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1074 articles for “PHA”
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Molecular Docking Analysis of Phytocompounds from Ficus hispida Aagainst Epidermal Growth Factor Receptor Kinase Domain
Abstract: The Epidermal Growth Factor Receptor (EGFR) kinase domain plays a key role in cancer, as it promotes tumour growth and helps cancer cells survive, making it an important focus for developing treatments. Through comprehensive computational analysis, this study investigates the anticancer potential of phytocompounds from Ficus hispida, a medicinal plant renowned for its diverse bioactive compounds, as novel EGFR inhibitors. Molecular docking techniques using Py Rx software were employed to …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 3, Issue 2, 2025 Read article
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Molecular Docking Analysis of Phytocompounds from Ficus hispida Against Epidermal Growth Factor Receptor Kinase Domain
Abstract: The Epidermal Growth Factor Receptor (EGFR) kinase domain plays a key role in cancer, as it promotes tumour growth and helps cancer cells survive, making it an important focus for developing treatments. Through comprehensive computational analysis, this study investigates the anticancer potential of phytocompounds from Ficus hispida, a medicinal plant renowned for its diverse bioactive compounds, as novel EGFR inhibitors. Molecular docking techniques using Py Rx software were employed to …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 3, Issue 2, 2025 · pp. 48–62 Read article
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Solid-State Reactions: Mechanistic Insights, Kinetic Behavior and Emerging Applications in Advanced Materials
Abstract: Solid-state reactions are fundamental to the synthesis and transformation of inorganic materials, playing a crucial role in the development of ceramics, semiconductors, catalysts, and energy storage systems. Unlike reactions in liquid or gaseous phases, they are limited by restricted atomic mobility and typically require elevated temperatures to enhance diffusion and overcome activation energy barriers. These reactions proceed through interfacial contact between solid reactants, followed by nucleation of product phases and …
Published in International Journal of Crystalline Materials · Vol. 3, Issue 1, 2026 · pp. 10–14 Read article
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Using of Rat Model Over Other Species: A Review
Abstract: The first domesticated morphological features to be used in studies were rats. Scientists employed the brown rat Rattus norvegicus to study human biology and therapeutics two decades ago, focusing on the consequences of hunger and oxygen deprivation. Rats have been used to answer a wide range of basic science problems relevant to common human ailments in the fields of pharmacology, immunology, physiology, nutrition, behaviour, learning, and toxicity. The article gives …
Published in International Journal of Animal Biotechnology and Applications Read article
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An Optimize Formulation to Synthesis of size Controlled Hydrophobic Starch Acetate Nanoparticles using Box- Behnken Design
Abstract: The best way to improve the overall performance of native starch is by chemical modification. In recent years, hydrophobically modified starch has attracted considerable attention for the design and manufacture of novel nanoparticulate drug delivery carriers. The purpose of this research was to synthesize hydrophobic starch nanoparticles (NPs) and to optimize process factors through the use of response surface methodology (RSM). The corn starch acetate (CSA) NPs was synthesized using …
Published in Journal of Polymer & Composites Read article
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Concept and Management of Haemorrhoids (Bawaseer) in Unani System of Medicine
Abstract: Haemorrhoids are one of the most prevalent diseases with significant impact on quality of life. Haemorrhoids commonly known as piles are defined as swollen, inflammed veins around the anus or the lower part of rectum. The most common symptom of haemorrhoids is rectal bleeding and discomfort before or after bowel movements. According to the Unani Physicians, the most common cause of the haemorrhoids is the accumulation of the abnormal melancholic …
Published in Research & Reviews : A Journal of Unani, Siddha and Homeopathy Read article
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Studies on Mechanical, Optical, Barrier Properties and Characterization of LDPE-PLA Blend Films with Micro Clay
