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1325 articles for “limitations”
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Nanocarrier-mediated CRISPR/Cas9 Gene Editing of BMP2 for Bone Repair
Abstract: The growth factor that plays an important role in the formation and repair of bones is bone morphogenetic protein 2(BMP2). Nevertheless, because BMP2 is rapidly degrading and has less than half the time to live, its delivery into bone defects may be difficult. A plan to develop a nanocarrier via CRISPRCas9 gene editing mechanism for the delivery of BMP2 into bone defects is outlined in this research proposal. The system …
Published in International Journal of Advance in Molecular Engineering · Vol. 3, Issue 1, 2025 · pp. 14–21 Read article
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Optimized Design and Control of Oil Exploitation Strategies: An Assisted Approach
Abstract: Because there are so many factors and scenarios to consider, optimizing oil exploitation tactics requires complicated decision-making. Conventional approaches frequently concentrate on particular elements of the design infrastructure, which restricts their capacity to fully handle the process. In order to maximize a set of oil exploitation variables in a hierarchical fashion, this research proposes a novel assisted optimization technique that combines mathematical algorithms with engineering analysis. By grouping variables into …
Published in Journal of Petroleum Engineering & Technology · Vol. 15, Issue 1, 2025 · pp. 29–34 Read article
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The Impact of Arthritis on Quality of Life: A Comprehensive Review
Abstract: Arthritis, a group of over 100 joint disorders, is characterized by chronic inflammation that leads to pain, reduced mobility, and disability. As the aging global population grows, the prevalence of arthritis, particularly osteoarthritis (OA) and rheumatoid arthritis (RA), continues to rise. Significant psychological, social, and financial difficulties are among the many ways that arthritis affects quality of life (QoL), in addition to physical health. Joint stiffness, discomfort, and deformities that …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 15, Issue 1, 2025 · pp. 48–52 Read article
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Intrinsic Evaluation of Graph Embeddings: Assessing Clustering and Community Detection Performance
Abstract: This paper presents an intrinsic evaluation of some graph embedding techniques on clustering and community detection tasks. We analyze a diverse set of embedding methods, ranging from traditional techniques such as Laplacian eigenmaps to more recent approaches like graph autoencoders, high-order proximity preserved embedding (HOPE), and graph attention network (GAT), using two widely studied datasets, Cora and CiteSeer. Our evaluation relies on two main metrics: Silhouette score with respect to …
Published in International Journal of Algorithms Design and Analysis Review · Vol. 3, Issue 1, 2025 · pp. 40–48 Read article
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Applying Kruskal's Algorithm in Supply Chain Management for Cost-Effective Network Optimization
Abstract: Transportation route optimization and cost reduction are major difficulties in today's dynamic and complicated supply chain systems. To produce economical and effective network designs, this study investigates the use of Kruskal's algorithm for supply chain network optimization. The algorithm guarantees that all supply chain nodes, including delivery hubs, warehouses, and distribution centers, relate to the lowest possible total transportation cost by building the minimum spanning tree (MST). The study shows …
Published in International Journal of Algorithms Design and Analysis Review · Vol. 3, Issue 1, 2025 · pp. 49–54 Read article
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Synthesis and Characterization of Sustainable, Low-Cost, Biomass-Derived Carbon Films from Hevea Brasiliensis (Rubber) Wood for Environmentally Friendly Gas Sensors with Enhanced Selectivity and Sensitivity to Polar Vapors and Hazardous Gases
Abstract: Hevea brasiliensis (rubber) wood sawdust was utilized to fabricate carbon gas sensors for detecting 1000 ppm of ethanol, methanol, acetone, carbon dioxide, and ammonia gases. The carbon particles were prepared by phosphoric acid impregnation followed by thermal activation and then fabricated into films on conductive and non-conductive substrates using the doctor blade method. X-ray diffraction (XRD) analysis revealed distinct graphitic features with peaks at the (002) and (100) planes, indicating …
Published in Journal of Thin Films, Coating Science Technology & Application · Vol. 12, Issue 1, 2025 · pp. 22–36 Read article
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A Comprehensive Review on Deposition Techniques for Functional Thin Films
