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56 articles for “structural validation”
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Phase – Field Modeling of Brittle and Ductile Fracture Under Complex Loading Conditions
Abstract: Phase-field modeling has emerged as a powerful computational framework for predicting fracture behavior in engineering materials, offering a unified description of crack initiation, propagation, branching, and coalescence without the need for explicit crack tracking. This study presents an in-depth examination of phase-field modeling applied to both brittle and ductile fracture under complex loading conditions, including multiaxial stress states, cyclic loading, thermal gradients, and dynamic impact. The phase-field approach regularizes the …
Published in International Journal of Fracture Mechanics and Damage Science · Vol. 3, Issue 2, 2025 · pp. 13–18 Read article
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InSilico Analysis and Homology Modeling of Tetrahydroprotoberberine Oxide involved in the Berberine Biosynthesis
Abstract: Objective: Berberine, a bioactive compound found in various plant species, exhibits diverse pharmacological properties with potential applications in pharmaceutical research. The biosynthesis of berberine involves several enzymatic steps, with (S)-tetrahydroprotoberberine oxidase playing a pivotal role. This study aimed to elucidate the structural and functional characteristics of (S)-tetrahydroprotoberberine oxidase to better understand its role in berberine biosynthesis and its potential biotechnological applications. Methods: Using bioinformatics tools and computational methods, the physicochemical …
Published in Emerging Trends in Metabolites · Vol. 1, Issue 1, 2024 · pp. 7–26 Read article
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Chemiluminescence: Recent Developments and Photochemical Applications in Analytical Chemistry
Abstract: Chemiluminescence (CL) is the observable production of electromagnetic radiation from a chemical reaction, typically in the form of ultraviolet, visible, or infrared light. According to subjective yield, CL has either been directly emitted from electronically excited intermediate products, or it has been supported by another molecule to emit CL. Since the 1950s, CL has been supported as a valid analytical tool, with the descriptive issued scope being limited to content …
Published in International Journal of Photochemistry and Photochemical Research · Vol. 2, Issue 1, 2024 · pp. 20–25 Read article
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QSAR Modeling Techniques: A Comprehensive Review of Tools and Best Practices
Abstract: Quantitative Structure–Activity Relationship (QSAR) modeling has become an essential tool in drug discovery, toxicity assessment, and environmental chemistry. By correlating chemical structure with biological activity or toxicity, QSAR enables the prediction of compound behavior without extensive experimental testing. This approach not only saves time and resources but also supports ethical practices by reducing reliance on animal studies. The evolution of QSAR from basic linear models to advanced machine learning and …
Published in International Journal of Cheminformatics · Vol. 3, Issue 1, 2025 · pp. 56–63 Read article
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Exploring the Therapeutic Potential of Grapeseed Phytoconstituent Through Molecular Docking Analysis for Multiple System Atrophy Treatment
Abstract: Objective: Alpha-synuclein (α-Syn) aggregates are a common neurodegenerative disorder associated with Parkinson’s disease and multiple system atrophy (MSA). As a fruit that is extensively grown, grapes have several pharmacological advantages when it comes to reducing oxidative stress. Research has indicated that grape seed phytoconstituents have a major effect on α-Syn. The objective of this study is to inquire into the pharmacological characteristics and potential therapeutic applications of grape seed derivatives …
Published in International Journal of Molecular Biotechnological Research · Vol. 2, Issue 2, 2024 · pp. 14–26 Read article
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Improving Dataset Integrity Through Automated Data Cleaning Techniques
Abstract: High-quality data is a fundamental requirement in data science for producing trustworthy analytical insights and effective machine learning models. Problems, including incomplete records, inconsistent entries, duplicate observations, and anomalous values, can severely reduce the accuracy and robustness of predictive systems. As modern datasets continue to expand in both volume and structural complexity, relying on manual data cleaning methods become time-consuming and error-prone, highlighting the growing importance of automated data preprocessing …
Published in International Journal of Data Structure Studies · Vol. 4, Issue 1, 2026 · pp. 40–45 Read article
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Impact of Fracture in Geometrical, Material, and Load Rate Characteristics on J-Integral
Abstract: The present study investigates the influence of load rate, geometrical parameters, and material properties on the J-integral behavior of AA2050-T84 aluminum-lithium alloy using three-dimensional elastic–plastic fracture mechanics (EPFM) analysis. Finite element simulations were carried out using the ABAQUS software to evaluate crack driving forces in compact tension (C(T)) specimens under various mechanical and thermal conditions. The study focuses on the combined effects of strain rate, temperature-dependent strain hardening, specimen thickness …
Published in International Journal of Fracture Mechanics and Damage Science · Vol. 4, Issue 1, 2026 · pp. 38–45 Read article
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Identification of Promising Lead Compounds from Capsicum annuum Targeting BACE-1 for Alzheimer’s Disease Therapy: A Molecular Docking Study
Abstract: Background: Alzheimer's disease (AD) is a neurodegenerative disorder affecting millions of people worldwide. Beta-secretase 1 (BACE-1) is an important therapeutic target for AD treatment. Capsicum annuum (CA) is a commonly consumed plant with potential neuroprotective properties. In this study, we aimed to identify potential lead compounds from CA that can target BACE-1 for AD therapy using molecular docking. Methods: A library of 15 compounds from CA was obtained from PubChem, …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 1, Issue 1, 2023 · pp. 40–49 Read article
