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135 articles for “Infection”
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Development of a Novel Therapeutic Approach Using RNA Interference for Targeting Viral Genes
Abstract: RNA interference (RNAi) is a ground breaking therapeutic strategy that holds immense promise for targeting viral genes in the treatment of viral infections. This approach leverages the natural gene-silencing mechanisms of RNAi to inhibit viral replication and expression at the molecular level, providing a precise and adaptable method to counteract viral pathogens, including influenza, HIV, and hepatitis viruses. Recent advancements in RNAi technology have enabled the development of highly specific …
Published in International Journal of Virus Studies · Vol. 1, Issue 2, 2024 · pp. 12–22 Read article
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Climate Change and the Spread of Pathogens: Implications for Public Health
Abstract: Climate change plays a significant role in the spread of infectious diseases by shifting how pathogens behave, affecting how vulnerable hosts are, and changing the way diseases are transmitted.Rising global temperatures, changing precipitation levels, and extreme weather events are accelerating the spread of bacteria, viruses, fungi, and parasites, increasing the risk of outbreaks worldwide. Warmer conditions favor the survival and expansion of vector-borne diseases such as malaria, dengue, and Zika …
Published in International Journal of Pathogens · Vol. 2, Issue 1, 2025 · pp. 1–5 Read article
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How Scientists Look for New Pathogens Before They Spread
Abstract: Emerging infectious illnesses are a persistent danger to global health. They often come from unexpected places, such wildlife reservoirs, changes in the climate, or human activities. Finding new diseases before they create epidemics is one of the biggest problems in modern epidemiology. This article talks about how scientists use genetic monitoring, field sampling, and real-time data processing to find, track, and describe new infectious organisms in a way that works …
Published in International Journal of Pathogens · Vol. 3, Issue 1, 2026 · pp. 11–17 Read article
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Innovative Vaccine Technologies: Current Landscape and Future Prospects in Preventive Medicine
Abstract: This review article presents a comprehensive analysis of recent advancements and emerging trends in vaccine development, offering insights into the dynamic landscape of preventive medicine. Delving into a spectrum of infectious diseases, including influenza, HIV/AIDS, malaria, tuberculosis, respiratory syncytial virus (RSV), Group B Streptococcus (GBS), norovirus, and chikungunya, the review highlights innovative approaches and breakthroughs in vaccine technology. It explores efforts to develop universal influenza vaccines, long-awaited HIV vaccines, and …
Published in International Journal of Vaccines · Vol. 1, Issue 2, 2024 · pp. 07–15 Read article
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Advancing Tropical Medicine: Interdisciplinary Approaches, Innovation, and Health System Strengthening
Abstract: Tropical medicine encompasses a diverse range of infectious diseases prevalent in tropical and subtropical regions, presenting complex challenges to global health. This review offers an extensive examination of critical aspects within tropical medicine, emphasizing recent progress and upcoming avenues of research. Interdisciplinary collaboration is highlighted as essential for addressing the multifaceted nature of tropical diseases, with healthcare professionals, veterinarians, ecologists, epidemiologists, and social scientists working together to tackle complex health …
Published in International Journal of Tropical Medicines · Vol. 1, Issue 2, 2024 · pp. 1–13 Read article
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Comparison Study of Non-Alcoholic Sanitizer and Alcohol Based Sanitizer
Abstract: Hand sanitizer is the best choice to maintain the hand hygiene and stopping the spread of infectious diseases. The active ingredient in traditional hand sanitizers is usually alcohol, but worries about flammability, skin irritation, and possible abuse have prompted the creation and growing popularity of alcohol-free substitutes. The purpose of this review is to objectively assess the safety, effectiveness, and usefulness of alcohol-free hand sanitizers. To successfully eradicate germs, alcohol-free …
Published in Recent Trends in Infectious Diseases · Vol. 2, Issue 1, 2025 · pp. 11–22 Read article
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The Role of Natural Products in Antiviral Drug Discovery: Insights into Mechanisms and Therapeutic Potential
Abstract: Drug discovery has always relied heavily on natural sources, especially when it comes to creating antiviral medications. This review explores the therapeutic potential of various natural products, including plant extracts, marine compounds, and microbial metabolites, in the fight against viral infections. We examine the mechanisms of action by which these natural compounds exert their antiviral effects, including direct inhibition of viral replication, modulation of host immune responses, and interference with …
Published in International Journal of Virus Studies · Vol. 1, Issue 2, 2024 · pp. 36–47 Read article
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Evaluation of Temporal Distribution of Recurrent Cholera Outbreak in Zambia.
