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1940 articles for “significant” (ranking capped at the first 2,000 matches — narrow the search to see the rest)
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Screening of Pharmaceutically Significant Methioninase-Producing Fungi from the Satpura Range of Hoshangabad District and Its Large-Scale Production
Abstract: L-methioninase, an enzyme with notable anticancer properties, has emerged as a promising therapeutic agent due to its ability to selectively degrade methionine, a critical amino acid for the survival of methionine-dependent cancer cells. Methionine dependency, observed in many tumor cells, is a metabolic vulnerability that can be exploited for targeted cancer therapy. The Satpura Range in the Narmadapuram District, India, with its diverse microbial ecosystems, offers a rich reservoir for …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 12, Issue 2, 2025 · pp. 33–43 Read article
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Bedaquiline: An In-Depth Exploration into Its Antitubercular Significance
Abstract: Tuberculosis is still a leading infectious disease and a major threat to public health. Although there has been a slow decrease in the incidence over years, its “hard to kill nature” is responsible of about 2 million deaths in HIV infected individuals annually. Bedaquiline, a Diaryl-Quinoline drug was fast-track approved as an orphan drug to combat drug resistance. It shows potent activity against Mycobacterium tuberculosis by interfering with the production …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 12, Issue 2, 2025 · pp. 06–14 Read article
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Significance of Physical Activities for Mental and Physical Health
Abstract: Physical activity is essential for maintaining both mental and physical health, providing wide-ranging benefits that enhance quality of life at all ages. Regular exercise, such as walking, cycling, swimming, or yoga, strengthens the cardiovascular system, boosts muscle and bone health, and improves metabolic function, which in turn reduces the risk of chronic conditions like diabetes, hypertension, and obesity. Beyond these visible benefits, consistent physical activity enhances flexibility, balance, and endurance, …
Published in Recent Trends in Sports · Vol. 3, Issue 1, 2026 · pp. 1–6 Read article
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Significance and Analysis of the Time and Cost Overrun in the Construction Industry of Mumbai
Abstract: The occurrence of time and cost overrun has become quite significant in a majority of construction projects in India, which is negatively affecting the GDP and potential development of nation. As per the statistics of project cost and duration in March 2012, 179 projects out of 555 projects of worth 150 Crore INR have been facing cost and time overrun and others are at the very high risk, with the …
Published in Journal of Industrial Safety Engineering · Vol. 8, Issue 2, 2021 · pp. 7–13 Read article
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Ameliorating Surface Roughness and Tensile Strength of ASA Fabricated Parts by Analyzing Significant FDM Printing Parameters Using Response Surface Methodology
Abstract: The constantly growing demand for acrylonitrile styrene acrylate (ASA) polymer in the automotive market to its use for fabricating different components such as dashboards, the interior, lights, and electrical components challenges manufacturers to continuously optimize its mechanical properties to meet consumer demand. Despite the widespread availability of three-dimensional (3D) printing techniques, research on the most efficient and cost-effective methods of producing ASA-printed components is still indispensable. Therefore, the purpose of …
Published in Journal of Polymer & Composites · Vol. 11, Issue 3, 2023 · pp. 1–12 Read article
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Review on Significance of IoT (Internet of Things)
Abstract: Abstract: IoT is a kind of “Universal global neural network” which connects different things easily. IoT is prudentially connected devices and systems which comprised of smart machines interacting and communicating with other machines, environments, pipeline structure and sensor network technologies will rise to meet this new challenge. Due to which, a huge amount of data are produced, stored and data is then processed into useful actions, that can live much …
Published in Recent Trends in Electronics Communication Systems · Vol. 6, Issue 1, 2019 · pp. 8–15 Read article
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The Significance of an Open and Fair Internet
