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421 articles for “Uses Pharmacological”
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A Review Article on Genetic Testing, Types and Their Applications in Diseases
Abstract: Genetic testing, a medical test identifies changes in chromosomes, genes or proteins. The result of a genetic test result helps us to confirm or rule out any suspected genetic disorder and determine susceptibility of a person for a genetic disorder. Prenatal testing can be used to diagnose the changes which include neural tube defect and genetic disorders like Down’s syndrome that may occur in a zygote’s gene or chromosome even …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 7, Issue 3, 2017 · pp. 34–41 Read article
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Effect of Chronic Inescapable Footshock and Antidepressant Treatment on BDNF/TrkB Levels in Rat Hippocampus
Abstract: Depression is a major health problem globally. Chronic stress arising out of life style or social factors may trigger depression, the molecular basis of which has been attributed to alterations of brain chemicals like neurotrophins. Among these neurotrophins, brain-derived neurotrophic factor regulates many physiological functions in the brain, alteration of which has been well associated with the pathogenesis of depression. Stress-induced helplessness in rodents constitutes a well-defined model to investigate …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 2, Issue 2, 2012 · pp. 12–21 Read article
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An Experimental Study to Determine the Rasapanchaka of Zornia gibbosa Span
Abstract: Zornia gibbosa Span a member of fabaceae family, locally known as Nellujollusoppu/Haradahacchaga is widely used in the treatment of fracture by folklore practitioners of Udupi district, Karnataka. The present experimental study was carried out to evaluate Rasapanchaka of Zornia gibbosa Span (Samyojaki) by making use of human volunteers and animal experimentations. In order to incorporate the drug in Ayurvedic pharmacopeia it is essential to understand the Panchabhautic composition of Zornia …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 3, Issue 2, 2014 · pp. 1–7 Read article
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Potential Application of Retama sphaerocarpa Plant in Pharmaceuticals
Abstract: The aim of this study was to evaluate the phytochemical and biological activity (antibacterial and antifungal) of Retama sphaerocarpa plant and the possibility to use it in pharmaceutical formulations. This plant is traditionally used only as healing remedies because of their antiseptic, antipyretic and antidiarrheal properties. Phytochemical screening of leaves and stems revealed the presence of flavonoids, alkaloids, tannins and steroids. The antimicrobial activity was determined on bacterial strains such …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 9, Issue 3, 2019 · pp. 22–28 Read article
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Risk & Opportunities in Development of new Drugs: A New Perspective
Abstract: The procedures of drug discovery and development are briefly described in this article. Our goal is to assist researchers whose work may be pertinent to the discovery and/or development of new drugs in framing their research reports in a way that appropriately situates their findings within the drug discovery and development process and supports the efficient translation of preclinical research to humans. One overarching theme of our article is the …
Published in Recent Trends in Infectious Diseases · Vol. 1, Issue 2, 2024 · pp. 19–28 Read article
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Protein-Tyrosine Phosphatase-1B (PTP-1B) Inhibitory Perspectives of Hydroxylated Chalcones: Exploration through Docking Studies
Abstract: The current research emphasized on exploring the Protein-Tyrosine Phosphatase-1 B (PTP-1B) inhibitory potentials of hydroxylated chalcone derivatives against PDB ID: 4I8N (PTP-1B in complex with an inhibitor [(4-{(2s)-2-(1,3-benzoxazol-2-yl)-2-[(4-fluorophenyl)sulfamoyl]ethyl}phenyl)amino](oxo)acetic acid) by molecular docking approach using the iGEMDOCK (Genetic Evolutionary Method for Molecular Docking) software. The current molecular docking analysis of some hydroxylated chalcone derivatives have presented a profound inhibition of the antidiabetic target PTP-1B by interacting with the amino acid residues …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 6, Issue 1, 2019 · pp. 4–8 Read article
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Diversity of Agaricaceae (Basidiomycota: Agaricales) in Dharampur and Kaprada Taluka, Valsad District: A Taxonomic Study
Abstract: The fungal diversity of Dharampur and Kaprada Taluka in Valsad District, Gujarat, India, particularly within the Agaricaceae family, has been extensively studied. According to a standard reference text, the Agaricaceae contains 85 genera and 1340 species. Agaricaceae fungi, categorized as macrofungi, are prevalent in this region and are notably utilized by local tribal communities for culinary purposes due to their edibility. The life cycle of Agaricus is cyclic beginning with …
