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76 articles for “mucositis”
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Mandible reconstruction following resection of gingival squamous cell carcinoma with peroneal artery perforator based fibular osteocutaneous free flap
Abstract: Reconstructing soft tissue defect resulting from resection of malignant tumor in face is crucial in esthetic and functional point of view. To address this condition, various surgical flaps are used, including the free vascularized osteocutaneous flap. In this case, we used a free fibular osteocutaneous flap to reconstruct both the bone (osseous) and soft tissue (mucosal) defects. These defects were caused by the removal (resection) of a lesion in a …
Published in Research and Reviews: A Journal of Dentistry · Vol. 16, Issue 2, 2025 · pp. 12–18 Read article
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Role of Nasya in Pakshaghata: An Evidence-Based Review Study on Its Anatomical Pathway and Therapeutic Action
Abstract: Introduction: Intranasal administration (Nasya), a time-honoured Ayurvedic procedure, offers a unique advantage in treating pathology of neurological and systemic diseases due to its targeted and non-invasive nature. Pakshaghata, a neurological disorder characterized by hemiplegia in ancient Ayurvedic literature, where it is classified as a Vatavyadhi. Methods: By going through all the available literatures and information, this review study explores the concept of Nasya in the context of Pakshaghata management, investigating …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 14, Issue 2, 2025 · pp. 1–8 Read article
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Carboxymethyl Cellulose-Based Spray-Dried Microspheres: Recent Advances and Applications in Targeted Drug Delivery Systems
Abstract: Microspheres are spherical particles ranging from 1 to 1000 μm, made from natural or synthetic polymers and inorganic materials. Their structure allows precise drug delivery, improving targeted release and minimizing off-target effects. Natural polymers such as starch, chitosan, and alginate are favored for their biodegradability, adhesion, and compatibility, enhancing mucosal interaction and residence time. Microspheres are widely used in site-specific drug delivery, gene therapy, and vaccine administration, improving immunogenicity, extending …
Published in Journal of Polymer & Composites · Vol. 13, Issue 5, 2025 · pp. 251–268 Read article
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Synthesis of Silver Nanoparticles of Cissus Quandrangularis and It’s Virtual Screening Against Gastric Cancer
Abstract: Gastric cancer, also known as stomach cancer, is the third leading cause of cancer-related deaths globally and remains a major health challenge due to its poor prognosis and high mortality, largely attributed to late-stage diagnosis. In this context, plant-based nanomaterials are gaining momentum for targeted therapeutic applications. Cissus quadrangularis, a medicinal plant native to India from the Vitaceae family, is traditionally used for its diverse healing properties. Its stem, in …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 1551–1569 Read article
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Exploring the Therapeutic Potential of Phytochemicals in Aloe Barbadensis Miller Through Molecular Docking for Ulcerative Colitis Management
Abstract: Ulcerative colitis (UC) is a chronic inflammatory bowel disease characterized by mucosal inflammation of the colon, often associated with immune dysregulation and oxidative stress. Natural compounds have gained significant attention as alternative therapeutic agents due to their efficacy and minimal side effects. Quercetin, a flavonoid abundantly found in Allium cepa (onion), has demonstrated potent anti-inflammatory and antioxidant properties. This study employs an in silico approach to evaluate the therapeutic potential …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 13, Issue 1, 2026 · pp. 06–12 Read article
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Nutrition Induced Gut Microbiota Modulation in Food Animals: Implications for Viral Susceptibility, Shedding and Transmission Dynamics for Sustainable Development
Abstract: The gut microbiota has emerged as a central mediator linking host nutrition, immune competence, and vulnerability to viral pathogens in food animals. Diet is a primary driver of microbial community structure and function, influencing metabolite production, intestinal barrier integrity, and systemic antiviral immunity. Accumulating evidence indicates that nutrition induced modulation of the gut microbiota can substantially alter viral susceptibility, replication, and shedding patterns, with downstream effects on transmission dynamics within …
Published in International Journal of Virus Studies · Vol. 3, Issue 1, 2026 · pp. 46–56 Read article
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Dental and Oral Health Challenges in Patients with Eating Disorders: An Updated Review
Abstract: Eating disorders are complicated psychiatric disorders with profound systemic and oral health implications that are often not identified in clinical practice. Dietary restriction, binge eating, and self-induced vomiting are disorders eating behavior that negatively impact the oral cavity via nutritional deficiency, exposure to acid, malfunction of salivary activities, and changes in immune and microbial. These processes lead to a wide spectrum of oral and dental effects such as dental erosion, …
Published in Research and Reviews: A Journal of Dentistry · Vol. 17, Issue 1, 2026 · pp. 25–34 Read article
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Gut Microbial Metabolites in Inflammatory, Metabolic, and Neurologic Disorders.
