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634 articles for “B-Cell”
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Long-Term Effects of Feeding High-Lignin Forage to Ruminants: Implications for Productivity, Health, and Sustainability
Abstract: The long-term feeding of high-lignin forage to ruminants can significantly impact various aspects of animal performance, health, and environmental sustainability. Lignin, a complex phenolic compound present in plant cell walls, is indigestible by rumen microbes, leading to reduced fiber digestibility and decreased nutrient utilization. Over time, feeding ruminants with forages high in lignin results in a decline in voluntary dry matter intake (DMI), inefficient energy and protein absorption, and suboptimal …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 15, Issue 3, 2025 · pp. 30–45 Read article
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Study of Multiple Modules Solar System Electricity Generation
Abstract: Solar energy is a sustainable, non-depleting, and ecologically safe energy source that originates from sunlight. Every hour, the globe receives enough solar energy to meet its energy demands for a whole year. In the current world, we need power on a regular basis. This solar energy is used in commercial, residential, and industrial settings. It readily absorbs energy from direct sunlight. In this post, we looked at solar energy from …
Published in Journal of Power Electronics and Power Systems · Vol. 16, Issue 1, 2026 · pp. 25–32 Read article
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Formulation and Evaluation of Transdermal Patch to Enhance Treatment of Alopecia
Abstract: The improvement of novel topical sedate conveyance frameworks has picked up noteworthy consideration due to their potential in upgrading the helpful viability and persistent compliance whereas minimizing systemic side impacts. This thinks about centers on the definition and assessment of transdermal patches planned to discharge allicin, the essential naturally dynamic compound determined from garlic (Allium sativum) extricate. Allicin is eminent for its wide range of pharmacological properties, counting antimicrobial, anti-inflammatory, …
Published in Trends in Drug Delivery · Vol. 12, Issue 2, 2025 · pp. 20–33 Read article
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Foliar Application of Zinc Nanoparticles Improves Photosynthetic Performance in Wheat Plants
Abstract: The present study investigated the impact of foliar spray of zinc oxide nanoparticles on physiological and biochemical reactions in wheat (Triticum aestivum L.) Foliar spray with zinc oxide nanoparticles at 10 mg/l positively increased pigment content and biomass in comparison to control while a significant reduction in chlorophyll content and biomass accumulation was observed at higher concentration of 1000 mg/l. A study of Chlorophyll a fluorescence parameters at 10 mg/l …
Published in Research and Reviews : A Journal of Biotechnology Read article
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Histological Effects of the Antibiotic Gentamicin on the Ovarian Tissue of Female White Laboratory Rats
Abstract: This study aimed to evaluate the histological alterations induced by Gentamicin in the ovarian tissue of white laboratory rats. A total of 12 adult female rats were used and randomly divided into two groups, with each group consisting of six animals. The experimental group received Gentamicin at a dose of 120 mg/kg body weight administered as an injection once daily, while the control group received an equivalent volume of normal …
Published in International Journal of Antibiotics · Vol. 3, Issue 1, 2026 · pp. 1–8 Read article
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Vitamin D Mitigates Inflammation and Downregulates Importin α3 in Non-Alcoholic Fatty Liver Disease (NAFLD)
Abstract: Non-alcoholic fatty liver disease (NAFLD) affects about one-third of the population in the United States and Western countries, reaching up to 90% among obese individuals and those undergoing bariatric surgery. Characterized by hepatic fat accumulation, NAFLD progresses from simple steatosis to non-alcoholic steatohepatitis (NASH), fibrosis, and, in rare cases, hepatocellular carcinoma. Linked intricately with metabolic syndrome, including diabetes and obesity, NAFLD development involves insulin resistance and hyperinsulinemia. Experimental evidence consistently …
Published in International Journal of Cheminformatics · Vol. 4, Issue 1, 2026 Read article
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Vitamin D Mitigates Inflammation and Downregulates Importin α3 in Non-Alcoholic Fatty Liver Disease (NAFLD)
Abstract: Background: Pro-inflammatory cytokines, such as TNF-α, IL-1β, IL-6, and IL-8, seem to play a crucial role in the progression of NAFLD as they activate the transcription factor NF-кB. The activated NF-кBp50/RelA subunits are translocated to the nucleus by Importin α3 and Importin α4. Numerous studies have indicated a negative association between NAFLD and vitamin D levels. Low vitamin D levels have been correlated with histological severity, necro-inflammation, and fibrosis in …