Published in International Journal of Fungi · Vol. 1, Issue 1, 2024 · pp. 51–62 Read article
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A Case Report on Ceftriaxone Induced Immediate Allergic Reaction
Abstract: The most common classes of drugs causing hypersensitivity reaction are antibiotics especially β-lactam antibiotic: cephalosporin’s and penicillin’s. Ceftriaxone, a third generation cephalosporin is used for variety of infections. This drug is associated with rare as well as mild side-effects such as urticaria, skin rash, diarrhea, vomiting, transient neutropenia, and hemolytic anaemia etc. We hereby try to present an adversary case report of a 19 years old male patient in which …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 10, Issue 2, 2020 · pp. 33–35 Read article
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Computational Exploration of Bhrijraj-derived Phytochemicals as Potential Anti-inflammatory Agents: A Molecular Docking Study with Cyclooxygenase-II Complex
Abstract: The molecular docking analysis was meticulously conducted using state-of-the-art computational tools, notably Chimera and Python. These tools were employed to unravel the complex interactions between the identified phytochemicals from Bhrijraj and the target protein, COX-II. The 3D structures of the phytochemicals were prepared with precision using ChemSketch, ensuring accuracy in the subsequent molecular docking simulations. This rigorous approach enhances the reliability and validity of the findings. This research aims to …
Published in Research and Reviews : Journal of Computational Biology · Vol. 13, Issue 1, 2024 · pp. 31–37 Read article
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Evaluation of Antipyretic Activity of Olax Scandens (Roxb.) Stem Bark
Abstract: Abstract:Traditionally, the decoction of Olax scandens (Roxb.) stem bark is used to cure fever and cough. The present experimental study was carried out to evaluate the antipyretic activity of stem bark of Olax scandens (Roxb.) on experimental animals. Brewer’s yeast was used as a pyrogen in Wistar strain albino rats for inducing pyrexia. The stem bark powder, at a dose of 540 mg/kg body weight of rat was suspended in …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 5, Issue 1, 2015 · pp. 15–18 Read article
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An Open Label Randomized Comparative Clinical Study of Safoof-e-Mohazzil versus Atorvastatin in the Cases of Fart-e-Tadassum-Fid-Dam (Primary Hyperlipidaemia)
Abstract: Hyperlipidaemia (Fart-e-Tadassum-Fid-Dam) is a common metabolic disease seen in clinical practice. It is mentioned that increased lipid level is associated with the pathogenesis of atherosclerosis. Theory of hyperlipidaemia meets similarly on the basis of etiology, presentation, complications, patho-physiology and non-pharmacological management with Saman-e-mufrit (obesity). Therefore, it is an important need to provide safe and effective drug from Unani system of medicine for the long term management of hyperlipidaemia. In the …
Published in Research & Reviews : A Journal of Unani, Siddha and Homeopathy · Vol. 5, Issue 1, 2018 · pp. 6–12 Read article
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Bergenin: Review of The Methods of Determination and Quantification
Abstract: Studies have shown that Bergenin has various pharmacological functions, such as Anti-lithiatic, Anti-oxidant, anti-inflammatory, Anti-bacterial, Anti-viral, Anti-cancer, Anti-cholinesterase, Anti-diabetic, Hypolipidemic, Anti-tussive, Hepatoprotective and Immunomodulatory. Bergenin is found in the Saxifragaceae, Euphorbiaceae, Myrsinaceae, Dipterocarpaceae, and Fabaceae genera and a range of beneficial effects on human health. The number of bioactive compounds in various bergenia species must be determined in order to achieve the best quality raw material for herbal preparations. As …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 8, Issue 2, 2023 · pp. 52–66 Read article
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A Systemic Review: Pithecellobium dulce (Jangal Jalebi)
Abstract: Pithecellobium dulce (Roxb.) Benth., commonly referred to as Jangal Jalebi, Vilayati Babul, or Manila Tamarind, is a versatile tree in the Leguminosae (Fabaceae) family. It is commonly found in tropical and subtropical areas and is valued for its ecological, medicinal, and nutritional benefits. The plant is rich in a variety of bioactive compounds, including flavonoids, alkaloids, phenols, glycosides, tannins, saponins, terpenoids, and steroids, which enhance its pharmacological potential. Different extracts …
Published in Research & Reviews : Journal of Herbal Science · Vol. 15, Issue 1, 2026 · pp. 14–20 Read article
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A Review on Psidium Guajava
