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485 articles for “Mechanism” (ranking capped at the first 2,000 matches — narrow the search to see the rest)
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Postbiotics Unveiled: Mechanistic Insights and Therapeutic Implications in Obesity.
Abstract: The burgeoning global obesity epidemic necessitates innovative therapeutic approaches, and postbiotics, bioactive compounds arising from microbial fermentation, have emerged as promising contenders in reshaping obesity management. This comprehensive review explores the multifaceted mechanisms by which postbiotics impact obesity, from modulating gut microbiota composition to influencing metabolic pathways and enhancing energy expenditure. The exploration of postbiotics is rooted in a deeper understanding of the gut–brain axis and bidirectional communication between gut …
Published in Emerging Trends in Metabolites · Vol. 3, Issue 1, 2026 · pp. 11–28 Read article
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A study on Antibiotic Resistance: An Analysis of Molecular Mechanisms and Therapeutic Implications
Abstract: Antibiotic resistance (AR) represents one of the most critical existential threats to global public health, rapidly eroding the efficacy of established antimicrobial therapies and portending a return to the pre-antibiotic era. This analysis explores the intricate molecular landscape defining this crisis, focusing specifically on the primary mechanisms of action (MoA) utilized by major antibiotic classes—including cell wall inhibitors, protein synthesis inhibitors, and nucleic acid synthesis inhibitors—and the corresponding, diverse mechanisms …
Published in International Journal of Antibiotics · Vol. 3, Issue 1, 2026 · pp. 9–21 Read article
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Effect of Nanoclay Loading on Physical and Mechanical Properties of Epoxy Composites
Abstract: The effects of multilayer silicate loading on hardness, tensile, and impact properties were examined by developing epoxy–nanoclay composites with 0–5 wt% nanoclay. A desirable compromise between reduced void content and higher Shore D hardness was reached with an ideal nanoclay loading of 3 wt%, which reflected improved load transfer and increased matrix stiffness as a result of limited polymer chain mobility. Tensile strength and modulus rose up to 3 wt% …
Published in International Journal of Advance in Molecular Engineering · Vol. 4, Issue 1, 2026 · pp. 36–45 Read article
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Functional Biomolecules in Animal Nutrition: Biochemical Mechanisms and Their Impacts on Growth Performance and Health Outcomes
Abstract: Functional biomolecules have emerged as critical modulators of animal nutrition, extending beyond conventional nutrient supply to regulate biochemical and physiological processes that determine growth performance and health outcomes. This review synthesizes current knowledge on diverse classes of bioactive compounds, including amino acids, peptides, fatty acids, vitamins, minerals, phytochemicals, and microbial-derived metabolites, and their roles in livestock systems. Emphasis is placed on underlying biochemical mechanisms such as enzyme activation, nutrient signaling …
Published in International Journal of Nutritions · Vol. 3, Issue 2, 2026 Read article
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Exploring The Multitarget Pharmacological Mechanism of Diabex for T2dm by Combining Network Pharmacology and Molecular Docking Techniques
Abstract: Objective: Hyperglycemia brought on by an absolute or relative absence of insulin synthesis or action characterises a set of illnesses known as diabetes mellitus. Chronic hyperglycemia in diabetes mellitus has been linked to organ damage, heart, and blood vessels. The persistent metabolic condition Diabetes is a severe global issue with negative social, health, and economic effects. It is a type of metabolism disorder that interferes with food digestion in the …
Published in International Journal of Bioinformatics and Computational Biology Read article
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Modeling of the Mechanism of Generating Processes of Water Electrolysis and Photosynthesis with Solar Energy Used for Productions of Gas Oxygen and Hydrogen, of Concentrate of the High-calorie Microalgae Chlorella, and for Industrial Wastewater Treatment
Abstract: The use of solar energy for generation of the process of water electrolysis, permitting the oxygen and hydrogen gases production, concentration of the high-calorie fast productive Chlorella microalgae, and industrial wastewater treatment is the most promising direction today. This is explained by the complete absence of electrical energy consumption for the implementation of these industrial technological projects. No less interesting is the process of photosynthesis of phytoplankton cells, which also …
Published in International Journal of Advance in Molecular Engineering · Vol. 1, Issue 1, 2023 · pp. 7–21 Read article
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A Review on The Role of Nanoparticles in Modifying Mg Alloys and Composites
Abstract: Reviewing and assessing magnesium's uses in the automobile sector, which have the potential to greatly improve fuel efficiency and environmental preservation, is the goal of this study. The report provides an overview of magnesium alloys' present benefits, drawbacks, technological obstacles, and future prospects in the automobile sector. The development of magnesium matrix composites has advanced to a new level thanks to the magnesium matrix nanocomposites' exceptional mechanical qualities. Dispersing nanoparticles …
Published in International Journal of Fracture Mechanics and Damage Science · Vol. 2, Issue 1, 2024 · pp. 24–32 Read article
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Experimental Study on the Wear Mechanisms of Cutting Tools in High-Performance Machining