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Fracture Analysis of FRP Composites under Thermo-Mechanical Loads for Different Geometry Cutouts
Abstract: Fiber-reinforced composites (FRPs) are used extensively in structural and non-structural components of the aerospace and automotive industries. To utilize these materials for structural applications, it is necessary to understand the fracture behavior of the material. In the present investigation of carbon fiber laminates, studies were carried out to understand the fracture toughness characteristics of the carbon fiber laminates with mechanical, thermal, and thermo-mechanical loadings of modes I, II, and III. …
Published in International Journal of Fracture Mechanics and Damage Science · Vol. 3, Issue 2, 2025 · pp. 1–10 Read article
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Floating Cities from Concept to Creation :Neighbourhood Guide to the Future Development
Abstract: Today cities are overpopulated and only 40% of space is left to house the world's population by 2050. Due to ever rising sea level 90% of coastal cities will be affected by flooding by the end of the century. This research aims to study about the floating city as a substitute. Floating cities shape to construct all of the infrastructure required for a water-based metropolis while also providing contextual space …
Published in International Journal of Urban Design and Development Read article
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Predicting Student Placement Readiness: A Machine Learning Approach Using Coding Activities and Multi-Dimensional Performance Indicators
Abstract: In the modern information-driven academic world, identifying student employability and placement preparedness has predicted. be made a part and parcel of academic planning and career. development. This study provides a machine learning-based. structure to evaluate and forecast student placement pre-paredness by combining various performance aspects-academic achieve- ment, coding activity, aptitude and behavioral engage-ment metrics. Multi-source was gathered and preprocessed in the study. student information, such as student records (CGPA, attendance), …
Published in International Journal of Education Sciences · Vol. 3, Issue 2, 2026 Read article
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Electromagnetic Propulsion Train for Future Transportation
Abstract: The Electromagnetic Propulsion Train project focuses on the development and analysis of a prototype system that achieves linear motion through the application of controlled electromagnetic forces. Unlike conventional railway systems that rely primarily on mechanical drive mechanisms such as wheels, axles, and traction motors, this project explores an alternative propulsion approach based on electromagnetic interaction. In this system, a sequence of electromagnets is strategically positioned along the track to generate …
Published in International Journal of Electro-Mechanics and Material Behaviour · Vol. 3, Issue 2, 2025 · pp. 25–31 Read article
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Effectiveness of Sensitization Program on Knowledge of School Children Regarding Refractive Errors
Abstract: The human eyes are portals of absorbing divine knowledge from the surrounding world. These two precious pearls need to take proper care throughout to taste life. The eye care starts right from birth onward and becomes keenly required in children's school age as they use these gifts for intense learning. The neglected care in the initial years may trouble them with various visual disorders and disturb their studies too. Well-structured …
Published in Recent Trends in Infectious Diseases · Vol. 1, Issue 1, 2024 · pp. 13–20 Read article
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Effect of Mindfulness-Based Yoga Practices on Anxiety and Attention Level Among High School Children in a Selected High School, Bhubaneswar, Odisha
Abstract: Background: In a world filled with endless pressures and expectation, school-aged children often find themselves navigating through a labyrinth of stressors and anxiety. from the moment they wake up their tiny minds are bombarded with worries about exams, social interaction.it is in these moments of chose that the ancient practice of yoga emerges as a gentle beacon of hope, offering solace and tranquility to these young souls. The study main …
Published in International Journal of Evidence Based Nursing And Practices · Vol. 1, Issue 2, 2023 · pp. 1–8 Read article
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Effectiveness of A structured teaching program on Leucorrhoea and it's management for women of Reproductive age group at selected college in Honavar
Abstract: Leucorrhea, also known as leucorrhea, is a white, yellow, or green discharge from a woman's vagina, which may be normal or asign of an infection. Leucorrhea is common during pregnancy and is typically normal if the discharge is thin, white, and odorless.Physiological leucorrhea is a condition that occurs in young women several months to a year after the onset of menstruation. It sometimes occurs in newborn girls and usually lasts …
Published in International Journal of Women's Health Nursing And Practices · Vol. 2, Issue 2, 2024 · pp. 40–44 Read article
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To Propose an Effective Process for Refurbishment Projects: through BIM
Abstract: Building refurbishments include enhancing, upgrading, renovating, retrofitting, and repairing existing structures. The construction sector considers it to be an important component. Building refurbishment projects are known for their high degree of complexity and uncertainty, which frequently incorporates elements like design changes and inadequate or unavailable information that may lead to various issues. Issues related to different stages of refurbishment projects were identified through literature and case studies. According to the …
Published in International Journal of Architectural Design and Planning Read article