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216 articles for “Insulin/IGF1-AKT-mTOR”
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Nutrient Composition and Quality Evaluation of Composite Bread with Jackfruit (Artocarpus heterophyllus) Seed Flour
Abstract: Jackfruit (Artocarpus heterophyllus) seeds were used to develop composite bread; and nutritional quality and sensory properties of the resulting breads were evaluated. The percentage of jackfruit seed flour (JSF) used in preparing the bread was 5%, 10%, 15% and 20%. From the proximate analysis it was found that the whole wheat flour and JSF contained 12.56% and 13.14% of protein, 0.85% and 0.80% of fat, 0.62% and 1.82% of ash, …
Published in Research & Reviews : Journal of Food Science & Technology · Vol. 6, Issue 2, 2017 · pp. 40–48 Read article
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Effect of Polyherbal Compound (Low Cost) in Management of Insulin Dependent Diabetes Mellitus
Abstract: Diabetes mellitus is chronic ailment associated with life threating target organ damage. The present approach of treatment is to maintain glycaemic level within physiological normal level with different means, which may favour angiopathic changes even with normal blood sugar. Ayurveda believes that Medas i.e. lipid metabolism is important pathological change observed in DM that ends up presentation of elevated level of peripheral blood sugar. The quest is to come with …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 3, Issue 2, 2016 · pp. 31–34 Read article
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Revolutionizing Diabetes Management: Nanostructured Biosensors for Real-time Monitoring
Abstract: Chronic metabolic disease known as diabetes mellitus, which is characterized by dysregulated blood glucose levels, is becoming a major global health concern. The implementation of automated insulin administration systems and continuous glucose monitoring (CGM) has shown promise in the management of diabetes. Nanostructured biosensors, leveraging the unique properties of nanomaterials, offer enhanced sensitivity, selectivity, and biocompatibility, making them ideal candidates for real-time monitoring and personalized treatment. This article delves into …
Published in Journal of Nanoscience, NanoEngineering & Applications · Vol. 14, Issue 1, 2024 · pp. 49–70 Read article
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Diabetes Prediction Using ML Techniques
Abstract: Diabetes mellitus, commonly referred to as diabetes, denotes a cluster of prevalent endocrine disorders characterized by persistent elevated levels of blood sugar. Diabetes is classified into two main types: type 1 and type 2. Type 1 diabetes arises when the body is unable to produce insulin, while type 2 diabetes involves either insulin resistance or insufficient insulin production. Early detection and intervention are essential to reduce its harmful impacts. The …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 11, Issue 3, 2024 · pp. 1–9 Read article
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Nano-Therapeutics in Diabetes Mellitus: Revolutionizing Diagnosis, Treatment, and Drug Delivery
Abstract: Diabetes mellitus is a chronic metabolic disorder in which blood glucose concentration remains high over an extended duration, resulting in significant lethal complications, including neuropathy, nephropathy and cardiovascular diseases. However, conventional diabetes management strategies, including insulin therapy and oral hypoglycemic agents, rarely exhibit poor bioavailability, high doses, off target delivery, etc. Nanotechnology has brought the rise of diabetes treatment revolution, by overcoming the challenges present in standard treatment, owing to …
Published in Trends in Drug Delivery · Vol. 12, Issue 2, 2025 · pp. 08–19 Read article
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Modeling of Patient of Type 1 Diabetes for Blood Glucose Control
Abstract: The recent development in the insulin delivery system is the automatic one. The blood glucose levels are controlled by the feedback loop. The initial success with the simple models in normalizing blood glucose level led to the improvement of the devices including variety of control system. The insulin delivery system to diabetic is a tedious job and doesn’t ensure proper performance and leads to various complications if the delivery of …
Published in Journal of Microelectronics and Solid State Devices · Vol. 3, Issue 1, 2016 · pp. 30–35 Read article
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Type 2 Diabetic Dyslipidemia: A Review
Abstract: Diabetic dyslipidemia is a pathological condition where persistent rise in blood glucose level gives rise to derangement of lipids vis-a vis lipoproteins; which in turn increases the risk of cardiovascular diseases. Although both forms of diabetes mellitus that is, Diabetes mellitus Type-1 (insulin-dependent diabetes mellitus or IDDM) and Diabetes mellitus Type-2 (non-insulin-dependent diabetes mellitus or NIDDM) can alter lipid arrangement but Type-2 is more common (80–90%) form of diabetes mellitus, …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 10, Issue 2, 2021 · pp. 58–63 Read article