Abstract: This review work investigates the idea of net neutrality, highlighting its importance, arguing for and against it, and examining its effects on society. According to the concept of "net neutrality", all internet traffic should be treated equally without prejudice or favouring any one data or service over another. The study chronicles the development of net neutrality from its early years, when academic research was the main use of the internet, …
Published in Journal Of Network security · Vol. 11, Issue 1, 2023 · pp. 39–43 Read article
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A Conceptual Study of Physiological and Clinical Significance of Nidra with Sleep
Abstract: Ayurveda is the science of life and its main aim is to maintain healthy status of healthy living being, i.e. prevention of disease and treatment of disease. In order to prevent the unmanifested diseases and to cure the manifested ones, an individual’s desire of happiness should follow the regimen prescribed in text of Ayurveda. As per Ayurvedic science, nidra is one among most essential factors responsible for a healthy life. …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 7, Issue 3, 2018 · pp. 6–10 Read article
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A Conceptual Study of Function of Ojas w.s.r. to Vyadhikshamatva and its Clinical Significance
Abstract: Ayurveda is the science of life and its main aim is to maintain healthy status of healthy living being, i.e., prevention of disease and treatment of disease. To fulfill these purposes, Ayurveda has mentioned various fundamental principle in reference of Sharir Rachna, Sharir kriya, Chikitsa, etc. Concept of oja and vyadhikshamatva explained in Ayurvedic texts is one among them. Though located in hrdaya, ojas pervades all over the body and …
Published in Research and Reviews : A Journal of Ayurvedic Science, Yoga and Naturopathy · Vol. 5, Issue 3, 2018 · pp. 24–29 Read article
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Significance of Classical Unani Tadabeer (Regimes) in the Preparedness of Pandemic Dilemma COVID-19
Abstract: Unani system of medicine focuses on the holistic well-being of the individual and community. It comprises of the four modes of treatments/managements. These are the (ilaj bil ghiza) dietotherapy, ilaj bil Tadabeer (Regimental therapy), ilaj bil dawa (pharmacotherapy) and ilaj bil yad (surgery). Among these four modes, one of the most affordable and reliable and result-oriented is the ilaj bil Tadabeer. Various therapies and regimens are the core components of …
Published in Research and Reviews: A Journal of Health Professions · Vol. 11, Issue 2, 2021 · pp. 12–14 Read article
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Production and Characterization of Cardanol Based Schiff Complexes and their Biological Significance
Abstract: Synthesis and analysis of cardanol consisted Schiff base ligand along with its complexes such as Cu, Co and Ni are considered as a novel tetradentate cardanol contained Schiff base ligand molecules for various biological effects. It is prepared by the condensation reaction of 2-aminophenol and di-α formylmethoxybis (3-pentadecenyl phenyl) methane which is termed as DFMPM in the molar ratio of 2:1. The characterization of the experimental compounds is done with …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 9, Issue 2, 2019 · pp. 19–24 Read article
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Significant Role of the Handloom Industry for the Marginal Category: A Case Study on Purba Medinipore
Abstract: AbstractWith the advancement of science and technology, the idea of small-scale industry has changed greatly. More emphasis has been given on agriculture as well as small-scale industry. Handloom is such type of industry, which begins with cultivation of cotton plant and ultimately ends up with spinning and making of cotton cloths. The handloom industry runs throughout the year. It has an additional advantage of providing employment to agriculturists even during …
Published in E-Commerce for Future & Trends · Vol. 3, Issue 3, 2016 · pp. 22–24 Read article
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A Disquisition on Artificial intelligence: and its significance in ME-BAD
Abstract: Artificial intelligence (AI) is software which is designed such a way that it can react as humans with natural intelligence (NI) and which can lessen the human work load. AI is a kind of a software or application which is developed for making decisions, resolving problems in real-time. Designing a model for the systems which must have a ability to recall things as human being and knowing the criterion, and …
Published in Journal of Artificial Intelligence Research & Advances · Vol. 5, Issue 2, 2018 · pp. 51–57 Read article
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Navigating the Command Line: Unveiling the Significance of Shell Commands and Simple Programming in Modern Computing
