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485 articles for “Mechanism” (ranking capped at the first 2,000 matches — narrow the search to see the rest)
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Understanding Leukemogenesis: Challenges and Advancements in Diagnostic Approaches
Abstract: Leukaemia development, or leukemogenesis, is a multifactorial process driven by a complex interplay of environmental, genetic, and epigenetic factors. Despite substantial advancements in technology and medicine, which have enhanced our understanding of the contributing factors, early and accurate diagnosis remains a major challenge due to the overlapping clinical features shared by the various leukaemia subtypes. This study explores the molecular and cellular mechanisms underlying leukemogenesis, while also addressing the difficulties …
Published in International Journal of Biomedical Innovations and Engineering · Vol. 3, Issue 1, 2025 · pp. 11–22 Read article
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Smart Street Lighting Enabled by Wireless Sensor Networks: A Path to Energy Efficiency and Fault Monitoring
Abstract: The increasing demand for energy efficiency and smart city infrastructure has led to the adoption of innovative technologies such as wireless sensor networks (WSNs) in street lighting systems. This research explores the design and implementation of a smart street lighting system (SSLS) integrated with WSNs to enhance energy efficiency and enable real-time fault detection. The proposed system utilizes a network of wireless sensors to monitor ambient light levels, vehicular movement, …
Published in International Journal of Wireless Security and Networks · Vol. 3, Issue 1, 2025 · pp. 24–38 Read article
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Integrating Atmospheric Science: Understanding Greenhouse Gases, Aerosols, and Air Quality Dynamics
Abstract: Atmospheric science investigates the Earth’s atmospheric systems to understand their composition, dynamics, and the implications for climate, weather, and air quality. This review explores five primary areas within the field: atmospheric composition, atmospheric modeling, remote sensing, air pollution, and boundary layer dynamics, highlighting critical challenges and advancements. Rising levels of greenhouse gases (GHGs), including carbon dioxide and methane, continue to drive global warming, while feedback mechanisms—like cloud interactions and surface …
Published in International Journal of Atmosphere · Vol. 1, Issue 1, 2024 · pp. 32–35 Read article
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An Efficient Synthesis of Some Novel Benzo Coumarin Derivatives Under Solvent Conditions from 2-acetyl-benzo[f]chromen-3-one
Abstract: The synthesis of the target compounds began with the preparation of 2-[3-dimethylamino[acryloyl-3H-benzo[f]chromen-3-one. This intermediate was obtained through the reaction of 2-acetylbenzo[f]coumarin-3-one with N,N-dimethylformamide dimethyl acetal [DMFDMA[ under reflux conditions in xylene. The enaminone thus formed was subsequently reacted with 6-aminothiouracil in acetic acid, leading to the formation of 2-thioxo-2,3-dihydro-1H-pyrido[2,3-d]pyrimidin-4-one. This compound served as a pivotal intermediate for the synthesis of a series of pyridotriazolopyrimidinones. These derivatives were synthesized by reacting …
Published in International Journal of Cheminformatics · Vol. 2, Issue 2, 2024 · pp. 33–46 Read article
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The Effectiveness of Personal Carbon Trading for Sustainable Urban Development in Developing Nations: An Overview
Abstract: In recent decades, humankind has evolved much more rapidly than the ages. This evolution resulted in tremendous technological advancement and massive planetary degeneration. Enormous greenhouse gas emissions have resulted from the quick increase in energy and fossil fuel consumption patterns brought on by technological breakthroughs. Eventually, the scenario contributed to rising per capita carbon emissions manifolds, especially in highly populated cities. Reduced per capita carbon footprints are the goal of …
Published in International Journal of Environmental Planning and Development Architecture · Vol. 3, Issue 1, 2025 · pp. 33–46 Read article
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Computational Identification of Antigenic Proteins and Epitopes in Hantavirus sp. for Drug Repurposing
Abstract: Hantavirus is an emerging virus that spreads from animals to humans and can cause serious illnesses like hantavirus pulmonary syndrome (HPS) and hemorrhagic fever with renal syndrome (HFRS). there are no FDA-approved treatments available for these diseases. This study explores in-silico drug repurposing as a strategy to identify potential therapeutic candidates. The physicochemical, secondary structure, antigenicity, and post-translational modification analysis of hantavirus proteins – specifically the glycoprotein precursor, N protein, …
Published in International Journal of Molecular Biotechnological Research · Vol. 3, Issue 1, 2025 · pp. 20–26 Read article
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Toxic Trails: Land Degradation Induced By Pollutants
