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1046 articles for “regulation”
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Exploring the Potential of Allium sativum Phytocompounds as B-Cell Leukemia 2 Inhibitors in Acute Lymphoblastic Leukemia: Molecular Docking Study
Abstract: Objective: Acute lymphoblastic leukemia (ALL) is a lymphoid progenitor cell malignancy that could be treated with plant-based drugs, thus alleviating the off-target effects caused by conventional chemotherapy. Since ancient days, Allium sativum has been an integral part of traditional medicine and an excellent antimicrobial, antioxidant, and antiproliferative agent. Hence, this study aims to assess the anti-leukemic potential of A. sativum phytoconstituents as the B-cell leukemia 2 protein (Bcl-2) natural inhibitor …
Published in Research and Reviews : Journal of Computational Biology · Vol. 13, Issue 2, 2024 · pp. 53–80 Read article
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Stingless Honeybee’s Rare Sugar and PCSK 9 - LDLR Interaction, A New Hope for Hormone Dependent Breast Cancer Patients – An In-silico Study
Abstract: Hypercholesterolemia is a lipid disorder characterized by elevated levels of low-density lipoprotein (LDL), commonly known as "bad" cholesterol. This condition is a significant risk factor in the development and progression of hormone-dependent breast cancer, as well as in the emergence of resistance to hormonal therapy. One of the key regulators of cholesterol metabolism is the proprotein convertase subtilisin/kexin type-9 (PCSK9) protein, which facilitates the degradation of the LDL receptor (LDLR) …
Published in International Journal of Cheminformatics · Vol. 3, Issue 1, 2025 · pp. 1–6 Read article
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Clean Energy Policy and Some Implications for Low-income communities
Abstract: Undeniably, we are moving away from the fossil fuels-based economy due to the extreme climate and weather catastrophes our communities in different areas of the world are experiencing. The solution for future generations is the transition to clean energy. How does that look for overburdened communities? It is an equality and environmental justice concept to make it inexpensive and available to everyone. Policy makers are now creating bills and pushing …
Published in Journal of Energy, Environment & Carbon Credits · Vol. 14, Issue 3, 2024 · pp. 15–21 Read article
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Design And Optimization Of High-Speed Array Multiplier
Abstract: An array multiplier is a digital circuit used for the rapid multiplication of binary numbers. It employs an array of logic gates to generate partial products concurrently, significantly enhancing speed. The array structure divides the multiplication task into smaller, parallel processes, allowing for efficient parallel processing of multiple bits. Each cell within the array manages specific bit-level multiplications, and their results are summed to produce the final product. This parallel …
Published in Journal of Microelectronics and Solid State Devices · Vol. 11, Issue 3, 2024 Read article
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Infrared Radiation: A Non-Invasive Approach to Cholesterol Measurement
Abstract: Cholesterol levels and Diabetes have become prevalent worldwide. People who are physically disabled or unresponsive need to have their glucose and cholesterol levels constantly checked because it is hard to get accurate readings through invasive procedures or blood samples. Based on the proposed model, Hyperglycemia and Cholesterol amounts might be found without touching or taking blood specimens. The Arduino UNO and basic infrared sensors are used to make this happen. …
Published in Research and Reviews: A Journal of Medicine · Vol. 14, Issue 3, 2024 · pp. 28–34 Read article
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Enhancing Safety Protocols in Industrial Operations
Abstract: Industrial safety is a crucial aspect of maintaining both operational efficiency and protecting the workforce in hazardous environments. Despite significant advancements in safety technologies and regulatory frameworks, industrial accidents remain a persistent problem, often leading to severe injuries, fatalities, and financial losses. Such incidents typically arise from a combination of factors, including human error, equipment malfunctions, and insufficient safety protocols. In response to these challenges, this paper examines key strategies …
Published in Journal of Industrial Safety Engineering · Vol. 11, Issue 3, 2024 · pp. 1–5 Read article
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Evaluation of Emergency Response Plans in Industrial Environments Using Simulation Techniques
Abstract: Industrial facilities, particularly those in the chemical, manufacturing, and energy sectors, face significant hazards due to their complex operations and the handling of hazardous materials. Ensuring the safety of workers and minimizing the impact of incidents require robust and effective emergency response plans (ERPs). Traditional evaluation methods, such as drills and tabletop exercises, often fall short in replicating the complexities of real-world emergencies. These methods may lack the realism needed …
