines · Vol. 1, Issue 1, 2024 · pp. 40–51 Read article
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Assessment of the Efficacy of Demonstration Techniques in Enhancing ASHAs’ Knowledge and Practice of First Aid Management for Dog Bites and Minor Injuries in Rural Bhopal
Abstract: Background: The individuals administering first aid, commonly referred to as first aiders, assume responsibility for the entire situation, including the injured individual and the nature of the injury or illness. They possess the understanding of what actions to avoid, in addition to what actions to take, thus preventing common errors often made by untrained individuals despite good intentions. Furthermore, they recognize that their knowledge and proficiency in first aid can …
Published in International Journal of Community Health Nursing And Practices · Vol. 2, Issue 1, 2024 · pp. 29–46 Read article
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Precision Medicine for Neurofibromatosis Type 1: Progress and Prospects in Drug Discovery
Abstract: Objective: The development of neurofibromas, café-au-lait spots, and other neurological problems are the hallmarks of neurofibromatosis type 1 (NF1), a hereditary disorder. The dearth of efficacious pharmaceutical therapies underscores the need for novel therapeutic approaches, even in the face of clinical variability. Through very accurate prediction of the binding affinity of possible therapeutic drugs with the target protein, the computational technique known as “molecular docking” has become a potent tool …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 2, Issue 1, 2024 · pp. 01–15 Read article
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Evaluating the Impact of a Structured Teaching Program on Knowledge and Attitude Toward the Utilization of Menstrual Cups Among Nursing Students in Chosen Nursing Colleges in Wayanad
Abstract: Introduction: The current investigation aimed to evaluate the impact of a structured teaching program on the knowledge and attitude concerning the utilization of menstrual cups among nursing students in specific nursing colleges in Wayanad. The study objectives included evaluating the knowledge level, assessing the attitude, determining the effectiveness of the structured teaching program on knowledge and attitude regarding menstrual cup usage among nursing students, and exploring any association between pre-test …
Published in International Journal of Midwifery Nursing And Practices · Vol. 2, Issue 1, 2024 · pp. 14–19 Read article
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Effect of Reflex Zone Therapy on Labor Pain Among Antenatal Mothers: A Descriptive Study
Abstract: Background: Pregnancy and childbirth are considered the completion of a woman’s life. Pregnancy is a period of carrying a fetus in the womb of a mother. During the period of 9 months and 7 days, a pregnant woman may undergo several physiological and anatomical changes. Hence pregnancy is a special time of life in a woman’s life. Labor pain is an excruciating pain that lasts for several minutes to hours …
Published in International Journal of Emergency and Trauma Nursing and Practices · Vol. 2, Issue 1, 2024 · pp. 1–6 Read article
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Investigation and Implementation of Internet of Things (IoT) for Different Applications in Library Services
Abstract: The purpose of this study is to explore the uses of the Internet of Things (IoTs) and to identify the obstacles associated with deploying IoTs in libraries. The most of the libraries are using limited IoT-based services. IoTs have enormous promise for libraries, since they may provide various services such as self-checkout and self-return, intelligent querying, smart inventory, and more. In this paper, we have examined the areas where IoT …
Published in International Journal of Radio Frequency Innovations · Vol. 1, Issue 2, 2023 · pp. 18–22 Read article
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Relationship between Socio-Economic Status and New Word Learning
Abstract: New word learning refers to the process of learning of novel words which are not in the vocabulary of the person and it varies as a function of many potent variables. Socio economic status is one of the major variables believed to have a significant effect on new word learning. The aim of the current study to investigate if new word learning varies as a function of socio-economic status. 74 …
Published in International Journal of Education Sciences · Vol. 1, Issue 2, 2024 · pp. 19–24 Read article
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Anticancer Activity of Calotropis procera by Molecular Docking Analysis
Abstract: Cyclin-dependent kinase 2 (CDK2) is a protein synthesized by Calotropis procera. It is known to be responsible for causing cancer in the human body. Studies have presented the significance of the phytochemicals to inhibit the CDK2 protein. Adsorption, distribution, metabolism, and excretion (Swiss ADME) and PubChem were the pharmacological tools which were used to check molecular weight, which should be less than 500D, acceptors less than 10, and donors less …
Published in International Journal of Biochemistry and Biomolecule Research · Vol. 2, Issue 1, 2024 · pp. 01–07 Read article
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Optimized Web-based Online Food Ordering System: Design and Implementation
Abstract: Online food ordering systems have undergone a profound metamorphosis with the advent of digital technologies, catalyzing a pivotal shift in the operational dynamics of the gastronomic sector. This paper elucidates the conceptualization, design, and implementation of an advanced, web-based food ordering system, meticulously engineered to elevate the efficiency and sophistication of food service operations. Employing the rigorously structured Systems Analysis and Design Methodology (SSADM), this system represents a transformative departure …
Published in International Journal of Computer Science Languages · Vol. 2, Issue 2, 2024 · pp. 1–25 Read article