Abstract: Background: Cholera cases in Zambia have been observed over a period without understanding the epidemiological cycles. The aim of the study was to evaluate the temporal distribution of recurrent cholera outbreak in Zambia from 1977 to 2019. Methods: Cholera case records of both sex and all ages were retrospectively analyzed. The primary source documents were reviewed including infectious diseases line list, notifiable diseases reports, Health Impact Assessment, District Health Impact …
Published in Recent Trends in Infectious Diseases · Vol. 2, Issue 1, 2025 · pp. 10–21 Read article
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Clinicians’ role in the prevention and management of neonatal candidiasis in Punjab: challenges and opportunities.
Abstract: Background: Neonatal candidiasis is a growing concern in Punjab, particularly among newborns in neonatal intensive care units. The increasing prevalence poses significant risks to neonatal health, highlighting the need for effective management and prevention strategies. Objective: This study aims to explore the role of clinicians in preventing and managing neonatal candidiasis in Punjab while identifying the key challenges they face in clinical practice. Methods: A structured questionnaire was distributed to …
Published in Recent Trends in Infectious Diseases · Vol. 2, Issue 2, 2025 · pp. 26–33 Read article
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Mathematical Modeling of Epidemics Using Stochastic Differential Equations: A Review
Abstract: The accurate modeling of infectious disease dynamics is crucial for predicting outbreaks and informing public health interventions. While deterministic models such as the SIR (Susceptible-Infected-Recovered) framework have traditionally been used to understand disease transmission, they often fail to account for the randomness inherent in real-world scenarios. Disease spread is influenced by numerous uncertain factors, including individual behavioral changes, environmental fluctuations, and imperfect data reporting. These uncertainties can significantly impact model …
Published in Recent Trends in Mathematics · Vol. 1, Issue 2, 2024 · pp. 1–6 Read article
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Host Invasion to Immune Evasion: Emerging Concepts in Pathogen Virulence Strategies
Abstract: Pathogens have evolved a wide repertoire of virulence strategies that allow them to invade host tissues, establish infection, and circumvent immune responses. From the initial steps of adhesion and colonization to complex molecular mimicry, antigenic variation, and immunomodulation, pathogens display remarkable adaptability. While traditional research has emphasized host cell entry and toxin production, emerging evidence highlights subtler and more dynamic strategies such as manipulation of host signaling pathways, subversion of …
Published in International Journal of Pathogens · Vol. 2, Issue 2, 2025 Read article
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Scientific Trajectories in Indian Virology: Innovations, Institutions, and Impact
Abstract: India's substantial research on epidemiology, virology, and public health measures has helped the world understand viral infections better. This article gives an overview of virus research in India, starting with early studies on arboviruses and enteroviruses and going all the way up to current studies on new and re-emerging pathogens including SARS-CoV-2, Nipah, and Zika viruses. Over the decades, India has built a rich legacy in virus research through pioneering …
Published in International Journal of Vaccines · Vol. 2, Issue 2, 2025 · pp. 11–20 Read article
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Nutrition Induced Gut Microbiota Modulation in Food Animals: Implications for Viral Susceptibility, Shedding and Transmission Dynamics for Sustainable Development
Abstract: The gut microbiota has emerged as a central mediator linking host nutrition, immune competence, and vulnerability to viral pathogens in food animals. Diet is a primary driver of microbial community structure and function, influencing metabolite production, intestinal barrier integrity, and systemic antiviral immunity. Accumulating evidence indicates that nutrition induced modulation of the gut microbiota can substantially alter viral susceptibility, replication, and shedding patterns, with downstream effects on transmission dynamics within …
Published in International Journal of Virus Studies · Vol. 3, Issue 1, 2026 · pp. 46–56 Read article
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Emerging Trends in Horticultural Crops: Role of Date Fruit in Promoting Urinary and Kidney Health
Abstract: Dates, or Phoenix dactylifera L., have been widely consumed in different cultures, both as a food source and for their health benefits. Whereas dates have been reported extensively to improve cardiovascular, gastrointestinal, and metabolic function, their role in urinary tract and renal health has received lesser attention in mainstream nutritional sciences. This review systematically evaluates and synthesizes the current literature on the potential effects of dates to promote urinary health …
Published in International Journal of Trends in Horticulture · Vol. 3, Issue 1, 2026 · pp. 24–32 Read article
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Lysogenic Phage Cocktails with Embedded Fluorophores for Field Wound Diagnostics.