Published in Journal of Industrial Safety Engineering · Vol. 11, Issue 3, 2024 · pp. 6–10 Read article
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Bio-Inspired Membranes in Oral Drug Delivery: A Pathway to Enhanced Permeability and Targeted Therapy
Abstract: Bio-inspired membranes in oral drug delivery represent a significant advancement in pharmaceutical technology, harnessing principles of natural biological systems to improve drug permeability, bioavailability, and targeted release. This review discusses the design, materials, and fabrication techniques used in bio-inspired membranes, with a focus on materials like chitosan, silk fibroin, and synthetic polymers that mimic biological structures. By exploring the mechanisms of drug permeation, such as mucoadhesion and selective permeability, bio-inspired …
Published in International Journal of Membranes · Vol. 1, Issue 2, 2024 · pp. 39–52 Read article
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Gut Feelings: Unravelling the Secrets of the Microbial Universe Within
Abstract: The human digestive system hosts a varied and dynamic community of microorganisms, commonly known as the gut microbiota. This complex community, which includes various organisms such as bacteria, archaea, viruses, and fungi, is essential and important for numerous bodily functions such as metabolism, immune response, and cognitive development. The composition and vast diversity of the gut microbiome are shaped by diet, lifestyle, and genetic factors. Disruptions in this balance, known …
Published in Research and Reviews : A Journal of Immunology · Vol. 14, Issue 3, 2024 · pp. 21–33 Read article
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Strengthening Low Voltage Ride-Through in Wind Energy Systems: A Comparative Study of DVR and STATCOM
Abstract: This study looks at the various methods used to improve the low-voltage ride-through (LVRT) capabilities of wind turbine systems (WT) that are based on double-fed induction generators (DFIG). The Type-III WT machine, which is mostly based on DFIG, is instantly connected to the grid without the digital power interface, making the terminal voltage or reactive electricity output unmanageable. This is because the world utilizes between 20% and 25% of renewable …
Published in Journal of Power Electronics and Power Systems · Vol. 14, Issue 3, 2024 · pp. 47–62 Read article
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Toward Comprehensive Immunization: The Role of Combined COVID-19 and Influenza Vaccines in Public Health
Abstract: The emergence of multi-pathogen vaccines, particularly those combining protection against COVID- 19 and influenza, marks a significant advancement in immunization efforts. These combination vaccines have the potential to streamline vaccination processes, improve vaccine uptake, and reduce the burden on healthcare systems by offering a single dose that targets both viruses. COVID-19 and seasonal influenza are major public health concerns, with overlapping symptoms and seasonal patterns that justify the rationale for …
Published in International Journal of Vaccines · Vol. 2, Issue 1, 2025 · pp. 9–17 Read article
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Health Justice and Governance: Social and Legal Aspects
Abstract: Health justice and governance are central to efforts in addressing the social determinants of health, legal determinants of health, promoting equitable access to healthcare and safeguarding the interests of all people. In this paper, we delve into the complex relationship between health justice and governance through laws, policies and community involvement necessary to ensure health equity. This publication explores the impact of social determinants like socio-economic status, education and environment …
Published in Research and Reviews: A Journal of Health Professions · Vol. 14, Issue 3, 2024 Read article
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Molecular Docking of Nigella Sativa Phytocompound as Inhibitors of Transcription Factors NF-KB Implicated in Rheumatoid Arthritis
Abstract: Objectives: Nigella sativa, a plant considered around the world as the most treasured nutrient-rich herb for centuries together in different civilizations, is exceptionally known for its high levels of antioxidant properties. Free radical intensification due to oxidative stress plays a key role in the pathogenesis of rheumatoid arthritis by activating the NF-KB protein that regulates the expression of the genes involved in inflammation. Methods: This study involves in-silico approach to …
Published in International Journal of Molecular Biotechnological Research · Vol. 2, Issue 2, 2024 · pp. 42–55 Read article
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Enhancing Wildlife Tourism Management Using Deep Learning and Particle Swarm Optimization (PSO) for Animal Detection in Wildlife Sanctuaries
