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1911 articles for “Active” (ranking capped at the first 2,000 matches — narrow the search to see the rest)
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Evaluation of Bioactive Compounds and Antibacterial Effect of Xanthium Indicum
Abstract: AbstractXanthium indicum L. is a common herbaceous weed found in India. One gram of the plant leaf was taken and different biochemical constituents, viz., moisture content, total carbohydrates, chlorophyll, free fatty acid, glucose, total lipid, protein, amino acid, calcium ascorbic acid and total alkaloid were estimated. The results indicated that significantly low levels of moisture content, total carbohydrates, chlorophyll and free fatty acid were present in the plant material. At …
Published in Research & Reviews : Journal of Herbal Science · Vol. 3, Issue 2, 2014 · pp. 25–29 Read article
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Antiurolithiatic Bioactives from Rotula aquatica Lour
Abstract: Urolithiasis is a complex process of kidney stone formation involves various stages of nucleation and mineralization. Plants are used for treatment of urolithiasis from early times. Thus the study was evolved around the plant Rotula aquatica Lour. used as “Paashanabhedha”. The present study reveals the bioactivity guided isolation of anti-urolithiatic compounds from successive solvent extracts of the roots of Rotula aquatica Lour. The isolated compounds showed significant in-vitro antiurolithiatic activity …
Published in Research & Reviews : Journal of Herbal Science · Vol. 8, Issue 1, 2019 · pp. 1–10 Read article
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Study the Effect of Antioxidant and Antidiabetic Property of the Selective Indian Herbal Plant Extract (A. indicum) on Type II Diabetes Mellitus
Abstract: Abutilon indicum (A. indicum) is a traditional Indian phytomedicine plant used for the treatment of several diseases such as diabetes mellitus, cardiac diseases and anti-inflammatory diseases. The aim of the study was to evaluate whether A. indicum improves insulin sensitivity and determine its active role in bioactive secondary metabolites. Aldose reductase is an enzyme which contains lower affinity towards glucose and helps in converting glucose to sorbitol and slightly catalyzed. …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 9, Issue 1, 2019 · pp. 53–63 Read article
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A Review on Ocimum Sanctum (Tulsi) and its Medicinal Properties
Abstract: Ocimum sanctum (Tulsi) is one of the most important plants mentioned in Ayurveda due to its religious values and enormous medicinal properties. It belongs to Lamiaceae family. Tulsi is an inexpensive, safe and easily available plant commonly found in all the Indian Hindu households. It is a sacred plant in Hindu belief and the offering of its leaves is mandatory in ritualistic worship. Plant parts like leaves, seeds and roots …
Published in Research & Reviews : Journal of Herbal Science · Vol. 10, Issue 3, 2021 · pp. 4–7 Read article
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Smilax zeylanica linn: Pharmacognostic, Taxonomical and Phytochemical Status
Abstract: Plants have always been a center of attraction since ancient times and widely exploited for various needs by humans. Smilax zeylanica linn is a small woody climber belonging to the family Smilacaceae. Smilax china, a very well-known plant used for production of Sarsaparilla is also a member of this family. Thus S. zeylanica is used as a substitute for S. china for obtaining sarsaparilla or chopachini. From the leaves up …
Published in Research & Reviews : Journal of Herbal Science · Vol. 11, Issue 1, 2022 · pp. 1–14 Read article
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Critical Guidelines for TiO2 and Ultraviolet Light Induced Disinfection in Upper Ceiling Mounted Device
Abstract: In-room air cleaners and upper room air UV light germicidal irradiation are designing control technologies that can assist with lessening the groupings of airborne microscopic organisms and contagious spores in the indoor climate. The upper ceiling mounted device is sealed with TiO2 and UV light which is efficient in action due to photocatalytic activity. TiO2 absorbs UV light strongly as compared to sun light and they form hydroxyl radicals. It …
Published in Research & Reviews : Journal of Physics · Vol. 10, Issue 3, 2021 · pp. 30–35 Read article
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Synthesis and Antimicrobial Evaluation of Novel Benzimidazolyl Chalcones
Abstract: A new synthesis of benzimidazolyl chalcones derivatives of N1-[4-(1H-benzo[d]imidazol-2-yl) phenyl] derivatives were synthesized. These compounds have been characterized by detailed IR and NMR spectral analysis and have been screened for their antimicrobial activity in-vitro against bacterial Strains of Escherichia coli, Pseudomonas aeruginosa, Klebsiella pneumonia, Staphylococcus aureus, and Bacillus subtelis, and fungal strains of Aspergillus niger and Candida albicans were used. Most of the tested compounds exploited potent antimicrobial activity with …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 4, Issue 3, 2017 · pp. 22–29 Read article