Abstract: Thin films have become a critical element in the design and development of advanced functional materials because of their remarkable versatility, high efficiency, and ability to be easily integrated into a wide variety of devices. These films are used in a broad range of industries, from electronics to energy, owing to their ability to improve the performance of components by providing tailored electrical, optical, and mechanical properties. The deposition of …
Published in Journal of Thin Films, Coating Science Technology & Application · Vol. 12, Issue 1, 2025 · pp. 1–7 Read article
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Assessment of Irrigation Access, Challenges and Opportunity in Wolaita, Kembata Tembaro and Hadiya Zones of Snnppr, Ethiopia
Abstract: In the Wolaita, Kembata Tembaro, and Hadiya zones, this study evaluated irrigation access and the difficulties that come with it. The data in this study were analyzed using an econometric model in addition to descriptive statistics. The study region yielded both primary and secondary data. For this investigation, the multi-stage sampling technique was used. Using a pre-tested questionnaire, 139 sample household heads were chosen at random and questioned. To support …
Published in International Journal of Rural and Regional Development · Vol. 3, Issue 1, 2025 · pp. 18–28 Read article
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Sign Language-enabled Offline IP-based Video Call Intercom System for the Deaf
Abstract: Individuals who are deaf or hard of hearing frequently encounter major communication challenges on digital platforms because sign language support is often insufficient. This study presents a real-time, internet-independent sign language-to-text translation system embedded in an offline IP-based video intercom, designed to facilitate seamless communication. Leveraging TensorFlow’s Convolutional Neural Network (CNN) for classification and MediaPipe for hand tracking, the system achieved a training accuracy of 94.24% and a validation accuracy …
Published in Journal of Image Processing & Pattern Recognition Progress · Vol. 12, Issue 1, 2025 · pp. 53–66 Read article
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Transfer Learning in Deep Learning Models for Medical Imaging: Utilizing Pretrained Models to Improve Performance in Medical Image Analysis
Abstract: Transfer learning is now a trending technique in deep learning, especially in medical imaging. This technique solves landmark problems by utilizing the pre-trained models, including the limited availability of the annotated medical data and the time-consuming computational costs of training deep learning models from scratch. The generalizability of deep models could increase diagnostic precision for specific medical tasks, require fewer samples to train, and take less time to train due …
Published in Journal of Image Processing & Pattern Recognition Progress · Vol. 12, Issue 1, 2025 · pp. 67–85 Read article
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Millimeter Wave in Internet of Things Connectivity: A Study
Abstract: The internet of things (IoT) is rapidly evolving, connecting billions of devices and transforming industries. However, this growth is stretching the limitations of traditional wireless communication technologies. Enter millimeter wave (mmWave), a high-frequency band promising to revolutionize IoT connectivity by offering significantly higher bandwidth and lower latency. While still in its early stages of implementation, mmWave is poised to become a cornerstone of the next generation of IoT ecosystems. Millimeter …
Published in International Journal of Wireless Security and Networks · Vol. 3, Issue 1, 2025 · pp. 13–23 Read article
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Zero Trust Implementation Challenges in Legacy and Wireless Network Systems
Abstract: This article titled "Zero Trust Implementation Challenges in Legacy Systems and Wireless Network Systems" delves into the evolving landscape of cybersecurity, emphasizing the inadequacy of traditional perimeter-based security models in the face of modern cyber threats. The Zero Trust Security framework is highlighted as an essential advancement in this scenario, emphasizing the core idea of "never trust, always verify." This paradigm shift underscores the importance of continuous verification, least privilege …
Published in International Journal of Wireless Security and Networks · Vol. 3, Issue 1, 2025 · pp. 39–50 Read article
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Visualization of genomic sequence in BRCA1 and BRCA2
Abstract: Heredity is the main reason of breast cancer in women and mutation or genetic variations also another reason for the spread of breast cancer. Heredity and genetic variations are responsible 5%-10%, 30%-50% respectively. There are 90% chances of developing neoplasm by the mutations. The effect of BRCA1 and BRCA2 may leads to the variations in DNA therefore it should be in limited amounts so that there will be minimum changes …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 15, Issue 1, 2025 · pp. 49–55 Read article
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AI-Empowered Space Traffic Management: Challenges and Strategies