Published in International Journal of Cheminformatics · Vol. 4, Issue 1, 2026 · pp. 1–16 Read article
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Inhibition of PI3K/Akt/mTOR Signaling Pathway by Vitis Vinifera Phytocompounds: A Promising Strategy for Supressing Colorectal Cancer Growth and Metastasis
Abstract: Objectives: Colorectal cancer was not typically identified a few decades ago. Today, with almost 900 000 fatalities each year, it is the fourth most dangerous cancer in the world. Colorectal cancer is responsible for about 10% of all cancer diagnoses annually and cancer-related deaths worldwide. It is the second most common type of cancer in women and the third most common type in men. Incidence and death are roughly 25% …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 1, Issue 2, 2023 · pp. 64–75 Read article
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In Silico Prediction of Multitarget Mechanism of Quinoline and Its Analogs on Phosphoinositide-3-Kinase Pathway Proteins
Abstract: Objective: Phosphoinositide 3-kinases (PI3Ks), the target of rapamycin (PI3K/Akt/mTOR, PAM), are a family of enzymes that play a role in the growth, proliferation, differentiation, motility, survival, and intracellular trafficking of cells, all of which are essential for healthy cellular function and are also connected to cancer. In this study, quinoline and its derivatives were employed to analyze its inhibition activity on the phosphoinositide-3-kinase pathway. Methods: In this work, eight phytocompounds …
Published in International Journal of Molecular Biotechnological Research · Vol. 1, Issue 1, 2023 · pp. 57–76 Read article
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Lung Cancer Detection and Classification Using Deep Learning
Abstract: Lung cancer is a disease that can be effectively treated if detected early. Various technologies, such as magnetic resonance imaging, isotopes, X-rays, and computed tomography scans, are employed for diagnosis. One of the most crucial strategies in combating cancer is early detection, which greatly enhances a patient’s likelihood of survival; this is where artificial intelligence plays a significant role. The approach proposed in this study leverages historical medical data to …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 13, Issue 3, 2024 · pp. 11–17 Read article
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Pharmacoepigenomics of Replication Timing: How Anti- Cancer Drugs Reshape Chromatin Domains and Mutational Landscapes.
Abstract: DNA replication timing serves as a fundamental epigenetic feature that organizes genome function during the cell cycle (3), while anti-cancer drugs profoundly alter this process to disrupt tumor growth(4). These agents target chromatin architecture, shifting replication domains and reshaping mutational patterns critical for cancer evolution (1,5). DNA replication timing (RT) domains serve as dynamic epigenetic organizers, partitioning the genome into early- and late-replicating regions that correlate with chromatin states, gene …
Published in International Journal of Molecular Biotechnological Research · Vol. 4, Issue 1, 2026 Read article
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Health Implications of Electromagnetic Wave Exposure
Abstract: From low-frequency radio waves to high-frequency gamma rays, electromagnetic waves have a wide range of effects on human health. This diverse subject includes an extensive spectrum of waves. The non-thermal effects of low-frequency waves, such as microwaves, are not completely understood despite the fact that they predominantly represent thermal dangers, which could potentially lead to tissue heating and damage similar to those caused by heating. High-frequency radiation, such as gamma …
Published in Research & Reviews : Journal of Physics · Vol. 13, Issue 1, 2024 · pp. 9–13 Read article
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Designing and Developing a Cancer Chatbot in a Website
Abstract: Cancer is a disease that affects millions of people worldwide each year and is characterized by the rapid growth of cells that are abnormal. The outcome is affected since numerous cases are discovered at advanced stages of the disease. Anxiety and depression are two mental health issues that frequently coexist with the illness, worsening its effects on sufferers. There were many medical apps that provide guidelines for patients, but these …
Published in Journal of Multimedia Technology & Recent Advancements · Vol. 11, Issue 1, 2024 · pp. 1–9 Read article
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Evaluating the Impact of the Valsalva Maneuver on Pain Relief During Intravenous Cannulation in Patients at Selected Hospitals in Tirupati, Andhra Pradesh
Abstract: Pain can be defined as an unpleasant tactile sensation, arousing sensory experience, and an emotional response that is linked to any type of tissue, cell, or skin damage. Pain is a very common and a primary reason for which people seek health care. Among all the non-pharmacological methods for pain relieving, the Valsalva maneuver is one of the methods which is found effective in reducing the level of pain a …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 13, Issue 3, 2024 Read article