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1680 articles for “BCS Class II/IV drugs”
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The Impact of Artificial Intelligence on the Sales and Marketing of Pharmaceutical Products
Abstract: The rapid development of computing and technology has permeated all branches of science, with artificial intelligence (AI) emerging as a pivotal field in computer science. AI has significantly influenced disciplines ranging from basic engineering to pharmaceuticals. In healthcare and medicinal chemistry, AI applications have become indispensable. Traditional drug discovery approaches are gradually being overtaken by computer-aided drug design. In recent years, artificial intelligence (AI) and machine learning (ML) have become …
Published in Research and Reviews: A Journal of Health Professions · Vol. 15, Issue 1, 2025 · pp. 10–18 Read article
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Synthesis and Evaluation of New Coumarin Derivatives for Inflammatory Bowel Disease Against DSS-Induced Acute Ulcerative Colitis Mice Model
Abstract: Objective: The discovery of the now numerous mouse models of intestinal inflammation has increased our understanding of the intestinal inflammation that occurs in inflammatory bowel disorders (IBD). This study aimed to investigate the use of a standardized animal model subjected to coumarin derivative treatment, and the action of synthesized molecule administration of dextran sodium sulphate (DSS)- induced colitis in experimental mice. Materials and Methods: We generated a variety of unique …
Published in Journal of Modern Chemistry & Chemical Technology Read article
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COVID-19: Nija or Agantuj Roga, Ayurvedic Perspective
Abstract: which is explained under name Janapadodhwamsa or Maraka, It is explained in detail as an independent chapter in various classical texts. As per description Ayurvedic literature described their mechanism of Aetiology (Nidana), various factors affecting severity and actions complicating illnesses along with their management and preventive method. In this article,An attempt is made to describe it as per our classical science, which assert the superiority of host susceptibility (Nija) over …
Published in Research and Reviews: A Journal of Health Professions Read article
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The Concept of Mind and Treatment of Mental Diseases in Homoeopathy
Abstract: Homeopathy treats the patient as a whole in mental and physical plane together based on symptom similarity. Homoeopathy rejects mind-body duality. According to Homoeopathic principles, mind and body are dynamically interconnected. Mental diseases are not separate from so called physical diseases. The classical texts of Homoeopathy have given detailed description of importance of mental symptoms in prescribing suitable similar medicine as well as case taking of mentally ill patients; and …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy Read article
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Pharmacognostical and Phytochemical Study ofAdhahapushpi (Trichodesma Indicum Linn. R. Br.)
Abstract: Objective: To carry out pharmacognostical and phytochemical studies on each part of Adhahapushpi (Trichodesma Indicum Linn. R. Br.) belonging to the family Boraginaceae. Methods: The root, leaf, stem, flower and fruits of Adhahapushpi (Trichodesma Indicum Linn. R. Br.) were assessed for pharmacognostical studies such as macroscopic, microscopy, powder study, and quantitative microscopy. The powder was assessed for proximate analysis like ash value, extracting value, moisture content, elemental analysis, and preliminary …
Published in Research and Reviews : A Journal of Ayurvedic Science, Yoga and Naturopathy Read article
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Extraction, Isolation, Characterization of Curcumin-I From Curcuminoids
Abstract: The major goal of this study is to extract, isolate, and characterize curcumin-I, a component of curcuminoids. Turmeric, or Curcuma longa Linn., plays a significant role in Ayurvedic medicine. Turmeric, or Curcuma longa Linn, is the popular name for this plant. An array of chemicals with biological activity may be more easily extracted with the help of this seasoning. Some of the compounds at play include curcuminoids and turmerone, although …
Published in Journal of Polymer & Composites Read article
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Tiryaq-E-Arba (A Poly Herbal Unani Formulation) in Fighting Against COVID-19 Like Conditions–Unani Perspective
Abstract: Coronavirus disease 2019 (COVID-19) is a pandemic disease of modern time with unique and rapid transmission rate and affected almost all the nations without respecting any border. World Health Organization stated it is an infective disease and pandemic. The coronavirus disease 2019 (COVID- 19) which created in Wuhan, China, has now spread to 192 countries and organizational regions infecting nearly 800,000 persons of all ages as of 31 March 2020. …
