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765 articles for “State”
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Pharmacoepigenomics of Replication Timing: How Anti- Cancer Drugs Reshape Chromatin Domains and Mutational Landscapes.
Abstract: DNA replication timing serves as a fundamental epigenetic feature that organizes genome function during the cell cycle (3), while anti-cancer drugs profoundly alter this process to disrupt tumor growth(4). These agents target chromatin architecture, shifting replication domains and reshaping mutational patterns critical for cancer evolution (1,5). DNA replication timing (RT) domains serve as dynamic epigenetic organizers, partitioning the genome into early- and late-replicating regions that correlate with chromatin states, gene …
Published in International Journal of Molecular Biotechnological Research · Vol. 4, Issue 1, 2026 Read article
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Lightweight Models for Per-PC Energy Consumption Forecasting: Comparative Study with ML and DL Approaches
Abstract: We have collected primary data from automated logging of parameters like CPU utilization, estimated power, active or idle state, user logging activity, and the type of day. Additionally, survey data showed user awareness, energy-saving behaviour, and PC usage patterns. The data is pre-processed and merged by applying processes such as data cleaning, normalization, and feature extraction, i.e., determining the peak active timings and downtime. Developed lightweight prediction models based on …
Published in Journal of Alternate Energy Sources & Technologies · Vol. 17, Issue 1, 2026 Read article
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Extracellular Vesicle-Based Liquid Biopsies: Decoding the Tumor Microenvironment for Precision Oncology
Abstract: The tumor microenvironment (TME) plays a pivotal role in cancer initiation, progression, and therapeutic response. Decoding the TME is, therefore, essential for advancing precision oncology. Extracellular vesicles (EVs), including exosomes and microvesicles, are nanoscale lipid bilayer particles secreted by tumor and stromal cells. They transport a wide range of bioactive molecules, such as DNA, RNA, proteins, lipids, and metabolites, which reflect the dynamic state of the TME. Recent advances in …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 15, Issue 1, 2026 · pp. 43–62 Read article
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Data Structure Driven Probabilistic Deadlock Resolution in Multiprocessor Systems
Abstract: Deadlock resolution in multiprocessor systems is fundamentally a graph-theoretic and probabilistic decision problem. Existing victim selection heuristics, such as youngest, oldest, and lowest priority, apply static rules that overlook the dynamic runtime state of processes, leading to unnecessary computational loss. This paper reframes the inference-guided preemption (IGP) algorithm as a data-structure-centric solution, highlighting how resource allocation graphs, wait-for graphs, adjacency lists, min-heaps, and hash-based evidence stores interact to enable efficient …
Published in International Journal of Data Structure Studies · Vol. 4, Issue 1, 2026 · pp. 11–20 Read article
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Spectral Mapping and Tracking Error of MBOC signal and Wavelet based GNSS receiver
Abstract: This research paper delves into the historical evolution and contemporary state of the art in navigation technologies, emphasizing the paramount importance of reliable positioning systems. Tracing the journey from ancient primitive methods to the present-day Global Navigation Satellite Systems (GNSS), with a focus on the Global Positioning System (GPS), the paper explores the diverse instruments and methods developed by civilizations throughout history to determine location and navigate effectively. The main …
Published in Current Trends in Signal Processing · Vol. 16, Issue 1, 2026 Read article
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Influence of Epoxy-Based Thermally Conductive Polymer Composites on the Thermo-Hydraulic Performance of Finned Helical Coil Heat Exchangers Across Flow Regimes
Abstract: The use of polymer composites in heat exchanger applications has gained increasing attention due to their advantages in weight reduction, corrosion resistance, and design flexibility. However, their relatively low thermal conductivity compared to conventional metallic materials remains a key limitation for efficient heat transfer. In this study, the thermo-hydraulic performance of a finned helical coil heat exchanger is investigated with particular focus on epoxy-based polymer composites reinforced with thermally conductive …
Published in Journal of Polymer & Composites · Vol. 14, Issue 2, 2026 · pp. 586–602 Read article
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Enhancement of Flexural Strength in FDM-Printed Components through Taguchi-Based Process Parameter Optimization