Abstract: The human gut microbiota transforms dietary and hostderived substrates into a diverse array of metabolites—including shortchain fatty acids (SCFAs), hydrogen sulfide (H₂S), bile acid derivatives, indoles, trimethylamine Noxide (TMAO), branchedchain amino acid (BCAA) derivatives, and lipopolysaccharide (LPS)—that act as key signaling mediators along epithelial, immune, endocrine, and neural axes. These metabolites regulate barrier integrity, energy homeostasis, inflammation, and gut–brain communication and are increasingly implicated in the pathogenesis of inflammatory bowel …
Published in Emerging Trends in Metabolites · Vol. 3, Issue 1, 2026 · pp. 58–64 Read article
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A Comprehensive Review on the Role of Antacids in the Management of Stomach Disorders
Abstract: Antacids are among the most widely used over-the-counter medications for the symptomatic management of acid-related gastrointestinal disorders, including dyspepsia, gastroesophageal reflux disease (GERD), gastritis, and peptic ulcer disease. These agents provide rapid relief by neutralizing gastric hydrochloric acid, thereby increasing intragastric pH and reducing mucosal irritation. In addition to their therapeutic benefits, the long-term and excessive use of antacids may be associated with adverse effects and toxicological concerns, including electrolyte …
Published in International Journal of Toxins and Toxics · Vol. 3, Issue 2, 2026 Read article
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Gastro Retentive Drug Target System: Its Needs, Advantages, Limitation and Approaches
Abstract: Background: Gastro retentive drug delivery systems (GRDDS) address limitations of oral therapy for drugs with poor solubility, instability at intestinal pH, or narrow absorption windows by prolonging gastric residence and increasing contact with the gastric mucosa. Objectives: To review GRDDS approaches—floating systems, mucoadhesive systems, and super porous hydrogels—with emphasis on formulation strategies and polymer–excipient selection to enhance gastric retention, modulate buoyancy/swelling/adhesion, and ultimately improve oral bioavailability and therapeutic outcomes for …
Published in Trends in Drug Delivery · Vol. 13, Issue 2, 2026 · pp. 47–58 Read article
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A Clinical Case Study of Kaphaja Visarpa W.S.R to Pemphigus Vulgaris
Abstract: Background: Visarpa is a classical Ayurvedic dermatological condition characterised by Swift spreading of lesions across the skin involving Twak, Lasika, Rakta, and Mamsa. Kaphaja Visarpa, a subtype dominated by Kapha dosha, presents with pallor-coloured oily lesions, itching, swelling, and mild pain. Case Summary: A 58-year-old female patient, a known case of Type 2 Diabetes Mellitus, presented with shiny, oedematous, pale skin lesions across the chest, abdomen, and back, accompanied by …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 15, Issue 2, 2026 Read article
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Concept of Rhinosinusitis in the Unani Medicine: A Systematic Review
Abstract: Chronic rhinosinusitis (CRS) is a common multifactorial inflammatory disease of the mucosal lining of nose and paranasal sinuses. It is a frequently occurring disease, with significant impact on quality of life and health care spending, and economic impact in terms of absenteeism and productivity. The signs and symptoms of Warm-e-Tajaweef Anaf Muzmin (Chronic rhinosinusitis) are consistent with Nazla barid which depend on the involvement of paranasal sinuses. About 5–15% of …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 6, Issue 3, 2017 · pp. 33–41 Read article
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Homoeopathic Management of Irritable Bowel Syndrome: A Case Study
Abstract: Irritable Bowel Syndrome (IBS) is a functional GI disorder characterized by abdominal pain and altered bowel habits. It is the most common reason for referral to gastroenterologists. The global mean prevalence of IBS ranges from 1.1% in France and Iran to 35.5% in Mexico. Patients often experience the onset of symptoms as young adults and most patients have their first symptoms before the age of 35. IBS has both physiological …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 7, Issue 3, 2018 · pp. 16–20 Read article
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A Case Study on the Ayurvedic Management of Ulcerative Colitis (Grahani)
