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58 articles for “computational screening”
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Study of Lipid Profile and Its Correlation with Coronary Angiogram Finding in a Tertiary Care Hospital in an Urban Setting
Abstract: Coronary artery disease (CAD) is a major global health concern caused by the constriction or blockage of the coronary arteries, which can result in serious cardiovascular events. This study looks at the relationship between lipid profiles and the severity of CAD as measured by coronary angiography in patients in a tertiary care hospital. The study focuses on dyslipidemia as a major risk factor for CAD, emphasizing the importance of efficient …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 14, Issue 3, 2024 · pp. 106–118 Read article
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Illuminating the Frontier of Drug Discovery: Unleashing the Power of Bioinformatics for Unprecedented Breakthroughs
Abstract: It takes a long time and a lot of effort to discover and develop new drugs, which necessitates extensive study and testing. With the help of computational techniques and data analysis, bioinformatics has grown to be a potent tool for drug discovery in recent years, allowing researchers to find new drugs faster. In this review, we examine the role of bioinformatics in drug discovery, including the use of ligand- and …
Published in International Journal of Molecular Biotechnological Research · Vol. 1, Issue 2, 2023 · pp. 1–10 Read article
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CNN-Based Diagnosis of Skin Cancer from Dermoscopic Images
Abstract: Skin cancer has become one of the diseases widely spread over the globe, with melanoma becoming a severe threat to one’s health. Detection of such diseases at the initial stage saves an individual from drastic damage. Using a Convolutional Neural Network (CNN) for detecting skin cancer through image classification as benign or malignant provides significant support to dermatological practice and reduces dependence solely on subjective visual examination. Dermatologists often face …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 15, Issue 1, 2026 · pp. 37–42 Read article
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The Contribution of A. I. in Pharmaceutical Software
Abstract: The integration of Artificial Intelligence (AI) in pharmaceutical software has significantly transformed drug development, regulatory processes, and clinical management. AI-powered tools are revolutionizing data analysis, predictive modeling, and decision-making, enhancing the efficiency and accuracy of drug discovery and development. This article explores the multifaceted contributions of AI to pharmaceutical software, including its applications in drug screening, personalized medicine, clinical trial optimization, and regulatory compliance. Additionally, we examine how AI is …
Published in International Journal of Biomedical Innovations and Engineering · Vol. 3, Issue 1, 2025 · pp. 1–10 Read article
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Virtual Clothes Try-On
Abstract: Virtual try-on of clothes is gaining popularity thanks to its commercial potential. It can be used for intelligent recommendation or online purchasing to reduce the selection to a few designs and sizes. Through this project we aim to create a mechanism that enables users to see themselves wearing virtual clothes while looking at a screen display, without taking off their actual clothes. We aim to stimulate the selected clothes on …
Published in International Journal of Algorithms Design and Analysis Review · Vol. 1, Issue 1, 2023 · pp. 16–20 Read article
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In Situ Investigation of Hemidesmus indicus Phytocompound Extracts as a Therapeutic Target for Acute Myeloid Leukemia
Abstract: Objective: Acute myeloid leukemia (AML) is an apoptotic condition in the hematopoietic system induced by the differentiation and maturation of stem cells into erythrocytes, and leukemic cell proliferation is suppressed as the PI3K-Akt-mTOR pathway is pharmacologically targeted with certain inhibitors. As a result, in silico molecular docking of compounds against AML receptors, CTMP, was used in computational research on Hemidesmus indicus to uncover therapeutic phytochemicals for AML. Thus, this study …
Published in Research and Reviews : Journal of Computational Biology · Vol. 13, Issue 1, 2024 · pp. 38–53 Read article
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Intrusion Eye Detector
Abstract: Uncertainty about security risks and illegal access are becoming more prevalent in a variety of settings, such as private homes, business buildings, and critical government buildings. Conventional security systems, which may not offer real-time warnings or prompt reactions, frequently rely on passive monitoring, including CCTV cameras and motion sensors. Artificial intelligence (AI) and computer vision-based intelligent systems are becoming more and more popular as a means of improving security and …
Published in International Journal of Optical Innovations & Research · Vol. 3, Issue 1, 2025 · pp. 28–32 Read article
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Precision Medicine for Neurofibromatosis Type 1: Progress and Prospects in Drug Discovery
Abstract: Objective: The development of neurofibromas, café-au-lait spots, and other neurological problems are the hallmarks of neurofibromatosis type 1 (NF1), a hereditary disorder. The dearth of efficacious pharmaceutical therapies underscores the need for novel therapeutic approaches, even in the face of clinical variability. Through very accurate prediction of the binding affinity of possible therapeutic drugs with the target protein, the computational technique known as “molecular docking” has become a potent tool …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 2, Issue 1, 2024 · pp. 01–15 Read article
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Role of Fluid Engineering in Biomedical and Healthcare Systems: A Comprehensive Review
Abstract: Fluid engineering — the study and application of fluid behavior, transport, and interaction — has become a cornerstone of modern biomedical and healthcare systems. This review synthesizes the multifaceted roles fluid engineering plays across diagnostics, therapeutics, biomedical devices, and physiological modeling. Micro-fluidics enables precise manipulation of microliter and nanoliter volumes, facilitating rapid point-of-care diagnostics, high-throughput screening, and the fabrication of uniform nano particles for targeted drug delivery. In cardiovascular medicine, …
Published in Trends in Mechanical Engineering & Technology · Vol. 16, Issue 1, 2026 · pp. 1–5 Read article