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Modulation of Receptor Proteins: A Recent Paradigm in Drug Discovery and Target
Abstract: The main aim in drug discovery is to design different ligands those work on specific drug targets. However, various effective drugs work through the modulation of many proteins than single target. Advancement in system biology are establishing a phenotypic strength and a network structure, which suggests that, the excellent selective compounds may be performed less than desired clinical efficacy in comparison to multi-target drugs. In this new appreciation of the …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 5, Issue 1, 2018 · pp. 14–24 Read article
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Assessment and In Vitro Studies of Potent Amylase Inhibitor from Different Plant Species
Abstract: Flavonoids are naturally occurring compounds widely distributed in plants, which have hypoglycemic potential. Amylase inhibitors belong to flavonoids that block amylases which are involved in hydrolyzing the carbohydrates to yield low molecular weight dextrin and sugars. Inhibition of α-amylase along with α-glucosidase can significantly reduce the post-prandial increase of blood glucose and can be an important strategy in the control of blood glucose level in the type-2 diabetic patients. In …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 5, Issue 2, 2018 · pp. 1–6 Read article
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‘Dzumsa’ in Lachung, North Sikkim in India and its role in Shingba Rhododendron Sanctuary
Abstract: The indigenous people residing in the Lachung, North Sikkim are called Lachungpa. The community of Lachungpa has the traditional institution called Dzumsa. This is the social administrative institution bestowed with power to executive the development activities and implements decision in the area. Under the purview of Dzumsa and the Forest Development Agency, the development activities are undertaken in the Shinga Rhododendron Sanctuary, Sikkim, India. Some data obtained in the microplanning …
Published in Research and Reviews : Journal of Veterinary Science and Technology · Vol. 12, Issue 3, 2023 · pp. 1–6 Read article
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Chromosomal Aberration and Mutagenicity Toxicological Studies of Beta-Sitosterol Isolated from Ocimum gratissimum (Lamiaceae)
Abstract: Ocimum gratissimum is an important medicinal plant belonging to the Lamiaceae family. Ocimum gratissimum is a small erect or straggling tree or large, woody, climbing shrub found almost throughout India including Andaman and Nicobar Islands. Stem have been used in antifertility treatment in the indigenous system of medicine, and further clinical tests substantiated their efficacy. The root bark contains diketones, fatty matter, rubber, dulcitol, Beta-sitosterol, phlobatannin and glycosidal tannins. Stem …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 4, Issue 2, 2017 · pp. 1–6 Read article
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A Review on Different Species of Echinacea
Abstract: Echinacea is one of the plant species found in the North American tribes, which are commonly called as coneflowers. Echinacea species such as Echinacea angustifolia, Echinacea pallida, Echinacea purpurea, Echinacea serotina, etc. are used in the treatment of common cold, urinary tract infections, respiratory problems, etc. They also show anti-immunosupperssant activity, anti-viral activity, antifungal activity, anti-inflammatory activity, antioxidant activity, etc. This article mainly includes morphological features, chemical constituents, pharmacology, and …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 6, Issue 1, 2019 · pp. 1–6 Read article
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Preparation of Oral Gels Containing Ethanolic Extract of anacardiumoccidentale L and Characterization
Abstract: The anti-microbial activity of gel containing Anacardiumoccidentale L. leaf extract was investigated. A total of four formulations (ST1–ST4) and a control (without leaf extract) were prepared. All the formulations were evaluated for physical appearance and physical properties of gel like pH, viscosity, spreadability and extrudability. The results of all the physical parameters of the gel were found to be within the limits. All the four formulations including control were evaluated …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 2, Issue 3, 2015 · pp. 16–20 Read article
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Phyto-chemical Screening, In Vitro Anti-arthritic Study, Formulation and Evaluation of Ethanolic Extract of Helicteres Isora Fruits
