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150 articles for “immunological”
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Early Life Nutrition as a Determinant of Long-Term Vaccine Immunogenicity in Livestock: Mechanisms, Practical Strategies, and Species-Specific Considerations
Abstract: Early life represents a critical period for immune system development in livestock, during which nutritional exposures can exert long lasting effects on vaccine immunogenicity. Although vaccination is a cornerstone of infectious disease control in food producing animals, marked variability in vaccine induced immune responses is frequently observed under commercial conditions. Growing evidence suggests that this variability is partly driven by differences in early nutritional status, which can influence immune maturation, …
Published in International Journal of Vaccines · Vol. 3, Issue 1, 2026 · pp. 15–26 Read article
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Toxicological Profiling and Safety Assessment of NASAT 2.0: A Conceptual Framework for Adaptive Nanoparticle Therapy in Rabies
Abstract: Rabies, caused by the highly neurotropic Rabies lyssavirus, remains one of the most enigmatic and universally lethal infectious diseases known to modern medicine. Once clinical symptoms manifest following successful neuroinvasion, the fatality rate approaches absolute certainty (approximately 99.9%), a staggering statistic that has remained largely unchallenged despite massive, concurrent advances in modern virology, critical care medicine, and cellular immunology. Current late-stage therapeutic protocols, most notably the widely debated Milwaukee Protocol, …
Published in Research and Reviews: A Journal of Toxicology · Vol. 16, Issue 2, 2026 · pp. 1–19 Read article
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Recent Advancement in Understanding the Aetiopathogenesis of Psoriasis: A Review
Abstract: Psoriasis is an immune-mediated inflammatory skin disease with periods of recurrence and remission. Various researches have globally explored the aetiopathogenesis of psoriasis but still it is not crystal clear. Abundant evidence suggest that dysregulation of immune cells in the skin, particularly keratinocytes, T cells, dendritic cells, natural killer cells, neutrophils, and macrophages play a vital role in the development of psoriasis. The combined effects of these cells explain most of …
Published in Research and Reviews : A Journal of Immunology · Vol. 7, Issue 2, 2017 · pp. 9–21 Read article
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Mucosal Vaccines in Fish: Novel Advances in Technology and Delivery: A Review
Abstract: Vaccines rely on the acquired immune system and prime an animal to a particular antigen so that on subsequent encounter; it is recognized and quickly destroyed. The vast majority of pathogens enter the body via the mucosal surfaces of the gastrointestinal, respiratory, and urogenital tracts, where they initiate mucosal infections that lead to systemic infections. There is strong evidence that an optimum mucosal immune response can prevent systemic infection and …
Published in Research and Reviews : A Journal of Immunology · Vol. 9, Issue 1, 2019 · pp. 14–26 Read article
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Griscelli Syndrome Type 2: A Case Report on Its Diagnosis and Management
Abstract: Griscelli syndrome (GS) is an autosomal recessive disorder which is very rare and is characterized by dilution of pigments and variable immunodeficiency. Researchers have identified three types of this disorder which are distinguished by their genetic cause and pattern of signs and symptoms: Type 1, Type 2 and Type 3, caused by the mutation of MYO5A, RAB27A and MLPH genes respectively. Subtype 2 being the most common, is characterized by …
Published in Research and Reviews : A Journal of Immunology · Vol. 8, Issue 2, 2018 · pp. 5–7 Read article
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Progress from the Traditional Vaccines to Novel Rational Vaccine Designs
Abstract: Vaccines are among the most valuable assets for saving human and animal lives. The vaccines discovered and designed on the Pasteurian principles laid the foundations of the traditional vaccine regime during the late-19th century. Some traditional vaccine designs proved remarkably successful, while others had safety or efficacy problems, and still others failed- particularly those against diseases caused by non-cultivable, hyper-variable or opportunist pathogens, or those requiring cellular immunity. The problems …
Published in Research and Reviews : A Journal of Immunology · Vol. 6, Issue 3, 2016 · pp. 17–31 Read article
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Canine Ehrlichiosis and Its Diagnostic Techniques: Review