Abstract: Additive manufacturing (AM), especially Fused Deposition Modeling (FDM), has emerged as a widely adopted and versatile method for producing three-dimensional components. The process involves the deposition of a thermoplastic filament in a semi-molten state, which solidifies in successive layers to form the final structure. While this method enables the production of complex geometries at relatively low cost, the printed parts often exhibit inferior surface quality and reduced mechanical performance compared …
Published in Journal of Polymer & Composites · Vol. 14, Issue 2, 2026 · pp. 272–280 Read article
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The Importance of Self-Care for Healthcare Professionals in North India: A Regional Analysis of Burnout, Resilience and Institutional Support
Abstract: Background: Burnout in healthcare professionals is described using the framework of Occupational Health and Resilience Theory, where self-care is an individual-level coping mechanism and institutional support is an organizational-level moderator. However, there is a lack of regional data from North India on the structural and contextual factors influencing burnout. Healthcare workers (HCWs) in North India face mounting pressures due to high patient loads, limited mental health resources, and overlapping professional …
Published in International Journal of Behavioral Sciences · Vol. 3, Issue 1, 2026 · pp. 24–29 Read article
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Women Empowerment: The Essential Role of Education for Women in India
Abstract: Education has long been acknowledged as one of the most powerful instruments of social transformation, and in the Indian context, it holds unique significance for women’s empowerment. The empowerment of women is central to reducing gender inequality, dismantling patriarchal norms, and achieving inclusive growth. Women’s education does not merely provide literacy; it develops autonomy, fosters confidence, and equips women with the skills necessary for meaningful participation in social, political, and …
Published in International Journal of Trends in Humanities · Vol. 3, Issue 1, 2026 · pp. 20–24 Read article
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Electrochemical Evaluation of Corrosion Behavior in Industrial Alloys Under Acidic and Marine Conditions
Abstract: Corrosion represents a spontaneous physicochemical transformation in which metals revert to their more stable thermodynamic state, typically oxides, hydroxides, or sulfides, as a result of interaction with environmental elements. Rather than being a simple surface reaction, corrosion is a complex electrochemical phenomenon that significantly influences the durability, reliability, and performance of metallic structures across industrial, marine, and domestic sectors. The consequences extend beyond material degradation, contributing to substantial economic losses, …
Published in Journal of Thin Films, Coating Science Technology & Application · Vol. 13, Issue 1, 2026 · pp. 24–36 Read article
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Multi-Layered AI-Driven Paradigm Shift in IoT Ecosystem Security
Abstract: As the Internet of Things (IoT) continues to weave itself into the fabric of modern life – from smart homes and industrial automation to healthcare and urban infrastructure – the associated security vulnerabilities have become increasingly apparent. Traditional security mechanisms, often built on static rules and perimeter-based defenses, struggle to keep pace with the scale, heterogeneity, and dynamic nature of IoT ecosystems. In response, artificial intelligence (AI) has emerged as …
Published in Journal of Communication Engineering & Systems · Vol. 16, Issue 1, 2026 · pp. 13–21 Read article
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IoT Based Home Automation System using ESP8266 & Google Assistant
Abstract: This research paper discusses a smart home automation system When the Internet of Things is implemented, a simple house can be converted into a smart home with better automation and security. This paper aims to create a voice/text- controlled home application that will help users control their appliances remotely. Switching appliances ON or OFF as per their requirements by just sending text SMS instructions or voice commands. Even if the …
Published in Research & Reviews: A Journal of Embedded System & Applications · Vol. 14, Issue 1, 2025 Read article
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Simple CRM Ticketing Tool
Abstract: The objective of this project is to design and develop a simple customer relationship management (CRM) ticketing tool specifically aimed at small and medium-sized businesses (SMBs) to help streamline customer support operations. The system enables users to raise support tickets for issues, queries, or service requests, which can then be tracked and managed by the support team. Administrators or support staff can assign tickets, update statuses, such as open, in …
Published in E-Commerce for Future & Trends · Vol. 13, Issue 1, 2026 · pp. 1–9 Read article
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Labeling transparency and heavy metal contamination in commercial protein powders: A case study