Abstract: Low density poly ethylene (LDPE) and Poly lactic acid (PLA) in the ratio of 70:30 wt% were blended along with ethylene glycidyl meth acrylate (EGMA) as compatibilizer (2.5%), benzophenone as photodegradable additive (1%) and microclay (1,3,5%) as filler. Blending took place in a twin-screw extruder and then the resulting blend was processed into a film using blown film extrusion. Mechanical, optical, barrier and degradative properties of film were tested as …
Published in Journal of Polymer & Composites Read article
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An Efficient Method of Fault Analysis using Artificial Neural Network
Abstract: In the power system, there are many techniques to identify and classify the faults. So, it is utmost important to choose the suitable technique. In this paper, a novel technique based on ANN have been proposed. When abnormal conditions occur in the system, the purposed method identifies and classify the fault to protect the system from the faults and stop from the big hazards. Simulation of purposed Simulink model have …
Published in Current Trends in Signal Processing Read article
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An Overview of Hybrid Renewable Energy Systems
Abstract: Long-term evaluation and analysis of several factors should be done to propose a full-phase power generation system based on renewable energy sources. An accurate assessment of the potentially available resources should be done like measuring solar irradiation, wind speed, etc. We are designing a hybrid system where hybridization methods entirely consist of renewable energy sources—specifically solar photovoltaic (PV), wind, and gravity systems. Wind and solar are among the popular renewable …
Published in Journal of Alternate Energy Sources & Technologies Read article
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Improved Unified Power Quality Conditioner Design and Numerical Simulation for Power Quality Improvement
Abstract: Harmonic currents can distort the waveform voltage, resulting in a weak signal. There is also an increase in the number of loads requiring enough sinus tension to function properly. As electronic devices become more power-sensitive, people are becoming increasingly interested in power conditioning solutions. Therefore, if the amount of electricity being generated falls below a certain threshold, some type of compensation must be provided. Unified Power Quality Controller (UPQC) is …
Published in Journal of Microwave Engineering and Technologies Read article
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Recombinant Protein Manufacturing Using Actinomycetes as Host Cells
Abstract: Actinobacteria are highly sought-after for use as cell factories or bioreactors in the pharmaceutical, agricultural, industrial, and environmental sectors. The commercial production of these proteins as recombinants and the biochemical and structural characterization of key proteins have been made possible by the genome sequencing of numerous species of actinomycetes. In this regard, better expression vectors that may be used with actinomycetes are required. As discussed in this article, recent developments …
Published in Research & Reviews: A Journal of Bioinformatics Read article
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Performance Analysis of Space Shift Keying and Quadrature Space Shift Keying for MIMO Channels
Abstract: In wireless communication the propagation channel is characterized by multipath propagation due to scattering on different obstacles. MIMO takes advantage of multi-path and uses multiple antennas to send multiple parallel signals from transmitter. “Multi-path” occurs when different signals arrive at the receiver at various times. MIMO exploits the space dimension to improve wireless systems capacity, range and reliability. There are two different modulation techniques that exploits the best features of …
Published in Research & Reviews : Journal of Space Science & Technology Read article
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Status of Open Source Software for Digital Libraries in Telangana (A Study Conducted on Private Colleges)
Abstract: The purpose of this paper is to highlight the importance of digital libraries and digital resources through open source software which is highly in demand in the private colleges of Telangana. This study was conducted in 123 private colleges of Telangana only. These colleges were divided subjectwise like Engineering, Pharmacy, and Management. This paper is based on survey methodology and a sampling technique was used for the collection of data. …
Published in Journal of Advancements in Library Sciences Read article
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Performance Evaluation of Dominant Red Barred D922 Breed at Peri-urban Areas of Gurage Zone in SNNPR of Ethiopia