Abstract: Canine monocytic ehrlichiosis, caused by Ehrlichia canis is one of the important immuno-suppressive infectious vector-borne diseases of dogs. Importantly, canine ehrlichiosis can be caused by different Ehrlichia species, which are intracellular rickettsial organisms belonging to the order Rickettsiales and included in the family Rickettsiaceae. Ehrlichias are the obligate intracellular organisms that affects the host immunologic response. It is typically a disease of leukocyte and platelet manifested by an acute reduction …
Published in Research and Reviews : A Journal of Immunology · Vol. 10, Issue 1, 2020 · pp. 1–11 Read article
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Tuberculosis Epidemiology and its Diagnostic Modality
Abstract: Tuberculosis (TB) remains a global health emergency, with India being the epicenter, recording 2.23 million cases and approximately 4.53 lakhs deaths in 2021. Despite efforts by the National Tuberculosis Eradication Program (NTEP), the anticipated decrease in the incidence and prevalence of TB has not been actualized. This paper examines the persistently high rates of TB in India, identifying critical risk factors such as male gender, marital status, overcrowding, socioeconomic disadvantages, …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 13, Issue 3, 2023 · pp. 7–11 Read article
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Animal Gastrointestinal Tract in Animals Health
Abstract: The gastrointestinal tract's (GIT) functionality and health are essential elements that influence animal productivity. Since the management of GIT growth and health involves numerous complicated systems, it is critical to have a better understanding of these interconnections in order to create strategies for modulating GIT functioning and health in the perspective of better animal performance. Within in the animal scientific community, this term of "gut health" has sparked considerable interest. …
Published in International Journal of Animal Biotechnology and Applications Read article
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Using of Rat Model Over Other Species: A Review
Abstract: The first domesticated morphological features to be used in studies were rats. Scientists employed the brown rat Rattus norvegicus to study human biology and therapeutics two decades ago, focusing on the consequences of hunger and oxygen deprivation. Rats have been used to answer a wide range of basic science problems relevant to common human ailments in the fields of pharmacology, immunology, physiology, nutrition, behaviour, learning, and toxicity. The article gives …
Published in International Journal of Animal Biotechnology and Applications Read article
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The Impact of Dietary Components on Lactation: A Critical Review
Abstract: Infant growth and well-being depend on an adequate and species-specific amount of nutrients, antibodies, and immunological components, which are provided by human breastfeeding, the cornerstone of newborn sustenance and development However, some moms struggle with producing inadequate milk, which can put the health advantages of nursing for both mother and child in jeopardy and cause stress, anxiety, and perhaps early weaning. This review discusses the fascinating idea that food changes …
Published in International Journal of Nutritions · Vol. 1, Issue 1, 2024 · pp. 31–36 Read article
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Alopecia Areata: Complex Roots and Potential Cures
Abstract: Autoimmunity is when the healthy organs of an individual’s body are attacked by its own immune system, leading to illness or functional abnormalities. The hair follicles (HFs) are wrongly destroyed by the immune system in a condition known as Alopecia Areata and results in chronic non-cicatricial hair loss discernible by spherical patches. It’s a severely worsening or relapsing malady that can be permanent during severe falling out of hair. In …
Published in International Journal of Vaccines · Vol. 1, Issue 1, 2024 · pp. 41–54 Read article
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Development of Anti IgG Polyclonal Antibody Against Canine IgG and Their Roles in Diagnostic Purposes
Abstract: IgG plays an important part in immunological studies and also in living bodies for providing secondary immune response which triggers as passive immunization against harmful pathogens in dogs. Purpose: The aim of this investigation is to separate, identify, and refine immunoglobulin G from canine serum. Methods: Ammonium sulphate precipitation was used to separate the dog's serum, which was then concentrated over night in a dialysis bag inside of a refrigerator. …
Published in International Journal of Vaccines · Vol. 1, Issue 2, 2024 · pp. 01–06 Read article
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Vaccination in the Era of Precision Medicine: Tailoring Immunization Strategies for Individual Risk Profiles