Abstract: Rapid and accurate detection of wound infections in field settings remains a critical challenge in emergency and military medicine. Conventional microbiological diagnostics are time- consuming and laboratory-dependent. Bacteriophages, particularly lysogenic phages, offer high specificity toward bacterial hosts and can be engineered as diagnostic tools. A translational framework was developed for lysogenic bacteriophage cocktails embedded with fluorophore reporters for rapid, point-of-care wound diagnostics. Mechanisms of phage infection, lysogenic integration, and fluorophore …
Published in International Journal of Virus Studies · Vol. 3, Issue 2, 2026 Read article
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The Effects of HIV/AIDS Worldwide
Abstract: The Human Immunodeficiency Virus (HIV), which targets immune system conductors (CD4 cells), has infected millions throughout the world. HIV lowers the body's defences by infecting certain bodily fluids (blood, sperm, vaginal fluids, and breast milk) through unprotected sex, contaminated needles, or mother-to-child transmission. Early flu-like symptoms may go unrecognised, but if not treated, HIV advances to AIDS, which is characterised by severe immune system impairment. However, advances in antiretroviral therapy …
Published in International Journal of Virus Studies · Vol. 1, Issue 1, 2024 · pp. 26–31 Read article
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Histoplasma capsulatum (Dimorphic Fungus) in India: Biological Features, Virulence Mechanisms, and Clinical Implications of Histoplasmosis.
Abstract: Histoplasmosis is a systemic mycosis caused by the thermally dimorphic fungus Histoplasma capsulatum. Infection is acquired primarily by inhalation of infectious microconidia and may range from asymptomatic infection to severe disseminated disease. Although histoplasmosis has classically been associated with the river valleys of the Americas, it is being increasingly recognized in Asia, including India, where it frequently mimics tuberculosis, leishmaniasis, lymphoma, and leprosy, resulting in delayed diagnosis and treatment. Cutaneous …
Published in International Journal of Fungi · Vol. 3, Issue 1, 2026 · pp. 38–48 Read article
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Antimicrobial Resistance and AI-Based Strategies for Rapid Pathogen Detection
Abstract: Antimicrobial resistance (AMR) has become a major global health threat, significantly reducing the effectiveness of antimicrobial therapies and increasing the burden of infectious diseases worldwide. The rapid emergence of multidrug-resistant pathogens has created an urgent need for faster, more accurate, and scalable diagnostic approaches to support timely treatment and effective infection control. Artificial intelligence (AI) has emerged as a promising technology capable of transforming pathogen detection and AMR surveillance through …
Published in Recent Trends in Infectious Diseases · Vol. 3, Issue 2, 2026 · pp. 26–36 Read article
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The Emergence of Coxsackievirus A16 Associated with HFMD Colloquially Termed ‘Tomato Flu’ in India 2022: A Detailed Virological Inspection
Abstract: As the world battles the COVID-19 pandemic and grapples with a concerning spike in monkeypox cases, India has encountered another viral illness dubbed "Tomato Flu." Tomato Flu is a viral disease caused by coxsackievirus A16, which is a highly infectious illness affecting children under 10 years old.. Enterovirus A71, CV-A16, CVA6, and echoviruses are the causes of what is also referred to as hand, foot, and mouth disease (HFMD). The …
Published in International Journal of Vaccines · Vol. 1, Issue 1, 2024 · pp. 29–40 Read article
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Disease: A Major Stumbling Block in the Growth of Aquaculture
Abstract: Aquaculture plays a crucial role in ensuring food security, fostering economic development, and providing recreational opportunities worldwide. However, the intensification of aquaculture practices has led to a surge in environmental challenges, including water pollution, soil acidification, eutrophication, chemical contamination, and the spread of diseases. Among these, diseases caused by bacteria, viruses, fungi, and parasites pose significant threats to the sustainability of global aquaculture. Despite the implementation of various diagnostic methods …
Published in International Journal of Marine Life · Vol. 1, Issue 1, 2024 · pp. 25–28 Read article