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1068 articles for “selection”
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An AAV Vector for Inducible Gene Expression Preferentially in Muscles
Abstract: Adeno associated viral (AAV) vectors has been used widely in gene therapy and efforts have been made to improve their utility by adding genetic elements that would enable targeting transgene expression to particular cells or tissues of interest and permitting on/off regulation of expression. In this study, we designed a recombinant AAV9 variant PHP.eB vector with muscle creatine kinase (Mck)-derived enhancers, a synthetic muscle-expression promoter, in combination with a third-generation …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 1, Issue 2, 2023 · pp. 46–61 Read article
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Extrapolations of Periwinkle Secondary Metabolites as Multitarget Inhibitor of Breast Cancer Proteins
Abstract: Objective: Breast cancer is considered one of the most common and dangerous forms of cancer. It is a significant public health issue on a global scale. The study estimates that 10.0 million people will die from cancer this year, and 19.3 million people will develop the disease overall (BC). In this computation approach, nowadays emphasizes new drug discovery, the target protein epidermal growth factor receptor (EGFR) (5UGB), estrogen receptor (ER) …
Published in International Journal of Biochemistry and Biomolecule Research · Vol. 1, Issue 1, 2023 · pp. 36–49 Read article
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Solar Powered Irrigation System Design with Venturimeter for Utilizing Natural Resources
Abstract: This research focuses on enhancing crop productivity in agriculture by ensuring high quality and quantity of crops. Crops needs to be given adequate nutrients in an efficient and timely fashion as a way to accomplish this.. Thus, liquid-based fertilizers are selected for this purpose. However, farmers often face challenges in supplying fertilizers with the required quantity and precision. To address this issue, we propose a solution that leverages solar energy …
Published in International Journal of Energy and Thermal Applications · Vol. 1, Issue 1, 2023 · pp. 29–35 Read article
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Inhibition of PI3K/Akt/mTOR Signaling Pathway by Vitis Vinifera Phytocompounds: A Promising Strategy for Supressing Colorectal Cancer Growth and Metastasis
Abstract: Objectives: Colorectal cancer was not typically identified a few decades ago. Today, with almost 900 000 fatalities each year, it is the fourth most dangerous cancer in the world. Colorectal cancer is responsible for about 10% of all cancer diagnoses annually and cancer-related deaths worldwide. It is the second most common type of cancer in women and the third most common type in men. Incidence and death are roughly 25% …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 1, Issue 2, 2023 · pp. 64–75 Read article
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Prototype Model Development and Design Analysis of A Solar Tricycle for Physically Challenged People in India
Abstract: Society is greatly concerned about the mobility of individuals with physical disabilities. The scarcity of energy resources and the issue of pollution are currently the primary concerns. These issues can be resolved by employing alternative energy sources such as solar power. This paper presents an overview of the existing solar tricycles designed for those with disabilities. It also improves a handicapped-friendly solar-powered tricycle. The goal is to reduce handicapped people's …
Published in International Journal of Mechanical Dynamics and Systems Analysis · Vol. 1, Issue 1, 2023 · pp. 43–56 Read article
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Experimental Investigation of Aerodynamic Characteristics of Dimpled 3D Aircraft Wing
Abstract: There is a strong demand for innovative designs, optimization of the aircraft components for their parts with respect to design, etc. One such innovation is by introduction of dimples in the wing of the aircraft. To study the effect of geometry modification of the wing, the present work compares the aerodynamic efficiency, ratio of lift to drag coefficients, along with different aerodynamic characteristics of an Inward and outward circular dimpled …
Published in International Journal of Mechanical Dynamics and Systems Analysis · Vol. 1, Issue 1, 2023 · pp. 11–22 Read article
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Optimizing Cellular Manufacturing Systems: Minimizing Production Time with Collaborative Robots (Cobots) using PSO
Abstract: This study focuses on the implementation of cobots in a cellular manufacturing system to minimize production time. The use of cobots, collaborative robots capable of working alongside human operators, aims to increase efficiency and reduce manual labor in the manufacturing process. The mathematical model presented in this research evaluates the impact of cobots on production time by considering various factors, including task times, machine setup, inspection, waiting, and idle times. …