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Flaxseed and Diabetes Management: A Comprehensive Review of Recent Studies and Potential Mechanisms
Abstract: Diabetes mellitus, a condition characterized by chronic hyperglycemia, has become a significant global health challenge, leading to substantial morbidity and mortality rates. Dietary techniques are crucial for the effective control of diabetes, including both pharmaceutical and non-pharmacological therapies. Flaxseed (Linum usitatissimum) is one of the functional foods that has attracted a lot of interest because of its abundance of bioactive components, including lignans, dietary fiber, and alpha-linolenic acid (ALA). The …
Published in International Journal of Nutritions · Vol. 2, Issue 1, 2025 · pp. 24–32 Read article
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Review on the Efficacy of Ayurvedic Formulations in Diabetes Management
Abstract: Diabetes mellitus is one of the most prevalent metabolic disorders globally, characterized by persistent hyperglycemia resulting from defects in insulin secretion, insulin action, or both. It leads to serious complications affecting the cardiovascular, renal, and nervous systems, imposing a significant health and economic burden. In Ayurveda, diabetes is described as Madhumeha, a subtype of Prameha, primarily caused by the vitiation of Kapha dosha, Meda dhatu (fat metabolism), and Agnimandya (impaired …
Published in Research and Reviews : A Journal of Ayurvedic Science, Yoga and Naturopathy · Vol. 13, Issue 1, 2026 · pp. 16–22 Read article
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Novel Nanotherapeutics for the Management of Diabetes
Abstract: Diabetes is a severe chronic disorder with hyperglycemia, either due to dysfunctional pancreas(Type I) or due to malfunctioned glucose utilizing entities like: liver, straight muscle or adipocytes (Type II). Type 1 or Insulin-dependent/Juvenile diabetes and Type 2 Diabetes Mellitus or Non-Insulin dependent/Adult-onset diabetes are the two broad classifications of diabetes. In case of type 1 diabetes injectable insulin is the major form of medication given and in case of Type …
Published in Nano Trends – A Journal of Nano Technology & Its Applications · Vol. 26, Issue 1, 2024 · pp. 46–67 Read article
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The Interplay Between Hyperglycemia, Endothelial Dysfunction, and Cardiovascular Risk in the Context of COVID-19: Implications for Long-term Health
Abstract: The COVID-19 pandemic has highlighted the potential impact of hyperglycemia, especially its link to cardiovascular disease (CVD) and endothelial dysfunction. COVID-19 can cause systemic inflammation and endothelial damage, worsening complications related to hyperglycemia. Persistent inflammation and endothelial dysfunction are crucial elements in the progression of atherosclerosis and other cardiovascular diseases. The long-term health effects of COVID-19, known as “Long COVID” or post-acute sequelae of SARS-CoV-2 infection (PASC), have raised concerns …
Published in Research and Reviews: A Journal of Medicine · Vol. 14, Issue 2, 2024 · pp. 27–31 Read article
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Rethinking Type-1 Diabetes Treatment: Emerging Medicines Based on AAT Therapy and C-peptide Preservation Therapy
Abstract: The increasing number of cases, especially in the younger age group, along with the lack of accessible clinical solutions, make Type-1 Diabetes (T1D) a growing global health concern. While gene therapy and transplantation approaches are promising avenues, their excessively high costs and logistical difficulties make them inaccessible to the majority and can impose a financial burden on those suffering from it, adding to the challenges already faced by these advanced …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 14, Issue 3, 2024 · pp. 19–29 Read article
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Role of Genetics in Improving Fitness and Sports Performance
Abstract: Research indicates that variations in specific genes affects sports performance, comparing athletes with nonathletes. The genes that have been examined the most in relation to athletic performance are ACE and ACTN3. Strength and endurance have been associated with these genes, which also affect the type of fiber that makes up muscles. Sports performance factors primarily affected by genes are intrinsic motivation to exercise, power and endurance potential, training response to …
Published in Recent Trends in Sports · Vol. 1, Issue 2, 2024 · pp. 28–34 Read article
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The Therapeutic Potential of Nutraceutical in Diabetes Management: A Comprehensive Review