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SkinSight: Design and Implementation of an Intelligent Skin Type Detection System
Abstract: Identifying an individual’s skin type accurately is essential for creating personalized dermatological treatments and formulating skincare products that genuinely meet user needs. In this project, a real- time skin type classification system is developed using a combination of convolutional neural networks (CNNs) and modern computer vision techniques. The system processes live video streams, isolates the facial region through Haar cascade–based detection, and applies a series of preprocessing steps to enhance …
Published in Journal of Image Processing & Pattern Recognition Progress · Vol. 13, Issue 1, 2026 · pp. 35–45 Read article
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IoT in Water Resource Management: Trends and Innovations in Water Level Monitoring Systems
Abstract: One of the major problems faced by most of the countries in the world is the issue of water scarcity, and wastage during transmission has been identified as a major culprit; this is one of the motivations for this research, to deploy computing technician creating a barrier to wastage in order to not only provide more financial gains and help the environment as well as the water cycle which in …
Published in Journal of Microcontroller Engineering and Applications · Vol. 12, Issue 1, 2025 · pp. 39–45 Read article
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Multitarget Molecular Docking Using Curcuma longa Phytocompounds for Polycystic Ovary Syndrome Treatment
Abstract: Objective: The primary goal of this research is to understand and describe specific aspects of molecular interaction, it includes studying various aspects such as binding affinity, binding mode, and stability of the ligand-protein complex. Molecular docking is a computational technique used to predict the preferred orientation of one molecule to a second when bound together to form a stable complex. In this study, molecular docking will be employed to stimulate …
Published in International Journal of Molecular Biotechnological Research · Vol. 2, Issue 1, 2024 · pp. 15–28 Read article
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DFT/Data Guided Predictive Modelling of Absorption Maxima in the OLED Rubrene Derivatives
Abstract: This study investigates the optical properties of rubrene derivatives to develop an accurate predictive model for absorption maxima using computational chemistry and chemoinformatic techniques. We benchmarked various quantum chemical methods, identifying that the M06-2X/aug-cc-pVDZ method in dichloromethane (DCM) provided the strongest correlation with experimental data. Key molecular descriptors such as band gap, ionization potential, and electrophilicity index were calculated and analyzed using principal component analysis (PCA) to identify significant factors …
Published in International Journal of Cheminformatics · Vol. 4, Issue 1, 2026 · pp. 41–56 Read article
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A Comparative Study of Transfer Learning-Based Deep Learning Models for Breast Cancer Detection
Abstract: Breast cancer is a major concern in the world today, and early and accurate diagnosis is most crucial in the case of breast cancer, as it is among the disorders where the total cost of loss of life is high. Traditional screening processes are subjective and vulnerable to inter-observer reliability issues and diagnostic errors, being primarily based on manual interpretation of medical images. To address these limitations, Deep Learning (DL) …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 15, Issue 1, 2026 · pp. 24–34 Read article
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Prediction of Mechanical Properties for Advanced Engineering Applications utilizing Polymer Composite Materials by Machine Learning
Abstract: Polymer composites show great promise as engineering materials because of their mechanical performance, resistance to corrosion, lightweight nature, and adaptability in design. Aerospace, automotive, biomedical, maritime, and civil engineers all rely on mechanical property prediction to cut down on trial expenses, expedite product development, and optimize material selection. Speedy design optimization is not possible using traditional numerical and experimental methods due to the high costs associated with material characterisation, computational …
Published in Journal of Polymer & Composites · Vol. 14, Issue 3, 2026 Read article
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Smart Iron Box with Automatic Cloth Detection and Heat Adjustment
Abstract: Ironing continues to be a lengthy and sometimes monotonous activity in domestic chores; especially among those with busy schedules who need to ensure efficiency and minimize risks of harming delicate fabrics. This document discusses the design and development of an intelligent ironing machine that performs ironing tasks using embedded computing and multi-sensor fabric identification. Unlike traditional irons that depend entirely on the manually chosen temperatures and user discretion, the developed …
Published in International Journal of Electrical and Communication Engineering Technology · Vol. 4, Issue 2, 2026 Read article
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Predicting Dielectric Constants of Polymers Using Molecular Structural Descriptors and Explainable Machine Learning: A Data-Driven Approach
Abstract: Accurate prediction of dielectric constants in polymeric materials is fundamental to the rational design of advanced electronic components, energy storage capacitors, flexible substrates, and high-frequency communication circuits. Conventional approaches to identifying suitable polymer dielectrics rely on extensive experimental synthesis and characterisation, which are both time-consuming and resource-intensive. In this work, an explainable machine learning framework is developed to predict the dielectric constant of polymers directly from molecular structural descriptors derived …
Published in Journal of Polymer & Composites · Vol. 14, Issue 3, 2026 · pp. 297–304 Read article
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Transforming Rare Disease Diagnosis with AI
Abstract: Artificial intelligence is changing healthcare fast. It is making diagnoses accurate, helping doctors get better results, and streamlining how care works. This paper looks at how AI shows up in healthcare right now – where it is already making a difference, what is working, and what is still tricky. The focus is on machine learning, natural language processing, and computer vision. Particular attention is given to using AI in diagnosing …
Published in Research and Reviews : Journal of Computational Biology · Vol. 15, Issue 1, 2026 Read article