Published in Research & Reviews : Journal of Herbal Science Read article
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Introduction to Statistical Tests of Significance
Abstract: Hypothesis examination is the process in which we compare between two differing hypotheses. i.e. the null hypothesis H0 and the alternative hypothesis. As the null hypothesis is examined, a choice is either correct or incorrect. An incorrect conclusion can be produced in two methods: We can deny the null hypothesis once it is true (Type I error) or we cannot succeed to eliminate the null hypothesis when it is incorrect …
Published in Research & Reviews : Journal of Statistics Read article
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Implementation of Data Mining Approach to Find the Adaptability of Students in Online Education during Covid-19 Pandemic
Abstract: The global Covid-19 pandemic has severely affected very aspects of human life, including education. The virus' stunning spread created havoc in the educational system, causing educational institutions to close. As an effect, students must quickly adopt to the change to synchronous online learning. This study identified the different aspects affecting the adaptability level of students in online class. It also identifies the student’s adaptability level in different circumstances in online …
Published in Journal of Artificial Intelligence Research & Advances Read article
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Prediction of Molecular Targets for Anthraquinone and Its Analogs for Treatment of Good Pasteur Syndrome
Abstract: Objective: In order to find prospective molecular targets for the treatment of Good Pasteur Syndrome (GPS), a rare autoimmune disease that affects the kidneys and other organs, computational methods and network pharmacology were applied in this work. The goal of the study is to identify particular human proteins that might interact with anthraquinone and its analogues as well as to uncover potential mechanisms of action by which these drugs might …
Published in International Journal of Bioinformatics and Computational Biology Read article
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Integrating Network Pharmacology and Molecular Docking to Assess Rutin’s Pharmacological Properties
Abstract: Objectives: In the present research, the network pharmacology process was applied to determine the underlying mechanism of the pharmacological properties of Rutin. Network pharmacology was utilized to reveal the interactions between medications and the targets of illnesses, and it is capable of completely articulating the complexity between diseases and medications. The identification of diverse drug-target interactions using network pharmacology may be utilized to discover novel medications for difficult conditions like …
Published in International Journal of Molecular Biotechnological Research · Vol. 1, Issue 1, 2023 · pp. 20–33 Read article
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Melanogenic Inhibitory Effects of Sesamum indicum Phytocompounds Towards CDK 2, c-KIT, and BRAF.
Abstract: Objective: Melanoma is thought to be the fifth most frequent cancer in the US population, despite cancer being the most common cause of death in the globe. BRAF, CDK2, and c-KIT proteins are regarded as potential therapeutic agents since mutations in these proteins are the primary cause of melanoma. For the investigation of their pharmacological properties and therapeutic activities against the target proteins, Sesamum indicum L. and its phytocompounds were …
Published in International Journal of Bioinformatics and Computational Biology Read article
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A Study to Assess Prevalence of Tobacco Use Among Adolescents and Assess the Effectiveness of Structured Teaching Program Regarding Ill Effects of Tobacco Use and Its Prevention Among Adolescents in Selected Community of New Delhi
Abstract: Tobacco use among adolescents has become a global challenge and it is reaching pandemic levels. The objectives of the study were (a) to assess the prevalence of tobacco use among adolescents in a selected community of New Delhi, (b) To provide an organised education programme on the negative effects of tobacco smoking and how to prevent it for teenagers in a chosen New Delhi community, (c) to determine whether the …
Published in International Journal of Community Health Nursing And Practices · Vol. 1, Issue 1, 2023 · pp. 23–38 Read article
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Alzheimer disorders diagnosis system design using machine learning for EEG signal
