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1974 articles for “approach” (ranking capped at the first 2,000 matches — narrow the search to see the rest)
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Antibiotic Resistance in Microbes: History, Mechanisms, Therapeutic Approaches, and Strategies for Mitigation
Abstract: The global emergence of clinically significant antibiotic resistance is increasingly linked to the environment. Antimicrobials, metals, and biocides are just a few of the substances that are released into the environment through paths that are regulated by environmental regulators. Consequently, environmental regulators ought to be heavily involved in developing national and international antimicrobial resistance (AMR) measures. Antimicrobial compounds from pharmaceutical waste, agricultural runoff, and wastewater discharge contribute to the spread …
Published in International Journal of Antibiotics · Vol. 2, Issue 2, 2025 · pp. 1–11 Read article
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Exploring Phytochemicals from Ricinus Communis for Potential Therapeutic Applications in Rheumatoid Arthritis: An in-Silico Approach
Abstract: Aim: Rheumatoid arthritis (RA) is a long-term autoimmune condition characterized by the immune system mistakenly attacking the joints, leading to swelling, discomfort, and joint deformities. Current management strategies include anti-rheumatic drugs and biologics, which have limitations. This study aims to explore the therapeutic potential of Ricinus communis (castor bean plant) phytochemicals as plant-based therapies for autoimmune conditions, like RA. Methods: Phytochemicals from Ricinus communis were retrieved using the IMPPAT database, …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 3, Issue 1, 2025 · pp. 32–41 Read article
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A Practical Approach for Privacy Preserving in Cloud Computing Using Fully Homomorphic Encryption Scheme BFV and CKKS
Abstract: Cloud computing is a new type of computing architecture whereby data may be accessed over the Internet along with other services linked to its scalable data centers in the cloud. The risk associated with computing is increased since it provides essential services that are typically provided to any third party, making it more difficult to enable data security, privacy, confidentiality, integrity, and authentication. To reduce security risks, most users choose …
Published in Journal of Telecommunication, Switching Systems and Networks · Vol. 12, Issue 1, 2025 · pp. 1–8 Read article
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Repurposing Approved Immunomodulatory Drugs for Target Proteins in the Pancreas of European eel: A Molecular Docking Approach
Abstract: Leishmaniasis is a disease caused by tiny parasites called Leishmania, which spread to humans through the bite of an infected female sand fly. The disease manifests in three different forms, and the protein calcitonin promotes the disease’s spread. By reducing blood calcium levels, inhibiting osteoclast activity, increasing calcium excretion, and possibly playing a role in neurotransmitter modulation, calcitonin, a hormone released by vertebrates, promotes the progression of pathogenesis and lessens …
Published in International Journal of Molecular Biotechnological Research · Vol. 3, Issue 1, 2025 · pp. 12–19 Read article
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Innovative Approaches in Pediatric Drug Formulation Catering to Specialized Need: Review Article
Abstract: This detailed article review examines innovations in pediatric drug formulation, highlighting developments that cater to children’s specific healthcare needs. It covers pediatric pharmacology and advanced solutions like nanoparticle drug delivery and taste-making techniques, focusing on improving the safety, effectiveness, and acceptability of medications for young patients. The review highlights the benefits for patients, including improved adherence to treatment, fewer side effects, and better overall treatment outcomes. It also addresses regulatory …
Published in International Journal of Biochemistry and Biomolecule Research · Vol. 3, Issue 1, 2025 · pp. 35–43 Read article
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Holistic integrated approach of designing a satellite town: Introducing theories of environmental parameters like pollution free, circular economy and sustainability
Abstract: Urban regions are quite challenging to restore the quality of environment at the global level as well as posing serious threat to climatic changes. This fact is demonstrated on the grounds that around 70% of the carbon footprint is contributed from the urban sector. The authors of the present study have attempted to design a satellite town of population 50,000, partly to dilute the population density of main urban town …
Published in International Journal of Architectural Design and Planning · Vol. 3, Issue 1, 2025 · pp. 24–41 Read article
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Atmospheric Modeling: A Comprehensive Review of Numerical Approaches and Applications
