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165 articles for “public health challenges”
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The Evolution of Asthma Management: A Comprehensive Analysis of GINA 2024 Guidelines, Endotype-Driven Diagnosis, and Targeted Biologic Intervention
Abstract: Asthma remains a substantial global public health challenge, characterized by heterogeneous airway inflammation leading to variable airflow obstruction. Recent advances in personalized medicine and guideline revisions, notably the Global Initiative for Asthma (GINA) 2024 update, mandate a profound paradigm shift from reliance on short-acting beta2-agonists (SABA) to antiinflammatory reliever (AIR) strategies utilizing inhaled corticosteroid (ICS)-formoterol. This report provides an exhaustive analysis of current asthma epidemiology, molecular pathogenesis distinguishing between Type …
Published in Recent Trends in Infectious Diseases · Vol. 3, Issue 2, 2026 Read article
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Managing Chronic Diseases: Diabetes Mellitus
Abstract: Diabetes mellitus is one of the most prevalent chronic non-communicable diseases worldwide and represents a major public health challenge due to its long-term complications, increasing prevalence, and economic burden on individuals and healthcare systems. It is distinguished by chronic hyperglycemia brought on by deficiencies in either insulin action or secretion, or both. Diabetes causes increasing harm to several organ systems, including the kidneys, eyes, neurological system, and cardiovascular system, if …
Published in International Journal of Antibiotics · Vol. 3, Issue 2, 2026 Read article
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Cardiovascular Illness Detection and Categorization with Innovative Neural Networks
Abstract: Health-related problems are increasingly prevalent in modern-day societies and are significantly shaped by a multitude of factors encountered in everyday life. Among these, cardiovascular diseases have emerged as one of the primary causes of death on a global scale, posing serious challenges to public health systems. In response to this growing concern, the present study proposes a machine learning-based framework that is not only highly effective but also reliable and …
Published in Journal of Artificial Intelligence Research & Advances · Vol. 12, Issue 2, 2025 · pp. 21–30 Read article
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AI- based Prediction of Misinformation Virality Before Wide Dissemination using Attention-based Multi-modal
Abstract: Misinformation on social media has emerged as a critical global challenge, impacting public health, democratic institutions, and societal trust. While existing research has largely concentrated on detecting misinformation after it begins circulating, predicting its virality before wide dissemination remains an underexplored area, limited work addresses predicting its virality before wide dissemination. This paper presents a conceptual framework using attention-based multi-modal deep learning models to estimate the virality of misinformation posts …
Published in Journal of Mobile Computing, Communications & Mobile Networks · Vol. 12, Issue 3, 2025 Read article
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Investigating the Impact of Viral Infections on Pharmacokinetics and Pharmacodynamics of Antiviral Drugs
Abstract: The emergence and re-emergence of viral infections pose significant challenges to public health, necessitating a comprehensive understanding of how these infections impact the pharmacokinetics and pharmacodynamics of antiviral drugs. This review explores the intricate interactions between viral pathophysiology and the pharmacological effects of antiviral agents. Factors such as viral replication dynamics, host immune responses, and the genetic variability of both viruses and hosts significantly influence drug absorption, distribution, metabolism, and …
Published in International Journal of Virus Studies · Vol. 1, Issue 2, 2024 · pp. 23–30 Read article
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Toward Comprehensive Immunization: The Role of Combined COVID-19 and Influenza Vaccines in Public Health
Abstract: The emergence of multi-pathogen vaccines, particularly those combining protection against COVID- 19 and influenza, marks a significant advancement in immunization efforts. These combination vaccines have the potential to streamline vaccination processes, improve vaccine uptake, and reduce the burden on healthcare systems by offering a single dose that targets both viruses. COVID-19 and seasonal influenza are major public health concerns, with overlapping symptoms and seasonal patterns that justify the rationale for …
Published in International Journal of Vaccines · Vol. 2, Issue 1, 2025 · pp. 9–17 Read article
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Zika Virus: Long-term Effects and Vaccine Development Efforts
Abstract: Zika virus (ZIKV) is a mosquito-borne flavivirus that gained international concern following the 2015-2016 outbreak in the Americas. Although most ZIKV infections are asymptomatic or mild, the virus presents significant public health risks due to its ability to cause severe neurological complications, especially in pregnant women and their offspring.Congenital Zika Syndrome (CZS) encompasses a range of fetal abnormalities, including microcephaly, vision impairment, hearing loss, and developmental delays. Infants exposed to …
Published in International Journal of Virus Studies · Vol. 2, Issue 1, 2025 · pp. 25–28 Read article
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Pharmacovigilance and drug safety current trends and challenges
Abstract: Pharmacovigilance and drug safety are critical areas of focus in healthcare, aimed at monitoring the safety and efficacy of pharmaceutical products throughout their lifecycle. This review explores current trends, emerging technologies, and challenges in pharmacovigilance, emphasizing their impact on public health and regulatory practices. With the increasing complexity of global pharmaceutical markets, pharmacovigilance systems are evolving to integrate real-time data analytics, artificial intelligence (AI), and machine learning (ML) to detect …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 12, Issue 1, 2025 · pp. 19–27 Read article
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Tsetse Flies and African Trypanosomiasis: Biology, Epidemiology, and Integrated Vector Control.