Abstract: Because high-performance machining (HPM) may increase output and improve product quality, it is essential for modern production. The quick wear of cutting tools under high-stress circumstances, however, presents serious difficulties that affect surface smoothness, tool life, and cost-effectiveness. Through an analysis of the impacts of cutting speed, feed rate, tool material, and cooling techniques, this work explores the wear processes impacting cutting tools in HPM. Advanced spectroscopy and microscopy procedures …
Published in International Journal of Fracture Mechanics and Damage Science · Vol. 2, Issue 1, 2024 · pp. 9–14 Read article
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Flaxseed and Diabetes Management: A Comprehensive Review of Recent Studies and Potential Mechanisms
Abstract: Diabetes mellitus, a condition characterized by chronic hyperglycemia, has become a significant global health challenge, leading to substantial morbidity and mortality rates. Dietary techniques are crucial for the effective control of diabetes, including both pharmaceutical and non-pharmacological therapies. Flaxseed (Linum usitatissimum) is one of the functional foods that has attracted a lot of interest because of its abundance of bioactive components, including lignans, dietary fiber, and alpha-linolenic acid (ALA). The …
Published in International Journal of Nutritions · Vol. 2, Issue 1, 2025 · pp. 24–32 Read article
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Improving the Mechanical and Interfacial Properties of Bhendi Fiber via Chemical Surface Treatments
Abstract: Because of its primary benefits—moderate strength and stiffness, low cost, and being a renewable, degradable, and ecologically friendly material—natural fibers are believed to have potential use as reinforcing agents in polymer composite materials. Due to their inherent hydrophilicity, they have a tendency to retain moisture, which can impair or soften the fibers' adhesion to the surrounding matrix. This can have an impact on the performance of composite materials used in …
Published in International Journal of Advance in Molecular Engineering · Vol. 3, Issue 1, 2025 · pp. 22–32 Read article
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Rapid Post-uterine Involution in Dairy Cows: Mechanisms, Dietary Strategies, and Impact on Postpartum Recovery
Abstract: The postpartum period in dairy cows is critical for reproductive success, with uterine involution playing a central role in returning the reproductive tract to its pre-pregnancy state. Rapid uterine involution is essential for improving reproductive performance and minimizing the risk of postpartum complications. This review explores the nutritional mechanisms that influence uterine involution, focusing on key dietary strategies to promote tissue repair and recovery. We examine the role of energy, …
Published in Emerging Trends in Metabolites · Vol. 2, Issue 2, 2025 Read article
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Vaccines in the Fight Against COVID-19: Mechanisms, Efficacy, and Global Challenges
Abstract: The SARS-CoV-2 pandemic has created an unparalleled public health problem, necessitating comprehensive prevention. This page discusses COVID-19's evolution, scientific understanding, and quick vaccine production and implementation. It compares the mechanisms, efficacy, and safety profiles of the four major types of COVID-19 vaccines—namely mRNA, viral vector, protein subunit, and inactivated virus vaccines. Each type is evaluated in terms of how it stimulates the immune response, its effectiveness in preventing infection or …
Published in Recent Trends in Infectious Diseases · Vol. 2, Issue 2, 2025 · pp. 34–48 Read article
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Advanced Security Mechanisms for AIDL Communication in High-Risk Environments
Abstract: Android Interface Definition Language (AIDL) serves as a critical component for inter-process communication (IPC) in Android systems, facilitating seamless interaction between different application components. However, in high-risk environments, such as military, healthcare, and financial systems, AIDL communication faces significant security challenges, including unauthorized access, data tampering, and privilege escalation. This paper presents a detailed review of the advanced security mechanisms designed to safeguard AIDL communication in such environments. We propose …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 4, Issue 1, 2026 Read article
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Plant-Derived Psychotropic Agents Targeting Neurotransmitter Systems: Pharmacognostic Evidence, Mechanisms, and Clinical Relevance
Abstract: Psychiatric health problems are also a large burden on global health and existing psychotropic drugs may be restricted by relative effectiveness, side effects, and inadequate long-term tolerability. Plant- based psychotropic agents have subsequently been the focus of interest in the form of complementary or alternative therapies. This review outlines the pharmacognostic, mechanisms of action and therapeutic importance of plant-based psychotropic agents against central neurotransmitter systems. The traditional medicinal practices give …
Published in International Journal of Brain Sciences · Vol. 3, Issue 1, 2026 · pp. 34–42 Read article
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Cosmetic Topical Formulations: Design Strategies, Skin Interaction Mechanisms, Clinical–Cosmetic Applications, and Emerging Trends
Abstract: Cosmetic topical products are central to modern skin care, as they deliver active ingredients directly to the skin surface and upper layers to improve appearance, texture, and function. By acting locally on the epidermis and adnexal structures, these preparations help manage dryness, photoaging, pigmentation, acne, and sensitive-skin conditions while minimizing systemic exposure. A wide range of dosage forms—creams, lotions, gels, ointments, serums, sprays, and transdermal-inspired cosmetic patches—are engineered to modulate …
Published in Recent Trends in Cosmetics · Vol. 3, Issue 2, 2026 · pp. 39–47 Read article
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Histoplasma capsulatum (Dimorphic Fungus) in India: Biological Features, Virulence Mechanisms, and Clinical Implications of Histoplasmosis.
