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84 articles for “degenerative”
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The Effect of Vitamin C on the Reproductive Functions of Paraquat Intoxicated Male Albino Rats (Rattus norvegicus)
Abstract: Paraquat (PQ) is a bipyridylium herbicide applied around trees in Orchids and between crop rows to control broad-leaved and grassy weeds. Its oxidation results in the formation of superoxides and supernitrite species which causes damage to cellular components. Studies have implicated PQ as one of the pesticides that contributes to the reduction in male reproductive functions in humans and animals during exposure. This study, therefore, determined the antioxidant effect vitamin …
Published in Research and Reviews: A Journal of Toxicology · Vol. 4, Issue 3, 2014 · pp. 9–29 Read article
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Protective Effect of Epigallocatechin Gallate (EGCG) on Sodium Fluoride (NaF) Induced Changes in Histology of Selected Organs in Rats
Abstract: Histopathology is the microscopical examination of biological tissues to observe the appearance of diseased cells and tissues in very fine detail. The present study, has been designed to evaluate the effects of oral administration of Sodium Fluoride (NaF) 25 mg/kg/bw (orally), NaF with EGCG (40 mg/kg/bw) daily for four weeks on histological alterations, if any on heart, liver, kidney and testes of rats. Rats were weighed about 160–180 g. NaF …
Published in Research and Reviews: A Journal of Toxicology · Vol. 3, Issue 1, 2013 · pp. 20–26 Read article
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Integrated Approach of Unani Medicine in Geriatric Care
Abstract: Aging is a process of physical, psychological and social changes in multidimensional aspects. The percentage of elderly, in the world population is expected to increase rapidly from 9.5% in 1995 to 20.7% in 2050 and 30.5% in 2150. In India, the population of older people has risen from 4.9% in 1901 to 5.5% in 1951, 6.5% in 1991, 7.7% in 2001, and 8.3% in 2011 and will be 12% in …
Published in Research & Reviews : A Journal of Unani, Siddha and Homeopathy · Vol. 2, Issue 1, 2015 · pp. 4–9 Read article
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Clinical Efficacy of Laxadi Taila Janubasti in the Management of Janusandhigata Vata (Knee Osteoarthritis): A Case Report
Abstract: Background: Janusandhigata Vata, described under Sandhigata Vata in Ayurvedic classics, characterized by pain, swelling, crepitus, stiffness, and restricted movement of the knee joint. Clinically, it resembles Knee Osteoarthritis (OA), a common degenerative Musculoskeletal disorder affecting the quality of life of elderly individuals. Janubasti is a localized oleation therapy widely employed for managing degenerative knee disorders. Laxadi Taila possesses Vatahara, Balya, and Asthi-Sandhana properties that may help restore joint function and …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 15, Issue 2, 2026 · pp. 6–11 Read article
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Brief Concept of Waja ul Mafasil and its Management in Unani System of Medicine: A Review
Abstract: Waja-ul-Mafasil (Osteoarthritis) also known as degenerative arthritis is a progressive joint disease, occurring in middle and later life. Osteoarthritis is a leading cause of disability worldwide despite its development in prevention, diagnosis, and treatment. A comprehensive description of Waja-ul-Mafasil is available in classical Unani literature. While going through the literature review of various compendiums written by Unani scholars, it is clear that this system of medicine had huge knowledge about …
Published in Research & Reviews : A Journal of Unani, Siddha and Homeopathy Read article
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Image Preprocessing and Analysis on Eye Fundus Images Segmentation by Using Density Clustering Methods
Abstract: In order to do an automated evaluation of various retinal illnesses such as Diabetic retinopathy, Glaucoma, and Macular Edema, fundus images must be pre-processed first. For many reasons, it's difficult to accurately detect the optic disc. Many blood vessels cross the optic disc, making it difficult to discern the disc's boundaries in fundus images. Lesion regions in diabetic retinopathy look very much like an optic disc's colour and texture, so …
Published in Recent Trends in Sensor Research & Technology Read article
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Sugar Substitutes: Benefit or Burden
Abstract: The ubiquitous presence of sugar in our daily diet poses a considerable impact on both dental and overall health. The consensus is clear: an excess of sugar is far from ideal. Moreover, controversial conjectures have emerged, suggesting a pivotal role of excessive sugar intake in certain degenerative diseases. In response to these concerns, artificial sweeteners, also known as sugar substitutes or low-calorie sweeteners, have become increasingly appealing to consumers.Artificial sweeteners, …