Abstract: Tsetse flies (Glossina spp.) are hematophagous dipterans confined to sub-Saharan Africa and serve as cyclical vectors of human African trypanosomiasis (HAT) and African animal trypanosomiasis (AAT), with major implications for human health, livestock productivity, and rural development. An integrated understanding of tsetse biology, parasite transmission, climate, and land–use–driven distribution shifts, and the comparative performance of control tools—especially insecticides and sterile insect technique (SIT)—is essential for designing sustainable elimination strategies. HAT …
Published in International Journal of Insects · Vol. 3, Issue 1, 2026 · pp. 21–28 Read article
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Unveiling the Silent Threat: The Escalation and Defence Against Antibiotic Resistance
Abstract: The global challenge of antibiotic resistance presents a significant risk to public health, driven by multifaceted factors worldwide. This issue, akin to the impacts of climate change, requires concerted efforts at national and international levels to mitigate its consequences. Antibiotics have revolutionized modern medicine, enabling critical interventions like surgeries, transplants, and cancer treatments. However, without global collaboration, we face significant setbacks across medical, social, and economic domains. Initiatives to address …
Published in International Journal of Antibiotics · Vol. 2, Issue 2, 2025 · pp. 1–26 Read article
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Study of Social Trends Prediction Using AI
Abstract: AI (Artificial Intelligence) has fundamentally changed the ability to analyze social trends by using large datasets to develop predictions about human behavior, public sentiment, and global events. Using methodologies such as Natural Language Processing (NLP), Time-Series Forecasting, and Graph-Based Social Network Analysis, AI is able to find hidden correlations in a variety of available datasets, from social media to economic indicators to public records, and fundamentally changes decision-making based on …
Published in Journal of Artificial Intelligence Research & Advances · Vol. 12, Issue 3, 2025 · pp. 19–29 Read article
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Artificial Intelligence in Microbiological Research: Methods, Applications and Implications
Abstract: Artificial Intelligence (AI) is revolutionising microbiological research by enabling the rapid analysis of complex biological data and improving the accuracy, efficiency, and reliability of scientific investigations. Recent advances in machine learning, deep learning, and bioinformatics have transformed AI into a powerful tool for studying microorganisms, their genetic composition, evolutionary patterns, and interactions with hosts and the environment. AI-driven computational models can process large and complex datasets far more efficiently than …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 16, Issue 2, 2026 Read article
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Vaccines in the Fight Against COVID-19: Mechanisms, Efficacy, and Global Challenges
Abstract: The SARS-CoV-2 pandemic has created an unparalleled public health problem, necessitating comprehensive prevention. This page discusses COVID-19's evolution, scientific understanding, and quick vaccine production and implementation. It compares the mechanisms, efficacy, and safety profiles of the four major types of COVID-19 vaccines—namely mRNA, viral vector, protein subunit, and inactivated virus vaccines. Each type is evaluated in terms of how it stimulates the immune response, its effectiveness in preventing infection or …
Published in Recent Trends in Infectious Diseases · Vol. 2, Issue 2, 2025 · pp. 34–48 Read article
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Advancing Public Health Through Vaccination: A Narrative Review of Respiratory Syncytial Virus (RSV) Immunization Strategies
Abstract: RSV is a significant factor in causing lower respiratory tract infections in children, especially among infants and toddlers. Different age groups are affected by RSV in distinct ways, specifically affecting young children and elderly. People who are immunocompromised are more susceptible to RSV. Centres for Disease Control and Prevention has recommended vaccination doses with the age group to prevent mortality associated with RSV. Signs and symptoms often resemble common cold …
Published in Research and Reviews : A Journal of Immunology · Vol. 14, Issue 1, 2024 · pp. 1–6 Read article