Abstract: Wildlife tourism is one of the most thriving sectors, faced with huge challenges in terms of safeguarding protected areas. As demand for wildlife experiences accelerates, it becomes necessary to find efficient measures that are friendly to conservation. The use of these advanced techniques in this field such as YOLO and PSO algorithm presents a new dimension on managing wildlife tourism. To harness the abilities of these techniques, this research centers …
Published in Current Trends in Signal Processing · Vol. 14, Issue 3, 2024 · pp. 41–50 Read article
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Thermal Behavior and Insulation Strategies for Li-FeS₂ Thermal Batteries: An ANSYS Simulation Study
Abstract: Thermal batteries are special electrochemical systems in which a great amount of energy is delivered during a relatively short period of time. The holding time of the thermal battery's working temperature and cell temperature define its discharge life. Thermal batteries have their advantages comparing other type of batteries, so they are used for several purposes including military field. Thermal batteries usually operate in the internal temperature range of 400 to …
Published in Journal of Thermal Engineering and Applications · Vol. 11, Issue 3, 2024 · pp. 45–52 Read article
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A Review on Banana Fiber Reinforced Polymer Composites through Advanced Surface Treatments and Manufacturing Techniques
Abstract: In today's rapidly evolving world, heightened environmental concerns and stringent government regulations have spurred scientists and researchers to seek biodegradable and renewable alternatives to synthetic materials. Natural fibers, derived from resources like banana, jute, bagasse, and sisal, offer distinct advantages such as low density, comparable strength, non-toxicity, cost-effectiveness, and minimal waste disposal issues over synthetic counterparts. Extensive research has explored the potential applications of these natural fibers, with banana fibers …
Published in Trends in Mechanical Engineering & Technology · Vol. 14, Issue 3, 2024 Read article
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Raspberry Pi-based Self-driving Car Technologies: A Review of Hardware and Software Integration
Abstract: An assessment of the state, possibilities, and difficulties of self-driving car technology. Autonomous vehicles (AVs), also referred to as self-driving cars, are automobiles that can navigate and function without the need for human involvement. They make decisions, sense their environment, and traverse routes safely by combining sensors, cameras, radar, lidar, and sophisticated algorithms. The advancement of autonomous vehicles holds the capacity to completely transform the transportation sector by enhancing security, …
Published in International Journal of Electronics Automation · Vol. 2, Issue 2, 2024 · pp. 1–6 Read article
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Enhancing Road Safety: A System for Vehicular Accident Detection, Prevention, and Rescue Alerts
Abstract: The Vehicular Accident Detection, Prevention, and Rescue Alert System is a comprehensive solution aimed at bolstering road safety by integrating multiple advanced technologies. It merges drowsiness detection, alcohol level monitoring, and instant emergency alerts to mitigate accidents and expedite rescue efforts. Modern computer vision and machine learning techniques are used by the Drowsiness Detection Alarm to track driver conduct and spot drowsiness indicators. Upon detecting drowsiness, an immediate alarm is …
Published in International Journal of Solid State Innovations & Research · Vol. 2, Issue 2, 2024 · pp. 7–11 Read article
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Assessment of Vitamin D Levels Among Hashimoto and Hypothyroidism Disease in Iraq, A Comparative Study
Abstract: The thyroid gland is a small gland that regulates the body’s metabolism. It secretes the hormones that the body needs to maintain this process. People of different ages may be afflicted with thyroid diseases, including Hashimoto disease and hypothyroidism. The current study aimed to compare the levels of vitamin D among patients with Hashimoto’s disease and hypothyroidism coming to the Diabetes and Endocrinology Center in Al-Sadr Medical City in Najaf …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 14, Issue 3, 2024 · pp. 77–83 Read article
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Environmental Pollutants and Biodiversity Loss: Analyzing the Role of Persistent Organic Pollutants in Ecosystem Decline
Abstract: Persistent Organic Pollutants (POPs) significantly impact biodiversity, with various factors influencing their effects on species and ecosystems. Species in poor body condition, like carnivores and predators, are more vulnerable to POPs due to weakened immune systems and reduced detoxification abilities. Dietary habits also affect the accumulation of POPs, as chemicals biomagnify up the food chain. Carnivores accumulate higher concentrations, leading to reproductive failures, hormonal imbalances, and death, while herbivores face …
Published in International Journal of Toxins and Toxics · Vol. 2, Issue 1, 2025 · pp. 9–20 Read article