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49 articles for “small molecules”
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An Overview of Fanconi Anemia: A Genetic Disorder
Abstract: Fanconi Anemia (FA) is a rare genetic disorder caused by DNA repair defects due to pathogenic variants in one of 21 genes. It is the primary cause of inherited bone marrow failure, marked by pancytopenia. Clinically, Fanconi Anemia (FA) is associated with congenital malformations in multiple systems, resulting in progressive bone marrow failure and heightened cancer risk, especially in the urogenital region and the head and neck. There are approximately …
Published in International Journal of Oncological Nursing and Practices · Vol. 2, Issue 2, 2024 · pp. 19–25 Read article
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Evaluation of Anti-cataract Potential of Carbocisteine by Using In Vitro Goat Lens Model
Abstract: This study includes Carbocisteine has four Oxygen molecules, one Sulfur molecule, and one Nitrogen molecule. Goat eyeballs were used in the present study. They were obtained from the slaughterhouse. Glucose at a concentration of 55 mM was used to induce cataracts; glucose (5.5 mM) concentration served as a normal control, and Ascorbic Acid served as a standard control. Incubation of lenses with glucose 55 mM showed opacification starting after 8 …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 16, Issue 2, 2026 Read article
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Malaria Diagnosis through Conventional Methods: A Comprehensive Review
Abstract: The incidence of drug-resistant parasite strains is rising, there is an apparent increase in the number of cases of malaria worldwide, and in a small number of cases and there has been a dramatic rise in international migration and travel. Over 1 million people die from malaria every year; 90% of these deaths are in African children, who live in tropical and subtropical regions. Although there are now efficient techniques …
Published in International Journal of Pathogens · Vol. 1, Issue 2, 2024 · pp. 8–14 Read article
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Machine Learning for Finding Materials for Membranes
Abstract: Traditionally, finding and improving membrane materials has depended on trial-and-error experiments, which can take a long time, cost a lot of money, and only cover a small area. Recent improvements in machine learning (ML) have the potential to change the way membrane materials are designed by making it possible to make predictions about performance, selectivity, and stability based on data. ML algorithms can find hidden links between the structure, composition, …
Published in International Journal of Membranes · Vol. 3, Issue 1, 2026 · pp. 1–7 Read article
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Examining the Medicinal Role of Alum in Unani Medicine: An Overview of Traditional Uses and Scientific Investigations
Abstract: Alum, also known as Shibb-e-Yamani, is a crystalline substance devoid of color, transparent, and lacking any scent. It possesses a sweetish astringent flavor and is categorized as a hydrated double salt. Typically, it comprises aluminum sulfate, water molecules as part of its structure, and the sulfate of another element. Frequently, it's found mixed with impurities. To render it suitable for medicinal usage, a process involves dissolving it in boiling water, …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 13, Issue 1, 2024 · pp. 1–9 Read article
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Energy Time Scale Theory
Abstract: Time is the scale for the measurement of the various activities happening in the whole universe. Therefore, it also can be commented that, "Time is the scale for the measurement of the rate of the change of the energy from one form to another into its various states. That means the range of the various states of the energy starts from string and waves and reaches up to quantum particles, …
Published in International Journal of Universe · Vol. 1, Issue 2, 2025 · pp. 01–07 Read article
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Bioconjugates and Biohybrid Polymers: Intricate Cellular Integration Methods and Sophisticated Biofunctionalization Techniques for Tailored Properties in Medical Contexts
Abstract: Bioconjugates are made when biological molecules are covalently linked to manufactured polymers. They can be used in many ways for imaging, diagnosis, and specific drug delivery. Getting perfect cellular fusion is very important for how well they work. Biomolecules can be attached to polymer scaffolds in a controlled way using techniques like click chemistry and site-specific conjugation. This makes sure that the molecules connect optimally with their biological targets. Using …
Published in Journal of Polymer & Composites · Vol. 12, Issue 3, 2024 · pp. 227–243 Read article
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Practical studies in Vero cell and Human amnion cells for viral and stem cell applications
Abstract: Vero cells are one of the most popular mammalian continuous cells in molecular, cellular, and microbiological research. African green monkey kidneys are used to make these.One continuous cell line is the Vero cell line. This cell line is dependent on anchorage. Vero cells can be cultured in suspension because they are anchorage independent. Thought to be non-tumorigenic cells that came from a female Chlorocebus sabaeus Numerous viruses can infect vero …
Published in International Journal of Vaccines · Vol. 2, Issue 1, 2025 · pp. 1–8 Read article
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Pharmacophore mapping, 3D QSAR, docking, and ADME prediction studies of novel Benzothiazinone derivatives
Abstract: Background Tuberculosis is a major public health concern worldwide which is caused by Mycobacterium tuberculosis. DprE1 (Decaprenyl Phosphoryl Ribose 2’- Epimerase) is the most challenging target for development of novel anti- tubercular agents because it is a small protein and located into cytoplasmic membrane. So, novel anti-TB drugs did not bound effectively with it. DprE1 catalyzes the oxidation of the 2’ hydroxyl group of DPR (Decaprenyl Phosphoryl D- Ribose) …
Published in International Journal of Antibiotics · Vol. 1, Issue 1, 2024 · pp. 59–82 Read article