Abstract: The present investigation was aimed at exploring the anti-arthritic activity of ethanolic extract of Helicteres isora fruits, using Bovine serum albumin (BSA) and Egg albumin denaturation method. The extract was subjected to preliminary phyto-chemical screening in order to find out the major phyto-constituents present in it. Various concentrations of the extract (100, 250, and 1000 μg/ml) were prepared and the percentage inhibition of protein denaturation was determined. Diclofenac sodium (100, …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 10, Issue 1, 2020 · pp. 34–40 Read article
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Potential Application of Retama sphaerocarpa Plant in Pharmaceuticals
Abstract: The aim of this study was to evaluate the phytochemical and biological activity (antibacterial and antifungal) of Retama sphaerocarpa plant and the possibility to use it in pharmaceutical formulations. This plant is traditionally used only as healing remedies because of their antiseptic, antipyretic and antidiarrheal properties. Phytochemical screening of leaves and stems revealed the presence of flavonoids, alkaloids, tannins and steroids. The antimicrobial activity was determined on bacterial strains such …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 9, Issue 3, 2019 · pp. 22–28 Read article
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Antimicrobial Potential of Methanolic Extract of Barringtonia acutangula (L.) Gaertn Fruits
Abstract: Barringtonia acutangula is a middle-sized plant which is distributed in Meghalaya, Assam, West Bengal, Madhya Pradesh, Bihar and Odisha, used in treatment of various ailments. The present work has investigated the antimicrobial activity of methanol extract of Barringtonia acutangula fruit against six resistance bacterial strains such as Enterococcus faecalis, Staphylococcus aureus, Acinetobacter bumannii (Gram positive) and Citrobacter freundii, Enterobacter aerogenes, Escherichia coli (Gram negative). The antibacterial activity was evaluated by …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 3, Issue 3, 2016 · pp. 13–18 Read article
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Mechanistic Studies on Aziridinyl-Benzoquinones in Cultured Tumour Cells
Abstract: This study compares the anti-tumour effects of NQO1 activated drug RH1 (2, 5-diaziridinyl-3 - hydoxymethyl-6-methyl-1, 4-benzoquinone) with a lipophilic ester derivative Es5 on the isogenic cell lines MDA 468 and MDA 468 NQO1 which differs only in expression of wtNQO1. A 39- fold enhancement of growth inhibitory activity was seen in NQO1 expressing cells compared the NQO1 null cells for the Es5 compared to the 25- fold increase seen for …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 11, Issue 2, 2023 · pp. 37–45 Read article
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Studies on Extraction of Flavonoids from Peel of Zingiber officinale
Abstract: Flavonoids are found in every part of the plant. These are separated from extraction process for preparation of drugs and pharmacological activities. In this research, bio flavonoids were enhanced from peel of Zingiber officinale. The optimitization of physico-chemical parameters are involved for extraction of bio flavonoids. Different Solvents, percentage solvents, time and particle mesh sizes are associated to the extraction process of flavonoids. In the extraction, the optimum parameters of …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 12, Issue 1, 2022 · pp. 5–10 Read article
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Current Trends in Crossing the Blood–Brain Barrier: A Review
Abstract: The blood-brain barrier (BBB) is a protective barrier that protects the central nervous system (CNS) from toxins and pathogens in the blood. However, the existence of BBB challenges therapy for CNS diseases and disorders as most pharmaceuticals (drugs) are restricted to enter brain. The review article focuses on the approaches involved to cross BBB with various advanced technology such as nanoparticles, intraventricular injection, chemical modifications, virus mediated distribution, exosome mediated …
Published in Trends in Drug Delivery · Vol. 10, Issue 2, 2023 · pp. 25–38 Read article
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A Review on Manihot Esculenta Species
Abstract: Manihot esculenta, which is commonly known as Cassava, is a woody shrub that provides a high source of carbohydrate. It is an annual crop native to tropical and subtropical regions of the world. Nigeria is the largest producer of the cassava plant. The parts of the plant like leaves, roots, stems, etc are consumed in a variety of ways as they have been shown to possess activities like analgesic, anti-inflammatory …
Published in Research & Reviews : Journal of Botany · Vol. 10, Issue 4, 2021 · pp. 6–10 Read article