Abstract: Atmospheric modeling plays a crucial role in understanding and predicting atmospheric processes, weather patterns, and climate variability. This review synthesizes current methodologies and applications across several types of atmospheric models, including numerical weather prediction (NWP), climate models, air quality models, and chemical transport models. We explore the intricacies of data assimilation, model evaluation, parameterization, and the importance of high-performance computing in advancing model accuracy and efficiency. Special emphasis is placed …
Published in International Journal of Atmosphere · Vol. 1, Issue 2, 2024 · pp. 16–21 Read article
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Understanding Leukemogenesis: Challenges and Advancements in Diagnostic Approaches
Abstract: Leukaemia development, or leukemogenesis, is a multifactorial process driven by a complex interplay of environmental, genetic, and epigenetic factors. Despite substantial advancements in technology and medicine, which have enhanced our understanding of the contributing factors, early and accurate diagnosis remains a major challenge due to the overlapping clinical features shared by the various leukaemia subtypes. This study explores the molecular and cellular mechanisms underlying leukemogenesis, while also addressing the difficulties …
Published in International Journal of Biomedical Innovations and Engineering · Vol. 3, Issue 1, 2025 · pp. 11–22 Read article
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Role of Carboxylesterases in Xenobiotic Metabolism and Detoxification: Insights for Cheminformatics Approaches
Abstract: Xenobiotics, which include a wide range of environmental pollutants, food additives, drugs, and carcinogens, are foreign chemical entities that enter the human body and may accumulate, leading to toxic effects. Phase I and phase II metabolic responses are among the detoxification procedures that are necessary to lessen these negative consequences. This review highlights the pivotal role of carboxylesterases (CES), enzymes involved in the hydrolysis of ester, amide, and thioester bonds …
Published in International Journal of Cheminformatics · Vol. 2, Issue 2, 2024 · pp. 9–17 Read article
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Neurodegeneration and Cognitive Decline: Causes, Consequences, and Treatment Approaches
Abstract: Neurodegenerative diseases gradually destroy nerve cells, often leading to fatal outcomes. The phrase includes a wide range of clinical problems, such as a variety of Neurological conditions include movement disorders, like Parkinson’s disease (PD) and progressive cognitive impairments, with Alzheimer’s disease (AD) being the most common among them. A loss of neurones and synaptic connections, typically in later life, is a prevalent feature of Usually, the onset and development of …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 3, Issue 1, 2025 · pp. 47–59 Read article
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Optimizing Sentiment Analysis with Naïve Bayes and Random Forest Techniques: A Result-based Approach
Abstract: In the increased digitalization, the sentiment analysis and classification have evolved as an eminent area to determine the polarity of positive, negative, and neutral reviews of the customers and users on products. It is an integral application field that employs supervised learning, Machine Learning, and Natural Language Processing concepts. The proposed Semantic Analysis and Classification using Naive Bayes and Random Forest system accomplishes the sentiment polarity by classifying the user …
Published in Journal of Artificial Intelligence Research & Advances · Vol. 12, Issue 2, 2025 · pp. 46–57 Read article
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Physico-Chemical Analysis of Soil Quality Parameters in Tamilnadu Region An Analytical Approach Towards Life on Land -SDG 15
Abstract: This study examines the physico-chemical properties of soil in Tamilnadu region, supporting SDG 15’s framework for sustainable land management. Soil, as a vital non-living component, plays a crucial role in ecosystem functioning by facilitating nutrient cycling, retaining water, and supporting habitats for a wide range of organisms. The research analysis key physical parameters (colour, texture, structure, porosity, density, consistency, temperature) and chemical properties, focusing on both macro and micronutrients. Various …
Published in International Journal of Solid State Innovations & Research · Vol. 3, Issue 1, 2025 · pp. 9–15 Read article
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Influence of Horizontal Crossflow on the Rayleigh-Taylor Instability: A Numerical Approach
Abstract: Rayleigh-Taylor Instability (RTI) is a typical occurrence in natural events, engineering, and industrial applications. When the lighter fluid (bottom medium) is forcing the heavier fluid (top medium) on top of the lighter fluid because of a gravitational field, then that phenomenon is called Rayleigh-Taylor instability (RTI). Despite extensive records of investigating this common phenomenon i.e., RTI with several unique boundary conditions, apparently, there are no prior investigations for the RTI …
Published in Research & Reviews : Journal of Physics · Vol. 14, Issue 1, 2025 · pp. 1–11 Read article
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Machine Learning-Based Approach for Heart Disease Prediction