Abstract: Histoplasmosis is a systemic mycosis caused by the thermally dimorphic fungus Histoplasma capsulatum. Infection is acquired primarily by inhalation of infectious microconidia and may range from asymptomatic infection to severe disseminated disease. Although histoplasmosis has classically been associated with the river valleys of the Americas, it is being increasingly recognized in Asia, including India, where it frequently mimics tuberculosis, leishmaniasis, lymphoma, and leprosy, resulting in delayed diagnosis and treatment. Cutaneous …
Published in International Journal of Fungi · Vol. 3, Issue 1, 2026 · pp. 38–48 Read article
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Partitioning Dynamics of Nutrients in Transition Dairy Cows: Metabolic, Hormonal, and Cellular Mechanisms Affecting Lactation and Fertility
Abstract: This review critically examines nutrient partitioning dynamics in dairy cows during the transition phase, a period that profoundly affects lactation and reproductive performance. During this phase, cows experience extensive physiological changes that alter nutrient requirements and utilization, making effective management essential for health and productivity. The review synthesizes current research on mechanisms of nutrient partitioning, with particular attention to energy, protein, and mineral balance, which are crucial for optimizing milk …
Published in International Journal of Nutritions · Vol. 3, Issue 1, 2026 Read article
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Early Life Nutrition as a Determinant of Long-Term Vaccine Immunogenicity in Livestock: Mechanisms, Practical Strategies, and Species-Specific Considerations
Abstract: Early life represents a critical period for immune system development in livestock, during which nutritional exposures can exert long lasting effects on vaccine immunogenicity. Although vaccination is a cornerstone of infectious disease control in food producing animals, marked variability in vaccine induced immune responses is frequently observed under commercial conditions. Growing evidence suggests that this variability is partly driven by differences in early nutritional status, which can influence immune maturation, …
Published in International Journal of Vaccines · Vol. 3, Issue 1, 2026 · pp. 15–26 Read article
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Photochemical Detoxification of Arsenic- and Mercury-Contaminated Soils: Geochemical Mechanisms and Pathways
Abstract: This study evaluates the geochemical aspects of soil detoxification in areas contaminated with arsenic (As) and mercury (Hg), emphasizing sustainable strategies for improving soil health and ensuring safe crop production. The research provides an ecological and toxicological assessment of regional soils and classifies them base on the concentration and mobility of toxic elements. Although the current levels of As and Hg do not yet present a critical risk to agricultural …
Published in International Journal of Photochemistry and Photochemical Research · Vol. 4, Issue 1, 2026 · pp. 06–10 Read article
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Network Pharmacology and Molecular Docking Approach to Reveal the Underlying Mechanisms of Isorhamnetin in the Treatment of Lymphangitis Carcinomatosis
Abstract: Objective: Lymphangitic carcinomatosis (LC) is a tumor that spreads through lung lymphatics and is most commonly seen secondary to adenocarcinoma. In the majority of cases, LC is a result of tumor cells spreading through the lymphatic system. However, approximately 20% of LC cases can be attributed to lymphangitis caused by tumors obstructing lymphatic drainage. This blockage commonly occurs near the lung hilum, where a centrally located mass can cause inflammation …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 1, Issue 1, 2023 · pp. 28–45 Read article