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30 articles for “T2D”
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Exploring Type-II Diabetes Potential of Phyto-Derived Carbon Dots
Abstract: The integration of phytoconstituents with carbon dots (C-dots) presents a novel and sustainable approach to the development of nanotherapeutics for type 2 diabetes mellitus (T2DM). C-dots, zero-dimensional carbon-based nanomaterials, exhibit unique physicochemical properties including high fluorescence, tunable surface chemistry, biocompatibility, and low toxicity. Their ability to enhance the solubility, bioavailability, and targeted delivery of poorly soluble phytochemicals renders them highly suitable for biomedical applications. This study explores the synthesis of …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 16, Issue 3, 2025 · pp. 08–25 Read article
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Association between Diabetes Type and Family History of Diabetes: A Cross-Sectional Analysis of Gender Differences and Genetic Influences
Abstract: Introduction: Diabetes mellitus DM is one of the fast-growing chronic metabolic disorder in the world, with high impact and burden in low- and middle-income country. Although genetic predisposition is a central determinant of diabetes risk, particularly for Type 2 diabetes (T2D), the contribution of familial aggregation varies across populations. In many parts of the world where diabetes is rising very fast understanding the relationship between diabetes type and family history …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 15, Issue 3, 2025 · pp. 43–50 Read article
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GLP-1 Receptor Agonists: A Dual Therapeutic Strategy for the Management of Type 2 Diabetes Mellitus and Obesity
Abstract: For the treatment of obesity and type 2 diabetes mellitus (T2DM), glucagon-like peptide-1 receptor agonists (GLP-1 RAs) have become a revolutionary class of pharmaceutical drugs. These drugs were first created as glucose-lowering treatments, but they have now shown other advantages, such as notable weight loss, better cardiovascular results, and general metabolic control. The objective of this narrative review is to assess the pharmacological mechanisms, clinical efficacy, safety profile, and therapeutic …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 16, Issue 1, 2026 · pp. 69–75 Read article
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SGLT2 Inhibitors in Heart Failure and Chronic Kidney Disease: Expanding Therapeutic Horizons beyond Glycemic Control
Abstract: Heart failure (HF) and chronic kidney disease (CKD) are closely related clinical diseases that significantly increase morbidity and death worldwide. The co-occurrence of both conditions is frequently referred to as the "cardio-renal syndrome," in which the failure of one organ hastens the decline of the other. The original purpose of sodium–glucose cotransporter-2 (SGLT2) inhibitors was to treat type 2 diabetic mellitus (T2DM) by reducing blood sugar levels. Nevertheless, new data …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 16, Issue 2, 2026 Read article
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Correlation of Serum Vitamin D Levels with Insulin Resistance in Young Adults
Abstract: Among young adults, both insulin resistance (IR)and vitamin D deficiency are common and pose the risk of complications, such as type 2 diabetes mellitus (T2DM). A few studies demonstrated that vitamin D deficiency might negatively influence insulin sensitivity, but the results of these studies have been inconsistent and/or inconclusive. This review focuses on young adults and aims to summarize and critique studies that assess the relationship between IR and serum …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 15, Issue 1, 2026 · pp. 69–74 Read article
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Lipid Profile Analysis in Type 2 Diabetes Mellitus Patients Belonging to Kota South
Abstract: Background: Diabetes mellitus is a category of metabolic disorders marked by persistently high blood sugar levels and abnormalities in the metabolism of fats, proteins, and carbohydrates as a result of deficiencies in the secretion or action of insulin, or both. Diabetic dyslipidemia is characterized by elevated low-density lipoprotein cholesterol (LDL-C), reduced high-density lipoprotein cholesterol (HDL-C), and increased triglyceride (TG) levels. The objective of this study is to assess the lipid …
Published in Research and Reviews : A Journal of Immunology · Vol. 13, Issue 2, 2023 · pp. 38–41 Read article
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PREVENTION AND CONTROL OF DIABETES MELLITUS (DM) WITH DIETOTHERAPY: A REVIEW
Abstract: Prevalence of type II diabetes mellitus (T2DM) have been increasing throughout the world day by day, to an extent that the condition has reached the epidemic proportions in many countries. One of the main reasons for increasing diabetic cases is the sedentary lifestyle, intake of junk food and obesity. Unhealthy eating with profound dependence on junk food, is the major reason for increasing lifestyle diseases like Diabetes Mellitus. Greco-Arab and …
Published in Research & Reviews : A Journal of Unani, Siddha and Homeopathy · Vol. 7, Issue 2, 2020 · pp. 10–19 Read article
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Diabetic Level Prediction in Humans: Using Supervised Machine Learning Methods
Abstract: Diabetes could be an unremitting malady or a metabolic sick wellbeing cluster where an individual endures from a pervasive sum of insulin-producing blood glucose within the body or since the cells of the body do not react to affront. Steady diabetes hyperglycemia is the damage to long term organs, particularly lungs, kidneys, nerves, the heart and the veins are connected to weakness and misfortune. The objective of this investigation is …
Published in Recent Trends in Parallel Computing · Vol. 7, Issue 1, 2020 · pp. 1–6 Read article
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Efficient Identification of Complex Diseases Through Epistasis Computational Models: A Review
Abstract: AbstractGenome-Wide Association Studies (GWAS) identify and characterize the genes that are associated with human diseases. One of the significant ongoing researches in GWAS is to identify the disease susceptible genes through Epistasis. The gene that masks the effects of other genes is called Epistasis. The gene interacts with another gene is known as epistatic or genetic interactions (GGIs). GWAS identifies the genetic variants of Single Nucleotide Polymorphism and also the …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 7, Issue 2, 2020 · pp. 21–32 Read article
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Study the Effect of Antioxidant and Antidiabetic Property of the Selective Indian Herbal Plant Extract (A. indicum) on Type II Diabetes Mellitus
Abstract: Abutilon indicum (A. indicum) is a traditional Indian phytomedicine plant used for the treatment of several diseases such as diabetes mellitus, cardiac diseases and anti-inflammatory diseases. The aim of the study was to evaluate whether A. indicum improves insulin sensitivity and determine its active role in bioactive secondary metabolites. Aldose reductase is an enzyme which contains lower affinity towards glucose and helps in converting glucose to sorbitol and slightly catalyzed. …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 9, Issue 1, 2019 · pp. 53–63 Read article