Abstract: The diagnosis of Alzheimer's disorders (AD), a prevalent neurological disorder, can created by utilising a range of therapeutic methods, including the electroencephalogram (EEG), which has been especially successful in the past. The objective for this study is to develop a computer-aided diagnosis tool which may recognize AD from EEG data. The EEG information was cleaned up with a band-pass elliptic digital filter to remove any interference or disruptions. The filtered …
Published in Journal of Control & Instrumentation Read article
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Baggage Detection and Recognition Using Local Tri-Directional Pattern
Abstract: Nowadays, pattern-based image retrieval algorithms are gaining popularity just because of their uniqueness. There are several issues in the previously proposed systems. The proposed system resolves issues highlighted in the literature. Our proposed system is tested on two image datasets ILIDS and PETS 2006. LTDP provides good results as compared to LBP in baggage detection on two classes that either bag is present or not in an image because LTDP …
Published in International Journal of Mobile Computing Technology · Vol. 1, Issue 1, 2023 · pp. 8–17 Read article
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Activity Quantification of Lu-177 SPECT/CT Imaging for Calibration Factor Analysis in Clinical Radionuclide Dosimetry
Abstract: Purpose: To evaluate the calibration factor (CF) at three-time points with the same protocol & acquisition parameters for the images of Lu-177 activity, scanned by two different SPECT/CTs (GE & MEDISO) using a cylindrical Jaszczak phantom with cold inserts, filled with uniform activity in water and to analyze the changes in the calibration factor data with time. The purpose of the study is to quantitatively analyze the first step (calibration …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 12, Issue 2, 2024 · pp. 9–22 Read article
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Machine Learning Techniques for Predicting Industries Based on Region
Abstract: In recent years, there has been a growing interest and emphasis on agricultural land preparation and its implementation among researchers, primarily due to various factors. These factors include an increased focus within the research community, a rising demand for agricultural land, and the significance of assessing soil health for ensuring robust crop production. Picture request is one such philosophy for soil and land prosperity examination. It is a staggering measure …
Published in International Journal of Algorithms Design and Analysis Review · Vol. 1, Issue 1, 2023 · pp. 1–8 Read article
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Deep Guard: A Comprehensive Deep Learning System for Unmasking Suspicious Activities in Surveillance Footage
Abstract: These days, video surveillance is quite vital. Technology has evolved considerably as machine learning, artificial intelligence, and deep learning become increasingly widespread. There are several algorithms that assist in identifying distinct kinds of suspicious behaviour from live footage by combining the techniques. A person's behaviour is the most unpredictable thing, and it can be quite challenging to determine whether it is normal or suspicious. Video surveillance is automated to address …
Published in International Journal of Satellite Remote Sensing · Vol. 1, Issue 1, 2023 · pp. 23–28 Read article
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Extrapolations of Periwinkle Secondary Metabolites as Multitarget Inhibitor of Breast Cancer Proteins
Abstract: Objective: Breast cancer is considered one of the most common and dangerous forms of cancer. It is a significant public health issue on a global scale. The study estimates that 10.0 million people will die from cancer this year, and 19.3 million people will develop the disease overall (BC). In this computation approach, nowadays emphasizes new drug discovery, the target protein epidermal growth factor receptor (EGFR) (5UGB), estrogen receptor (ER) …
Published in International Journal of Biochemistry and Biomolecule Research · Vol. 1, Issue 1, 2023 · pp. 36–49 Read article
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Tinospora Sinensis Compounds for Zika Virus Targets 5JRZ and 5KVD In Silico Screening: A Potential Approach to Preventing Guillain-Barre Syndrome
Abstract: Objective: GBS is a very rare kind of disease but at the same time, it is very dangerous too. The study estimates that people who are suffering from zika virus infection are more prone to GBS. According to surveys, 1 out of 4000 people got affected by this disease, and the scariest part of this disease is that there is no cure available. In this computational era drug discovery is …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 1, Issue 2, 2023 · pp. 1–15 Read article