Abstract: Heart disease is a significant global health challenge, with early diagnosis and prediction being essential for reducing mortality rates. Machine Learning (ML), an efficiently developing field within Artificial Intelligence, provides innovative methods for analyzing complex clinical data to predict heart disease. This review examines the basic machine learning techniques, data, and metrics used in cardiovascular disease prediction. It explores the role of supervised learning, such as decision trees and logistic …
Published in Journal of Artificial Intelligence Research & Advances · Vol. 12, Issue 2, 2025 · pp. 64–73 Read article
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Web-Based Placement Management System: A Digital Approach to Campus Hiring
Abstract: Web-based management system for placement is a complete digital platform focused on optimizing and automating the activities of campus recruitment. Placement activities are generally manual in nature and require a lot of work, which brings about inefficiencies and time lags involving students, recruiters, and placement coordinators. Such challenges are faced by the above-mentioned system that provides a single point of convergence for all students and employers, as well as coordinators, …
Published in Journal of Advanced Database Management & Systems · Vol. 12, Issue 2, 2025 · pp. 18–29 Read article
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Innovative Approaches to Luminescence: Exciton-Polariton Lasers and Quantum Confinement in 2D Materials
Abstract: The phenomenon known as luminescence occurs when an external energy of any kind excites a substance's electronic state, and the excited energy is released as light. Luminescence is the absence of heat produced by light emission. Luminescence comes in a variety of forms, including thermoluminescence, bioluminescence, and chemiluminescence. Examples of luminescence include flat-screen TVs, LED lights, and bioluminescent phytoplankton. The measurement of the emission spectrum produced when previously excited atoms …
Published in International Journal of Photochemistry and Photochemical Research · Vol. 2, Issue 1, 2024 · pp. 26–33 Read article
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Enhancing Thermal and Mechanical Performance of Polymer-Based Phase Change Materials with Graphite Nanoplatelets: A High-Efficiency Approach for Energy Storage Applications
Abstract: This study explores the performance enhancement and characterization of polymer-based phase change material (PCM) composites reinforced with graphite nanoplatelets (GNPs) for thermal management applications. The integration of GNPs significantly improved thermal conductivity, which increased from 0.38 W/m·K in pure PCM to 2.60 W/m·K with 10 wt% GNPs, marking a 580% improvement. Differential Scanning Calorimetry (DSC) analysis revealed a reduction in latent heat capacity from 180 J/g to 150 J/g—approximately 16.7%—attributed …
Published in Journal of Polymer & Composites · Vol. 13, Issue 3, 2025 · pp. 150–162 Read article
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Predicting Multiple Diseases Using Machine Learning: A Data-Driven Approach
Abstract: The increasing prevalence of chronic and life-threatening diseases highlights the need for innovative healthcare solutions that enable early detection and proactive management. The Multiple Disease Prediction Platform is a web-based system utilizing machine learning (ML) and deep learning (DL) algorithms to analyze user-inputted health data, generating real-time predictions of potential health risks. By leveraging Python’s Streamlit library, the platform provides an interactive and accessible diagnostic experience, eliminating the need for …
Published in Journal of Computer Technology & Applications · Vol. 16, Issue 2, 2025 · pp. 16–35 Read article
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Blockchain-based Land Registration: A Secure and Transparent Approach
Abstract: Traditional land registration systems have long faced challenges such as inefficiencies, lack of transparency, and security vulnerabilities due to centralized governance. The dependency on centralized entities for property record maintenance introduces risks such as data manipulation, fraudulent transactions, and unauthorized modifications. Additionally, bureaucratic procedures in these systems often lead to delays in property transfers and ownership verification. These shortcomings hinder economic development and trust among stakeholders. Blockchain technology presents an …
Published in Journal of Advanced Database Management & Systems · Vol. 12, Issue 2, 2025 · pp. 40–46 Read article
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Design, Synthesis, and Spectroscopic Elucidation of 3-Methyl-1-Phenylpyrazol-5-One: A Cheminformatics-Aided Approach to Heterocyclic Drug Scaffolds
Abstract: Pyrazolone, a notable heterocyclic compound, has drawn increasing interest due to its broad pharmacological profile and structural versatility. The synthesis, characterisation, and biological assessment of new pyrazolone derivatives are examined in this work. A comprehensive review of existing synthetic strategies is presented, emphasizing green and efficient methodologies. Novel derivatives were synthesized using varied starting materials and catalytic systems, followed by structural confirmation through spectroscopic analyses, including NMR, IR, and mass …
Published in International Journal of Cheminformatics · Vol. 3, Issue 1, 2025 · pp. 29–40 Read article