Abstract: Ulcerative Colitis is an idiopathic form of acute and chronic ulcero-inflammmatory colitis affecting chiefly the mucosa and submucosa of the rectum and descending colon, though sometimes it may involve the entire large intestine. Symptoms usually develop over time, rather than suddenly. Ulcerative colitis can be debilitating and can sometimes lead to life-threatening complications. While it has no known cure, treatment can greatly reduce signs and symptoms of the disease and …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 10, Issue 1, 2021 · pp. 41–45 Read article
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Important Product Used As Cosmetic in Unani Medicine
Abstract: Any single substance or compound product intended for local application of external parts of human body or teeth and mucosal membrane of oral cavity called as cosmetics. The cosmetics are exclusively or mainly used to cleaning, perfuming, beautifying, adorning, changing the personality and appearance, being attracting, etc. The knowledge of these natural cosmetic products was successfully compiled in Unani medicine specially in in Kitab al mansoori & 23rd volume of …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 5, Issue 1, 2016 · pp. 44–47 Read article
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Alveolar Cysts in a Newborn Infant: A Case Report
Abstract: Cystic lesions of transient nature through Epstein pearls, Bohn’s nodules and dental lamina cysts are frequently found in the oral cavities of newborn infants. These cysts arise from the developing dental tissues or from their remnants. Alveolar cyst is also known as gingival cyst of newborn or dental lamina cyst. This cyst presents as a benign oral lesion which is whitish-yellow in color present on the alveolar ridge of newborns …
Published in Research and Reviews: A Journal of Dentistry · Vol. 8, Issue 3, 2017 · pp. 26–28 Read article
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Phentolamine Mesylate: An Antidote for Local Anesthesia; A Boon in Dentistry
Abstract: The most frequently administered drugs in dentistry are local anesthetics. Local anesthetics also represent the safest and the most effective drugs available in medicine for both the control and prevention of pain occurring during and following invasive procedures. These not only provide relief from pain during procedures but also leave an inconvenient residual numbness that takes some time to wear off following completion of dental procedures. OraVerse, an injectable formulation …
Published in Research and Reviews: A Journal of Dentistry · Vol. 5, Issue 1, 2014 · pp. 11–14 Read article
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Granuloma Pediculatum Benignum: A Case Report and Review of Literature
Abstract: Pyogenic granuloma or granuloma pyogenicum represents about 57% of benign non-neoplastic oral lesions. Pyogenic granuloma of the oral cavity is known to most commonly involve gingiva. Extragingivally, it can occur on the lips, tongue, buccal mucosa and palate. The etiology of the lesion is not known, though it was originally believed to be a botryomycotic infection. It is theorized that pyogenic granuloma possibly originates as a response of tissues to …
Published in Research and Reviews: A Journal of Dentistry · Vol. 4, Issue 1, 2013 · pp. 1–4 Read article
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Sublingual Dermoid Cyst: Case Report
Abstract: Dermoid cysts are rare masses of the oral cavity derived from ectodermal elements. In the present case, the lesion in the floor of the mouth showed soft consistency, floating, regular borders, smooth surface, and the same color as the adjacent mucosa, asymptomatic and measuring 4×4 cm in its greatest diameter, the mass was completely excised through an intraoral approach, the histological features were suggestive of dermoid cyst, the patient did …
Published in Research and Reviews: A Journal of Dentistry · Vol. 11, Issue 1, 2020 · pp. 24–28 Read article
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Effect of Sodium Fluoride and Cellulose Gum Toothpaste over Regular SLA Toothpaste in Reducing Xerostomia-A Retrospective Cohort Study
Abstract: Our aim is to study the effect of mildly flavoured sodium fluoride 0.2% and cellulose gum on patient suffering from chronic xerostomia in comparison to effect of general sodium Laurel sulphate containing toothpaste on same condition patient. A controlled study population was used for the investigation. The baseline for this study is to estimate the risk of developing xerostomia or worsening of the condition in patient already suffering from xerostomia …
Published in Research and Reviews: A Journal of Dentistry · Vol. 13, Issue 2, 2022 · pp. 22–24 Read article