Published in International Journal of Industrial and Product Design Engineering · Vol. 1, Issue 1, 2023 · pp. 22–27 Read article
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QR Code Application for Hardware Devices
Abstract: There are numerous variations of QR code symbols, including logo QR codes, encrypted QR codes, and iQR Codes, so users can select one that best suits their needs. A QR code is used these days in a variety of application streams linked to marketing, security, academia, etc., and is rapidly gaining popularity. More people are becoming aware of this technology and using it appropriately daily. With the increase in smartphone …
Published in International Journal of Electronics Automation · Vol. 1, Issue 1, 2023 · pp. 14–21 Read article
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Effectiveness of Sensitization Program on Knowledge of School Children Regarding Refractive Errors
Abstract: The human eyes are portals of absorbing divine knowledge from the surrounding world. These two precious pearls need to take proper care throughout to taste life. The eye care starts right from birth onward and becomes keenly required in children's school age as they use these gifts for intense learning. The neglected care in the initial years may trouble them with various visual disorders and disturb their studies too. Well-structured …
Published in Recent Trends in Infectious Diseases · Vol. 1, Issue 1, 2024 · pp. 13–20 Read article
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Facilitated Deferred Transmmission a Risk to Public Health of Globalization and Intercountry Adoptions of Pets
Abstract: Increased temperatures due to climate change may be facilitating that arthropods vectors of zoonotic diseases rapidly colonize new territories. 6472 dogs have been selected to check main Mediterraneum zoonotic vector-borne, two transmitted by fly bites, Leishmaniasis and Dirofilariasis, and tree transmitted by ticks, Ehrlichiosis, Anaplasmosis, and Babesiosis through IFA, ELISA, PCR and microscopy tests and calculate the ratio of this diseases hosts as well the destinations in north of Europe …
Published in Recent Trends in Infectious Diseases · Vol. 1, Issue 1, 2024 · pp. 21–26 Read article
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Knowledge and Practice of Rural Population Regarding Mosquito Control Measures: A Descriptive Study
Abstract: The research aimed to evaluate the understanding and implementation of mosquito control strategies among the rural inhabitants in specific wards of the Athirampuzha panchayath. The study aimed to achieve the following objectives: evaluate the understanding of mosquito control measures among the rural population, analyze the implementation of mosquito control measures by the rural population, and investigate potential correlations between the rural population's knowledge of mosquito control measures and various demographic …
Published in International Journal of Evidence Based Nursing And Practices · Vol. 1, Issue 2, 2023 · pp. 14–18 Read article
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Oral Self-examination: An Approach for Early Recognition of Oral Cancer Among Factory Workers: An Experimental Study
Abstract: Background: Cancer is a worldwide concern and ranks among the most dreaded illnesses across the globe. Oral cancers are one common cancer among all cancers. Objectives: To measure the existing knowledge concerning oral self-examination for timely recognition of oral cancer among factory workers and to develop and administer a planned health education programme of oral self-examination for early recognition of oral cancer among factory workers. 40 factory workers were selected …
Published in International Journal of Oncological Nursing and Practices · Vol. 1, Issue 2, 2023 · pp. 22–26 Read article
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Event Tent: A Hall Booking Communication Website
Abstract: We designed this project to help Hall business to provide extra functionality and to make the work go faster and to decrease the pressure on the owner as well as the customer. In addition, this project will help owners, staff, and other people to select any hall they want, and they can book the hall from anywhere via Event Hall Website, and there will be no need to visit the …
Published in International Journal of Electrical and Communication Engineering Technology · Vol. 1, Issue 1, 2023 · pp. 29–35 Read article
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Recent Update on Advanced Drug Delivery System
Abstract: Over the past decade, there has been a growing interest in the use of artificial intelligence (AI) technology for analysing and interpreting biological or genetic data, accelerating drug discovery, and identifying selective small-molecule modulators or rare molecules in addition to predicting their behaviour. The use of artificial neural networks (ANNs) for the rapid analysis of massive amounts of data, the development of novel hypotheses and treatment plans, the prediction of …
