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22 articles for “long-term risk prediction”
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Comparative Efficacy and Safety of Safinamide and Rasagiline in the Treatment of Parkinson’s Disease: A Meta-Analysis and Systematic Review
Abstract: Background: Recent studies have suggested Rasagiline and Safinamide monotherapy as potential management options for Parkinson’s disease. Parkinson’s disease, a neurological disorder characterized by tremors and movement difficulties, necessitates treatments aimed at managing clinical symptoms. Levodopa remains the primary effective treatment for Parkinson’s disease symptoms; however, its long-term use often leads to motor complications in many patients. Additional therapeutic drugs, such as dopamine agonists and monoamine oxidase B inhibitors, including Safinamide …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 14, Issue 3, 2024 · pp. 74–91 Read article
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Quantitative Image-Based Assessment of Degradation Patterns in Polymer-Based Medical Implants
Abstract: Polymer-based medical devices are widely used in clinical practice, where long-term material degradation can compromise performance and patient safety. Traditional polymer degradation studies predominantly rely on laboratory-based experiments, which often fail to capture real-world operational and usage conditions. In this study, a multimodal, data-driven framework is proposed for the quantitative assessment of degradation patterns in polymer-based medical devices using publicly available clinical failure data. Structured operational parameters, including cumulative usage …
Published in Journal of Polymer & Composites · Vol. 14, Issue 2, 2026 · pp. 1510–1518 Read article