Published in Research and Reviews: A Journal of Dentistry · Vol. 15, Issue 1, 2024 · pp. 7–11 Read article
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Marchiafava Bignami Syndrome: A Review
Abstract: Marchiafava-Bignami syndrome (MBS) is a rare neurological disorder characterized by demyelination and necrosis of the corpus callosum, which is the main bundle of nerve fibers connecting the two hemispheres of the brain. MBS primarily affects individuals with chronic alcoholism, although cases unrelated to alcohol consumption have also been reported. The corpus callosum is affected in almost a pathognomonic way. The clinical presentation is based on neurological impairment, motor abnormalities, seizures, …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 14, Issue 1, 2024 · pp. 21–25 Read article
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The Role of Guduchyadi Rasayana In Mental Well-Being – A Review Study
Abstract: In this era, stress is the main etiological factor behind almost every other disease. In 2020, the COVID-19 pandemic led to a notable increase in anxiety and depressive disorders worldwide. This highlighted the critical need for mental health support during such challenging times. Ageing is a biological process characterized universally by natural degeneration, standing out as a significant risk factor for morbidity and mortality. The Oxidative Stress Theory suggests that …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 13, Issue 1, 2024 · pp. 22–30 Read article
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Revolutionizing Knee Osteoarthritis Diagnosis: Unleashing the Potential of Vision Transformers
Abstract: Osteoarthritis (OA) is the most common kind of arthritis. By analysing data from both sides of the knee joints, radiologists use the Kellgren–Lawrence (KL) grading system to determine the severity of osteoarthritis (OA). The need for knee arthroplasties has increased as a result of this. Recently, there have been proposals for computer-assisted techniques to improve the precision of OA diagnosis. Choosing between conservative and surgical treatment options for knee osteoarthritis …
Published in Journal of Mechatronics and Automation · Vol. 11, Issue 1, 2024 · pp. 24–31 Read article
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X-Ray Insight: Deep Learning-Enhanced Detection and Grading of Knee Osteoarthritis
Abstract: Osteoarthritis (OA) is the most prevalent form of arthritis affecting the knee. It is a degenerative joint disease characterized by the gradual deterioration of cartilage, typically impacting individuals aged 50 and above, although it can also occur in younger people. The condition progresses slowly, with symptoms intensifying over time, leading to significant pain and discomfort. Early diagnosis and intervention can significantly alleviate pain and enhance the quality of life for …
Published in International Journal of Biomedical Innovations and Engineering · Vol. 2, Issue 2, 2024 · pp. 1–6 Read article
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Retinal Disease Detection Using Deep CNN
Abstract: Age-related macular degeneration, glaucoma, and diabetic retinopathy are the three main causes of blindness in the globe. To avoid visual loss, early identification and treatment of these disorders are essential. The goal of this research is to create an automated method for detecting retinal diseases by analyzing retinal fundus pictures with machine learning techniques. Python and the Tkinter package for the graphical user interface are used in the construction of …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 13, Issue 2, 2024 · pp. 46–50 Read article
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Refining Retinal Layer Segmentation in OCT Imaging with Advanced Techniques and Clinical Applications
Abstract: Segmenting retinal layers from Optical Coherence Tomography (OCT) pictures entails locating and separating different retinal layers to offer comprehensive anatomical and pathological information. Age-related macular degeneration, diabetic retinopathy, and glaucoma are among the retinal illnesses for which this procedure is crucial for diagnosis and follow-up. By utilizing preprocessing techniques to improve image quality and applying advanced algorithms—such as intensity-based, gradient-based, and texture-based methods—alongside deep learning approaches, clinicians can accurately measure …
Published in Trends in Opto-electro & Optical Communication · Vol. 14, Issue 2, 2024 · pp. 01–06 Read article
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Metabolic Reprogramming in Carcinogenesis: An Overview
Abstract: Metabolic reprogramming is a crucial mechanism via which cells modify their metabolic pathways to adjust to changes in the environment and maintain growth, survival, and function. This phenomenon is of utmost importance in a wide range of physiological and pathological situations, specifically in cancer, immunological responses, and stem cell biology. In cancer, metabolic reprogramming facilitates fast cell growth and survival, as demonstrated by the Warburg effect, where cancer cells prioritize …