Abstract: With the recent surge in market demand, health supplements particularly protein powders, have become increasingly vulnerable to quality deterioration, adulteration, and unethical marketing practices. Non-compliance with labeling regulations is on a rise. Moreover, research indicates that heavy metals absorbed from contaminated soil often accumulate in the protein fractions of crops, thereby elevating the risk of heavy metal contamination in protein powders. These issues highlight the urgent need to systematically assess …
Published in International Journal of Nutritions · Vol. 3, Issue 1, 2026 Read article
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Image-Based Crack Morphology Characterisation for Electrical Failure Analysis in Conductive Polymer Composites
Abstract: Electrical performance in conductive polymer composites is strongly governed by crack-network evolution, yet failure analysis typically relies on qualitative image inspection or electrical anomaly detection in isolation. This work proposes an end-to-end framework that converts optical/SEM crack imagery into a standardised crack morphology signature and quantitatively links it to electrical degradation indicators. A two-stage learning strategy is adopted: crack-representation pretraining using the public Concrete Crack Images for Classification dataset, followed …
Published in Journal of Polymer & Composites · Vol. 14, Issue 2, 2026 · pp. 1375-1386 Read article
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Adaptive Task Scheduling And Resource Optimization Using Ai Middleware
Abstract: Modern distributed and heterogeneous computing systems face significant challenges in dealing with dynamically changing workloads, resource fragmentation, and changing latencies; existing traditional, or rule-based, schedulers are no longer useful in achieving the best system performance. Such limitations highlight the importance of the adaptive scheduling paradigms that are able to learn, to forecast and reaction to the real red conditions in the system. The middleware of artificial-intelligence is also an attractive …
Published in Recent Trends in Parallel Computing · Vol. 13, Issue 1, 2026 Read article
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Fibre Orientation and Void Distribution Analysis in Polymer Composite Structures Using Image Processing
Abstract: Fibre orientation and void distribution are critical microstructural features that govern the mechanical performance and reliability of polymer composite materials. Accurate and simultaneous characterisation of these features remains challenging due to their complex spatial interactions and dependence on processing conditions. In this work, an integrated image-processing framework is proposed for the quantitative analysis of fiber orientation and void distribution in polymer composite structures. High-resolution composite microstructure images are processed through …
Published in Journal of Polymer & Composites · Vol. 14, Issue 2, 2026 · pp. 925–933 Read article
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Vitamin D Mitigates Inflammation and Downregulates Importin α3 in Non-Alcoholic Fatty Liver Disease (NAFLD)
Abstract: Background: Pro-inflammatory cytokines, such as TNF-α, IL-1β, IL-6, and IL-8, seem to play a crucial role in the progression of NAFLD as they activate the transcription factor NF-кB. The activated NF-кBp50/RelA subunits are translocated to the nucleus by Importin α3 and Importin α4. Numerous studies have indicated a negative association between NAFLD and vitamin D levels. Low vitamin D levels have been correlated with histological severity, necro-inflammation, and fibrosis in …
Published in International Journal of Cheminformatics · Vol. 4, Issue 1, 2026 · pp. 1–16 Read article
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Determination of Compatibility of Polymer Systems and Study of Chemical Properties of their Mixtures
Abstract: We have obtained mechanical strength of materials as a result not by synthesizing new polymers, but by using industrial polymers. We have developed a technology for obtaining new composite materials based on industrial multi-tonnage polymers of high-strength polyethylene (HSPE), polyvinyl chloride (PVC), polyurethane thermoplastic elastomer (DUTEP), butyl rubber (BR), chlorocarboxylate polyethylene (CCPE), ethylene propylene rubber (EPR). To obtain a composition from these polymers, their mixture compatibility was first determined using …
Published in International Journal of Cheminformatics · Vol. 4, Issue 1, 2026 · pp. 17–29 Read article
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Thermo-Mechanical Vibration Analysis of Simply Supported Laminated and Flat Plates Under Harmonic Loading
Abstract: This paper delves into a numerical exploration of the vibration characteristics and frequency response of two types of plates: a simply supported rectangular laminated plate and a simply supported flat plate. These plates are subjected to concentrated harmonic forces within a thermal environment. The determination of the critical buckling temperature guides the assessment of thermal load effects. Analytical formulations, incorporating first-order shear deformation theory (FSDT) to consider shear deformation and …
Published in Journal of Polymer & Composites · Vol. 14, Issue 2, 2026 · pp. 1519–1530 Read article