Abstract: Space traffic management (STM) has emerged as a critical field of study due to the rapid expansion of space activities, including satellites, debris, and future crewed missions. This research paper delves into the multifaceted issues and challenges associated with STM and explores innovative strategies, specifically focusing on integrating artificial intelligence (AI). It examines the pressing problems of space debris proliferation, collision avoidance, spectrum congestion, and the need for international cooperation. …
Published in Research & Reviews : Journal of Space Science & Technology · Vol. 14, Issue 1, 2025 · pp. 20–28 Read article
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Nano Positioning for Large Scanning Range for XY Mechanism
Abstract: In this study, an XY flexure stage that provides a variety of motion options while reducing incorrect motions is designed and assessed. In the flexure design, the double parallelogram flexure modules are positioned methodically and symmetrically. The performance of the flexure stage is assessed using finite element analysis, and experimental testing is performed to validate the findings. The built-in prototype of the flexure stage has dimensions of 350 mm x …
Published in Journal of Microelectronics and Solid State Devices · Vol. 12, Issue 1, 2025 · pp. 30–35 Read article
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Why Sheep Matter? A Holistic Perspective on Productive, Social, and Economic Benefits
Abstract: The comparative advantages of raising sheep over goats have significant implications for productive, social, cultural, and economic perspectives in livestock farming systems. Sheep farming offers unique benefits, including superior wool production, higher carcass yields, and greater adaptability to diverse climates and grazing systems. Sheep are more efficient in utilizing low-quality forages, exhibit better reproductive performance with higher lambing percentages, and demonstrate reduced susceptibility to diseases, resulting in lower veterinary costs. …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 15, Issue 2, 2025 · pp. 9–25 Read article
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Excoecaria agallocha Extract from Leaves Encounters Antifungal, Antibacterial, and Cytotoxic Activity – In Vitro Studies
Abstract: Mangroves contain a wide range of bioactive substances, certain of and these have been used as solutions for a variation of conditions for thousands of years. Excoecaria agallocha leaf application components have been extracted in the presence of organic solvents along with water-based with a Soxhlet apparatus and antibacterial research properties employing diffusion agar well assays towards nine different kinds of culture infectious agents, six clinical trials isolated compounds, as …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 15, Issue 2, 2025 · pp. 1–7 Read article
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Heterosis in Plants
Abstract: It refers to hybrid vigor or heterosis; herein, the offspring expressed better traits than one or both parent lines. This most often manifests in crop breeding as increased yield in F1 hybrids compared with their parents. Developing high-yielding hybrid cultivars across a wider range of crops represents an important strategy for addressing future food security. However, conventional hybrid breeding approaches are fraught with significant challenges in many self-pollinating crops, such …
Published in Research & Reviews : Journal of Botany · Vol. 14, Issue 2, 2025 · pp. 21–31 Read article
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Calotropis: A Comprehensive Review of Its Phytochemistry, Pharmacology, and Therapeutic Potential
Abstract: Calotropis gigantea is a genus in the family Apocynaceae that grows in tropical and semitropical climates. India is home to this plant’s distribution. In Hindi, it is referred to as sweta arka. It is well known for its medicinal and ethnobotanical values. Calotropis gigantea, in particular, has a history of use in the treatment of many health-related issues, including disorders of the respiratory system, inflammation, and skin infections. Calotropis gigantea …
Published in Research & Reviews : Journal of Botany · Vol. 14, Issue 2, 2025 · pp. 6–20 Read article
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Participatory Demonstration of Grass Strips as Biological Soil and Water Conservation Measures in Kamba Woreda, South Ethiopia
Abstract: Land degradation due to soil erosion and soil fertility depletion is a significant threat to the agricultural system, limiting food security and sustainable agricultural production. This study demonstrated Desho grass strips as biological soil and water conservation measures in Kamba woreda Gamo zone south Ethiopia. Six (6) nearby trial farmers who took part in the demonstration directly were chosen for the study using the purposive sample technique. Sole maize and …
Published in International Journal of Land · Vol. 1, Issue 1, 2024 · pp. 1–10 Read article