Abstract: Psidium guajava is an evergreen shrub belongs to Myrtaceae family and commonly known as guava. It contains phenolic compounds and acts as anti-oxidant properties as well as immunostimulant. It has a higher number of vitamins and minerals. Every part of this plant contains various phytochemicals like quercetin, rutin, kaempferol, gallic acid, epicatechin, ursolic acid, glucosides, guavanoic acid, guava coumaric acid, saponins, terpenoids are present. It shows various pharmacological activities like …
Published in Research and Reviews : Journal of Crop science and Technology · Vol. 10, Issue 3, 2021 · pp. 9–14 Read article
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The Review of Beetroot Composition and Benefits of Beetroot
Abstract: The genus Beta L. comprises the red beetroot, which is linked to the Betoideae branch of the goosefoot family (Amaranthaceae). Because the tuberous root of the vegetable beetroot (Beta vulgaris L.) contains a large amount of nutrients, including vitamins and minerals as well as substances with physiological activity, including betalain, inorganic nitrates, polyphenols, and folates, it is consumed in every country around the world. Like its relative turnip, the beet …
Published in Research and Reviews : A Journal of Ayurvedic Science, Yoga and Naturopathy · Vol. 12, Issue 3, 2025 · pp. 35–42 Read article
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A Critical Appraisal on Phytochemical Constituents and Therapeutic Effect of Yashtimadhu (Glycyrrhiza glabra)
Abstract: In present era, traditional medicines are getting more attention worldwide. Herbal medicines are one among them with great therapeutic significance and potential actions. Glycyrrhiza glabra is one of the important and widely used classical herbal medicinal plants with vast clinical action. Glycyrrhiza glabra Linn. Commonly known as Liquorice, sweet wood, Mulahatti and Yashtimadhu. It has key activities from getting rid of simple cough, eye troubles to curing asthma, bronchitis, abdominal …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 6, Issue 3, 2017 · pp. 6–10 Read article
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Assessment of Malaria Prevalence and Evaluation of Therapeutic Efficacy of Artemether/Lumefantrine (Coartem®) against Uncomplicated Falciparum Malaria in Wondogenet Woreda, SNNPR, Ethiopia
Abstract: Normal 0 false false false EN-US X-NONE X-NONE AbstractThe study was conducted to assess malaria prevalence and to evaluate therapeutic efficacy of Coartem® for the treatment of uncomplicated falciparum malaria in Wondogenet Woreda, Sidama Zone, Ethiopia. Since the spread of Plasmodium falciparum, parasite resistance to almost all antimalarial monotherapies is a serious impediment to malaria control. Artemether-lumefantrine (Coartem®) therapy has been in use as the first-line treatment for uncomplicated falciparum …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 5, Issue 2, 2015 · pp. 26–34 Read article
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A Study and Report on the Role of Clinical Pharmacy Services Provided by the Doctor of Pharmacy in the Management of Thyroid Disorders (Hyperthyroidism and Hypothyroidism) to a Tertiary Care Hospital
Abstract: Thyroid hormones affect the function of virtually every organ system. In children, thyroid hormone is critical for normal growth and development but in adults, the main role of these thyroid hormones is to maintain stability. The main thyroid hormones which play such an important are the Thyroxine (T4) and Triiodothyronine (T3) hormones. Hence, Thyroid disorders encompass a variety of disease states affecting thyroid hormone production or secretion that result in …
Published in Trends in Drug Delivery · Vol. 8, Issue 2, 2023 · pp. 25–38 Read article
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Adverse Drug Reactions Monitoring by Healthcare Professionals in Noida, Uttar Pradesh Region—A Study on Knowledge, Attitude and Method of Application
Abstract: The study was aimed to assessing the knowledge, attitude and method of application towards adverse drug reactions reporting by the doctors and other healthcare professionals (HCPs) in Delhi-NCR (Noida region), to get an insight into the causes of under-reporting of adverse drug reactions (ADRs) and to suggest possible ways of improving this method of reporting. A structured validated questionnaire was used consisting of 10 questions divided into three components; awareness, …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 7, Issue 3, 2017 · pp. 1–6 Read article
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Comparative Study of Bioactive Phytochemicals from Hexane Extract of Two Amaranthaceae Leafy Vegetables by GC-MS Method
Abstract: Amaranthus tricolor Linn and Amaranthus viridis Linn, belonging to the Amaranthaceae family, are popularly consumed leafy vegetables in India and many other countries globally. The bioactive components of Hexane extract from these two plants have been analysed using gas chromatography-mass spectrometry (GC–MS) technique. According to analysis, both species contain a total of nineteen important chemicals. Of these, ten were found in A. tricolour L. and nine in A. viridis L. …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 7–17 Read article