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Climate Change and the Spread of Pathogens: Implications for Public Health
Abstract: Climate change plays a significant role in the spread of infectious diseases by shifting how pathogens behave, affecting how vulnerable hosts are, and changing the way diseases are transmitted.Rising global temperatures, changing precipitation levels, and extreme weather events are accelerating the spread of bacteria, viruses, fungi, and parasites, increasing the risk of outbreaks worldwide. Warmer conditions favor the survival and expansion of vector-borne diseases such as malaria, dengue, and Zika …
Published in International Journal of Pathogens · Vol. 2, Issue 1, 2025 · pp. 1–5 Read article
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Health and Air Quality in High-Density Neighbourhoods of Delhi
Abstract: Delhi, one of the fastest-growing megacities in the world, continues to grapple with critical challenges of urban air pollution and its direct consequences on public health. High-density neighborhoods like Karol Bagh, Lajpat Nagar, Chandni Chowk, and East Delhi face disproportionately higher exposure to degraded air quality due to compact urban forms, overcrowding, mixed land use, and heavy traffic. This paper explores the interrelationship between air quality and health outcomes, emphasizing …
Published in International Journal of Environmental Planning and Development Architecture · Vol. 3, Issue 2, 2025 · pp. 26–32 Read article
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Anti-hyperglycemia Effects of Plant Secondary Metabolites Towards PKA/CREB Pathway Activation in Diabesity
Abstract: Objective: Diabesity, the amalgamation of diabetes and obesity, presents a significant global health challenge. This research carefully examines how plant secondary metabolites influence glucose regulation in diabetes using the PKA/CREB pathway, paying particular attention to diabesity—the combination of diabetes and obesity. Understanding the complex ways in which these metabolites affect metabolic health will help to identify new treatment approaches for managing diabetes and its associated problems. By conducting a thorough …
Published in International Journal of Biochemistry and Biomolecule Research · Vol. 2, Issue 1, 2024 · pp. 33–50 Read article
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Review of Current Trends in Vaccine Development against Zoonotic Viruses: Challenges and Innovations
Abstract: The emergence of zoonotic viruses poses a significant threat to global public health, necessitating rapid advancements in vaccine development. This review highlights the current trends and innovative strategies employed in the creation of vaccines against zoonotic pathogens, including but not limited to viruses responsible for diseases such as Ebola, Zika, Nipah, and more recently, SARS-CoV-2. We discuss various vaccine platforms, including inactivated, live attenuated, mRNA, and viral vector vaccines, focusing …
Published in International Journal of Virus Studies · Vol. 1, Issue 2, 2024 · pp. 1–11 Read article
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Tobacco Use Among Government and Public School Students in the Sangam Vihar Area of South Delhi
Abstract: The most fundamental right inherent to all human beings, as recognized in international law, is the right to health. Men and women worldwide prioritize good health as their top aspiration when asked to rank their desires. Currently, one of the most significant global challenges to achieving this desire is the widespread epidemic of tobacco use. This exceptional epidemic is notable not just for its magnitude but also for its characteristics. …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 14, Issue 1, 2024 · pp. 1–5 Read article
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Assessing the Increasing Incidence of Prostate Cancer in Urban Delhi: Risk Factors, Early Detection, and Treatment Challenges
Abstract: Background: Prostate cancer has emerged as the second most prevalent cancer among men in India, with rapidly increasing incidence rates in urban areas like Delhi. This rise is attributed to urbanization, lifestyle changes (high-fat diets, tobacco use, sedentary behavior), increased life expectancy, and improved diagnostics. Despite its growing burden, low awareness, limited screening programs, and treatment barriers hinder early detection and effective management. This study examines the epidemiological trends, risk …
Published in International Journal of Oncological Nursing and Practices · Vol. 3, Issue 2, 2025 · pp. 21–28 Read article