Abstract: The introduction of precision medicine has caused a paradigm change in the vaccine landscape. Conventionally, vaccination programmes have been homogeneous, targeting immunity at the population level without taking into consideration the individual differences in immune response and vulnerability to diseases that can be prevented by vaccination. However, a more individualised approach to immunisation has been made possible by current developments in genetics, immunology, and data analytics. Within the context of …
Published in International Journal of Vaccines · Vol. 1, Issue 2, 2024 · pp. 32–47 Read article
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Complications with Malware Identification in IoT and an Overview of Artificial Immune Approaches
Abstract: An immunity is facilitated by lymphocyte T&B-cells that possess a wide range of T&B-cell receptors, respectively. These cells can identify and react to pathogens and diseased cells by presenting peptide antigens by means of significant histocompatibility complexes (MHCs). The amount of data on the repertoire of adaptive immune receptors has increased dramatically in recent years because to advancements in deep sequencing. Furthermore, the presentation of peptides with MHC has been …
Published in Research and Reviews : A Journal of Immunology · Vol. 14, Issue 1, 2024 · pp. 54–62 Read article
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Nutritional Significance of Milk Minerals
Abstract: Mineral constituents occurs in milk and dairy products in form of organic ions and salts; however several minerals are also found associated with major milk constituents like fat, protein, carbohydrate and nucleic acid. Milk contributes significantly to the human dietary requirements of several minerals including calcium, magnesium, potassium, zinc, and phosphorus. Milk also contains some other minerals like chloride, selenium, etc in relatively less but significant amount. Numerous factors, including …
Published in Research and Reviews : Journal of Dairy Science and Technology · Vol. 13, Issue 1, 2024 · pp. 7–19 Read article
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Understanding the Impact: Adult BCG Vaccination in the Fight Against Tuberculosis
Abstract: Tuberculosis (TB) remains a big global health challenge, with significant mortality rates, especially in developing nations. India holds most TB cases throughout the globe. As HIV rates, multidrug-resistant tuberculosis (MDR-TB), and extensively drug-resistant tuberculosis (XDR-TB) continue to increase, the situation is deteriorating. These all come in the way of the End TB epidemic campaign by the World Health Organization (WHO) by 2030. Immunology and vaccinology represent critical fronts in TB …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 13, Issue 3, 2024 · pp. 1–6 Read article
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Concurrent Infection of Influenza and COVID-19: A Review
Abstract: In December 2019, a novel coronavirus that causes respiratory illnesses was identified in Wuhan, China, and swiftly spread around the world. Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is a virus that spreads via the respiratory system and can cause pneumonia. Members of the Orthomyxoviridae family include influenza viruses. Although there are four genera in this family, influenza is only caused by genera A and B, which are clinically important for …
Published in International Journal of Virus Studies · Vol. 2, Issue 1, 2025 · pp. 7–15 Read article
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Precision Medicine Approaches for Cancer Therapy Recent and Advance
Abstract: Recent advances in biotechnology have made it possible to identify intricate and distinctive biological characteristics linked to carcinogenesis. Proteomic and RNA studies, immunological markers, tumor and cell-free DNA profiling, and other methods are utilized to find these traits in order to optimize anticancer treatment for specific patients. In recent years, the focus of clinical trials has shifted considerably to enhance treatment outcomes in cancer therapy. Rather than being primarily centered …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 14, Issue 1, 2025 · pp. 1–11 Read article
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Colostrum-Driven Epigenetic Programming in Dairy Cows: A Pathway to Optimal Reproductive Health
Abstract: Colostrum is a vital nutritional source for neonatal calves, providing immune support and essential growth factors. Recent research suggests that colostrum’s impact extends beyond immediate immunological protection, influencing long-term reproductive health through epigenetic modifications. In dairy heifers, early-life exposure to high-quality colostrum may program the developing reproductive system, affecting ovarian function, uterine health, and overall fertility. The components of colostrum, including hormones, growth factors, and bioactive peptides, can induce epigenetic …
Published in Emerging Trends in Metabolites · Vol. 2, Issue 1, 2025 · pp. 35–51 Read article