Abstract: Land degradation, driven by various pollutants, poses a significant threat to global ecosystems, agriculture, and human well-being. This review article explores the mechanisms through which pollutants, including heavy metals, pesticides, industrial chemicals, and urban waste, contribute to soil erosion, salinization, acidification, and loss of soil biodiversity. The article presents detailed case studies from regions such as China, India, Nigeria, the United States, Europe, Sub-Saharan Africa, and Australia, highlighting the diverse …
Published in International Journal of Land · Vol. 1, Issue 1, 2024 · pp. 37–45 Read article
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Tobacco and COVID-19: Molecular Interactions and Public Health Challenges – A Review
Abstract: Tobacco use exacerbates health risks, making it a significant concern during the COVID-19 pandemic. Smoking has been implicated in the upregulation of ACE2 receptors, critical for SARS- CoV-2 entry, and contributes to immune dysregulation and oxidative stress, worsening clinical outcomes. Methods: This review synthesizes evidence on the molecular mechanisms linking tobacco and COVID-19, assesses risk factors, such as smoking status and comorbidities, and explores public health challenges in managing the …
Published in International Journal of Virus Studies · Vol. 2, Issue 1, 2025 · pp. 1–6 Read article
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Optimizing Data Processing Efficiency in Big Data: Advanced MapReduce Algorithm Innovations
Abstract: The exponential growth of big data in recent years has created an urgent need for innovative and efficient processing frameworks capable of managing and analyzing massive and complex datasets. Among these, MapReduce has gained prominence as a powerful tool for distributed data processing due to its simplicity and scalability. However, traditional MapReduce frameworks often encounter significant limitations in terms of efficiency, scalability, and resource optimization, particularly when handling large-scale and …
Published in International Journal of Data Structure Studies · Vol. 3, Issue 1, 2025 · pp. 1–7 Read article
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Accelerating Innovation: Design, Development, and Manufacturing of Artificial Intelligence- Enhanced Smart Electric Vehicles
Abstract: This research paper delves into the dynamic landscape of automotive engineering, focusing on the accelerated innovation facilitated by the integration of artificial intelligence (AI) in the design, development, and manufacturing processes of smart electric vehicles (SEVs). With sustainability and efficiency at the forefront of contemporary transportation initiatives, SEVs stand as a beacon of technological advancement, offering a paradigm shift towards eco-friendly mobility solutions. By harnessing the power of AI algorithms, …
Published in International Journal of Manufacturing and Production Engineering · Vol. 3, Issue 1, 2025 · pp. 9–25 Read article
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Monkeypox Virus (MPXV): Epidemiology, Pathogenesis, and Control Strategies: Exploring the Recent Resurgence of Monkeypox, Its Transmission Dynamics, Clinical Manifestations, and Public Health Responses
Abstract: Monkeypox virus (MPXV) has re-emerged as a significant public health concern, with increasing cases reported worldwide. This zoonotic virus, primarily endemic to Central and West Africa, has demonstrated the potential for human-to-human transmission, leading to outbreaks in non-endemic regions. Unlike smallpox, which was eradicated through mass vaccination, monkeypox continues to persist due to the lack of widespread immunity and effective antiviral treatments. The resurgence of MPXV in recent years, particularly …
Published in International Journal of Virus Studies · Vol. 2, Issue 1, 2025 · pp. 29–34 Read article
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Climate Change and the Spread of Pathogens: Implications for Public Health
Abstract: Climate change plays a significant role in the spread of infectious diseases by shifting how pathogens behave, affecting how vulnerable hosts are, and changing the way diseases are transmitted.Rising global temperatures, changing precipitation levels, and extreme weather events are accelerating the spread of bacteria, viruses, fungi, and parasites, increasing the risk of outbreaks worldwide. Warmer conditions favor the survival and expansion of vector-borne diseases such as malaria, dengue, and Zika …
Published in International Journal of Pathogens · Vol. 2, Issue 1, 2025 · pp. 1–5 Read article
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Pathogens in Nosocomial Infections: Epidemiology, Resistance, and Control Measures
Abstract: Nosocomial infections, also known as healthcare-associated infections (HAIs), are a serious global health issue, leading to higher patient morbidity, prolonged hospital stays, and increased medical costs. Various pathogens—such as bacteria, viruses, fungi, and parasites—are responsible for these infections, especially in healthcare environments where they easily spread. They can be transmitted through direct contact with infected patients, contaminated medical equipment, or even airborne particles.Patients with weakened immune systems, those requiring prolonged …
Published in International Journal of Pathogens · Vol. 2, Issue 1, 2025 · pp. 12–16 Read article
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Emerging Trends in Membrane-Based Gas Separation Technologies
