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404 articles for “anal disease”
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Exploring Azadirachta indica’s Potential to Combat Visceral Leishmaniasis Through GP63 Inhibition
Abstract: Objectives: Millions of people worldwide suffer from the parasite disease visceral leishmaniasis. Determine the naturally occurring active ingredients in Azadirachta indica, which are employed as a disease-prevention agent and have several uses in medicine. To choose the best ligand to use as a medication, absorption, distribution, metabolism, and excretion (ADME) studies and molecular docking are employed. Methods: To obtain the GP63 protein, the Protein Data Bank (PDB) database was accessed. …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 2, Issue 2, 2024 · pp. 1–12 Read article
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Advancements in Plant Molecular Biology and Genetics: Insights into Genetic Engineering, Genomics, and Crop Improvement
Abstract: This comprehensive review explores the rapidly advancing fields of plant molecular biology and genetics, offering a thorough examination of contemporary research and innovative methodologies that contribute to a deeper understanding of plant development, improved crop productivity, and the mitigation of environmental challenges. Recent breakthroughs in genetic engineering, genomics, and transcriptomics are thoroughly analyzed to provide valuable insights into their practical applications for sustainable agriculture. The integration of cutting-edge tools and …
Published in International Journal of Trends in Horticulture · Vol. 2, Issue 1, 2025 · pp. 25–27 Read article
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Phytoremediation for Remediating Waste Water in Nandanpura Area, Jhansi (U. P.)
Abstract: Water is the most essential commodity in our day to day life. It is unimaginable to survive without water. Access to clean water has emerged as a major issue globally. The Nandanpura area in Jhansi faces significant challenges with wastewater management, impacting both the environment and public health. Contamination of heavy metals such as Zinc, Copper, Cadmium etc have caused a lot of harmful diseases in human beings. In order …
Published in International Journal of Pollution: Prevention & Control · Vol. 3, Issue 1, 2025 · pp. 36–46 Read article
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Jabuticaba Skin Flour AsA Functional Food Ingredient: Phenolic Profile, Antioxidant Potential and Functional Technological Properties
Abstract: Brazilian-native fruit, jabuticaba, is a member of the Myrtaceae family that is typically consumed naturally. The jabuticaba skin flour (JSF) is rich in phenolic compounds, the most active antioxidants present in plants, being able to stop oxidative damage and reduce the risk of oxidative stress linked to different degenerative diseases, thus become interesting to the consumer. Despite all this antioxidant potential, little is known about their characterization and about the …
Published in Research & Reviews : Journal of Food Science & Technology · Vol. 13, Issue 3, 2024 · pp. 01–08 Read article
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Utilizing circulation-derived cancer cells to evaluate patients with surgically treated stages I–IIIA NSCLC throughout the preoperative phase
Abstract: Context: When a tumor is considered resectable, surgery is viewed as the primary treatment approach for both early-stage and locally advanced non-small cell lung cancer (NSCLC). One of the most exciting areas of cancer research in the past ten years is liquid biopsy, which offers a practical non-invasive method for cancer detection and tracking. Circulating tumor cells (CTCs) have been linked to a worse prognosis and increased chance of relapse …
Published in Research and Reviews : Journal of Surgery · Vol. 13, Issue 3, 2024 · pp. 17–28 Read article
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Adoption of Artificial Intelligence in Periodontal Diagnostics: Awareness, Confidence, and Barriers Among Dental Practitioners in India
Abstract: AI has emerged as a transformative tool in healthcare, including periodontics, where it aids in diagnosing periodontal diseases, assessing bone loss, and predicting disease progression. Despite its potential, the adoption of AI in dentistry, particularly in India, remains limited. This study aimed to evaluate the awareness, confidence, and willingness of dental practitioners to adopt AI-based tools in periodontal diagnostics. A cross-sectional survey was conducted among 106 dental practitioners, including general …
Published in Research and Reviews: A Journal of Dentistry · Vol. 16, Issue 3, 2025 · pp. 27–38 Read article
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A Knowledge Graph Approach for Breast Cancer Diagnosis and Data Sharing Platform Implementation in the Context of Human Papillomavirus Infection