Abstract: Diabetes is a long-term and complex condition characterized by high blood sugar levels resulting from inadequate insulin production, ineffective insulin function, or a combination of both. Various nutraceuticals used in clinical settings have shown beneficial impacts on a range of biochemical and clinical markers related to diabetes. In many traditional medical systems, hypoglycemic agents derived from plants are used to treat, manage, and prevent diabetes mellitus. These plant extracts have …
Published in Emerging Trends in Metabolites · Vol. 2, Issue 1, 2025 · pp. 20–27 Read article
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Understanding Metabolic Syndrome and its Nutritional Management
Abstract: Metabolic syndrome (MetS) is a collection of risk factors, especially when at least three occur together, including abdominal obesity, dyslipidemia, low high-density lipoprotein cholesterol (HDL-c) levels, hypertension, and insulin resistance. MetS is linked to an increased risk of diabetes and cardiovascular diseases (CVDs) if treatment is not received.The causes of MetS include both genetic and acquired factors that contribute to issues such as insulin resistance, chronic low-grade inflammation, and obesity. …
Published in International Journal of Sustainability · Vol. 2, Issue 1, 2025 · pp. 26–37 Read article
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Postbiotics Unveiled: Mechanistic Insights and Therapeutic Implications in Obesity.
Abstract: The burgeoning global obesity epidemic necessitates innovative therapeutic approaches, and postbiotics, bioactive compounds arising from microbial fermentation, have emerged as promising contenders in reshaping obesity management. This comprehensive review explores the multifaceted mechanisms by which postbiotics impact obesity, from modulating gut microbiota composition to influencing metabolic pathways and enhancing energy expenditure. The exploration of postbiotics is rooted in a deeper understanding of the gut–brain axis and bidirectional communication between gut …
Published in Emerging Trends in Metabolites · Vol. 3, Issue 1, 2026 · pp. 11–28 Read article
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Increase of Glucose in Fasting condition –A review
Abstract: Estimation of blood glucose is very important for normal and diabetic cases. Fasting blood sugar is measurement after overnight fasting, values above 125 mg/dl indicates diabetes while post prandial sugar is sugar after meal, which is done after four hours meals. It has been seen that post prandial sugar levels are always higher compared to fasting but in few cases fasting levels were found elevated when compared to post prandial …
Published in Research and Reviews : A Journal of Immunology · Vol. 12, Issue 3, 2022 · pp. 23–26 Read article
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Anti-Diarrhoeal Effects of Probiotics on Children
Abstract: Diarrhoeal disease is one of the major problems among under-five year children in Bangladesh. Probiotics have been suggested to be used in acute diarrhoea. Several different probiotics are commercially available in our country. The objective of this experimental study was to assess the effects of probiotics among under-five year children suffering from diarrhoea. This study was conducted using probiotics with oral rehydration solution (ORS) and ORS only which were given …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 8, Issue 1, 2018 · pp. 15–21 Read article
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Productivity of Phytoplankton by Using Different Organic Fertilizers in the Glass Aquarium
Abstract: The experiment intended to estimate the productivity using different organic fertilizer and to identify the species of phytoplankton in the aquarium tanks. The study was conducted in the laboratory of Department of Fisheries and Marine Bioscience (FMB), Jashore University of Science and Technology, Jashore, Bangladesh during November to December, 2013. Phytoplankton samples for culture were collected from fisheries experimental pond by using conical-shaped monofilament nylon net (phytoplankton net). Three treatment …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 6, Issue 1, 2019 · pp. 25–37 Read article
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Collection and Evaluation of Ber Germplasm
Abstract: An experiment to identify suitable ber germplasm was conducted at Horticulture Research Centre (HRC) fruit orchard, Regional Agricultural Research Station (RARS), Bangladesh Agricultural Research Institute (BARI), Jamalpur, Bangladesh during the fruiting season of 2016-2017. Fifty-eight accessions collected from different parts of Bangladesh were included in the study. The scion of the collected germplasm was grafted on 10 years old ber plant and the age of grafted branches was 3 years …
Published in Research & Reviews : Journal of Agricultural Science and Technology · Vol. 6, Issue 3, 2017 · pp. 24–39 Read article