Abstract: Membrane technology has emerged as a groundbreaking solution in various fields, revolutionizing industries such as water treatment, energy production, biomedicine, and environmental protection. Over the past few decades, significant advancements have been made in membrane materials, fabrication techniques, and performance optimization. With the growing global demand for efficient and sustainable separation processes, research has increasingly focused on enhancing membrane permeability, selectivity, and durability to improve performance across various industries, including …
Published in International Journal of Membranes · Vol. 2, Issue 1, 2025 · pp. 16–22 Read article
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Rosemary: A Natural Way to Improve Brain Health and Cognitive Function
Abstract: Cognitive decline is a common consequence of aging, often leading to diminished quality of life. Although conventional drug treatments, such as anticholinesterase inhibitors, are available for managing cognitive decline, they are not always effective in older adults and may even induce adverse effects. As a result, there has been growing interest in natural alternatives, particularly traditional herbal medicines, for their potential cognitive-enhancing properties. Among these, Rosmarinus officinalis (Rosemary) has gained …
Published in International Journal of Brain Sciences · Vol. 2, Issue 1, 2025 · pp. 30–36 Read article
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A Comprehensive Review on Neturaceuticals in Alzheimer's and Neurodegenerative Disease an Cognitive Enhancement
Abstract: Neurodegenerative diseases, including Alzheimers disease (AD), Parkinsons disease (PD), and related cognitive disorders, represent a significant and growing public health challenge, particularly in aging populations. Despite advances in pharmacological treatments, therapeutic options for cognitive decline and neurodegeneration remain limited. Recent interest has shifted towards nutraceuticals— bioactive compounds derived from food or natural sources—as promising adjuncts or alternatives in the management of these conditions. This review examines how nutraceuticals can help …
Published in International Journal of Brain Sciences · Vol. 2, Issue 1, 2025 · pp. 1–9 Read article
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Assessment of Differential Global Positioning System (DGPS Technology for Generating Accurate Topographic Maps and Controls: A Case Study of Farin-Lamba to Kwali College Area
Abstract: This study investigates the application of Differential Global Positioning System (DGPS) for topographic mapping and control point establishment in Farin-Lamba to Kwali College Area. The second order Survey controls extension are critical indices for ensuring structural and border control mechanisms in environmental development projects. However, creating these controls using traditional ways presents major obstacles. Most modern techniques are improvements on ancient approaches, which raises the possibility of environmental dangers and …
Published in International Journal of Land · Vol. 2, Issue 1, 2025 · pp. 11–23 Read article
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Hormonal Shifts and Vision Changes: Addressing the Needs of Women During and After Pregnancy
Abstract: Pregnancy and the postpartum period are marked by significant hormonal fluctuations that can profoundly affect a woman’s vision health. This review explores the relationship between hormonal shifts during pregnancy and the onset of common vision changes, including but not limited to dry eyes, blurred vision, and retinal changes. These changes are often temporary but can indicate underlying complications such as gestational diabetes, preeclampsia, and other pregnancy-related conditions that may threaten …
Published in International Journal of Women's Health Nursing And Practices · Vol. 3, Issue 1, 2025 · pp. 19–24 Read article
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Colostrum-Driven Epigenetic Programming in Dairy Cows: A Pathway to Optimal Reproductive Health
Abstract: Colostrum is a vital nutritional source for neonatal calves, providing immune support and essential growth factors. Recent research suggests that colostrum’s impact extends beyond immediate immunological protection, influencing long-term reproductive health through epigenetic modifications. In dairy heifers, early-life exposure to high-quality colostrum may program the developing reproductive system, affecting ovarian function, uterine health, and overall fertility. The components of colostrum, including hormones, growth factors, and bioactive peptides, can induce epigenetic …
Published in Emerging Trends in Metabolites · Vol. 2, Issue 1, 2025 · pp. 35–51 Read article
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Advancements in Plant Molecular Biology and Genetics: Insights into Genetic Engineering, Genomics, and Crop Improvement
Abstract: This comprehensive review explores the rapidly advancing fields of plant molecular biology and genetics, offering a thorough examination of contemporary research and innovative methodologies that contribute to a deeper understanding of plant development, improved crop productivity, and the mitigation of environmental challenges. Recent breakthroughs in genetic engineering, genomics, and transcriptomics are thoroughly analyzed to provide valuable insights into their practical applications for sustainable agriculture. The integration of cutting-edge tools and …
Published in International Journal of Trends in Horticulture · Vol. 2, Issue 1, 2025 · pp. 25–27 Read article