Abstract: Background: Breast cancer remains among the most prevalent malignancies in women worldwide, and effective diagnosis and data integration continue to challenge clinical practice. Diagnostic reports from mammography and ultrasound contain rich clinical information that is often under-utilised due to heterogeneous formats and limited data-sharing infrastructure. In the context of human papillomavirus (HPV) infection, which may influence oncogenic pathways and data complexity, advanced computational methods offer new solutions to this problem. …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 15, Issue 1, 2026 Read article
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Lung Function Decline Among Brick Kiln Workers in Haryana Due to Chronic Particulate Matter Exposure
Abstract: In Haryana, India, brick kiln workers are subjected to high levels of Particulate Matter (PM) which has been shown to deteriorate respiratory health. This study looks into the effect sustained exposure to particulate pollution has on lung function among workers in the brick kilns. The objective of the study was to assess the impact of chronic exposure to particulate matter on lung function among brick kiln workers in Haryana. A …
Published in Journal of Industrial Safety Engineering · Vol. 12, Issue 2, 2025 · pp. 11–16 Read article
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Metabolic Syndrome in Psoriatic Patients: A Cross-Sectional Study
Abstract: Background: Psoriasis is a chronic immuno-inflammatory disease affecting the skin and joints. Studies have demonstrated an increased prevalence of conventional cardiovascular risk factors such as diabetes mellitus, hypertension, and metabolic syndrome in these patients. The aim of this study was to determine the association between psoriasis and metabolic syndrome. Material and Method: An observational cross-sectional study was carried out between November 2023 and October 2024, including participants with and without …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 15, Issue 1, 2026 · pp. 17–23 Read article
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Deep Learning-Based Pneumonia Diagnosis: A Comparative Review of Models and Metrics
Abstract: Pneumonia is a common viral infection that affects a large percentage of people worldwide. It is more common in developing and impoverished areas because of factors like poor sanitation, crowded living quarters, pollution in the environment, and restricted access to medical facilities. In order to improve survival chances and gain access to therapeutic therapies, pneumonia must be diagnosed as soon as possible. A type of artificial intelligence called deep learning …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 13, Issue 3, 2024 Read article
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CB₁ Reverse Agonists: A Cheminformatic and Patent Landscape Study
Abstract: The endocannabinoid system plays a crucial role in numerous physiological functions, making cannabinoid receptor 1 (CB1) an attractive target for therapeutic development. This review provides a systematic analysis of patent filings from 2019 to 2023 that focus on small-molecule CB1 reverse agonists. It begins with an overview of the endocannabinoid system, highlighting CB1’s involvement in energy balance, pain regulation, and neuroinflammatory processes The main section of the review examines fifteen …
Published in International Journal of Cheminformatics · Vol. 3, Issue 2, 2025 · pp. 33–36 Read article
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Challenges and Opportunities in the African Pharmaceutical Industry
Abstract: Background: The pharmaceutical industry in Africa has significant potential for growth; however, it is overwhelmed with grappling challenges. Nonetheless, these challenges can create a window of opportunities for innovation. This article provides an in-depth analysis of the profound challenges and opportunities in the continents pharmaceutical industry. Methods: Using data collected from published literature, reports and gray literature was used to conduct a narrative review. Using data collected from various publications …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 15, Issue 3, 2024 · pp. 88–98 Read article
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The Prognostic Efficacy of Inflammatory Indicators in Determining the Cause of Multiple Sclerosis Exacerbation
Abstract: Multiple sclerosis (MS) is the most prevalent immune-mediated inflammatory disease affecting the central nervous system, presenting with diverse clinical symptoms and manifestations. This study investigates the diagnostic potential of the monocyte-to-lymphocyte ratio (MLR), red cell distribution width-to-lymphocyte ratio (RLR), and systemic immune-inflammation index (SII) in detecting MS attacks among relapsing-remitting MS (RRMS) patients seeking care in the emergency department (ED). The research focused on RRMS patients who presented to the …
Published in Research and Reviews : A Journal of Immunology · Vol. 15, Issue 1, 2025 · pp. 1–8 Read article
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Abysmal Oddities of Brain in Neurological and Psychiatric Disorders Based on Sū’-i-Mizāj Māddῑ (Abnormal Substantial Temperament): Through The Lens of Greco-Arabic Medicine