Published in Research and Reviews: A Journal of Medicine · Vol. 14, Issue 2, 2024 · pp. 32–38 Read article
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Survey on Retinal OCT Image Preprocessing, Segmentation, and Deep Learning Based Classification
Abstract: Optical coherence tomography (OCT) is a non-invasive technique that generates high-resolution, detailed cross-sectional images of biological tissues. By utilizing low-coherence interferometry, OCT enables visualization of tissue microstructure with micron-scale resolution, making it useful in various medical fields such as ophthalmology, cardiology, and dermatology. In ophthalmology, OCT is extensively used for diagnosing and monitoring retinal diseases like macular degeneration and diabetic retinopathy, allowing doctors to assess changes in tissue morphology over …
Published in Journal of Image Processing & Pattern Recognition Progress · Vol. 11, Issue 3, 2024 · pp. 1–9 Read article
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The Analysis of Deep Learning-Based Methods for Identifying Diabetic Retinopathy
Abstract: Diabetic retinopathy (DR) is a degenerative eye condition resulting from diabetes mellitus, where high blood glucose levels lead to lesions on the retina. This condition is considered the leading cause of blindness among working-age diabetic patients, particularly in developing countries. As the disease is irreversible, the treatment aims to preserve the patient’s current vision. Early detection is crucial for effective management of DR to maintain vision. One of the main …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 13, Issue 3, 2024 · pp. 15–31 Read article
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Jabuticaba Skin Flour AsA Functional Food Ingredient: Phenolic Profile, Antioxidant Potential and Functional Technological Properties
Abstract: Brazilian-native fruit, jabuticaba, is a member of the Myrtaceae family that is typically consumed naturally. The jabuticaba skin flour (JSF) is rich in phenolic compounds, the most active antioxidants present in plants, being able to stop oxidative damage and reduce the risk of oxidative stress linked to different degenerative diseases, thus become interesting to the consumer. Despite all this antioxidant potential, little is known about their characterization and about the …
Published in Research & Reviews : Journal of Food Science & Technology · Vol. 13, Issue 3, 2024 · pp. 01–08 Read article
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Alzheimer’s Disease Detection Using ML Algorithm
Abstract: A degenerative neurological state of affairs, Alzheimer's disease (AD) gradually impairs cognitive and functional capacities, especially in people over 65. Early AD detection is crucial for efficient management and treatment prep. This study delves into novel approaches for the early detection of AD using non-invasive methods. We've implemented a blend of neuroimaging data analysis and machine learning algorithms to pinpoint markers indicative of the disease during its initial phases. Our …
Published in Journal of Experimental & Applied Mechanics · Vol. 15, Issue 3, 2024 · pp. 53–57 Read article
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An Observational Study on Prevalence and Risk Factors for OA Knee Joint Among Adult Population Attending the SCSP Camps in Chennai, Tamil Nadu, India
Abstract: Background: Osteoarthritis (OA) is a prevalent degenerative condition affecting older individuals, particularly in developing nations. It is commonly linked to aging and various intricate underlying causes. The complex causes of osteoarthritis include confounding factors that significantly increase the risk of its development, many of which can be managed or prevented. Among all joints, knee osteoarthritis is particularly prevalent, especially in women. In rural India, the SC/ST population faces significant health …
Published in Research & Reviews : A Journal of Unani, Siddha and Homeopathy · Vol. 12, Issue 1, 2025 · pp. 9–17 Read article
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Advances in Total Knee Replacement: A Systematic Review of Clinical Outcomes and Complications
Abstract: Total Knee Replacement (TKR) is a widely used surgical intervention for patients with knee osteoarthritis and other degenerative knee disorders, offering significant improvements in pain relief, functional restoration, and quality of life. This systematic review synthesizes data from multiple clinical studies to evaluate the outcomes and complications associated with TKR. To find applicable research published in the last ten years, a thorough search of electronic databases was performed. Randomised controlled …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 14, Issue 1, 2024 · pp. 41–56 Read article