Abstract: Shell commands are fundamental tools for interacting with operating systems and executing various tasks efficiently. This research article delves into the crucial significance of shell commands and basic programming in today’s computing environments. It delves into the foundational concepts that make command-line interfaces and scripting crucial components of modern computing. The study highlights the efficiency, flexibility, and automation capabilities offered by shell commands and programming scripts through real-world examples demonstrating …
Published in Journal of Advances in Shell Programming · Vol. 10, Issue 3, 2023 · pp. 1–8 Read article
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A Review on the Clinical and Pathological Significance of Prorenin Receptor [(P)RR]
Abstract: The (pro)renin receptor (P)RR discovery, which is a novel constituent of Renin Angiotensin-Aldosteron System (RAS) has brought renin and (pro)renin back into spotlight. The (P)RR binds both renin and its inactive precursor (pro)renin, this binding triggers a cascade of intracellular signalling that eventually leads to upregulation of the expression of profibrotic genes, potentially leading to pathogenesis of cardiac and renal fibrosis, growth and remodelling. Clinically, it is also seen that …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 5, Issue 2, 2015 · pp. 11–17 Read article
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Significance of TE Domain and Genetic Variations in FASN Gene in Dairy Animals
Abstract: The interest in the bovine fatty acid synthase (FASN) gene has increased during the last few years. FASN is a multifunctional enzyme that catalyzes de novo biosynthesis of long-chain saturated fatty acid, and alteration of this enzyme may affect economic traits including fatty acid composition. FASN is involved in fat metabolism and is an important candidate gene affecting fat composition of milk because of its central role in de-novo lipogenesis …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 6, Issue 3, 2016 · pp. 33–38 Read article
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UAVs (Unmanned Aerial Vehicle): Working and Significance
Abstract: In this article new advances technology is being introduced in the field of aerospace Engineering such as Unmanned air Vehicles (UAVs). Their basic idea of working principle is discussed with multiple uses in many industries for different purpose. A descriptive review is provided on the working, concept and future aspects of this advance technology. The different significance is discussed in multiple industries. The Article is providing a concept for better …
Published in Journal of Aerospace Engineering & Technology · Vol. 11, Issue 3, 2021 · pp. 33–38 Read article
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Genetic Variability and Significance of STAT Gene in Dairy Animals
Abstract: Abstract Importance in the bovine signal transducer and activator of transcription (STAT) gene has increased due to involvement of STAT1 in the development of the mammary gland and regulating the transcription of genes involved in milk protein synthesis and fat metabolism in lactating dairy animals. Signal transducer and activator of transcription gene are a family of cytoplasmic proteins that are stimulated in response to a large number of growth factors, …
Published in Research and Reviews : Journal of Dairy Science and Technology · Vol. 5, Issue 3, 2016 · pp. 1–6 Read article
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Significance of Growth Rate, Acceptability of Fermented Milk and Release of Peptides by Lactic Cultures
Abstract: Ten lactic cultures (S. thermophilus MD2, S. thermophilus MD8, Lc. lactis 009, L. fermentum AI2, L. fermentum AI3, L. fermentum 138, L. plantarum AD29, L. rhamnosus NS4, L. rhamnosus NS6 and E. feacalis ND3) isolated from vegetables and fermented foods were evaluated for their potential to ferment milk, produce good quality curd and ability to release peptides in fermented milk. It was found that S. thermophilus MD8, S. thermophilus MD2 …
Published in Research and Reviews : Journal of Dairy Science and Technology · Vol. 5, Issue 1, 2016 · pp. 31–40 Read article
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Significance of Butyrophilin Gene in Relation to Milk Constituents in Dairy Animals
Abstract: Abstract Butyrophilin (BTN1A1) has been classified as member of transmembrane proteins of immunoglobulin family. BTN1A1 is a QTL candidate gene having role in milk production and composition (fat) in dairy animals. The gene product BTN1A1 has function during secretion of milk fat and its expression is tissue specific in lactating mammary tissue. Butyrophilin gene constitutes of a more than 40% by weight of total protein and synthesized as a peptide …
Published in Research and Reviews : Journal of Dairy Science and Technology · Vol. 6, Issue 1, 2017 · pp. 24–30 Read article