Abstract: The mesmerizing history of neurological and psychiatric disorders relates to the history of humanity. The Unani philosophers apprehend neurological and psychiatric disorders superbly. They gave a conceptual understanding of the Sū’-i-Mizāj dimag and diagnosed neurological and psychiatric disorders wonderfully. Contrariwise, the Babylonians associated epilepsy, anxiety, depression, mania, and other psychiatric disorders with deities and demons earlier. To understand, analyse, and explain a comprehensive patho-physiology of neurological and psychiatric disorders, it …
Published in Research & Reviews : A Journal of Unani, Siddha and Homeopathy · Vol. 12, Issue 2, 2025 · pp. 30–42 Read article
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State of the Art: A Pandemic Big HealthCare Analytics Solution: Image Data Classification Using Quantum MAML
Abstract: The modern age is facing many pandemic healthcare problems, e.g., covid 19, infections, inflammations, and many more, leading to critical, deadly situations. Survival rate can be increased with proper diagnosis of such data. We have proposed one of the implementations based on a medical image dataset for classification using deep reinforcement learning (RL) with quantum computing. Deep RL is the combination of DL (deep learning), generative adversarial network (GAN), and …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 14, Issue 2, 2024 · pp. 1–9 Read article
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The Role of Rubella Virus Infection among Women with Spontaneous Abortion in Al-Najaf Governorate
Abstract: Rubella virus could cause a spectrum of birth defects known as Congenital Rubella Syndrome (CRS) if the infection occurs within the first or second trimester of pregnancy. Repeated miscarriage is defined as a condition with two or more consecutive abortions before the 20–25 weeks of gestation. Rubella remains to be a severe public health problem in developing countries. Recurrent miscarriage is a multi-factorial disease, which occurs in approximately 1%–2% of …
Published in International Journal of Virus Studies · Vol. 3, Issue 2, 2026 · pp. 1–6 Read article
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Molecular Docking Studies for the Identification of Mycobacterial Adenosine Triphosphate (ATP) Synthase Inhibitors Using Active Phytocompounds from Plants Curcuma longa, Curcuma zedoaria and Galipea officinalis
Abstract: Objective: Tuberculosis (TB), known in human history for several decades, remains the second leading infectious disease after COVID-19. Still, the occurrence of TB increases due to the bacterium’s greater survival nature. They can survive in extreme conditions by being in long latency and adapting to the host. This study seeks to identify potential inhibitors from Curcuma longa, Curcuma zeodaria, and Galipea officinalis based on ancient folklore and compare them against …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 2, Issue 1, 2024 · pp. 16–26 Read article
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AI-Powered IoT System for Early Detection and Monitoring of Livestock Health
Abstract: Protection of food production exists through livestock farming operations that advance economic global power. Continuous challenges to agricultural industry practices result in harmed animal health and enable disease spread as well as environmental threats to their welfare. Implementing current innovative solutions right away is necessary to solve these problems. The AI and IoT-based smart livestock health monitoring system functions as the fundamental development approach across this industry. The present integrated …
Published in International Journal of Electrical and Communication Engineering Technology · Vol. 3, Issue 1, 2025 · pp. 1–8 Read article
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Charting the Path Forward: An In-Depth Analysis of Breakthroughs and Hurdles in Artificial Intelligence
Abstract: Recent years have witnessed tremendous progress in artificial intelligence (AI), fueled by exponential increases in processing power and data accessibility. These developments have made it possible for AI to be widely used in a variety of industries, such as healthcare, finance, autonomous driving, and more. Significant difficulties are presented by the "black-box" nature of many AI systems, which lack transparency and the capacity to explain. By encouraging algorithms that can …
Published in Recent Trends in Parallel Computing · Vol. 12, Issue 1, 2025 · pp. 13–23 Read article
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Elderly Healthcare Using Federated Learning Approach
Abstract: The healthcare system for elderly people faces several challenges, which can be addressed using advanced machine learning models. These models can help monitor chronic diseases, detect falls, and provide personalized health recommendations. The study uses comprehensive datasets like MIMIC-III/IV, WESAD, and UCIHAR to explore human movements, device limitations, and the differences in fall occurrences. A detailed review of existing literature discusses current technologies for activity monitoring and fall detection, focusing …
Published in Current Trends in Information Technology · Vol. 16, Issue 1, 2025 · pp. 13–23 Read article