Published in International Journal of Advance in Molecular Engineering · Vol. 1, Issue 1, 2023 · pp. 22–30 Read article
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Multi-Response Optimization of Turning Parameters with Vikor-Entropy Method on Machining of AA6061-TiB2 In-Situ Composites
Abstract: In the manufacturing and metal cutting industries, the quality of the surface and strength is essential in defining the surface finish; an excellent surface finish indicates excellent quality in the product. The influence of machining parameters speed, feed and depth of cut on responses like material removal rate, surface roughness and Power consumption on turning of AA6061-TiB2 composites is investigated using the VIKOR-ENTROPY method. The effects of changing parameters on …
Published in Journal of Polymer & Composites · Vol. 11, Issue 8, 2023 · pp. 256–268 Read article
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Evaluation of Prescribing Pattern of Drugs in Hemodialysis Patients
Abstract: Background: Patients undergoing hemodialysis often exhibit a high level of dependency and frequently present with multiple co-morbid conditions Chronic kidney disease (CKD) poses a significant global public health challenge, with its association with numerous complications. Prescribing medications appropriately for individuals with CKD presents a substantial challenge. Objective: The study aimed to assess the prescribing patterns of drugs in hemodialysis patients. Results: Out of the total 82 selected patients, 42 (51%) …
Published in International Journal of Antibiotics · Vol. 1, Issue 2, 2024 · pp. 20–26 Read article
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Tools, Modern Drugs, and Latest Investigations for the Diagnosis and Treatment of Heart Failure: A Systematic Review of the General Causes
Abstract: Heart failure (HF) diagnosis and treatment present formidable challenges, given the absence of a definitive single test. This systematic literature review aims to comprehensively analyze the current landscape of diagnostic tools, modern drugs, and latest investigative approaches in HF management. Recognizing the complexity of HF etiology, this systematic review emphasizes the importance of advanced diagnostic methods, such as genetic testing and artificial intelligence applications. The systematic review was conducted to …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 13, Issue 1, 2024 · pp. 1–10 Read article
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Efficient Fault Detection in Power Transmission: A Review of Three-Phase Line Fault Detection with Hybrid Energy using MATLAB
Abstract: In urban regions, the density of power demand has significantly increased recently. Large-scale subterranean power cable installations are beginning to take the place of overhead transmission lines everywhere in the world because of environmental concerns in highly populated areas. The present project's primary objective is to use MATLAB to create a simulation model that includes 3ph symmetrical and unsymmetrical defects. Some have proven to be effective in detecting errors while …
Published in International Journal of Electrical Power and Machine Systems · Vol. 1, Issue 1, 2023 · pp. 42–47 Read article
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Searchable Encryption Based on Key Aggregation
Abstract: The ability to selectively distribute data with individuals in public cloud services may alleviate safety concerns about inadvertent privacy violations in cloud storage. The need for flexibility in sharing specific sets of documents with various user groups requires the use of distinct encryption keys for each document. This undertaking tackles practical difficulties by presenting the notion of Key-Aggregate Searchable Encryption (KASE). Natural language processing was used to extract essential phrases …
Published in International Journal of Data Structure Studies · Vol. 2, Issue 1, 2024 · pp. 21–25 Read article
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Evaluation of the anti diabetic effects of ethanolic root extract from polyalthania longifora in diabetic rats induced by streptozotin and nicotinamide with considaertion of toxocological aspects
Abstract: The root of Polialthia Longifolia was selected for the evaluation of antidiabetic potential in STZ-nicotinamide induced diabetic rat model.The root extract was extracted by hot percolation using ethanol as a solvent in soxhlet apparatus and the preliminary phytochemical screening was performed and it shows that the ethanolic root extract of Polialthia Longifolia contains alkaloids, glycosides, flavonoids and tannins. Safety profile is essential for the drugs obtained from the plant origin. …
Published in Research and Reviews: A Journal of Toxicology · Vol. 14, Issue 1, 2024 · pp. 37–50 Read article