Abstract: Animal production in general and chickens in particular play important socioeconomic roles. The aim of this study was to evaluate the performance of red barred dual breeds in peri-urban areas of the Gurage zone and to determine the economic feasibility under farmers’ management conditions to promote and disseminate the approved technology packages to the users. Participant farmers were selected purposively on the basis of willingness to cover all associated package …
Published in Research and Reviews : Journal of Veterinary Science and Technology Read article
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A Review on Medicinal Properties of Chickpea and Its Profile
Abstract: Cicer arietinum is the most well-known vegetable and seen everywhere in the world, particularly in Afro-Asian nations. It has a place with family Fabaceae and appropriated in tropical, sub-tropical and calm districts. It is an annual crop with 20–100 cm tallness and the stems are spread, erect while root framework is vigorous and leaves are made of 11–15 individual handouts which are oval fit as a fiddle. The blossoms are …
Published in Research and Reviews : Journal of Crop science and Technology Read article
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Empirical Relation to Predict Essential Oil Yield in Conventional Distillation System
Abstract: Peppermint is medicinal herb, and its extracts (essential oils) are of great importance because they are used in pharmaceutical, food, and cosmetic items. Moreover, peppermint oil is also used as anticancer, anti-bacterial, anti-viral, spasmodic, anti-diabetic, ulcer healing, anti-obesity, etc. Steam distillation method is used to extract essential oil from peppermint. Boiler, extraction unit, condenser and Florentine flask are the main components of steam distillation system. The objective of present study …
Published in Journal of Polymer & Composites Read article
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A Note on Vaccine Design Using Bioinformatics Methods and Applications
Abstract: Vaccines prevent infectious diseases caused by viruses and bacteria saving millions of lives.It consists of certain agents that resemble disease causative agentsand stimulates our immune system to recognize and fight foreign antigens. Immune function or an immune response is the fundamental basis of the vaccine's mechanism. Vaccines are pharmaceutical derivatives that provide an affordable way to prevent diseases.Various bioinformatics approaches can be incorporated into vaccine design studies and development. Reverse …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 1, Issue 1, 2023 · pp. 1–9 Read article
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In Silico Molecular Docking of Indigofera tinctoria Phytocompounds to Target EGFR/ERK and FGFR/FGF Pathway Proteins Involved in Prostate Cancer
Abstract: Objective: Prostate cancer being the second major cause of cancer-related deaths in males, affects the small walnut-shaped gland below the bladder called the prostate gland. The epidermal growth factor protein (EGFR), cascade protein (ERK), and fibroblast growth factor proteins (FGFR and FGF) are involved in the different signaling pathways that lead to the formation of different products, that are responsible for the progression of cancer and thus can be considered …
Published in International Journal of Molecular Biotechnological Research · Vol. 1, Issue 1, 2023 · pp. 34–56 Read article
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Melanogenic Inhibitory Effects of Sesamum indicum Phytocompounds Towards CDK 2, c-KIT, and BRAF.
Abstract: Objective: Melanoma is thought to be the fifth most frequent cancer in the US population, despite cancer being the most common cause of death in the globe. BRAF, CDK2, and c-KIT proteins are regarded as potential therapeutic agents since mutations in these proteins are the primary cause of melanoma. For the investigation of their pharmacological properties and therapeutic activities against the target proteins, Sesamum indicum L. and its phytocompounds were …
Published in International Journal of Bioinformatics and Computational Biology Read article
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In Silico Prediction of Multitarget Mechanism of Quinoline and Its Analogs on Phosphoinositide-3-Kinase Pathway Proteins
Abstract: Objective: Phosphoinositide 3-kinases (PI3Ks), the target of rapamycin (PI3K/Akt/mTOR, PAM), are a family of enzymes that play a role in the growth, proliferation, differentiation, motility, survival, and intracellular trafficking of cells, all of which are essential for healthy cellular function and are also connected to cancer. In this study, quinoline and its derivatives were employed to analyze its inhibition activity on the phosphoinositide-3-kinase pathway. Methods: In this work, eight phytocompounds …
Published in International Journal of Molecular Biotechnological Research · Vol. 1, Issue 1, 2023 · pp. 57–76 Read article